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BioGRID | Network Layout for ASC1 for Saccharomyces cerevisiae
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ASC1

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: CPC2, YMR116C
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Asc1p|G-protein beta subunit and guanine nucleotide dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; represses Gcn4p in the absence of amino acid starvation; ncRNA
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [GeneDB]  [Germ Online]  [SGD]  [SGD]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 14 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with ASC1

ASC1 was identified with 62 protein interactions and 18 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 PRP43
  • YGL120C
    		•  The BioGRID Database Seperator Prp43p|RNA helicase in the DEAH-box family, functions in both RNA polymerase I and polymerase II transcript metabolism, involved in release of the lariat-intron from the spliceosome; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    hit Ho Y (2002)
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SCP160
  • YJL080C
    		•  The BioGRID Database Seperator Essential RNA-binding G protein effector of mating response pathway, mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins|Scp160p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    bait Gavin AC (2006)
    bait Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CHS5
  • CAL3
  • YLR330W
    		•  The BioGRID Database Seperator Chs5p|Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in export of selected proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2006)
    Synthetic Lethality
    bait Tong AH (2004)
    bait Lesage G (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMI1
  • KNR4
  • YGR229C
    		•  The BioGRID Database Seperator Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity|Smi1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Basmaji F (2006)
    Synthetic Lethality
    bait Tong AH (2004)
    bait Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TIF4631
  • YGR162W
    		•  The BioGRID Database Seperator Tif4631p|Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4632p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP22
  • YGR090W
    		•  The BioGRID Database Seperator Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data|Utp22p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KRI1
  • YNL308C
    		•  The BioGRID Database Seperator Essential nucleolar protein required for 40S ribosome biogenesis; physically and functionally interacts with Krr1p|Kri1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002)
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ZUO1
  • YGR285C
    		•  The BioGRID Database Seperator Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the Ssb proteins, as a chaperone for nascent polypeptide chains; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p|Zuo1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SKI3
  • SKI5
  • YPR189W
    		•  The BioGRID Database Seperator Protein involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs; forms complex with Ski2p and Ski8p; required for repressing propagation of dsRNA viruses|Ski3p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2006)
    hit Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NAT1
  • AAA1
  • YDL040C
    		•  The BioGRID Database Seperator Nat1p|Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CHS3
  • CAL1
  • CSD2
  • DIT101
  • YBR023C
    		•  The BioGRID Database Seperator Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan|Chs3p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Tong AH (2004)
    bait Lesage G (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GCN2
  • AAS1
  • YDR283C
    		•  The BioGRID Database Seperator Gcn2p|Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; protein coding
    Gene Ontology: [View List]
    Synthetic Rescue
    bait Hoffmann B (1999)
    Phenotypic Suppression
    hit Valerius O (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BUD14
  • YAR014C
    		•  The BioGRID Database Seperator Bud14p|Protein involved in bud-site selection, Bud14p-Glc7p complex functions as a cortical regulator of dynein; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RVB2
  • TIH2
  • TIP49
  • TIP49B
  • YPL235W
    		•  The BioGRID Database Seperator Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family|Rvb2p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS8A
  • YBL072C
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit; identical to Rps8Bp and has similarity to rat S8 ribosomal protein|Rps8ap; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL18A
  • RP28A
  • YOL120C
    		•  The BioGRID Database Seperator Protein component of the large (60S) ribosomal subunit, identical to Rpl18Bp and has similarity to rat L18 ribosomal protein; intron of RPL18A pre-mRNA forms stem-loop structures that are a target for Rnt1p cleavage leading to degradation|Rpl18ap; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LTE1
  • MSI2
  • YAL024C
    		•  The BioGRID Database Seperator Lte1p|Putative GDP/GTP exchange factor required for mitotic exit at low temperatures; acts as a guanine nucleotide exchange factor (GEF) for Tem1p, which is a key regulator of mitotic exit; physically associates with Ras2p-GTP; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Graumann J (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ENP1
  • MEG1
  • YBR247C
