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BioGRID | Network Layout for CUS1 for Saccharomyces cerevisiae
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CUS1

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: YMR240C
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Protein required for assembly of U2 snRNP into the spliceosome, forms a complex with Hsh49p and Hsh155p
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [UniprotKB] | [SGD] | [Entrez Gene] | [GeneDB]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 7 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with CUS1

CUS1 was identified with 99 protein interactions and 7 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code
Role Source [Interactions]
The BioGRID Database Seperator
 HSH49
  • YOR319W
    		•  The BioGRID Database Seperator U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM)
    Gene Ontology: [View List]
    Two-hybrid
    hit Pauling MH (2000) [3]
    bait Igel H (1998) [2]
    bait/hit Fromont-Racine M (1997) [167]
    bait/hit Wang Q (2005) [32]
    Reconstituted Complex
    bait Pauling MH (2000) [3]
    Affinity Capture-Western
    hit Igel H (1998) [2]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    hit Wang Q (2005) [32]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RSE1
  • YML049C
    		•  The BioGRID Database Seperator Protein involved in pre-mRNA splicing; component of the pre-spliceosome; associates with U2 snRNA; involved in ER to Golgi transport
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    bait Dziembowski A (2004) [7]
    hit Krogan NJ (2006) [7079]
    hit Gavin AC (2006) [7592]
    hit Wang Q (2005) [32]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HSH155
  • YMR288W
    		•  The BioGRID Database Seperator U2-snRNP associated splicing factor that forms extensive associations with the branch site-3' splice site-3' exon region upon prespliceosome formation; similarity to the mammalian U2 snRNP-associated splicing factor SAP155
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    hit Krogan NJ (2006) [7079]
    hit Gavin AC (2006) [7592]
    hit Wang Q (2005) [32]
    hit Collins SR (2007) [9064]
    Affinity Capture-Western
    hit Pauling MH (2000) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LEA1
  • YPL213W
    		•  The BioGRID Database Seperator Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically interacts with Msl1p; invovled in telomere maintenance; putative homolog of human U2A' snRNP protein
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    hit Krogan NJ (2006) [7079]
    bait/hit Gavin AC (2006) [7592]
    bait Tardiff DF (2006) [40]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRP11
  • RNA11
  • YDL043C
    		•  The BioGRID Database Seperator Subunit of the SF3a splicing factor complex, required for spliceosome assembly
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    bait Krogan NJ (2006) [7079]
    hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Dosage Rescue
    bait Wells SE (1996) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMB1
  • YER029C
    		•  The BioGRID Database Seperator Core Sm protein Sm B; part of heteroheptameric complex (with Smd1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm B and Sm B'
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    bait Krogan NJ (2006) [7079]
    bait/hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CLF1
  • SYF3
  • NTC77
  • YLR117C
    		•  The BioGRID Database Seperator Essential splicesome assembly factor; contains multiple tetratricopeptide repeat (TPR) protein-binding motifs and interacts specifically with many spliceosome components, may serve as a scaffold during splicesome assembly
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Two-hybrid
    hit Wang Q (2005) [32]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMD3
  • SLT16
  • YLR147C
    		•  The BioGRID Database Seperator Core Sm protein Sm D3; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D3
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    hit Krogan NJ (2006) [7079]
    hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRP21
  • SPP91
  • YJL203W
    		•  The BioGRID Database Seperator Subunit of the SF3a splicing factor complex, required for spliceosome assembly
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    bait Krogan NJ (2006) [7079]
    bait/hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRP9
  • YDL030W
    		•  The BioGRID Database Seperator Subunit of the SF3a splicing factor complex, required for spliceosome assembly; acts after the formation of the U1 snRNP-pre-mRNA complex
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRP19
  • PSO4
  • YLL036C
    		•  The BioGRID Database Seperator Splicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiquitin ligases
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ohi MD (2002) [179]
    bait Collins SR (2007) [9064]
    Co-purification
    bait Stevens SW (2002) [96]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRP46
  • NTC50
  • YPL151C
    		•  The BioGRID Database Seperator Splicing factor that is found in the Cef1p subcomplex of the spliceosome
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    hit Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BRR2
  • SNU246
