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BioGRID | Network Layout for TAF14 for Saccharomyces cerevisiae
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TAF14

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: ANC1, SWP29, TAF30, TFG3, YPL129W
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes, involved in RNA polymerase II transcription initiation and in chromatin modification; contains a YEATS domain|Taf14p; protein coding
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [GeneDB]  [Germ Online]  [SGD]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 13 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with TAF14

TAF14 was identified with 208 protein interactions and 134 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code
Role Source [Interactions]
The BioGRID Database Seperator
 TFG1
  • RAP74
  • SSU71
  • YGR186W
    		•  The BioGRID Database Seperator TFIIF (Transcription Factor II) largest subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP74|Tfg1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Krogan NJ (2004) [890]
    hit Sanders SL (2002) [483]
    bait/hit Krogan NJ (2002) [90]
    hit Krogan NJ (2006) [7079]
    bait Collins SR (2007) [9064]
    Affinity Capture-Western
    bait Rani PG (2004) [10]
    bait Kabani M (2005) [12]
    Two-hybrid
    hit Kabani M (2005) [12]
    Reconstituted Complex
    hit Kabani M (2005) [12]
    Co-purification
    bait Wade PA (1996) [24]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SPT15
  • BTF1
  • TBP1
  • YER148W
    		•  The BioGRID Database Seperator Spt15p|TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    bait/hit Sanders SL (2000) [94]
    bait Krogan NJ (2006) [7079]
    Affinity Capture-Western
    bait Sanders SL (2000) [94]
    bait Poon D (1994) [13]
    bait Poon D (1995) [11]
    bait Moqtaderi Z (1998) [4]
    bait Klebanow ER (1996) [13]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TFG2
  • YGR005C
    		•  The BioGRID Database Seperator TFIIF (Transcription Factor II) middle subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP30|Tfg2p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    hit Krogan NJ (2002) [90]
    hit Krogan NJ (2006) [7079]
    bait Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Affinity Capture-Western
    bait Chung WH (2003) [9]
    Co-purification
    bait Wade PA (1996) [6]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     INO80
  • YGL150C
    		•  The BioGRID Database Seperator ATPase that forms a large complex, containing actin and several actin-related proteins, that has chromatin remodeling activity and 3' to 5' DNA helicase activity in vitro; shows similarity to the Snf2p family of ATPases|Ino80p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    bait Mizuguchi G (2004) [36]
    bait Morrison AJ (2004) [73]
    bait Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Two-hybrid
    hit Kabani M (2005) [12]
    Affinity Capture-Western
    bait Kabani M (2005) [12]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF1
  • TAF130
  • TAF145
  • YGR274C
    		•  The BioGRID Database Seperator TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation, has histone acetyltransferase activity, involved in promoter binding and G1/S progression|Taf1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    bait/hit Sanders SL (2000) [94]
    Affinity Capture-Western
    bait Mencia M (2001) [7]
    bait Bai Y (1997) [6]
    bait Garbett KA (2007) [15]
    Co-purification
    bait Sanders SL (2002) [14]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF2
  • TAF150
  • TSM1
  • YCR042C
    		•  The BioGRID Database Seperator TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation|Taf2p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    bait/hit Sanders SL (2002) [483]
    bait Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Two-hybrid
    hit Kabani M (2005) [12]
    Affinity Capture-Western
    bait Kabani M (2005) [12]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SAS3
  • YBL052C
    		•  The BioGRID Database Seperator Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality|Sas3p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Affinity Capture-Western
    bait John S (2000) [4]
    bait Kabani M (2005) [12]
    Two-hybrid
    hit Kabani M (2005) [12]
    Co-purification
    bait Howe L (2002) [5]
    bait John S (2000) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPB2
  • RPB150
  • RPO22
  • SIT2
  • YOR151C
    		•  The BioGRID Database Seperator RNA polymerase II second largest subunit B150, part of central core; similar to bacterial beta subunit|Rpb2p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    hit Krogan NJ (2002) [90]
    hit Krogan NJ (2006) [7079]
    bait Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNF6
  • YHL025W
    		•  The BioGRID Database Seperator Snf6p|Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Gavin AC (2006) [7592]
    Affinity Capture-Western
    bait Neely KE (2002) [14]
    bait/hit Cairns BR (1996) [17]
    bait Treich I (1995) [23]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SWI3
  • TYE2
  • YJL176C
    		•  The BioGRID Database Seperator Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2|Swi3p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Krogan NJ (2006) [7079]
    bait Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Affinity Capture-Western
    hit Cairns BR (1996) [17]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPO21
  • RPB1
  • RPB220
  • SUA8
  • YDL140C
    		•  The BioGRID Database Seperator RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime|Rpo21p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Krogan NJ (2004) [890]
    bait/hit Krogan NJ (2002) [90]
    hit Sanders SL (2002) [483]
    hit Krogan NJ (2006) [7079]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPB5
  • YBR154C
    		•  The BioGRID Database Seperator RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts DNA and affects transactivation|Rpb5p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Krogan NJ (2004) [890]
    hit Sanders SL (2002) [483]
    bait Krogan NJ (2006) [7079]
    bait Collins SR (2007) [9064]
    PCA
    bait Tarassov K (2008) [2616]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPB9
  • SHI1
  • SSU73
  • YGL070C
    		•  The BioGRID Database Seperator RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site; involved in telomere maintenance|Rpb9p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    hit Sanders SL (2002) [483]
    bait Krogan NJ (2006) [7079]
    bait Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARP4
  • ACT3
  • YJL081C
    		•  The BioGRID Database Seperator Arp4p|Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Downs JA (2004) [29]
    bait Krogan NJ (2006) [7079]
    bait Collins SR (2007) [9064]
    Synthetic Lethality
    bait Lin YY (2008) [2594]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARP9
  • SWP59
  • RSC12
  • YMR033W
    		•  The BioGRID Database Seperator Arp9p|Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Affinity Capture-Western
    hit Cairns BR (1996) [17]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF8
  • TAF65
  • YML114C
    		•  The BioGRID Database Seperator TFIID subunit (65 kDa), involved in RNA polymerase II transcription initiation|Taf8p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    bait Krogan NJ (2006) [7079]
    bait Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IES5
  • YER092W
    		•  The BioGRID Database Seperator Ies5p|Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARP8
  • YOR141C
    		•  The BioGRID Database Seperator Arp8p|Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Collins SR (2007) [9064]
    bait/hit Morrison AJ (2004) [73]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RVB2
  • TIH2
  • TIP49
  • TIP49B
  • YPL235W
    		•  The BioGRID Database Seperator Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family|Rvb2p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    hit Krogan NJ (2006) [7079]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPO26
  • RPB6
  • YPR187W
    		•  The BioGRID Database Seperator RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III; part of central core; similar to bacterial omega subunit|Rpo26p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    hit Krogan NJ (2006) [7079]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPB4
  • CTF15
  • YJL140W
    		•  The BioGRID Database Seperator RNA polymerase II subunit B32; forms two subunit dissociable complex with Rpb7p; dispensable under some environmental conditions; involved in export of mRNA to cytoplasm under stress conditions; involved in telomere maintenance|Rpb4p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    hit Krogan NJ (2006) [7079]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF13
  • FUN81
  • TAF19
  • YML098W
    		•  The BioGRID Database Seperator TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors|Taf13p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    bait Auty R (2004) [19]
    PCA
    bait Tarassov K (2008) [2616]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNF2
  • GAM1
  • HAF1
  • SWI2
  • YOR290C
    		•  The BioGRID Database Seperator Catalytic subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p|Snf2p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Affinity Capture-Western
    hit Cairns BR (1996) [17]
    Co-purification
    bait Smith CL (2003) [10]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARP5
  • YNL059C
    		•  The BioGRID Database Seperator Arp5p|Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRB4
  • MED17
  • YER022W
    		•  The BioGRID Database Seperator Srb4p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Co-purification
    bait Kim YJ (1994) [8]
    bait Takagi Y (2006) [28]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNF5
  • HAF4
  • SWI10
  • TYE4
  • YBR289W
    		•  The BioGRID Database Seperator Snf5p|Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf6p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Affinity Capture-Western
    hit Cairns BR (1996) [17]
    Two-hybrid
    hit Yu H (2008) [1778]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPB3
  • YIL021W
    		•  The BioGRID Database Seperator RNA polymerase II third largest subunit B44, part of central core; similar to prokaryotic alpha subunit|Rpb3p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Krogan NJ (2006) [7079]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNF12
  • SWP73
  • YNR023W