    		•  The BioGRID Database Seperator Enp1p|Protein associated with U3 and U14 snoRNAs, required for pre-rRNA processing and 40S ribosomal subunit synthesis; localized in the nucleus and concentrated in the nucleolus; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KIN3
  • FUN52
  • NPK1
  • YAR018C
    		•  The BioGRID Database Seperator Kin3p|Nonessential protein kinase with unknown cellular role; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMB1
  • YER029C
    		•  The BioGRID Database Seperator Core Sm protein Sm B; part of heteroheptameric complex (with Smd1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm B and Sm B'|Smb1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS9B
  • RPS13A
  • SUP46
  • YBR189W
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Ap and has similarity to E. coli S4 and rat S9 ribosomal proteins|Rps9bp; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPO31
  • RPC1
  • RPC160
  • YOR116C
    		•  The BioGRID Database Seperator RNA polymerase III subunit C160, part of core enzyme; similar to bacterial beta-prime subunit|Rpo31p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS22A
  • RPS24
  • YJL190C
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins|Rps22ap; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GPA2
  • SSP101
  • YER020W
    		•  The BioGRID Database Seperator Gpa2p|Nucleotide binding alpha subunit of the heterotrimeric G protein that interacts with the receptor Gpr1p, has signaling role in response to nutrients; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Zeller CE (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STE20
  • YHL007C
    		•  The BioGRID Database Seperator Signal transducing kinase of the PAK (p21-activated kinase) family, involved in pheromone response and pseudohyphal/invasive growth pathways, activated by Cdc42p; binds Ste4p at a GBB motif present in noncatalytic domains of PAK kinases|Ste20p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Zeller CE (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CYR1
  • CDC35
  • FIL1
  • HSR1
  • YJL005W
    		•  The BioGRID Database Seperator Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation|Cyr1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Zeller CE (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS7A
  • RPS30
  • YOR096W
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins|Rps7ap; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS22B
  • YLR367W
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins|Rps22bp; ncRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CHS6
  • CSD3
  • YJL099W
    		•  The BioGRID Database Seperator Chs6p|Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS5
  • YJR123W
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins|Rps5p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS4A
  • YJR145C
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein|Rps4ap; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS13
  • RPS13B
  • RPS13C
  • YDR064W
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S15 and rat S13 ribosomal proteins|Rps13p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HRR25
  • YPL204W
    		•  The BioGRID Database Seperator Hrr25p|Protein kinase involved in regulating diverse events including vesicular trafficking, DNA repair, and chromosome segregation; binds the CTD of RNA pol II; homolog of mammalian casein kinase 1delta (CK1delta); protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARD1
  • YHR013C
    		•  The BioGRID Database Seperator Ard1p|Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ENP2
  • YGR145W
    		•  The BioGRID Database Seperator Enp2p|Essential nucleolar protein of unknown function; contains WD repeats, interacts with Mpp10p and Bfr2p, and has homology to Spb1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NOB1
  • YOR29-07
  • YOR056C
    		•  The BioGRID Database Seperator Essential nuclear protein involved in proteasome maturation and synthesis of 40S ribosomal subunits; required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA|Nob1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KRR1
  • YCL059C
    		•  The BioGRID Database Seperator Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit|Krr1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIK1
  • NOP56
  • YLR197W
    		•  The BioGRID Database Seperator Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that direct 2'-O-methylation of pre-rRNA during its maturation; overexpression causes spindle orientation defects|Sik1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TMA22
  • YJR014W
    		•  The BioGRID Database Seperator Protein of unknown function that associates with ribosomes and has a putative RNA binding domain; interacts with Tma20p; has homology to human protein DRP1, which interacts with human Tma20p homolog MCT-1|Tma22p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSE1
  • LPG3
  • MSI3
  • YPL106C
    		•  The BioGRID Database Seperator ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded proteins; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm|Sse1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD3
  • REM1
  • YER171W
    		•  The BioGRID Database Seperator 5' to 3' DNA helicase, involved in nucleotide excision repair and transcription; subunit of RNA polymerase II transcription initiation factor TFIIH; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPD protein|Rad3p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRT1
  • CDC63
  • DNA26
  • YOR361C
    		•  The BioGRID Database Seperator Prt1p|Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait