| Name |
Aliases |
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Description |
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| TAF6 |
TAF60YGL112C |
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Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4|Taf6p; protein coding
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| TAF1 |
TAF130TAF145YGR274C |
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TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation, has histone acetyltransferase activity, involved in promoter binding and G1/S progression|Taf1p; protein coding
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| SPT15 |
BTF1TBP1YER148W |
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Spt15p|TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability; protein coding
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| TAF10 |
TAF23TAF25YDR167W |
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Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification|Taf10p; protein coding
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| TAF5 |
TAF90YBR198C |
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Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification|Taf5p; protein coding
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| TAF3 |
TAF47YPL011C |
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TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation|Taf3p; protein coding
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| TAF12 |
TAF61TAF68YDR145W |
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Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A|Taf12p; protein coding
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| TAF11 |
TAF40YML015C |
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TFIID subunit (40 kDa), involved in RNA polymerase II transcription initiation, similar to histone H3 with atypical histone fold motif of Spt3-like transcription factors|Taf11p; protein coding
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| TAF9 |
TAF17YMR236W |
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Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3|Taf9p; protein coding
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| TAF13 |
FUN81TAF19YML098W |
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TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors|Taf13p; protein coding
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| BDF1 |
YLR399C |
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Bdf1p|Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf2p; protein coding
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| TAF8 |
TAF65YML114C |
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TFIID subunit (65 kDa), involved in RNA polymerase II transcription initiation|Taf8p; protein coding
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| TAF4 |
MPT1TAF48TSG2YMR005W |
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TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p substrate|Taf4p; protein coding
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| RTG3 |
YBL103C |
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Basic helix-loop-helix-leucine zipper (bHLH/Zip) transcription factor that forms a complex with another bHLH/Zip protein, Rtg1p, to activate the retrograde (RTG) and TOR pathways|Rtg3p; protein coding
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| ASF1 |
CIA1YJL115W |
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Asf1p|Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; protein coding
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| SPT7 |
GIT2YBR081C |
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Spt7p|Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex; protein coding
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| GAL11 |
ABE1MED15RAR3YOL051W |
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Gal11p|Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors; protein coding
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| NDC1 |
YML031W |
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Ndc1p|Nuclear envelope protein with multiple putative transmembrane domains, required for nuclear pore complex assembly and spindle pole body duplication; required for meiosis II; protein coding
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| NGG1 |
ADA3SWI7YDR176W |
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Ngg1p|Transcriptional regulator involved in glucose repression of Gal4p-regulated genes; component of transcriptional adaptor and histone acetyltransferase complexes, the ADA complex, the SAGA complex, and the SLIK complex; protein coding
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| SPT8 |
YLR055C |
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Spt8p|Subunit of the SAGA transcriptional regulatory complex but not present in SAGA-like complex SLIK/SALSA, required for SAGA-mediated inhibition at some promoters; protein coding
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| GCN5 |
ADA4SWI9YGR252W |
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Gcn5p|Histone acetyltransferase, acetylates N-terminal lysines on histones H2B and H3; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily; protein coding
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| HFI1 |
ADA1SRM12SUP110YPL254W |
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Adaptor protein required for structural integrity of the SAGA complex, a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions|Hfi1p; protein coding
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| GAL4 |
GAL81YPL248C |
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DNA-binding transcription factor required for the activation of the GAL genes in response to galactose; repressed by Gal80p and activated by Gal3p|Gal4p; protein coding
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| TAF14 |
ANC1SWP29TAF30YPL129W |
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Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes, involved in RNA polymerase II transcription initiation and in chromatin modification; contains a YEATS domain|Taf14p; protein coding
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| TRA1 |
YHR099W |
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Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation|Tra1p; protein coding
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| CRZ1 |
HAL8TCN1YNL027W |
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Crz1p|Transcription factor that activates transcription of genes involved in stress response; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation; protein coding
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| TAF2 |
TAF150TSM1YCR042C |
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TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation|Taf2p; protein coding
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| SWI6 |
PSL8SDS11YLR182W |
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Swi6p|Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; localization regulated by phosphorylation; potential Cdc28p substrate; protein coding
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| RRP3 |
YHR065C |
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Protein involved in rRNA processing; required for maturation of the 35S primary transcript of pre-rRNA and for cleavage leading to mature 18S rRNA; homologous to eIF-4a, which is a DEAD box RNA-dependent ATPase with helicase activity|Rrp3p; protein coding
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| MCM1 |
FUN80YMR043W |
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Mcm1p|Transcription factor involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes; protein coding
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| MAD1 |
YGL086W |
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Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p|Mad1p; protein coding
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| MMS2 |
YGL087C |
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Mms2p|Protein involved in error-free postreplication DNA repair; forms a heteromeric complex with Ubc13p that has a ubiquitin-conjugating activity; cooperates with chromatin-associated RING finger proteins, Rad18p and Rad5p; protein coding
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| SDC1 |
CPS25SAF19YDR469W |
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Sdc1p|Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; has similarity to C. elegans Dpy-30; protein coding
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| ISW1 |
SGN2YBR245C |
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Isw1p|Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation, and a complex with Ioc3p to repress transcription initiation; protein coding
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| DOA1 |
UFD3ZZZ4YKL213C |
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Doa1p|WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase; protein coding
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| SWI3 |
TYE2YJL176C |
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Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2|Swi3p; protein coding
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