    		•  The BioGRID Database Seperator 73 kDa subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; homolog of Rsc6p subunit of the RSC chromatin remodeling complex; deletion mutants are temperature-sensitive|Snf12p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Collins SR (2007) [9064]
    Affinity Capture-Western
    hit Cairns BR (1996) [17]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STH1
  • NPS1
  • YIL126W
    		•  The BioGRID Database Seperator ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; essential helicase-related protein homologous to Snf2p|Sth1p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Kabani M (2005) [12]
    Affinity Capture-Western
    bait Kabani M (2005) [12]
    Reconstituted Complex
    hit Kabani M (2005) [12]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAL11
  • ABE1
  • MED15
  • RAR3
  • YOL051W
    		•  The BioGRID Database Seperator Gal11p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Two-hybrid
    bait Lim MK (2007) [75]
    Reconstituted Complex
    hit Lim MK (2007) [75]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IES4
  • YOR189W
    		•  The BioGRID Database Seperator Component of the INO80 chromatiin remodeling complex and target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses|Ies4p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Krogan NJ (2006) [7079]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IES1
  • YFL013C
    		•  The BioGRID Database Seperator Ies1p|Subunit of the INO80 chromatin remodeling complex; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Collins SR (2007) [9064]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNF11
  • YDR073W
    		•  The BioGRID Database Seperator Snf11p|Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; interacts with a highly conserved 40-residue sequence of Snf2p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Affinity Capture-Western
    bait Treich I (1995) [23]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IES3
  • YLR052W
    		•  The BioGRID Database Seperator Ies3p|Subunit of the INO80 chromatin remodeling complex; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Collins SR (2007) [9064]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NHP10
  • HMO2
  • YDL002C
    		•  The BioGRID Database Seperator Nhp10p|Protein related to mammalian high mobility group proteins; likely component of the INO80 complex, which is an ATP-dependent chromatin-remodeling complex; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Collins SR (2007) [9064]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ACT1
  • ABY1
  • END7
  • YFL039C
    		•  The BioGRID Database Seperator Act1p|Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Collins SR (2007) [9064]
    Synthetic Haploinsufficiency
    bait Haarer B (2007) [201]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RVB1
  • TIH1
  • TIP48
  • TIP49A
  • YDR190C
    		•  The BioGRID Database Seperator Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family|Rvb1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPB8
  • YOR224C
    		•  The BioGRID Database Seperator RNA polymerase subunit ABC14.5, common to RNA polymerases I, II, and III|Rpb8p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPB7
  • YDR404C
    		•  The BioGRID Database Seperator RNA polymerase II subunit B16; forms two subunit dissociable complex with Rpb4p|Rpb7p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MOT1
  • BUR3
  • LPF4
  • YPL082C
    		•  The BioGRID Database Seperator Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA via its C-terminal ATPase activity, forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity|Mot1p; protein coding
    Gene Ontology: [View List]
    Co-localization
    hit Dasgupta A (2005) [2]
    Affinity Capture-MS
    bait/hit Arnett DR (2008) [91]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RTT102
  • YGR275W
    		•  The BioGRID Database Seperator Component of both the SWI/SNF and RSC chromatin remodeling complexes, suggested role in chromosome maintenance; possible weak regulator of Ty1 transposition|Rtt102p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Krogan NJ (2006) [7079]
    bait Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMT3
  • YDR510W
    		•  The BioGRID Database Seperator Smt3p|Ubiquitin-like protein of the SUMO family, conjugated to lysine residues of target proteins; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Panse VG (2004) [117]
    Two-hybrid
    bait/hit Yu H (2008) [1778]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARP7
  • SWP61
  • RSC11
  • YPR034W
    		•  The BioGRID Database Seperator Arp7p|Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Affinity Capture-Western
    hit Cairns BR (1996) [17]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF3
  • TAF47
  • YPL011C
    		•  The BioGRID Database Seperator TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation|Taf3p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    Two-hybrid
    bait Gangloff YG (2001) [11]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SWI1
  • ADR6
  • GAM3
  • LPA1
  • YPL016W
    		•  The BioGRID Database Seperator Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2|Swi1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Affinity Capture-Western
