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BioGRID | Network Layout for GAS1 for Saccharomyces cerevisiae
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GAS1

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: CWH52, GGP1, YMR307W
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Beta-1,3-glucanosyltransferase, required for cell wall assembly; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor|Gas1p; protein coding
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [GeneDB]  [Germ Online]  [SGD]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 7 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with GAS1

GAS1 was identified with 12 protein interactions and 224 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 CHS3
  • CAL1
  • CSD2
  • DIT101
  • YBR023C
    		•  The BioGRID Database Seperator Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan|Chs3p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait/hit Tong AH (2004)
    bait Valdivieso MH (2000)
    bait Popolo L (1997)
    bait/hit Lesage G (2004)
    bait/hit Lesage G (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CHS5
  • CAL3
  • YLR330W
    		•  The BioGRID Database Seperator Chs5p|Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in export of selected proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait/hit Tong AH (2004)
    hit Carotti C (2002)
    bait/hit Lesage G (2004)
    bait/hit Lesage G (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EMP24
  • BST2
  • YGL200C
    		•  The BioGRID Database Seperator Emp24p|Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Muñiz M (2000)
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YAL053W
  • FLC2
    		•  The BioGRID Database Seperator Flc2p|Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance; protein coding
    Gene Ontology: [View List]
    PCA
    bait Tarassov K (2008)
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RGP1
  • YDR137W
    		•  The BioGRID Database Seperator Rgp1p|Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    Phenotypic Enhancement
    hit Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SLG1
  • HCS77
  • WSC1
  • YOR008C
    		•  The BioGRID Database Seperator Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway involved in maintenance of cell wall integrity; involved in organization of the actin cytoskeleton; secretory pathway Wsc1p is required for the arrest of secretion response|Slg1p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Gualtieri T (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CWH41
  • GLS1
  • DER7
  • YGL027C
    		•  The BioGRID Database Seperator Cwh41p|Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein involved in assembly of cell wall beta 1,6 glucan and asparagine-linked protein glycosylation; also involved in ER protein quality control and sensing of ER stress; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait/hit Tong AH (2004)
    hit Lesage G (2004)
    Phenotypic Enhancement
    bait/hit Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     OPI3
  • PEM2
  • YJR073C
    		•  The BioGRID Database Seperator Opi3p|Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    Phenotypic Enhancement
    hit Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SLT2
  • BYC2
  • MPK1
  • SLK2
  • YHR030C
    		•  The BioGRID Database Seperator Serine/threonine MAP kinase involved in regulating the maintenance of cell wall integrity and progression through the cell cycle; regulated by the PKC1-mediated signaling pathway|Slt2p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Turchini A (2000)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCK1
  • LAS3
  • SAP3
  • SLK1
  • YJL095W
    		•  The BioGRID Database Seperator Bck1p|Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Turchini A (2000)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RIC1
  • YLR039C
    		•  The BioGRID Database Seperator Protein involved in retrograde transport to the cis-Golgi network; forms heterodimer with Rgp1p that acts as a GTP exchange factor for Ypt6p; involved in transcription of rRNA and ribosomal protein genes|Ric1p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait/hit Tong AH (2004)
    hit Lesage G (2004)
    Phenotypic Enhancement
    hit Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CNB1
  • CRV1
  • YCN2
  • YKL190W
    		•  The BioGRID Database Seperator Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is encoded by CNA1 and/or CMP1|Cnb1p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    bait Parsons AB (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ROT2
  • GLS2
  • YBR229C
    		•  The BioGRID Database Seperator Glucosidase II catalytic subunit required for normal cell wall synthesis; mutations in rot2 suppress tor2 mutations, and are synthetically lethal with rot1 mutations|Rot2p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait/hit Tong AH (2004)
    hit Lesage G (2004)
    Phenotypic Enhancement
    hit Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CHS7
  • YHR142W
    		•  The BioGRID Database Seperator Chs7p|Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p export from the ER; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Carotti C (2002)
    bait Lesage G (2005)
    Phenotypic Enhancement
    bait Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TOR2
  • DRR2
  • YKL203C
    		•  The BioGRID Database Seperator PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis|Tor2p; protein coding
    Gene Ontology: [View List]
    Co-fractionation
    bait Aronova S (2007)
    Synthetic Rescue
    bait Bickle M (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BST1
  • PER17
