| Name |
Aliases |
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Description |
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| CSG2 |
CLS2YBR036C |
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Csg2p|Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations; protein coding
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| ERG11 |
CYP51YHR007C |
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Erg11p|Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family; protein coding
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| GIM4 |
PFD2YEL003W |
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Gim4p|Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it; protein coding
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| BRE1 |
YDL074C |
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Bre1p|E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, recruitment of Rad6p to promoter chromatin and subsequent methylation of histone H3 (on K4 and K79), contains RING finger domain; protein coding
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| LGE1 |
YPL055C |
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Lge1p|Protein of unknown function; null mutant forms abnormally large cells; protein coding
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| BRE5 |
YNR051C |
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Bre5p|Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that coregulates anterograde and retrograde transport between the endoplasmic reticulum and Golgi compartments; null is sensitive to brefeldin A; protein coding
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| MDM39 |
GET1YGL020C |
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Get1p|Subunit of the GET complex; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance; protein coding
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| RIC1 |
YLR039C |
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Protein involved in retrograde transport to the cis-Golgi network; forms heterodimer with Rgp1p that acts as a GTP exchange factor for Ypt6p; involved in transcription of rRNA and ribosomal protein genes|Ric1p; protein coding
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| GYP1 |
YOR29-21YOR070C |
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Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion|Gyp1p; protein coding
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| MSC7 |
YHR039C |
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Msc7p|Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids; protein coding
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| KRE27 |
YIL027C |
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Kre27p|Protein of unknown function; null mutant shows K1 killer toxin resistance; protein coding
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| ORM2 |
YLR350W |
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Evolutionarily conserved protein with similarity to Orm1p, required for resistance to agents that induce the unfolded protein response; human ortholog is located in the endoplasmic reticulum|Orm2p; protein coding
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| ERV29 |
YGR284C |
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Erv29p|Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo; protein coding
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| YCR043C |
YCR043C |
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Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi apparatus; YCR043C is not an essential gene|Ycr043cp; protein coding
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| SSH1 |
YBR283C |
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Ssh1p|Subunit of the Ssh1 translocon complex; Sec61p homolog involved in co-translational pathway of protein translocation; not essential; protein coding
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| ERP1 |
YAR002C-A |
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Erp1p|Protein that forms a heterotrimeric complex with Erp2p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles; protein coding
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| ERV25 |
YML012W |
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Erv25p|Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family involved in endoplasmic reticulum to Golgi transport; protein coding
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| YKL088W |
YKL088W |
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Predicted phosphopantothenoylcysteine decarboxylase, may be involved in coenzyme A biosynthesis; interacts with Sis2p and Vhs3p|Ykl088wp; protein coding
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| STC2 |
TGL5YOR081C |
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Tgl5p|Triacylglycerol lipase involved in TAG mobilization; localizes to lipid particles; potential Cdc28p substrate; protein coding
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| PHO88 |
YBR106W |
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Pho88p|Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations; protein coding
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| ALG5 |
YPL227C |
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Alg5p|UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum; protein coding
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| TRS33 |
YOR115C |
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One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic|Trs33p; protein coding
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| SSO2 |
YMR183C |
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Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p|Sso2p; protein coding
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| YJR088C |
YJR088C |
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Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum|Yjr088cp; protein coding
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| SFT2 |
YBL102W |
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Non-essential tetra-spanning membrane protein found mostly in the late Golgi, can suppress some sed5 alleles; may be part of the transport machinery, but precise function is unknown; similar to mammalian syntaxin 5|Sft2p; protein coding
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| SEC62 |
LPG14YPL094C |
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Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER|Sec62p; protein coding
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| SCT1 |
GAT2YBL011W |
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Glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase of the glycerolipid biosynthesis pathway, prefers 16-carbon fatty acids, similar to Gpt2p, gene is constitutively transcribed|Sct1p; protein coding
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| VAC8 |
YEB3YEL013W |
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Phosphorylated vacuolar membrane protein that interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions|Vac8p; protein coding
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| SSM4 |
DOA10KIS3YIL030C |
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Ssm4p|Ubiquitin-protein ligase of the ER/nuclear envelope, required for degradation of Alpha2p and other proteins containing a Deg1 degradation signal; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation; protein coding
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| SPT23 |
YKL020C |
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ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Mga2p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting|Spt23p; protein coding
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| TGL1 |
YKL5YKL140W |
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Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes|Tgl1p; protein coding
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| SWA2 |
AUX1BUD24YDR320C |
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Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles|Swa2p; protein coding
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| SHR5 |
ERF4YOL110W |
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Shr5p|Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization; protein coding
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| YIP5 |
YGL161C |
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Protein that interacts with Rab GTPases, localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport|Yip5p; protein coding
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| YNL190W |
YNL190W |
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Cell wall protein of unknown function; proposed role as a hydrophilin induced by osmotic stress; contains a putative GPI-attachment site|Ynl190wp; protein coding
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| SEC63 |
PTL1YOR254C |
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Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER|Sec63p; protein coding
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| SEC24 |
ANU1YIL109C |
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Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; involved in ER to Golgi transport, cargo selection and autophagy; required for the binding of the Sec13 complex to ER membranes; homologous to Lst1p and Lss1p|Sec24p; protein coding
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| YND1 |
YEJ5YER005W |
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Apyrase with wide substrate specificity, involved in preventing the inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates which are inhibitors of glycotransferases; partially redundant with Gda1p|Ynd1p; protein coding
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| SEC72 |
SEC67SIM2YLR292C |
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Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER|Sec72p; protein coding
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| SEC66 |
HSS1SEC71YBR171W |
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Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER|Sec66p; protein coding
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| TRS20 |
YBR254C |
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One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; mutations in the human homolog cause the spondyloepiphyseal dysplasia tarda (SEDL) disorder|Trs20p; protein coding
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| SGM1 |
YJR134C |
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Protein of unknown function, required for wild-type growth rate on galactose and mannose; localizes to COPI coated vesicles and the Golgi apparatus|Sgm1p; protein coding
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