    hit Cairns BR (1996) [17]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPB11
  • YOL005C
    		•  The BioGRID Database Seperator RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit|Rpb11p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RGR1
  • MED14
  • YLR071C
    		•  The BioGRID Database Seperator Rgr1p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for glucose repression, HO repression, RME1 repression and sporulation; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Affinity Capture-Western
    bait Lee YC (1999) [19]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YAF9
  • YNL107W
    		•  The BioGRID Database Seperator Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 complex, may function to antagonize silencing near telomeres; interacts directly with Swc4p, has homology to human leukemogenic protein AF9, contains a YEATS domain|Yaf9p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Zhang H (2004) [19]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    Synthetic Growth Defect
    bait Lin YY (2008) [2594]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIN4
  • BEL2
  • GAL22
  • MED16
  • YNL236W
    		•  The BioGRID Database Seperator Sin4p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; contributes to both postive and negative transcriptional regulation; dispensible for basal transcription; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NUT1
  • MED5
  • YGL151W
    		•  The BioGRID Database Seperator Component of the RNA polymerase II mediator complex, which is required for transcriptional activation and also has a role in basal transcription|Nut1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IES2
  • YNL215W
    		•  The BioGRID Database Seperator Ies2p|Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SAP185
  • YJL098W
    		•  The BioGRID Database Seperator Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap155p, and Sap190p|Sap185p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ho Y (2002) [3666]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MED1
  • YPR070W
    		•  The BioGRID Database Seperator Med1p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    Phenotypic Enhancement
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GCN4
  • AAS3
  • ARG9
  • YEL009C
    		•  The BioGRID Database Seperator Gcn4p|Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Neely KE (1999) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF12
  • TAF61
  • TAF68
  • YDR145W
    		•  The BioGRID Database Seperator Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A|Taf12p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YNG1
  • YOR29-15
  • YOR064C
    		•  The BioGRID Database Seperator Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3, has similarity to the human tumor suppressor ING1|Yng1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Nourani A (2003) [15]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MUS81
  • SLX3
  • YDR386W
    		•  The BioGRID Database Seperator Helix-hairpin-helix protein, involved in DNA repair and replication fork stability; functions as an endonuclease in complex with Mms4p; interacts with Rad54p|Mus81p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF5
  • TAF90
  • YBR198C
    		•  The BioGRID Database Seperator Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification|Taf5p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HAP4
  • YKL109W
    		•  The BioGRID Database Seperator Hap4p|Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Neely KE (1999) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MED4
  • YOR174W
    		•  The BioGRID Database Seperator Med4p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MCX1
  • YBR227C
    		•  The BioGRID Database Seperator Mcx1p|Mitochondrial ATP-binding protein, possibly a mitochondrial chaperone with non-proteolytic function; similar to bacterial ClpX proteins; protein coding
    Gene Ontology: [View List]
    PCA
    bait Tarassov K (2008) [2616]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YHR113W
  • YHR113W
    		•  The BioGRID Database Seperator Cytoplasmic aspartyl aminopeptidase; cleaves unblocked N-terminal acidic amino acid residues from peptide substrates; forms a 12 subunit homo-oligomeric complex; M18 metalloprotease family member; may interact with ribosomes|Yhr113wp; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Yu H (2008) [1778]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MED11
  • YMR112C
    		•  The BioGRID Database Seperator Med11p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential protein; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRE7
  • PRS3
  • YBL041W
    		•  The BioGRID Database Seperator 20S proteasome beta-type subunit|Pre7p; protein coding
    Gene Ontology: [View List]
    PCA
    bait Tarassov K (2008) [2616]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MED2
  • YDL005C
    		•  The BioGRID Database Seperator Med2p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MED6
  • YHR058C
    		•  The BioGRID Database Seperator Med6p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TFB4
  • YPR056W
    		•  The BioGRID Database Seperator Subunit of TFIIH complex, involved in transcription initiation, similar to 34 kDa subunit of human TFIIH; interacts with Ssl1p|Tfb4p; protein coding
