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BioGRID | Network Layout for WBP1 for Saccharomyces cerevisiae
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WBP1

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: YEL002C
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Beta subunit of the oligosaccharyl transferase (OST) glycoprotein complex; required for N-linked glycosylation of proteins in the endoplasmic reticulum|Wbp1p; protein coding
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [GeneDB]  [Germ Online]  [SGD]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 6 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with WBP1

WBP1 was identified with 90 protein interactions and 77 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 SWP1
  • YMR149W
    		•  The BioGRID Database Seperator Delta subunit of the oligosaccharyl transferase glycoprotein complex, which is required for N-linked glycosylation of proteins in the endoplasmic reticulum|Swp1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002)
    bait/hit Gavin AC (2006)
    hit Collins SR (2007)
    Two-hybrid
    bait Miller JP (2005)
    hit Yan A (2005)
    Affinity Capture-Western
    bait/hit Yan A (2003)
    bait te Heesen S (1993)
    hit Li G (2003)
    Co-purification
    hit Knauer R (1994)
    Dosage Rescue
    hit te Heesen S (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     OST1
  • NLT1
  • YJL002C
    		•  The BioGRID Database Seperator Alpha subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins|Ost1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    bait Gavin AC (2006)
    Affinity Capture-Western
    bait/hit Yan A (2003)
    hit Li G (2003)
    Two-hybrid
    hit Scheper W (2003)
    hit Yan A (2005)
    bait/hit Yan A (2005)
    Co-purification
    bait Pathak R (1997)
    bait Spirig U (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STT3
  • YGL022W
    		•  The BioGRID Database Seperator Stt3p|Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; forms a subcomplex with Ost3p and Ost4p and is directly involved in catalysis; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    bait Spirig U (1997)
    bait Gavin AC (2006)
    hit Collins SR (2007)
    Affinity Capture-Western
    bait/hit Yan A (2003)
    hit Li G (2003)
    Two-hybrid
    hit Yan A (2005)
    Co-purification
    bait Spirig U (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     OST6
  • YML019W
    		•  The BioGRID Database Seperator Ost6p|Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; similar to and partially functionally redundant with Ost3p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Yan A (2003)
    bait Yan A (2005)
    Two-hybrid
    hit Yan A (2005)
    bait/hit Yan A (2005)
    Co-purification
    bait Schwarz M (2005)
    Phenotypic Enhancement
    bait/hit Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     OST3
  • YOR085W
    		•  The BioGRID Database Seperator Gamma subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; Ost3p is important for N-glycosylation of a subset of proteins|Ost3p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Karaoglu D (1997)
    bait/hit Yan A (2003)
    Two-hybrid
    bait/hit Yan A (2005)
    Co-purification
    bait Schwarz M (2005)
    Phenotypic Enhancement
    bait Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ALG5
  • YPL227C
    		•  The BioGRID Database Seperator Alg5p|UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Miller JP (2005)
    Phenotypic Enhancement
    hit Stagljar I (1994)
    bait/hit Schuldiner M (2005)
    Synthetic Growth Defect
    bait Stagljar I (1994)
    Synthetic Lethality
    bait Reiss G (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSS1
  • YDR086C
    		•  The BioGRID Database Seperator Sss1p|Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) that forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Scheper W (2003)
    Two-hybrid
    hit Scheper W (2003)
    bait Chavan M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SBH1
  • SEB1
  • YER087C-A
  • YER087C-B
    		•  The BioGRID Database Seperator Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involved in protein translocation into the endoplasmic reticulum; interacts with the exocyst complex and also with Rtn1p; homologous to Sbh2p|Sbh1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Scheper W (2003)
    Two-hybrid
    bait Chavan M (2005)
    bait/hit Yan A (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     OST2
  • YOR103C
    		•  The BioGRID Database Seperator Epsilon subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins|Ost2p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Yan A (2003)
    Two-hybrid
    hit Yan A (2005)
    Dosage Rescue
    hit Silberstein S (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PKC1
  • CLY15
  • HPO2
  • STT1
  • YBL105C
    		•  The BioGRID Database Seperator Pkc1p|Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC); protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Park H (2000)
    Two-hybrid
    bait Park H (2000)
    Dosage Rescue
    bait Park H (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     OST5
  • YGL226C-A
    		•  The BioGRID Database Seperator Ost5p|Zeta subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Yan A (2003)
    Two-hybrid
    hit Yan A (2005)
    Phenotypic Enhancement
    bait Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KEX1
  • YGL203C
    		•  The BioGRID Database Seperator Kex1p|Protease involved in the processing of killer toxin and alpha factor precursor; cleaves Lys and Arg residues from the C-terminus of peptides and proteins; protein coding
