| Name |
Aliases |
 |
Description |
|
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| SPE4 |
YLR146C |
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Spe4p|Spermine synthase, required for the biosynthesis of spermine and also involved in biosynthesis of pantothenic acid; protein coding
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| CDC14 |
OAF3YFR028C |
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Cdc14p|Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit; protein coding
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| HRD1 |
DER3YOL013C |
|
Hrd1p|Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger; protein coding
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| HAP2 |
YGL237C |
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Hap2p|Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA binding; protein coding
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| HOS1 |
YPR068C |
|
Hos1p|Putative class I histone deacetylase (HDAC) with sequence similarity to Hda1p, Rpd3p, Hos2p, and Hos3p; deletion results in increased histone acetylation at rDNA repeats; interacts with the Tup1p-Ssn6p corepressor complex; protein coding
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| RTT109 |
KIM2REM50YLL002W |
|
Histone acetyltransferase critical for cell survival in the presence of DNA damage during S phase, acetylates H3-K56; plays a role in regulation of Ty1 transposition|Rtt109p; protein coding
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| HSP82 |
HSP90YPL240C |
|
Hsp82p|Hsp90 chaperone required for pheromone signaling and negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding and nucleotide addition; interacts with Cns1p, Cpr6p, Cpr7p, Sti1p; protein coding
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| FMS1 |
YMR020W |
|
Fms1p|Polyamine oxidase, converts spermine to spermidine, which is required for the essential hypusination modification of translation factor eIF-5A; also involved in pantothenic acid biosynthesis; protein coding
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| SEC14 |
PIT1YMR079W |
|
Phosphatidylinositol/phosphatidylcholine transfer protein involved in coordinate regulation of PtdIns and PtdCho metabolism, products of which are regulators in Golgi to plasma membrane transport; functionally homologous to mammalian PITPs|Sec14p; protein coding
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| KES1 |
LPI3OSH4BSR3YPL145C |
|
Kes1p|Member of the oxysterol binding protein family, which includes seven yeast homologs; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex; protein coding
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