  • SLT22
  • PRP44
  • YER172C
    		•  The BioGRID Database Seperator RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD
    Gene Ontology: [View List]
    Two-hybrid
    hit Fromont-Racine M (1997) [167]
    Affinity Capture-MS
    bait/hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STO1
  • CBP80
  • GCR3
  • CBC1
  • YMR125W
    		•  The BioGRID Database Seperator Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RDS3
  • YPR094W
    		•  The BioGRID Database Seperator Zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Wang Q (2003) [5]
    bait/hit Wang Q (2005) [32]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMD2
  • YLR275W
    		•  The BioGRID Database Seperator Core Sm protein Sm D2; part of heteroheptameric complex (with Smb1p, Smd1p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D2
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SPP381
  • YBR152W
    		•  The BioGRID Database Seperator mRNA splicing factor, component of U4/U6.U5 tri-snRNP; interacts genetically and physically with Prp38p
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    bait Gavin AC (2006) [7592]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRP8
  • SLT21
  • USA2
  • RNA8
  • YHR165C
    		•  The BioGRID Database Seperator Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing; mutations of human Prp8 cause retinitis pigmentosa
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMD1
  • SPP92
  • YGR074W
    		•  The BioGRID Database Seperator Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D1
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRP6
  • RNA6
  • TSM7269
  • YBR055C
    		•  The BioGRID Database Seperator Splicing factor, component of the U4/U6-U5 snRNP complex
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IST3
  • SNU17
  • YIR005W
    		•  The BioGRID Database Seperator Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Wang Q (2005) [32]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNU23
  • YDL098C
    		•  The BioGRID Database Seperator Component of U4/U6.U5 snRNP involved in mRNA splicing via spliceosome
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CUS1
  • YMR240C
    		•  The BioGRID Database Seperator Protein required for assembly of U2 snRNP into the spliceosome, forms a complex with Hsh49p and Hsh155p
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Wang Q (2005) [32]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MUD2
  • YKL074C
    		•  The BioGRID Database Seperator Protein involved in early pre-mRNA splicing; component of the pre-mRNA-U1 snRNP complex, the commitment complex; interacts with Msl5p/BBP splicing factor and Sub2p; similar to metazoan splicing factor U2AF65
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Wang Q (2005) [32]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNU66
  • YOR308C
    		•  The BioGRID Database Seperator Component of the U4/U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; has homology to human SART-1 and to an S. pombe protein; snu66 null mutation confers cold-sensitivity but is not lethal at normal growth temperatures
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DIB1
  • SNU16
  • YPR082C
    		•  The BioGRID Database Seperator 17-kDa component of the U4/U6aU5 tri-snRNP, plays an essential role in pre-mRNA splicing, orthologue of hDIM1, the human U5-specific 15-kDa protein
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRP4
  • RNA4
  • YPR178W
    		•  The BioGRID Database Seperator Splicing factor, component of the U4/U6-U5 snRNP complex
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRP39
  • YML046W
    		•  The BioGRID Database Seperator U1 snRNP protein involved in splicing, contains multiple tetriatricopeptide repeats
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNU114
  • GIN10
  • YKL173W
    		•  The BioGRID Database Seperator GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; proposed to be involved in conformational changes of the spliceosome; similarity to ribosomal translocation factor EF-2
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRP31
  • YGR091W
    		•  The BioGRID Database Seperator Splicing factor, component of the U4/U6-U5 snRNP complex
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MSL1
  • YIB9
  • YIR009W
    		•  The BioGRID Database Seperator U2B component of U2 snRNP, involved in splicing, binds the U2 snRNA stem-loop IV in vitro; does not contain the conserved C-terminal RNA binding domain found in other family members
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRP3
  • RNA3
  • YDR473C
    		•  The BioGRID Database Seperator Splicing factor, component of the U4/U6-U5 snRNP complex
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BUD13
  • CWC26
  • YGL174W
    		•  The BioGRID Database Seperator Subunit of the RES complex, which is required for nuclear pre-mRNA retention and splicing; involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAB1
  • YER165W
    		•  The BioGRID Database Seperator Poly(A) binding protein, part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2006) [7592]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CYC8
  • CRT8
  • SSN6
  • YBR112C
    		•  The BioGRID Database Seperator General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters
    Gene Ontology: [View List]