    Gene Ontology: [View List]
    Synthetic Rescue
    hit Hauptmann P (2008)
    Phenotypic Suppression
    hit Hauptmann P (2008)
    Dosage Growth Defect
    hit Hauptmann P (2008)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ALG8
  • YOR29-18
  • YOR067C
    		•  The BioGRID Database Seperator Alg8p|Glucosyl transferase, involved in N-linked glycosylation; adds glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein during lipid-linked oligosaccharide biosynthesis; similar to Alg6p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Stagljar I (1994)
    bait Schuldiner M (2005)
    Synthetic Growth Defect
    bait Stagljar I (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ALG6
  • YOR002W
    		•  The BioGRID Database Seperator Alg6p|Alpha 1,3 glucosyltransferase, involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation; mutations in human ortholog are associated with disease; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Stagljar I (1994)
    bait/hit Schuldiner M (2005)
    Synthetic Growth Defect
    bait Stagljar I (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PHO88
  • YBR106W
    		•  The BioGRID Database Seperator Pho88p|Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Miller JP (2005)
    Phenotypic Suppression
    bait Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STE24
  • AFC1
  • PIO2
  • YJR117W
    		•  The BioGRID Database Seperator Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans|Ste24p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Miller JP (2005)
    Phenotypic Enhancement
    bait Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ERV25
  • YML012W
    		•  The BioGRID Database Seperator Erv25p|Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family involved in endoplasmic reticulum to Golgi transport; protein coding
    Gene Ontology: [View List]
    PCA
    bait/hit Tarassov K (2008)
    Phenotypic Enhancement
    bait Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PMT1
  • YDL095W
    		•  The BioGRID Database Seperator Pmt1p|Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt2p, can instead interact with Pmt3p in some conditions; target for new antifungals; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Krogan NJ (2006)
    Phenotypic Enhancement
    bait/hit Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DIE2
  • ALG10
  • YGR227W
    		•  The BioGRID Database Seperator Die2p|Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER, functions in the pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation, has a role in regulation of ITR1 and INO1; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Burda P (1998)
    Phenotypic Enhancement
    bait/hit Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ALG9
  • YNL219C
    		•  The BioGRID Database Seperator Alg9p|Mannosyltransferase, involved in N-linked glycosylation; catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides; mutation of the human ortholog causes type 1 congenital disorders of glycosylation; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Burda P (1996)
    Phenotypic Enhancement
    bait/hit Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     WBP1
  • YEL002C
    		•  The BioGRID Database Seperator Beta subunit of the oligosaccharyl transferase (OST) glycoprotein complex; required for N-linked glycosylation of proteins in the endoplasmic reticulum|Wbp1p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Yan A (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SBH2
  • SEB2
  • YER019C-A
    		•  The BioGRID Database Seperator Sbh2p|Ssh1p-Sss1p-Sbh2p complex component, involved in protein translocation into the endoplasmic reticulum; homologous to Sbh1p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Yan A (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TFP3
  • CLS9
  • VMA11
  • YPL234C
    		•  The BioGRID Database Seperator Tfp3p|Vacuolar ATPase V0 domain subunit c', involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC63
  • PTL1
  • YOR254C
    		•  The BioGRID Database Seperator Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER|Sec63p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GPI2
  • GCR4
  • YPL076W
    		•  The BioGRID Database Seperator Gpi2p|Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     COP1
  • RET1
  • SEC33
  • SOO1
  • YDL145C
    		•  The BioGRID Database Seperator Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secretory pathway|Cop1p; protein coding
    Gene Ontology: [View List]
    Protein-peptide
    hit Letourneur F (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC61
  • YLR378C
    		•  The BioGRID Database Seperator Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER|Sec61p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait Chavan M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ORM2
  • YLR350W
    		•  The BioGRID Database Seperator Evolutionarily conserved protein with similarity to Orm1p, required for resistance to agents that induce the unfolded protein response; human ortholog is located in the endoplasmic reticulum|Orm2p; protein coding
    Gene Ontology: [View List]
    PCA
    bait/hit Tarassov K (2008)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TPO1
  • YLL028W
    		•  The BioGRID Database Seperator Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane|Tpo1p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VAN1
  • LDB13
  • VRG7
  • VRG8
  • YML115C
    		•  The BioGRID Database Seperator Component of the mannan polymerase I, which contains Van1p and Mnn9p and is involved in the first steps of mannan synthesis; mutants are vanadate-resistant|Van1p; protein coding
    Gene Ontology: [View List]