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Eukaryotic Cell Oct (2006); 5(10):1826-30
Mitogen-activated protein kinase Hog1 is essential for the response to arsenite in Saccharomyces cerevisiae-
Sotelo J, Rodriguez-Gabriel MA
Departamento de Microbiologia II- Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain-
Abstract: Here we describe, for the first time, that budding yeast mitogen-activated protein kinase Hog1 and its upstream activators Pbs2 and Ssk1 are essential for the response to arsenite- Hog1 is rapidly phosphorylated in response to arsenite and triggers a transcriptional response that involves the upregulation of genes essential for arsenite detoxification-
[PUBMED: 16920868] Download Biogrid Interactions in a variety of formats including PSI FormatPUBMED
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Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.