    Two-hybrid
    hit Fromont-Racine M (1997) [167]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SWI1
  • GAM3
  • LPA1
  • ADR6
  • YPL016W
    		•  The BioGRID Database Seperator Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2
    Gene Ontology: [View List]
    Two-hybrid
    hit Fromont-Racine M (1997) [167]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNT309
  • NTC25
  • YPR101W
    		•  The BioGRID Database Seperator component of NineTeen complex (NTC) containing Prp19p involved in mRNA splicing, interacts physically and genetically with Prp19p
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ohi MD (2002) [179]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMX2
  • SNP2
  • YFL018W-A
  • YFL017W-A
    		•  The BioGRID Database Seperator Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx3p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm G
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMX3
  • YPR182W
    		•  The BioGRID Database Seperator Core Sm protein Sm F; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm F
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MIG1
  • TDS22
  • SSN1
  • CAT4
  • YGL035C
    		•  The BioGRID Database Seperator Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase
    Gene Ontology: [View List]
    Two-hybrid
    hit Fromont-Racine M (1997) [167]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     XDJ1
  • YLR090W
    		•  The BioGRID Database Seperator Putative chaperone, homolog of E. coli DnaJ, closely related to Ydj1p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
    Gene Ontology: [View List]
    Two-hybrid
    hit Fromont-Racine M (1997) [167]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CRN1
  • YLR429W
    		•  The BioGRID Database Seperator Coronin, cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regulate its activity
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CWC21
  • YDR482C
    		•  The BioGRID Database Seperator Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; may bind RNA; has similarity to S. pombe Cwf21p
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STM1
  • MPT4
  • YLR150W
    		•  The BioGRID Database Seperator Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YOR093C
  • YOR093C
    		•  The BioGRID Database Seperator Putative protein of unknown function; deletion causes sensitivity to unfolded protein response-inducing agents
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YRA1
  • SHE11
  • YDR381W
    		•  The BioGRID Database Seperator Nuclear protein that binds to RNA and to Mex67p, required for export of poly(A)+ mRNA from the nucleus; member of the REF (RNA and export factor binding proteins) family; another family member, Yra2p, can substitute for Yra1p function
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CEF1
  • NTC85
  • YMR213W
    		•  The BioGRID Database Seperator Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb DNA binding motif necessary for cell viability but not for Prp19p association, evolutionarily conserved and homologous to S. pombe Cdc5p
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YDL089W
  • YDL089W
    		•  The BioGRID Database Seperator Protein of unknown function; interacts with meiotic division protein Csm1p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery, potential Cdc28p substrate
    Gene Ontology: [View List]
    Positive Genetic
    hit Wilmes GM (2008) [6467]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JSN1
  • PUF1
  • YJR091C
    		•  The BioGRID Database Seperator Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; overexpression suppresses a tub2-150 mutation and causes increased sensitivity to benomyl in wild-type cells
    Gene Ontology: [View List]
    Positive Genetic
    bait Wilmes GM (2008) [6467]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MRT4
  • YKL009W
    		•  The BioGRID Database Seperator Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus
    Gene Ontology: [View List]
    Negative Genetic
    hit Wilmes GM (2008) [6467]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRP5
  • RNA5
  • YBR237W
    		•  The BioGRID Database Seperator RNA helicase in the DEAD-box family, necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA
    Gene Ontology: [View List]
    Dosage Rescue
    bait Wells SE (1996) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GTS1
  • FHT1
  • LSR1
  • YGL181W
    		•  The BioGRID Database Seperator Protein containing a zinc-finger in the N-terminus and a long Gln-rich region in the C-terminus; regulates ultradian rhythm, cell size, cell cycle, lifespan, sporulation, heat tolerance, and multidrug transport
    Gene Ontology: [View List]
    Synthetic Rescue
    bait Yan D (1996) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SLS1
  • YLR139C
    		•  The BioGRID Database Seperator Mitochondrial membrane protein that coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery
    Gene Ontology: [View List]
    Negative Genetic
    hit Wilmes GM (2008) [6467]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    terms and conditions - privacy policy - Osprey Network Visualization System
    BioGRID: A General Repository for Interaction Datasets.
    Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
    Nucleic Acids Res. Jan 1;34:D535-9.