    Gene Ontology: [View List]
    Co-purification
    bait Wade PA (1996) [24]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF6
  • TAF60
  • YGL112C
    		•  The BioGRID Database Seperator Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4|Taf6p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MED7
  • YOL135C
    		•  The BioGRID Database Seperator Med7p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF7
  • TAF67
  • YMR227C
    		•  The BioGRID Database Seperator TFIID subunit (67 kDa), involved in RNA polymerase II transcription initiation|Taf7p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PGD1
  • HRS1
  • MED3
  • YGL025C
    		•  The BioGRID Database Seperator Pgd1p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NUT2
  • MED10
  • YPR168W
    		•  The BioGRID Database Seperator Nut2p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for transcriptional activation and has a role in basal transcription; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSE2
  • MED9
  • YNR010W
    		•  The BioGRID Database Seperator Cse2p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; component of the Med9/10 module; required for regulation of RNA polymerase II activity; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ROX3
  • MED19
  • NUT3
  • SSN7
  • YBL093C
    		•  The BioGRID Database Seperator Rox3p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF4
  • MPT1
  • TAF48
  • TSG2
  • YMR005W
    		•  The BioGRID Database Seperator TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p substrate|Taf4p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IES6
  • YEL044W
    		•  The BioGRID Database Seperator Ies6p|Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF10
  • TAF23
  • TAF25
  • YDR167W
    		•  The BioGRID Database Seperator Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification|Taf10p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPC10
  • RPB12
  • YHR143W-A
    		•  The BioGRID Database Seperator RNA polymerase subunit, found in RNA polymerase complexes I, II, and III|Rpc10p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF9
  • TAF17
  • YMR236W
    		•  The BioGRID Database Seperator Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3|Taf9p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPB10
  • YOR210W
    		•  The BioGRID Database Seperator RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III|Rpb10p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF11
  • TAF40
  • YML015C
    		•  The BioGRID Database Seperator TFIID subunit (40 kDa), involved in RNA polymerase II transcription initiation, similar to histone H3 with atypical histone fold motif of Spt3-like transcription factors|Taf11p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MED8
  • YBR193C
    		•  The BioGRID Database Seperator Med8p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SPT7
  • GIT2
  • YBR081C
    		•  The BioGRID Database Seperator Spt7p|Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRB7
  • MED21
  • YDR308C
    		•  The BioGRID Database Seperator Srb7p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SPT5
  • YML010W
    		•  The BioGRID Database Seperator Protein that forms a complex with Spt4p and mediates both activation and inhibition of transcription elongation; Spt4p-Spt5p complex also plays a role in pre-mRNA processing|Spt5p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Lindstrom DL (2003) [113]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRB2
  • HRS2
  • MED20
  • YHR041C
    		•  The BioGRID Database Seperator Srb2p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRB6
  • MED22
  • YBR253W
    		•  The BioGRID Database Seperator Srb6p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRB5
  • MED18
  • YGR104C
    		•  The BioGRID Database Seperator Srb5p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in telomere maintenance; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RTT106
  • YNL206C
    		•  The BioGRID Database Seperator Protein with a role in regulation of Ty1 transposition|Rtt106p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ISW1
  • SGN2
  • YBR245C
    		•  The BioGRID Database Seperator Isw1p|Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation, and a complex with Ioc3p to repress transcription initiation; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBR1
  • PTR1
  • YGR184C
    		•  The BioGRID Database Seperator Ubiquitin-protein ligase (E3) that interacts with Rad6p/Ubc2p to ubiquitinate substrates of the N-end rule pathway; binds to the Rpn2p, Rpt1p, and Rpt6p proteins of the 19S particle of the 26S proteasome|Ubr1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IOC2
  • YLR095C
    		•  The BioGRID Database Seperator Ioc2p|Member of a complex (Isw1b) with Isw1p and Ioc4p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PHD finger motif; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SKI3
  • SKI5
  • YPR189W
    		•  The BioGRID Database Seperator Protein involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs; forms complex with Ski2p and Ski8p; required for repressing propagation of dsRNA viruses|Ski3p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SAS4
  • YDR181C
