| Name |
Aliases |
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Description |
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| WBP1 |
YEL002C |
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Beta subunit of the oligosaccharyl transferase (OST) glycoprotein complex; required for N-linked glycosylation of proteins in the endoplasmic reticulum|Wbp1p; protein coding
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| OST1 |
NLT1YJL002C |
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Alpha subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins|Ost1p; protein coding
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| STT3 |
YGL022W |
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Stt3p|Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; forms a subcomplex with Ost3p and Ost4p and is directly involved in catalysis; protein coding
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| PKC1 |
CLY15HPO2STT1YBL105C |
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Pkc1p|Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC); protein coding
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| SSS1 |
YDR086C |
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Sss1p|Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) that forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p; protein coding
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| SHR3 |
APF1YDL212W |
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Endoplasmic reticulum packaging chaperone, required for incorporation of amino acid permeases into COPII coated vesicles for transport to the cell surface|Shr3p; protein coding
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| PHO88 |
YBR106W |
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Pho88p|Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations; protein coding
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| OST3 |
YOR085W |
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Gamma subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; Ost3p is important for N-glycosylation of a subset of proteins|Ost3p; protein coding
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| OST6 |
YML019W |
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Ost6p|Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; similar to and partially functionally redundant with Ost3p; protein coding
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| SEC61 |
YLR378C |
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Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER|Sec61p; protein coding
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| ALG5 |
YPL227C |
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Alg5p|UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum; protein coding
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| MSC7 |
YHR039C |
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Msc7p|Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids; protein coding
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| RER2 |
YBR002C |
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Cis-prenyltransferase involved in dolichol synthesis; participates in endoplasmic reticulum (ER) protein sorting|Rer2p; protein coding
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| ERG11 |
CYP51YHR007C |
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Erg11p|Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family; protein coding
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| ARF1 |
YDL192W |
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ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p|Arf1p; protein coding
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| KRE27 |
YIL027C |
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Kre27p|Protein of unknown function; null mutant shows K1 killer toxin resistance; protein coding
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| SSH1 |
YBR283C |
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Ssh1p|Subunit of the Ssh1 translocon complex; Sec61p homolog involved in co-translational pathway of protein translocation; not essential; protein coding
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| CPR4 |
CYP4SCC3YCR070WYCR069W |
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Cpr4p|Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway; protein coding
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| HNM1 |
YGL077C |
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Choline transporter (permease) that also controls the uptake of nitrogen mustard; expression is co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol|Hnm1p; protein coding
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| AYR1 |
YIL124W |
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Ayr1p|NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles, ER, and mitochondrial outer membrane; involved in phosphatidic acid biosynthesis; required for spore germination; capable of metabolizing steroid hormones; protein coding
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| FET3 |
YMR058W |
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Ferro-O2-oxidoreductase required for high-affinity iron uptake and involved in mediating resistance to copper ion toxicity, belongs to class of integral membrane multicopper oxidases|Fet3p; protein coding
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| SPC2 |
SPY1YML055W |
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Spc2p|Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC25; protein coding
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| PPZ1 |
YML016C |
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Ppz1p|Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance; protein coding
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| CPT1 |
YNL130C |
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Cholinephosphotransferase, required for phosphatidylcholine biosynthesis and for inositol-dependent regulation of EPT1 transcription|Cpt1p; protein coding
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| UIP4 |
YPL186C |
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Protein that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates; detected in a phosphorylated state in the mitochondrial outer membrane; also detected in ER and nuclear envelope|Uip4p; protein coding
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| DIP5 |
YPL265W |
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Dicarboxylic amino acid permease, mediates high-affinity and high-capacity transport of L-glutamate and L-aspartate; also a transporter for Gln, Asn, Ser, Ala, and Gly|Dip5p; protein coding
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| KRE1 |
YNL322C |
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Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer toxin membrane receptor|Kre1p; protein coding
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| ERV25 |
YML012W |
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Erv25p|Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family involved in endoplasmic reticulum to Golgi transport; protein coding
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| ORM2 |
YLR350W |
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Evolutionarily conserved protein with similarity to Orm1p, required for resistance to agents that induce the unfolded protein response; human ortholog is located in the endoplasmic reticulum|Orm2p; protein coding
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| ILM1 |
YJR118C |
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Ilm1p|Protein of unknown function; may be involved in mitochondrial DNA maintenance; required for slowed DNA synthesis-induced filamentous growth; protein coding
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| GTT1 |
YIR038C |
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ER associated glutathione S-transferase capable of homodimerization; expression induced during the diauxic shift and throughout stationary phase; functional overlap with Gtt2p, Grx1p, and Grx2p|Gtt1p; protein coding
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| DCW1 |
YKL046C |
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Dcw1p|Putative mannosidase, GPI-anchored membrane protein required for cell wall biosynthesis in bud formation;homologous to Dfg5p; protein coding
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| YKL088W |
YKL088W |
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Predicted phosphopantothenoylcysteine decarboxylase, may be involved in coenzyme A biosynthesis; interacts with Sis2p and Vhs3p|Ykl088wp; protein coding
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| CCW12 |
YLR110C |
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Ccw12p|Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor; protein coding
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| SIS2 |
HAL3YKR072C |
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Negative regulatory subunit of the protein phosphatase 1 Ppz1p; involved in ion homeostasis and cell cycle progression|Sis2p; protein coding
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| ERP1 |
YAR002C-A |
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Erp1p|Protein that forms a heterotrimeric complex with Erp2p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles; protein coding
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| SWP1 |
YMR149W |
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Delta subunit of the oligosaccharyl transferase glycoprotein complex, which is required for N-linked glycosylation of proteins in the endoplasmic reticulum|Swp1p; protein coding
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