The BioGRID Database Seperator
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BioGRID | Network Layout for GLC7 for Saccharomyces cerevisiae
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GLC7

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: CID1, DIS2, YER133W
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Catalytic subunit of type 1 serine/threonine protein phosphatase, involved in many processes including glycogen metabolism, sporulation, and mitosis; interacts with multiple regulatory subunits; predominantly isolated with Sds22p
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [UniprotKB] | [SGD] | [Entrez Gene] | [GeneDB]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 27 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with GLC7

GLC7 was identified with 300 protein interactions and 437 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code
Role Source [Interactions]
The BioGRID Database Seperator
 SDS22
  • EGP1
  • YKL193C
    		•  The BioGRID Database Seperator Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine phosphatase (PP1), functions positively with Glc7p to promote dephosphorylation of nuclear substrates required for chromosome transmission during mitosis
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    bait/hit Ho Y (2002) [3666]
    hit Walsh EP (2002) [46]
    hit Krogan NJ (2006) [7079]
    bait/hit Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    Affinity Capture-Western
    bait/hit Hisamoto N (1995) [4]
    hit Wu X (2001) [4]
    hit Hong G (2000) [1]
    bait Peggie MW (2002) [4]
    bait/hit Pedelini L (2007) [10]
    Two-hybrid
    hit Ramaswamy NT (1998) [4]
    bait Pedelini L (2007) [10]
    hit Wong J (2007) [604]
    Dosage Rescue
    bait/hit Peggie MW (2002) [4]
    bait Hisamoto N (1995) [4]
    hit MacKelvie SH (1995) [1]
    Synthetic Lethality
    hit Bharucha JP (2008) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     REG1
  • PZF240
  • HEX2
  • SPP43
  • YDR028C
    		•  The BioGRID Database Seperator Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative regulation of glucose-repressible genes
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    hit Krogan NJ (2006) [7079]
    hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Affinity Capture-Western
    bait Tu J (1995) [3]
    bait Cui DY (2004) [4]
    Two-hybrid
    hit Sanz P (2000) [3]
    bait Wu X (2001) [4]
    bait Dombek KM (1999) [1]
    bait Tu J (1995) [3]
    bait Alms GR (1999) [1]
    hit Lenssen E (2005) [9]
    Dosage Rescue
    hit Tu J (1995) [3]
    Synthetic Rescue
    hit Huang D (1996) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTA1
  • FUN39
  • YAL043C
    		•  The BioGRID Database Seperator Subunit of holo-CPF, a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Krogan NJ (2004) [890]
    bait Gavin AC (2002) [3400]
    bait/hit Walsh EP (2002) [46]
    bait Nedea E (2003) [88]
    bait He X (2003) [27]
    bait Krogan NJ (2006) [7079]
    bait Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Reconstituted Complex
    bait He X (2005) [15]
    Biochemical Activity
    hit He X (2005) [15]
    Dosage Rescue
    bait He X (2005) [15]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BUD14
  • YAR014C
    		•  The BioGRID Database Seperator Protein involved in bud-site selection, Bud14p-Glc7p complex functions as a cortical regulator of dynein; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
    Gene Ontology: [View List]
    Two-hybrid
    bait Uetz P (2000) [875]
    hit Lenssen E (2005) [9]
    bait Knaus M (2005) [4]
    Affinity Capture-Western
    hit Lenssen E (2005) [9]
    hit Knaus M (2005) [4]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Synthetic Lethality
    bait Cullen PJ (2002) [3]
    Synthetic Rescue
    bait Cullen PJ (2002) [3]
    Phenotypic Enhancement
    bait Cullen PJ (2002) [3]
    Synthetic Growth Defect
    hit Logan MR (2008) [224]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAC1
  • YOR178C
    		•  The BioGRID Database Seperator Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Wu X (2001) [4]
    bait/hit Wu X (2001) [4]
    bait Stuart JS (1994) [3]
    Two-hybrid
    bait Stuart JS (1994) [3]
    hit Wu X (2001) [4]
    hit Venturi GM (2000) [24]
    hit Ramaswamy NT (1998) [4]
    hit Tu J (1996) [14]
    Dosage Rescue
    hit Stuart JS (1994) [3]
    Phenotypic Enhancement
    hit Hardy TA (1993) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SCD5
  • FTB1
  • YOR329C
    		•  The BioGRID Database Seperator Protein required for normal cortical actin organization and endocytosis; multicopy suppressor of clathrin deficiency; acts as a targeting subunit for protein phosphatase type 1
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    Two-hybrid
    hit Uetz P (2000) [875]
    hit Chang JS (2002) [3]
    hit Venturi GM (2000) [24]
    hit Tu J (1996) [14]
    bait Zeng G (2007) [13]
    Affinity Capture-Western
    bait Chang JS (2002) [3]
    Biochemical Activity
    hit Zeng G (2007) [13]
    Dosage Rescue
    bait Chang JS (2002) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BNI4
  • YNL233W
    		•  The BioGRID Database Seperator Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, required for localization of chitin synthase III to the bud neck via interaction with the chitin synthase III regulatory subunit Skt5p
    Gene Ontology: [View List]
    Two-hybrid
    hit Uetz P (2000) [875]