    		•  The BioGRID Database Seperator Sas4p|Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; required for the HAT activity of Sas2p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SKI8
  • REC103
  • YGL213C
    		•  The BioGRID Database Seperator Protein involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs as well as double-strand break formation during meiotic recombination; required for repressing propagation of dsRNA viruses|Ski8p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PSY2
  • YNL201C
    		•  The BioGRID Database Seperator Psy2p|Putative subunit of an evolutionarily conserved protein phosphatase complex containing the catalytic subunit Pph3p and the regulatory subunit Psy4p; required for cisplatin and oxaliplatin resistance; localizes to nucleus; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BRE5
  • YNR051C
    		•  The BioGRID Database Seperator Bre5p|Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that coregulates anterograde and retrograde transport between the endoplasmic reticulum and Golgi compartments; null is sensitive to brefeldin A; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ITC1
  • YGL133W
    		•  The BioGRID Database Seperator Component of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex, required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1|Itc1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSF1
  • YHR066W
    		•  The BioGRID Database Seperator Constituent of 66S pre-ribosomal particles, required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family|Ssf1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNU66
  • YOR308C
    		•  The BioGRID Database Seperator Component of the U4/U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; has homology to human SART-1 and to an S. pombe protein; snu66 null mutation confers cold-sensitivity but is not lethal at normal growth temperatures|Snu66p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BFA1
  • IBD1
  • YJR053W
    		•  The BioGRID Database Seperator Bfa1p|Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pathways that control exit from mitosis; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MFT1
  • MFT52
  • YML062C
    		•  The BioGRID Database Seperator Mft1p|Subunit of the THO complex, which is a nuclear complex comprised of Hpr1p, Mft1p, Rlr1p, and Thp2p, that is involved in transcription elongation and mitotic recombination; involved in telomere maintenance; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD54
  • XRS1
  • YGL163C
    		•  The BioGRID Database Seperator DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family|Rad54p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EAF3
  • YPR023C
    		•  The BioGRID Database Seperator Eaf3p|Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     REV7
  • YIL139C
    		•  The BioGRID Database Seperator Processivity subunit of DNA polymerase zeta, which is involved in DNA repair and translesion synthesis; required for mutagenesis induced by DNA damage|Rev7p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BMH1
  • APR6
  • YER177W
    		•  The BioGRID Database Seperator 14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling|Bmh1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTR9
  • CDP1
  • YOL145C
    		•  The BioGRID Database Seperator Component of the Paf1p complex, which is a large complex that binds to and modulates the activity of RNA polymerase II and is required for expression of a subset of genes, including cyclin genes; contains TPR repeats|Ctr9p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     WHI2
  • YOR043W
    		•  The BioGRID Database Seperator Protein required, with binding partner Psr1p, for full activation of the general stress response, possibly through Msn2p dephosphorylation; regulates growth during the diauxic shift; negative regulator of G1 cyclin expression|Whi2p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LGE1
  • YPL055C
    		•  The BioGRID Database Seperator Lge1p|Protein of unknown function; null mutant forms abnormally large cells; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ISW2
  • YOR304W
    		•  The BioGRID Database Seperator Isw2p|Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SET7
  • RMS1
  • YDR257C
    		•  The BioGRID Database Seperator Nuclear protein that contains a SET-domain, which have been shown to mediate methyltransferase activity in other proteins|Set7p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRA2
  • CCS1
  • GLC4
  • YOL081W
    		•  The BioGRID Database Seperator GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin|Ira2p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RTT107
  • ESC4
  • YHR154W
    		•  The BioGRID Database Seperator Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition|Rtt107p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KEX2
  • QDS1
  • SRB1
  • VMA45
  • YNL238W
    		•  The BioGRID Database Seperator Kex2p|Subtilisin-like protease (proprotein convertase), a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CLB1
  • SCB1
  • YGR108W
    		•  The BioGRID Database Seperator B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome|Clb1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPA34
  • YJL148W
    		•  The BioGRID Database Seperator RNA polymerase I subunit A34.5|Rpa34p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ESC8
  • YOL017W
