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Nat. Struct. Biol. Nov (1997); 4(11):900-3
C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site.
Brandsen J, Werten S, van der Vliet PC, Meisterernst M, Kroon J, Gros P
Abstract: The crystal structure of human replication and transcription cofactor PC4CTD reveals a dimer with two single-stranded (ss)DNA binding channels running in opposite directions to each other. This arrangement suggests a role in establishment or maintenance of melted DNA at promoters or origins of replication.
[PUBMED: 9360603] Download Biogrid Interactions in a variety of formats including PSI FormatPUBMED
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BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.