    hit Kozubowski L (2003) [3]
    bait Bharucha JP (2008) [4]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    hit Krogan NJ (2006) [7079]
    hit Collins SR (2007) [9064]
    Affinity Capture-Western
    bait/hit Kozubowski L (2003) [3]
    hit Larson JR (2008) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     REF2
  • YDR195W
    		•  The BioGRID Database Seperator RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation, and in snoRNA maturation; part of holo-CPF subcomplex APT, which associates with 3'-ends of snoRNA- and mRNA-encoding genes
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    hit Walsh EP (2002) [46]
    bait Nedea E (2003) [88]
    bait Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Two-hybrid
    hit Uetz P (2000) [875]
    hit Lenssen E (2005) [9]
    hit Nedea E (2008) [27]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GLC8
  • YMR311C
    		•  The BioGRID Database Seperator Regulatory subunit of protein phosphatase 1 (Glc7p), involved in glycogen metabolism and chromosome segregation; proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Ho Y (2002) [3666]
    hit Krogan NJ (2006) [7079]
    hit Collins SR (2007) [9064]
    Two-hybrid
    hit Venturi GM (2000) [24]
    hit Ramaswamy NT (1998) [4]
    bait Wong J (2007) [604]
    Synthetic Lethality
    hit Venturi GM (2000) [24]
    Synthetic Rescue
    hit Tung HY (1995) [3]
    hit Venturi GM (2000) [24]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YPI1
  • YFR003C
    		•  The BioGRID Database Seperator Inhibitor of the type I protein phosphatase Glc7p, which is involved in regulation of a variety of metabolic processes; overproduction causes decreased cellular content of glycogen
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Hazbun TR (2003) [169]
    bait/hit Ho Y (2002) [3666]
    bait Krogan NJ (2006) [7079]
    Reconstituted Complex
    bait Garcia-Gimeno MA (2003) [2]
    Two-hybrid
    hit Tu J (1996) [14]
    bait Pedelini L (2007) [10]
    Affinity Capture-Western
    bait/hit Pedelini L (2007) [10]
    Synthetic Lethality
    hit Bharucha JP (2008) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CFT1
  • YHH1
  • YDR301W
    		•  The BioGRID Database Seperator RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in poly(A) site recognition and required for both pre-mRNA cleavage and polyadenylation, 51% sequence similarity with mammalian AAUAA-binding subunit of CPSF
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    hit Ho Y (2002) [3666]
    hit Walsh EP (2002) [46]
    bait/hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Affinity Capture-Western
    hit He X (2005) [15]
    Biochemical Activity
    hit He X (2005) [15]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SWD2
  • CPS35
  • SAF37
  • YKL018W
    		•  The BioGRID Database Seperator Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lys 4 and is involved in telomeric silencing; subunit of CPF (cleavage and polyadenylation factor), a complex involved in RNAP II transcription termination
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    bait Nedea E (2003) [88]
    bait Roguev A (2001) [60]
    bait Krogan NJ (2006) [7079]
    hit Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    Two-hybrid
    hit Nedea E (2008) [27]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GIP1
  • YBR045C
    		•  The BioGRID Database Seperator Meiosis-specific regulatory subunit of the Glc7p protein phosphatase, regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p
    Gene Ontology: [View List]
    Two-hybrid
    hit Uetz P (2000) [875]
    hit Venturi GM (2000) [24]
    hit Ramaswamy NT (1998) [4]
    hit Tu J (1996) [14]
    Affinity Capture-Western
    hit Tu J (1996) [14]
    bait Tachikawa H (2001) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YSH1
  • BRR5
  • YLR277C
    		•  The BioGRID Database Seperator Putative endoribonuclease, subunit of the mRNA cleavage and polyadenylation specificity complex required for 3' processing of mRNAs
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    hit Walsh EP (2002) [46]
    bait/hit Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    Affinity Capture-Western
    hit He X (2005) [15]
    Biochemical Activity
    hit He X (2005) [15]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEN1
  • CIK3
  • NRD2
  • YLR430W
    		•  The BioGRID Database Seperator Presumed helicase required for RNA polymerase II transcription termination and processing of RNAs; homolog of Senataxin which causes Ataxia-Oculomotor Apraxia 2 and a dominant form of amyotrophic lateral sclerosis
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    hit Walsh EP (2002) [46]
    bait Nedea E (2008) [27]
    Two-hybrid
    bait/hit Nedea E (2008) [27]
    Affinity Capture-Western
    hit Nedea E (2008) [27]
    Biochemical Activity
    hit Nedea E (2008) [27]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTI1
  • YGR156W
    		•  The BioGRID Database Seperator Pta1p Interacting protein
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Nedea E (2003) [88]
    hit Krogan NJ (2006) [7079]
    hit Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    Reconstituted Complex
    bait He X (2005) [15]
    Dosage Rescue
    bait He X (2005) [15]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CFT2
  • YDH1
  • YLR115W
    		•  The BioGRID Database Seperator Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein.
