| Name |
Aliases |
 |
Description |
|
 |
| TFG1 |
RAP74SSU71YGR186W |
 |
TFIIF (Transcription Factor II) largest subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP74|Tfg1p; protein coding
|
|
 |
 |
 |
| SPT15 |
BTF1TBP1YER148W |
 |
Spt15p|TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability; protein coding
|
|
 |
 |
 |
| TFG2 |
YGR005C |
 |
TFIIF (Transcription Factor II) middle subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP30|Tfg2p; protein coding
|
|
 |
 |
 |
| INO80 |
YGL150C |
 |
ATPase that forms a large complex, containing actin and several actin-related proteins, that has chromatin remodeling activity and 3' to 5' DNA helicase activity in vitro; shows similarity to the Snf2p family of ATPases|Ino80p; protein coding
|
|
 |
 |
 |
| TAF1 |
TAF130TAF145YGR274C |
 |
TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation, has histone acetyltransferase activity, involved in promoter binding and G1/S progression|Taf1p; protein coding
|
|
 |
 |
 |
| TAF2 |
TAF150TSM1YCR042C |
 |
TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation|Taf2p; protein coding
|
|
 |
 |
 |
| SAS3 |
YBL052C |
 |
Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality|Sas3p; protein coding
|
|
 |
 |
 |
| RPB2 |
RPB150RPO22SIT2YOR151C |
 |
RNA polymerase II second largest subunit B150, part of central core; similar to bacterial beta subunit|Rpb2p; protein coding
|
|
 |
 |
 |
| SNF6 |
YHL025W |
 |
Snf6p|Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p; protein coding
|
|
 |
 |
 |
| SWI3 |
TYE2YJL176C |
 |
Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2|Swi3p; protein coding
|
|
 |
 |
 |
| RPO21 |
RPB1RPB220SUA8YDL140C |
 |
RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime|Rpo21p; protein coding
|
|
 |
 |
 |
| RPB5 |
YBR154C |
 |
RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts DNA and affects transactivation|Rpb5p; protein coding
|
|
 |
 |
 |
| RPB9 |
SHI1SSU73YGL070C |
 |
RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site; involved in telomere maintenance|Rpb9p; protein coding
|
|
 |
 |
 |
| ARP4 |
ACT3YJL081C |
 |
Arp4p|Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes; protein coding
|
|
 |
 |
 |
| ARP9 |
SWP59RSC12YMR033W |
 |
Arp9p|Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation; protein coding
|
|
 |
 |
 |
| TAF8 |
TAF65YML114C |
 |
TFIID subunit (65 kDa), involved in RNA polymerase II transcription initiation|Taf8p; protein coding
|
|
 |
 |
 |
| IES5 |
YER092W |
 |
Ies5p|Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions; protein coding
|
|
 |
 |
 |
| ARP8 |
YOR141C |
 |
Arp8p|Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes; protein coding
|
|
 |
 |
 |
| RVB2 |
TIH2TIP49TIP49BYPL235W |
 |
Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family|Rvb2p; protein coding
|
|
 |
 |
 |
| RPO26 |
RPB6YPR187W |
 |
RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III; part of central core; similar to bacterial omega subunit|Rpo26p; protein coding
|
|
 |
 |
 |
| RPB4 |
CTF15YJL140W |
 |
RNA polymerase II subunit B32; forms two subunit dissociable complex with Rpb7p; dispensable under some environmental conditions; involved in export of mRNA to cytoplasm under stress conditions; involved in telomere maintenance|Rpb4p; protein coding
|
|
 |
 |
 |
| TAF13 |
FUN81TAF19YML098W |
 |
TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors|Taf13p; protein coding
|
|
 |
 |
 |
| SNF12 |
SWP73YNR023W |
 |
73 kDa subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; homolog of Rsc6p subunit of the RSC chromatin remodeling complex; deletion mutants are temperature-sensitive|Snf12p; protein coding
|
|
 |
 |
 |
| ARP5 |
YNL059C |
 |
Arp5p|Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes; protein coding
|
|
 |
 |
 |
| SRB4 |
MED17YER022W |
 |
Srb4p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; protein coding
|
|
 |
 |
 |
| SNF2 |
GAM1HAF1SWI2YOR290C |
 |
Catalytic subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p|Snf2p; protein coding
|
|
 |
 |
 |
| RPB3 |
YIL021W |
 |
RNA polymerase II third largest subunit B44, part of central core; similar to prokaryotic alpha subunit|Rpb3p; protein coding
|
|
 |