| Name |
Aliases |
 |
Description |
| Evidence Code |
| Role |
Source [Interactions] |
|
|
|
| RPN3 |
SUN2YER021W |
|
Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control
|
|
|
|
|
| PET112 |
YBL080C |
|
Protein required for mitochondrial translation; mutation is functionally complemented by a Bacillus subtilis ortholog
|
|
|
|
|
| ARP4 |
ACT3YJL081C |
|
Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes
|
|
|
|
|
| JNM1 |
INS1PAC3YMR294W |
|
Component of the yeast dynactin complex, consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B
|
|
|
|
|
| SIN3 |
CPE1SDI1SDS16YOL004W |
|
Component of the Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity
|
|
|
|
|
| PHB1 |
YGR132C |
|
Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation
|
|
|
|
|
| SLX4 |
YLR135W |
|
Subunit of a complex, with Slx1p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p
|
|
|
|
|
| EAF5 |
YEL018W |
|
Esa1p-associated factor, non-essential subunit of the NuA4 acetyltransferase complex
|
|
|
|
|
| NPT1 |
YOR209C |
|
Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus
|
|
|
|
|
| BIM1 |
YEB1YER016W |
|
Microtubule-binding protein that together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally
|
|
|
|
|
| ARD1 |
YHR013C |
|
Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing
|
|
|
|
|
| SLX5 |
HEX3YDL013W |
|
Subunit of the Slx5-Slx8 substrate-specific ubiquitin ligase complex; stimulated by prior attachment of SUMO to the substrate
|
|
|
|
|
| NAT1 |
AAA1YDL040C |
|
Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing
|
|
|
|
|
| RAD18 |
YCR066W |
|
Protein involved in postreplication repair; binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; forms heterodimer with Rad6p; contains RING-finger motif
|
|
|
|
|