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    hit Walsh EP (2002) [46]
    bait Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    Affinity Capture-Western
    hit He X (2005) [15]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PFS2
  • YNL317W
    		•  The BioGRID Database Seperator Integral subunit of the pre-mRNA cleavage and polyadenylation factor (CPF) complex; plays an essential role in mRNA 3'-end formation by bridging different processing factors and thereby promoting the assembly of the processing complex
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    bait Dichtl B (2002) [25]
    bait Krogan NJ (2006) [7079]
    bait Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RED1
  • YLR263W
    		•  The BioGRID Database Seperator Protein component of the axial elements of the synaptonemal complex, involved in chromosome segregation during the first meiotic division; interacts with Hop1p; required for wild-type levels of Mek1p kinase activity
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Bailis JM (2000) [5]
    Reconstituted Complex
    hit Bailis JM (2000) [5]
    Two-hybrid
    hit Venturi GM (2000) [24]
    hit Tu J (1996) [14]
    Biochemical Activity
    hit Bailis JM (2000) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FIP1
  • YJR093C
    		•  The BioGRID Database Seperator Subunit of cleavage polyadenylation factor (CPF), interacts directly with poly(A) polymerase (Pap1p) to regulate its activity
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    bait Krogan NJ (2006) [7079]
    bait Dheur S (2005) [18]
    hit Collins SR (2007) [9064]
    Biochemical Activity
    hit He X (2005) [15]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SLA1
  • YBL007C
    		•  The BioGRID Database Seperator Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains
    Gene Ontology: [View List]
    Two-hybrid
    hit Venturi GM (2000) [24]
    hit Tu J (1996) [14]
    hit Gardiner FC (2007) [2]
    Reconstituted Complex
    bait Gardiner FC (2007) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GIP2
  • YER054C
    		•  The BioGRID Database Seperator Putative regulatory subunit of the protein phosphatase Glc7p, involved in glycogen metabolism; contains a conserved motif (GVNK motif) that is also found in Gac1p, Pig1p, and Pig2p
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ho Y (2002) [3666]
    Two-hybrid
    hit Venturi GM (2000) [24]
    hit Tu J (1996) [14]
    hit Lenssen E (2005) [9]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAP1
  • YKR002W
    		•  The BioGRID Database Seperator Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    hit Walsh EP (2002) [46]
    bait/hit Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GIP3
  • YPL137C
    		•  The BioGRID Database Seperator Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    hit Krogan NJ (2006) [7079]
    hit Graumann J (2004) [478]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOL2
  • YCRX13W
  • YCR073W-A
    		•  The BioGRID Database Seperator Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol1p, Sol3p, and Sol4p
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    hit Gavin AC (2006) [7592]
    hit Graumann J (2004) [478]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MPE1
  • YKL059C
    		•  The BioGRID Database Seperator Essential conserved subunit of CPF (cleavage and polyadenylation factor), plays a role in 3' end formation of mRNA via the specific cleavage and polyadenylation of pre-mRNA, contains a putative RNA-binding zinc knuckle motif
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    bait Nedea E (2003) [88]
    bait Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ADE16
  • YLR028C
    		•  The BioGRID Database Seperator Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade17p; ade16 ade17 mutants require adenine and histidine
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    bait/hit Gavin AC (2006) [7592]
    hit Graumann J (2004) [478]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BMH1
  • APR6
  • YER177W
    		•  The BioGRID Database Seperator 14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2006) [7592]
    hit Graumann J (2004) [478]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MHP1
  • YJL042W
    		•  The BioGRID Database Seperator Microtubule-associated protein involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Ho Y (2002) [3666]
    hit Walsh EP (2002) [46]
    Two-hybrid
    hit Uetz P (2000) [875]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SYC1
  • YOR179C
    		•  The BioGRID Database Seperator Subunit of the APT subcomplex of cleavage and polyadenylation factor, may have a role in 3' end formation of both polyadenylated and non-polyadenylated RNAs
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    bait Gavin AC (2006) [7592]
    bait Nedea E (2008) [27]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     REG2
  • YBR050C
    		•  The BioGRID Database Seperator Regulatory subunit of the Glc7p type-1 protein phosphatase; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Frederick DL (1996) [4]
    Two-hybrid
    hit Venturi GM (2000) [24]
    hit Lenssen E (2005) [9]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YTH1
  • YPR107C
    		•  The BioGRID Database Seperator Essential RNA-binding component of cleavage and polyadenylation factor, contains five zinc fingers; required for pre-mRNA 3'-end processing and polyadenylation
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    bait Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FIN1
  • YDR130C