    		•  The BioGRID Database Seperator Esc8p|Protein involved in telomeric and mating-type locus silencing, interacts with Sir2p and also interacts with the Gal11p, which is a component of the RNA pol II mediator complex; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YNG2
  • EAF4
  • NBN1
  • YHR090C
    		•  The BioGRID Database Seperator Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1|Yng2p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Lin YY (2008) [2594]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSN8
  • GIG3
  • NUT9
  • RYE2
  • YNL025C
    		•  The BioGRID Database Seperator Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression and telomere maintenance|Ssn8p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD53
  • LSD1
  • MEC2
  • SPK1
  • YPL153C
    		•  The BioGRID Database Seperator Protein kinase, required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication|Rad53p; protein coding
    Gene Ontology: [View List]
    Dosage Rescue
    bait Desany BA (1998) [28]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KAR9
  • YPL269W
    		•  The BioGRID Database Seperator Kar9p|Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplasmic microtubules, localizes at the shmoo tip in mating cells and at the tip of the growing bud in small-budded cells through anaphase; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GCN20
  • YFR009W
    		•  The BioGRID Database Seperator Gcn20p|Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HFI1
  • ADA1
  • SRM12
  • SUP110
  • YPL254W
    		•  The BioGRID Database Seperator Adaptor protein required for structural integrity of the SAGA complex, a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions|Hfi1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD61
  • YDR014W
    		•  The BioGRID Database Seperator Protein of unknown function; mutation confers radiation sensitivity|Rad61p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MEC1
  • ESR1
  • SAD3
  • YBR136W
    		•  The BioGRID Database Seperator Genome integrity checkpoint protein and PI kinase superfamily member; signal transducer required for cell cycle arrest and transcriptional responses prompted by damaged or unreplicated DNA; monitors and participates in meiotic recombination|Mec1p; protein coding
    Gene Ontology: [View List]
    Dosage Rescue
    bait Desany BA (1998) [28]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ACS2
  • YLR153C
    		•  The BioGRID Database Seperator Acetyl-coA synthetase isoform which, along with Acs1p, is the nuclear source of acetyl-coA for histone acetylation; mutants affect global transcription; required for growth on glucose; expressed under anaerobic conditions|Acs2p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    bait Lin YY (2008) [2594]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SWC4
  • EAF2
  • GOD1
  • YGR002C
    		•  The BioGRID Database Seperator Component of the Swr1p complex that incorporates Htz1p into chromatin; component of the NuA4 histone acetyltransferase complex|Swc4p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Lin YY (2008) [2594]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SDC1
  • CPS25
  • SAF19
  • YDR469W
    		•  The BioGRID Database Seperator Sdc1p|Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; has similarity to C. elegans Dpy-30; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ESA1
  • TAS1
  • YOR244W
    		•  The BioGRID Database Seperator Esa1p|Histone acetyltransferase catalytic subunit of the native multisubunit complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail; required for cell cycle progression; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Lin YY (2008) [2594]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EPL1
  • YFL024C
    		•  The BioGRID Database Seperator Component of NuA4, which is an essential histone H4/H2A acetyltransferase complex; homologous to Drosophila Enhancer of Polycomb|Epl1p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Lin YY (2008) [2594]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VID21
  • EAF1
  • YDR359C
    		•  The BioGRID Database Seperator Component of the NuA4 histone acetyltransferase complex|Eaf1p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    bait Lin YY (2008) [2594]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UFD4
  • YKL010C
    		•  The BioGRID Database Seperator Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins|Ufd4p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TOF2
  • YKR010C
    		•  The BioGRID Database Seperator Nonessential mitochondrial protein of unknown function with sequence similarity to Net1p; identified as a topoisomerase I (Top1p) binding protein; displays synthetic genetic interactions with TOP1 and HPR1|Tof2p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBC13
  • YDR092W
    		•  The BioGRID Database Seperator Ubc13p|Ubiquitin-conjugating enzyme involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MMR1
  • YLR190W
    		•  The BioGRID Database Seperator Mmr1p|Phosphorylated protein of the mitochondrial outer membrane, localizes only to mitochondria of the bud; interacts with Myo2p to mediate mitochondrial distribution to buds; mRNA is targeted to the bud via the transport system involving She2p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MDM39