  • YFL025C
    		•  The BioGRID Database Seperator Bst1p|GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation, prevents production of vesicles with defective subunits, required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Fujita M (2006)
    Phenotypic Enhancement
    bait/hit Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HSP82
  • HSP90
  • YPL240C
    		•  The BioGRID Database Seperator Hsp82p|Hsp90 chaperone required for pheromone signaling and negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding and nucleotide addition; interacts with Cns1p, Cpr6p, Cpr7p, Sti1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Zhao R (2005)
    Synthetic Lethality
    bait Zhao R (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NAB6
  • YML117W
    		•  The BioGRID Database Seperator Nab6p|Putative RNA-binding protein, based on computational analysis of large-scale protein-protein interaction data; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RSC2
  • YLR357W
    		•  The BioGRID Database Seperator Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; involved in telomere maintenance|Rsc2p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ECM7
  • ZRG15
  • YLR443W
    		•  The BioGRID Database Seperator Ecm7p|Non-essential protein of unknown function; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIS2
  • HAL3
  • YKR072C
    		•  The BioGRID Database Seperator Negative regulatory subunit of the protein phosphatase 1 Ppz1p; involved in ion homeostasis and cell cycle progression|Sis2p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KEX2
  • QDS1
  • SRB1
  • VMA45
  • YNL238W
    		•  The BioGRID Database Seperator Kex2p|Subtilisin-like protease (proprotein convertase), a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Tomishige N (2003)
    Dosage Rescue
    bait/hit Tomishige N (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SKT5
  • CAL2
  • CHS4
  • CSD4
  • YBL061C
    		•  The BioGRID Database Seperator Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via interaction with Bni4p; has similarity to Shc1p, which activates Chs3p during sporulation|Skt5p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Carotti C (2002)
    bait Lesage G (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TGL3
  • YMR313C
    		•  The BioGRID Database Seperator Tgl3p|Triacylglycerol lipase of the lipid particle, responsible for all the TAG lipase activity of the lipid particle; contains the consensus sequence motif GXSXG, which is found in lipolytic enzymes; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ADH6
  • ADHVI
  • YMR318C
    		•  The BioGRID Database Seperator Adh6p|NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     QDR2
  • YIL121W
    		•  The BioGRID Database Seperator Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake|Qdr2p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SKG6
  • YHR149C
    		•  The BioGRID Database Seperator Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell periphery; potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p|Skg6p; protein coding
    Gene Ontology: [View List]
    Dosage Rescue
    hit Tomishige N (2005)
    Synthetic Rescue
    hit Tomishige N (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HAP5
  • YOR358W
    		•  The BioGRID Database Seperator Hap5p|Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; required for assembly and DNA binding activity of the complex; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PHO85
  • LDB15
  • YPL031C
    		•  The BioGRID Database Seperator Cyclin-dependent kinase, with ten cyclin partners; involved in environmental stress response; in phosphate-rich conditions, Pho85p-Pho80p complex phosphorylates Pho4p which in turn represses PHO5|Pho85p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAS5
  • YOL030W
    		•  The BioGRID Database Seperator 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall|Gas5p; protein coding
    Gene Ontology: [View List]
    Dosage Rescue
    hit Tomishige N (2005)
    Phenotypic Enhancement
    hit Schuldiner M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KRE1
  • YNL322C
    		•  The BioGRID Database Seperator Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer toxin membrane receptor|Kre1p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait/hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YPL041C
  • YPL041C
    		•  The BioGRID Database Seperator Protein of unknown function involved in maintenance of proper telomere length|Ypl041cp; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RLM1
  • YPL089C
    		•  The BioGRID Database Seperator MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p|Rlm1p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RIM21
  • PAL2
  • YNL294C
    		•  The BioGRID Database Seperator Component of the RIM101 pathway, has a role in cell wall construction and alkaline pH response; has similarity to A. nidulans PalH|Rim21p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YMR317W
  • YMR317W
    		•  The BioGRID Database Seperator Putative protein of unknown function with some similarity to sialidase from Trypanosoma; YMR317W is not an essential gene|Ymr317wp; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ROM2
  • YLR371W
    		•  The BioGRID Database Seperator GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEP|Rom2p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NBP2
  • YDR162C
    		•  The BioGRID Database Seperator Nbp2p|Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex, found in the nucleus and cytoplasm, contains an SH3 domain that binds Pbs2p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Tong AH (2004)
    hit Lesage G (2004)