    		•  The BioGRID Database Seperator Spindle pole body-related intermediate filament protein, forms cell cycle-specific filaments between spindle pole bodies in mother and daughter cells, able to self-assemble, expression induced during S/G2, localization cell-cycle dependent
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    Two-hybrid
    hit Uetz P (2000) [875]
    Affinity Capture-Western
    hit Mayordomo I (2002) [15]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YOR227W
  • YOR227W
    		•  The BioGRID Database Seperator Protein of unknown function that may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Ho Y (2002) [3666]
    hit Walsh EP (2002) [46]
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BUD27
  • URI1
  • YFL023W
    		•  The BioGRID Database Seperator Protein involved in bud-site selection, nutrient signaling, and gene expression controlled by the TOR kinase; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
    Gene Ontology: [View List]
    Two-hybrid
    hit Venturi GM (2000) [24]
    hit Tu J (1996) [14]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AFR1
  • YDR085C
    		•  The BioGRID Database Seperator Alpha-factor pheromone receptor regulator, negatively regulates pheromone receptor signaling; required for normal mating projection (shmoo) formation; required for Spa2p to recruit Mpk1p to shmoo tip during mating; interacts with Cdc12p
    Gene Ontology: [View List]
    Two-hybrid
    bait Bharucha JP (2008) [4]
    FRET
    bait Bharucha JP (2008) [4]
    Positive Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GSY2
  • YLR258W
    		•  The BioGRID Database Seperator Glycogen synthase, similar to Gsy1p; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    hit Gavin AC (2006) [7592]
    Synthetic Rescue
    hit Anderson C (2001) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIP5
  • YMR140W
    		•  The BioGRID Database Seperator Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and the Snf1p kinase
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Sanz P (2000) [4]
    Two-hybrid
    hit Sanz P (2000) [4]
    Synthetic Lethality
    hit Logan MR (2008) [224]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IPL1
  • PAC15
  • YPL209C
    		•  The BioGRID Database Seperator Aurora kinase involved in regulating kinetochore-microtubule attachments; helps maintain condensed chromosomes during anaphase and early telophase; associates with Sli15p, which promotes Ipl1p association with mitotic spindle
    Gene Ontology: [View List]
    Dosage Lethality
    bait Francisco L (1994) [2]
    Synthetic Rescue
    bait Francisco L (1994) [2]
    bait Pinsky BA (2006) [10]
    bait Bharucha JP (2008) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LSM12
  • YHR121W
    		•  The BioGRID Database Seperator Protein of unknown function that may function in RNA processing; interacts with Pbp1p and Pbp4p and associates with ribosomes; contains an RNA-binding LSM domain and an AD domain; GFP-fusion protein is induced by the DNA-damaging agent MMS
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    Positive Genetic
    bait Wilmes GM (2008) [6467]
    Synthetic Lethality
    hit Logan MR (2008) [224]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BMH2
  • SCD3
  • YDR099W
    		•  The BioGRID Database Seperator 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    hit Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SYN8
  • SLT2
  • UIP2
  • YAL014C
    		•  The BioGRID Database Seperator Endosomal SNARE related to mammalian syntaxin 8
    Gene Ontology: [View List]
    Two-hybrid
    hit Venturi GM (2000) [24]
    hit Tu J (1996) [14]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JIP4
  • YDR474C
  • YDR475C
    		•  The BioGRID Database Seperator Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    hit Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAN1
  • MIP3
  • MDP3
  • DIM2
  • YIR006C
    		•  The BioGRID Database Seperator Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on the cell cortex; promotes protein-protein interactions essential for endocytosis; previously thought to be a subunit of poly(A) ribonuclease
    Gene Ontology: [View List]
    Two-hybrid
    hit Uetz P (2000) [875]
    Biochemical Activity
    hit Zeng G (2007) [13]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FPR3
  • NPI46
  • YML074C
    		•  The BioGRID Database Seperator Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    Affinity Capture-Western
    hit Hochwagen A (2005) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSU72
  • YNL222W
    		•  The BioGRID Database Seperator Transcription/RNA-processing factor that associates with TFIIB and cleavage/polyadenylation factor Pta1p; exhibits phosphatase activity on serine-5 of the RNA polymerase II C-terminal domain; affects start site selection in vivo
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Nedea E (2003) [88]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RRP17
  • YDR412W
    		•  The BioGRID Database Seperator Protein required for cell viability
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    Two-hybrid
    hit Uetz P (2000) [875]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BDF2
  • YDL070W
    		•  The BioGRID Database Seperator Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p
    Gene Ontology: [View List]
    Two-hybrid
    hit Uetz P (2000) [875]
    hit Wong J (2007) [604]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YTA6
  • YPL074W
    		•  The BioGRID Database Seperator Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family, localized to the cortex of mother cells but not to daughter cells
    Gene Ontology: [View List]
    Two-hybrid
    hit Venturi GM (2000) [24]