  • GET1
  • YGL020C
    		•  The BioGRID Database Seperator Get1p|Subunit of the GET complex; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBP2
  • YOR124C
    		•  The BioGRID Database Seperator Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, cleaves at the C terminus of ubiquitin fusions; capable of cleaving polyubiquitin and possesses isopeptidase activity|Ubp2p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YGR071C
  • YGR071C
    		•  The BioGRID Database Seperator Putative protein of unknown function; deletion mutant has increased glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the nucleus|Ygr071cp; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC22
  • SLY2
  • TSL26
  • YLR268W
    		•  The BioGRID Database Seperator R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi complex; involved in anterograde and retrograde transport between the ER and Golgi; synaptobrevin homolog|Sec22p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RDH54
  • TID1
  • YBR073W
    		•  The BioGRID Database Seperator DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference|Rdh54p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YMR003W
  • YMR003W
    		•  The BioGRID Database Seperator Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondria; YMR003W is not an essential gene|Ymr003wp; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APC9
  • YLR102C
    		•  The BioGRID Database Seperator Apc9p|Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBC4
  • YBR082C
    		•  The BioGRID Database Seperator Ubc4p|Ubiquitin-conjugating enzyme (E2), mediates degradation of short-lived and abnormal proteins; interacts with E3-CaM in ubiquitinating calmodulin; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDA1
  • YER178W
    		•  The BioGRID Database Seperator E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA; phosphorylated; regulated by glucose|Pda1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD5
  • REV2
  • SNM2
  • YLR032W
    		•  The BioGRID Database Seperator Rad5p|Single-stranded DNA-dependent ATPase, involved in postreplication repair; contains RING finger domain; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIC1
  • SDB25
  • YLR079W
    		•  The BioGRID Database Seperator Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, preventing premature S phase and ensuring genomic integrity; phosphorylation targets Sic1p for SCF(CDC4)-dependent turnover; functional homolog of mammalian Kip1|Sic1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YKU80
  • HDF2
  • YMR106C
    		•  The BioGRID Database Seperator Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair|Yku80p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RIS1
  • DIS1
  • YOR191W
    		•  The BioGRID Database Seperator Member of the SWI/SNF family of DNA-dependent ATPases, plays a role in antagonizing silencing during mating-type switching, contains an N-terminal domain that interacts with Sir4p and a C-terminal SNF2 domain|Ris1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SWC3
  • SWC1
  • YAL011W
    		•  The BioGRID Database Seperator Protein of unknown function, component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for formation of nuclear-associated array of smooth endoplasmic reticulum known as karmellae|Swc3p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MRC1
  • YCL060C
  • YCL061C
    		•  The BioGRID Database Seperator Mrc1p|S-phase checkpoint protein found at replication forks, required for DNA replication; also required for Rad53p activation during DNA replication stress, where it forms a replication-pausing complex with Tof1p and is phosphorylated by Mec1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SAP30
  • YMR263W
    		•  The BioGRID Database Seperator Sap30p|Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is involved in silencing at telomeres, rDNA, and silent mating-type loci; involved in telomere maintenance; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBP6
  • YFR010W
    		•  The BioGRID Database Seperator Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; deletion causes hypersensitivity to cycloheximide and other toxic compounds|Ubp6p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LSM1
  • SPB8
  • YJL124C
    		•  The BioGRID Database Seperator Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs|Lsm1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SLX4
  • YLR135W
    		•  The BioGRID Database Seperator Slx4p|Subunit of a complex, with Slx1p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VPS64
  • FAR9
  • YDR200C
    		•  The BioGRID Database Seperator Cytoplasmic protein required for cytoplasm to vacuole targeting of proteins; forms a complex with Far3p, Far7p, Far10p, and Far11p that is involved in pheromone-induced cell cycle arrest; also localized to the endoplasmic reticulum membrane|Vps64p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RCO1
  • YMR075W
    		•  The BioGRID Database Seperator Essential subunit of the histone deacetylase Rpd3S complex; interacts with Eaf3p|Rco1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MNN10
  • BED1
  • REC41
  • SLC2
  • YDR245W
    		•  The BioGRID Database Seperator Mnn10p|Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family; protein codi