    hit Tu J (1996) [14]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HCA4
  • ECM24
  • DBP4
  • YJL033W
    		•  The BioGRID Database Seperator Putative nucleolar DEAD box RNA helicase; high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    bait Gavin AC (2006) [7592]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SLT2
  • BYC2
  • MPK1
  • SLK2
  • YHR030C
    		•  The BioGRID Database Seperator Serine/threonine MAP kinase involved in regulating the maintenance of cell wall integrity and progression through the cell cycle; regulated by the PKC1-mediated signaling pathway
    Gene Ontology: [View List]
    Dosage Rescue
    hit Andrews PD (2000) [9]
    Phenotypic Enhancement
    bait Andrews PD (2000) [9]
    Synthetic Lethality
    bait Andrews PD (2000) [9]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RTT103
  • YDR289C
    		•  The BioGRID Database Seperator Protein that interacts with exonuclease Rat1p and Rai1p and plays a role in transcription termination by RNA polymerase II, has an RPR domain (carboxy-terminal domain interacting domain); also involved in regulation of Ty1 transposition
    Gene Ontology: [View List]
    Positive Genetic
    bait Wilmes GM (2008) [6467]
    hit Costanzo M (2010) [68487]
    Synthetic Lethality
    hit Logan MR (2008) [224]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCL1
  • TRM4
  • YBL024W
    		•  The BioGRID Database Seperator S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; similar to Nop2p and human proliferation associated nucleolar protein p120
    Gene Ontology: [View List]
    Positive Genetic
    bait Wilmes GM (2008) [6467]
    hit Costanzo M (2010) [68487]
    Synthetic Growth Defect
    hit Logan MR (2008) [224]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NPL3
  • MTR13
  • MTS1
  • NAB1
  • YDR432W
    		•  The BioGRID Database Seperator RNA-binding protein that carries poly(A)+ mRNA from the nucleus into the cytoplasm; dissociation from mRNAs is promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Gilbert W (2004) [2]
    Negative Genetic
    bait Wilmes GM (2008) [6467]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL8A
  • MAK7
  • YHL033C
    		•  The BioGRID Database Seperator Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Bp and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBI4
  • SCD2
  • UB14
  • YLL039C
    		•  The BioGRID Database Seperator Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Peng J (2003) [1092]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS1A
  • RP10A
  • YLR441C
    		•  The BioGRID Database Seperator Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Bp and has similarity to rat S3a ribosomal protein
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    Synthetic Growth Defect
    hit Logan MR (2008) [224]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GPH1
  • YPR160W
    		•  The BioGRID Database Seperator Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulated by cyclic AMP-mediated phosphorylation, expression is regulated by stress-response elements and by the HOG MAP kinase pathway
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    Synthetic Growth Defect
    hit Logan MR (2008) [224]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YER158C
  • YER158C
    		•  The BioGRID Database Seperator Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Graumann J (2004) [478]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FPR4
  • YLR449W
    		•  The BioGRID Database Seperator Peptidyl-prolyl cis-trans isomerase (PPIase) (proline isomerase) localized to the nucleus; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    Synthetic Growth Defect
    hit Logan MR (2008) [224]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BRR1
  • YPR057W
    		•  The BioGRID Database Seperator snRNP protein component of spliceosomal snRNPs, required for pre-mRNA splicing and snRNP biogenesis; in null mutant newly-synthesized snRNAs are destabilized and 3'-end processing is slowed
    Gene Ontology: [View List]
    Positive Genetic
    bait Wilmes GM (2008) [6467]
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KTR4
  • YBR199W
    		•  The BioGRID Database Seperator Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Logan MR (2008) [224]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BTS1
  • YPL069C
    		•  The BioGRID Database Seperator Geranylgeranyl diphosphate synthase, increases the intracellular pool of geranylgeranyl diphosphate, suppressor of bet2 mutation that causes defective geranylgeranylation of small GTP-binding proteins that mediate vesicular traffic
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Logan MR (2008) [224]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KAR3
  • OSR11
  • YPR141C
    		•  The BioGRID Database Seperator Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Logan MR (2008) [224]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CIK1
  • YMR198W
    		•  The BioGRID Database Seperator Kinesin-associated protein required for both karyogamy and mitotic spindle organization, interacts stably and specifically with Kar3p and may function to target this kinesin to a specific cellular role; has similarity to Vik1p
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Logan MR (2008) [224]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAD2
  • YJL030W
    		•  The BioGRID Database Seperator Component of the spindle-assembly checkpoint complex, which delays the onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Logan MR (2008) [224]
    Synthetic Rescue
    hit Pinsky BA (2009) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PHO23
  • YNL097C
    		•  The BioGRID Database Seperator Probable component of the Rpd3 histone deacetylase complex, involved in transcriptional regulation of PHO5; C-terminus has similarity to human candidate tumor suppressor p33(ING1)
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Logan MR (2008) [224]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CKB1
  • YGL019W
    		•  The BioGRID Database Seperator Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB2, the many substrates include transcription factors and all RNA polymerases
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Logan MR (2008) [224]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RMT2
  • YDR465C
    		•  The BioGRID Database Seperator Arginine methyltransferase; ribosomal protein L12 is a substrate
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Logan MR (2008) [224]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AMD2
  • YDR242W
    		•  The BioGRID Database Seperator Putative amidase
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Logan MR (2008) [224]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NUP133
  • RAT3
  • YKR082W
    		•  The BioGRID Database Seperator Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), localizes to both sides of the NPC, required to establish a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Logan MR (2008) [224]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ELP2
  • TOT2
  • YGR200C
    		•  The BioGRID Database Seperator Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; target of Kluyveromyces lactis zymocin
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Logan MR (2008) [224]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAT1
  • MRT1
  • YCR077C
    		•  The BioGRID Database Seperator Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; functionally linked to Pab1p
    Gene Ontology: [View List]
    Negative Genetic
    hit Wilmes GM (2008) [6467]
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRK1
  • PAK1
  • YIL095W
    		•  The BioGRID Database Seperator Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton through the phosphorylation of the Pan1p-Sla1p-End3p protein complex
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Zeng G (2007) [13]
    Synthetic Rescue
    hit Zeng G (2007) [13]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MOT2
  • NOT4
  • SIG1
  • YER068W
    		•  The BioGRID Database Seperator Component of the CCR4-NOT complex, which has multiple roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; with Ubc4p, ubiquitylates subunits of the nascent polypeptide-associated complex (NAC)
    Gene Ontology: [View List]
    Synthetic Rescue
    bait Lenssen E (2005) [9]
    Phenotypic Suppression
    bait Lenssen E (2005) [9]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ROM2
  • YLR371W
    		•  The BioGRID Database Seperator GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEP
    Gene Ontology: [View List]
    Dosage Rescue
    hit Andrews PD (2000) [9]
    Synthetic Lethality
    hit Logan MR (2008) [224]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LSM1
  • SPB8
  • YJL124C
    		•  The BioGRID Database Seperator Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs
    Gene Ontology: [View List]
    Negative Genetic
    hit Wilmes GM (2008) [6467]
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SAC3
  • LEP1
  • YDR159W
    		•  The BioGRID Database Seperator Nuclear pore-associated protein, forms a complex with Thp1p that is involved in transcription and in mRNA export from the nucleus
    Gene Ontology: [View List]
    Negative Genetic
    bait Wilmes GM (2008) [6467]
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS25A
  • RPS31A
  • YGR027C
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Bp and has similarity to rat S25 ribosomal protein
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Logan MR (2008) [224]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD4
  • YER162C
    		•  The BioGRID Database Seperator Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human XPC protein
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Logan MR (2008) [224]
    Positive Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS8A
  • YBL072C
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit; identical to Rps8Bp and has similarity to rat S8 ribosomal protein
    Gene Ontology: [View List]
    Positive Genetic
    hit Wilmes GM (2008) [6467]
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DAM1
  • YGR113W
    		•  The BioGRID Database Seperator Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; Ipl1p target for regulating kinetochore-MT attachments
    Gene Ontology: [View List]
    Dosage Lethality
    bait Kang J (2001) [10]
    Synthetic Lethality
    bait Cheeseman IM (2002) [28]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SXM1
  • KAP108
  • YDR395W
    		•  The BioGRID Database Seperator Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm; similar to Nmd5p, Cse1p, Lph2p, and the human cellular apoptosis susceptibility protein, CAS1
    Gene Ontology: [View List]
    Positive Genetic
    bait Wilmes GM (2008) [6467]
    Synthetic Growth Defect
    hit Logan MR (2008) [224]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NSA1
  • YGL111W
    		•  The BioGRID Database Seperator Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HRR25
  • YPL204W
    		•  The BioGRID Database Seperator Protein kinase involved in regulating diverse events including vesicular trafficking, DNA repair, and chromosome segregation; binds the CTD of RNA pol II; homolog of mammalian casein kinase 1delta (CK1delta)
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL3
  • MAK8
  • YOR29-14
  • TCM1
  • YOR063W
    		•  The BioGRID Database Seperator Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL20B
  • RPL18A1
  • YOR312C
    		•  The BioGRID Database Seperator Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Ap and has similarity to rat L18a ribosomal protein
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL20A
  • RPL18A2
  • YMR242C
    		•  The BioGRID Database Seperator Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Bp and has similarity to rat L18a ribosomal protein
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL14A
  • YKL006W
    		•  The BioGRID Database Seperator N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl14Bp and has similarity to rat L14 ribosomal protein; rpl14a csh5 double null mutant exhibits synthetic slow growth
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL14B
  • YHL001W
    		•  The BioGRID Database Seperator Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl14Ap and has similarity to rat L14 ribosomal protein
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SPB1
  • YCL054W
    		•  The BioGRID Database Seperator AdoMet-dependent methyltransferase involved in rRNA processing and 60S ribosomal subunit maturation; methylates G2922 in the tRNA docking site of the large subunit rRNA and in the absence of snR52, U2921; suppressor of PAB1 mutants
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL33A
  • YPL143W
    		•  The BioGRID Database Seperator N-terminally acetylated ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Bp and has similarity to rat L35a; rpl33a null mutant exhibits slow growth while rpl33a rpl33b double null mutant is inviable
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSB1
  • YG101
  • YDL229W
    		•  The BioGRID Database Seperator Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in folding of newly-made polypeptide chains; member of the HSP70 family; interacts with phosphatase subunit Reg1p
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Gong Y (2009) [1420]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL8B
  • KRB1
  • SCL41
  • YLL045C
    		•  The BioGRID Database Seperator Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPP0
  • RPL10E
  • YLR340W
    		•  The BioGRID Database Seperator Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphorylated on serine 302
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC5
  • PKX2
  • MSD2
  • YMR001C
    		•  The BioGRID Database Seperator Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bud neck, nucleus and SPBs; has multiple functions in mitosis and cytokinesis through phosphorylation of substrates; may be a Cdc28p substrate
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Matos J (2008) [53]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TPK3
  • YKL166C
    		•  The BioGRID Database Seperator cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk2p
    Gene Ontology: [View List]
    Two-hybrid
    hit Sharan R (2005) [19]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL33B
  • YOR234C
    		•  The BioGRID Database Seperator Ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Ap and has similarity to rat L35a; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NAB2
  • YGL122C
    		•  The BioGRID Database Seperator Nuclear polyadenylated RNA-binding protein; autoregulates mRNA levels; related to human hnRNPs; has nuclear localization signal sequence that binds to Kap104p; required for poly(A) tail length control and nuclear mRNA export
    Gene Ontology: [View List]
    Affinity Capture-RNA
    bait Batisse J (2009) [2548]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPA190
  • RRN1
  • YOR341W
    		•  The BioGRID Database Seperator RNA polymerase I subunit; largest subunit of RNA polymerase I
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ERB1
  • YMR049C
    		•  The BioGRID Database Seperator Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MDH1
  • YKL085W
    		•  The BioGRID Database Seperator Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YTM1
  • YOR272W
    		•  The BioGRID Database Seperator Constituent of 66S pre-ribosomal particles, required for maturation of the large ribosomal subunit
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YPT31
  • YPT8
  • YER031C
    		•  The BioGRID Database Seperator GTPase of the Ypt/Rab family, very similar to Ypt32p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi
    Gene Ontology: [View List]
    Two-hybrid
    hit Tu J (1996) [14]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KEL1
  • YHR158C
    		•  The BioGRID Database Seperator Protein required for proper cell fusion and cell morphology; functions in a complex with Kel2p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CLU1
  • TIF31
  • YMR012W
    		•  The BioGRID Database Seperator eIF3 component of unknown function; deletion causes defects in mitochondrial organization but not in growth or translation initiation, can rescue cytokinesis and mitochondrial organization defects of the Dictyostelium cluA- mutant
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDC5
  • YLR134W
    		•  The BioGRID Database Seperator Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde, regulation is glucose- and ethanol-dependent, repressed by thiamine, involved in amino acid catabolism
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ADH4
  • ZRG5
  • NRC465
  • YGL256W
    		•  The BioGRID Database Seperator Alcohol dehydrogenase isoenzyme type IV, dimeric enzyme demonstrated to be zinc-dependent despite sequence similarity to iron-activated alcohol dehydrogenases; transcription is induced in response to zinc deficiency
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NOP7
  • YPH1
  • YGR103W
    		•  The BioGRID Database Seperator Nucleolar protein involved in rRNA processing and 60S ribosomal subunit biogenesis; constituent of several different pre-ribosomal particles; required for exit from G0 and the initiation of cell proliferation
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SUI3
  • YPL237W
    		•  The BioGRID Database Seperator Beta subunit of the translation initiation factor eIF2, involved in the identification of the start codon; proposed to be involved in mRNA binding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CIC1
  • NSA3
  • YHR052W
    		•  The BioGRID Database Seperator Essential protein that interacts with proteasome components and has a potential role in proteasome substrate specificity; also copurifies with 66S pre-ribosomal particles
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SFG1
  • YOR315W
    		•  The BioGRID Database Seperator Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate
    Gene Ontology: [View List]
    Two-hybrid
    hit Uetz P (2000) [875]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GSY1
  • YFR015C
    		•  The BioGRID Database Seperator Glycogen synthase with similarity to Gsy2p, the more highly expressed yeast homolog; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YHR100C
  • YHR100C
    		•  The BioGRID Database Seperator Putative protein of unknown function, required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
    Gene Ontology: [View List]
    Two-hybrid
    hit Uetz P (2000) [875]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SUI2
  • YJR007W
    		•  The BioGRID Database Seperator Alpha subunit of the translation initiation factor eIF2, involved in the identification of the start codon; phosphorylation of Ser51 is required for regulation of translation by inhibiting the exchange of GDP for GTP
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC14
  • OAF3
  • YFR028C
    		•  The BioGRID Database Seperator Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPP1R2
  • MGC87148
  • IPP2
    		•  The BioGRID Database Seperator protein phosphatase 1, regulatory (inhibitor) subunit 2
    Gene Ontology: [View List]
    Two-hybrid
    bait Terry-Lorenzo RT (2002) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL27A
  • RPL27
  • YHR010W
    		•  The BioGRID Database Seperator Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PGK1
  • YCR012W
    		•  The BioGRID Database Seperator 3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phosphate of 1,3-bisphosphoglycerate to ADP to produce ATP; key enzyme in glycolysis and gluconeogenesis
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS22B
  • YLR367W
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Walsh EP (2002) [46]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAM33
  • YIL070C
    		•  The BioGRID Database Seperator Acidic protein of the mitochondrial matrix involved in oxidative phosphorylation; related to the human complement receptor gC1q-R
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MSN2
  • YMR037C
    		•  The BioGRID Database Seperator Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
    Gene Ontology: [View List]
    Biochemical Activity
    hit De Wever V (2005) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     POL2
  • DUN2
  • YNL262W
    		•  The BioGRID Database Seperator Catalytic subunit of DNA polymerase (II) epsilon, one of the major chromosomal DNA replication polymerases characterized by processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPP2A
  • RPL44
  • RPLA2
  • YOL039W
    		•  The BioGRID Database Seperator Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CKA1
  • YIL035C
    		•  The BioGRID Database Seperator Alpha catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA2, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDC1
  • YLR044C
    		•  The BioGRID Database Seperator Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde; subject to glucose-, ethanol-, and autoregulation; involved in amino acid catabolism
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GIP4
  • FUN21
  • YAL031C
    		•  The BioGRID Database Seperator Cytoplasmic Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; potential Cdc28p substrate
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CCR4
  • FUN27
  • NUT21
  • YAL021C
    		•  The BioGRID Database Seperator Component of the CCR4-NOT transcriptional complex, which is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AHP1
  • YLR109W
    		•  The BioGRID Database Seperator Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPP1R15A
  • GADD34
    		•  The BioGRID Database Seperator protein phosphatase 1, regulatory (inhibitor) subunit 15A
    Gene Ontology: [View List]
    Two-hybrid
    hit Connor JH (2001) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CKA2
  • YOR29-12
  • YOR061W
    		•  The BioGRID Database Seperator Alpha' catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ADE17
  • YMR120C
    		•  The BioGRID Database Seperator Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade16p; ade16 ade17 mutants require adenine and histidine
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ABF1
  • BAF1
  • OBF1
  • REB2
  • YKL112W
    		•  The BioGRID Database Seperator DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ENO1
  • HSP48
  • YGR254W
    		•  The BioGRID Database Seperator Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is repressed in response to glucose
    Gene Ontology: [View List]
    Affinity Capture-MS </
    hit Graumann J (2004) [478]