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BioGRID | Network Layout for FAF1 for Saccharomyces cerevisiae
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FAF1

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: YIL019W
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Protein required for pre-rRNA processing and 40S ribosomal subunit assembly
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [UniprotKB] | [SGD] | [Entrez Gene] | [GeneDB]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 6 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with FAF1

FAF1 was identified with 45 protein interactions and 3 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code
Role Source [Interactions]
The BioGRID Database Seperator
 KRR1
  • YCL059C
    		•  The BioGRID Database Seperator Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit
    Gene Ontology: [View List]
    Two-hybrid
    bait Karkusiewicz I (2004) [1]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP30
  • YKR060W
    		•  The BioGRID Database Seperator Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BMS1
  • YPL217C
    		•  The BioGRID Database Seperator Essential conserved nucleolar GTP-binding protein required for synthesis of 40S ribosomal subunits and for processing of the 35S pre-rRNA at sites A0, A1, and A2; interacts with Rcl1p, has similarity to Tsr1p
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BFR2
  • YDR299W
    		•  The BioGRID Database Seperator Essential protein possibly involved in secretion; multicopy suppressor of sensitivity to Brefeldin A
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EMG1
  • NEP1
  • YLR186W
    		•  The BioGRID Database Seperator Protein required for the maturation of the 18S rRNA and for 40S ribosome production; associated with spindle/microtubules; nuclear localization depends on physical interaction with Nop14p; may bind snoRNAs
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KRE33
  • YNL132W
    		•  The BioGRID Database Seperator Essential protein of unknown function; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP22
  • YGR090W
    		•  The BioGRID Database Seperator Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NOC4
  • UTP19
  • YPR144C
    		•  The BioGRID Database Seperator Nucleolar protein, forms a complex with Nop14p that mediates maturation and nuclear export of 40S ribosomal subunits
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP20
  • YBL004W
    		•  The BioGRID Database Seperator Component of the small-subunit (SSU) processome, which is involved in the biogenesis of the 18S rRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP21
  • YLR409C
    		•  The BioGRID Database Seperator Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ENP1
  • MEG1
  • YBR247C
    		•  The BioGRID Database Seperator Protein associated with U3 and U14 snoRNAs, required for pre-rRNA processing and 40S ribosomal subunit synthesis; localized in the nucleus and concentrated in the nucleolus
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RCL1
  • YOL010W
    		•  The BioGRID Database Seperator RNA terminal phosphate cyclase-like protein involved in rRNA processing at sites A0, A1, and A2; does not possess detectable RNA cyclase activity
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS13
  • RPS13B
  • RPS13C
  • YDR064W
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S15 and rat S13 ribosomal proteins
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FCF1
  • UTP24
  • YDR339C
    		•  The BioGRID Database Seperator Essential nucleolar protein that is a component of the SSU (small subunit) processome involved in the pre-rRNA processing steps of 40S ribosomal subunit biogenesis; contains a PINc domain; copurifies with Faf1p
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FCF2
  • YLR051C
    		•  The BioGRID Database Seperator Essential nucleolar protein involved in the early steps of 35S rRNA processing; interacts with Faf1p; member of a transcriptionally co-regulated set of genes called the RRB regulon
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RRP14
  • YKL082C
    		•  The BioGRID Database Seperator Essential protein, constituent of 66S pre-ribosomal particles; interacts with proteins involved in ribosomal biogenesis and cell polarity; member of the SURF-6 family
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Yamada H (2007) [13]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS7A
  • RPS30
  • YOR096W
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS5
  • YJR123W
    		•  The BioGRID Database Seperator Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PNO1
  • RRP20
  • DIM2
  • YOR145C
    		•  The BioGRID Database Seperator Essential nucleolar protein required for pre-18S rRNA processing, interacts with Dim1p, an 18S rRNA dimethyltransferase, and also with Nob1p, which is involved in proteasome biogenesis; contains a KH domain
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LCP5
  • YER127W
    		•  The BioGRID Database Seperator Essential protein involved in maturation of 18S rRNA; depletion leads to inhibited pre-rRNA processing and reduced polysome levels; localizes primarily to the nucleolus
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS1A
  • RP10A
  • YLR441C
    		•  The BioGRID Database Seperator Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Bp and has similarity to rat S3a ribosomal protein
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NAN1
  • UTP17
  • YPL126W
    		•  The BioGRID Database Seperator U3 snoRNP protein, component of the small (ribosomal) subunit (SSU) processosome containing U3 snoRNA; required for the biogenesis of18S rRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP18
  • YJL069C
    		•  The BioGRID Database Seperator Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ECM16
  • DHR1
  • YMR128W
    		•  The BioGRID Database Seperator Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP, predominantly nucleolar in distribution, required for 18S rRNA synthesis
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RRP9
  • YPR137W
    		•  The BioGRID Database Seperator Protein involved in pre-rRNA processing, associated with U3 snRNP; component of small ribosomal subunit (SSU) processosome; ortholog of the human U3-55k protein
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PWP2
  • YCR058C
  • YCR055C
  • UTP1
  • YCR057C
    		•  The BioGRID Database Seperator Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NOP14
  • UTP2
  • YDL148C
    		•  The BioGRID Database Seperator Nucleolar protein, forms a complex with Noc4p that mediates maturation and nuclear export of 40S ribosomal subunits; also present in the small subunit processome complex, which is required for processing of pre-18S rRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IMP4
  • YNL075W
    		•  The BioGRID Database Seperator Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IMP3
  • YHR148W
    		•  The BioGRID Database Seperator Component of the SSU processome, which is required for pre-18S rRNA processing, essential protein that interacts with Mpp10p and mediates interactions of Imp4p and Mpp10p with U3 snoRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NOP1
  • LOT3
  • YDL014W
    		•  The BioGRID Database Seperator Nucleolar protein, component of the small subunit processome complex, which is required for processing of pre-18S rRNA; has similarity to mammalian fibrillarin
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOF1
  • YLL011W
    		•  The BioGRID Database Seperator Essential protein required for biogenesis of 40S (small) ribosomal subunit; has similarity to the beta subunit of trimeric G-proteins and the splicing factor Prp4p
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MPP10
  • YJR002W
    		•  The BioGRID Database Seperator Component of the SSU processome, which is required for pre-18S rRNA processing, interacts with and controls the stability of Imp3p and Imp4p, essential for viability; similar to human Mpp10p
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BUD21
  • YOR29-29
  • UTP16
  • YOR078W
    		•  The BioGRID Database Seperator Component of small ribosomal subunit (SSU) processosome that contains U3 snoRNA; originally isolated as bud-site selection mutant that displays a random budding pattern
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SAS10
  • UTP3
  • YDL153C
    		•  The BioGRID Database Seperator Component of the small (ribosomal) subunit (SSU) processosome required for pre-18S rRNa processing; essential nucleolar protein that, when overproduced, disrupts silencing
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP4
  • YDR324C
    		•  The BioGRID Database Seperator Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DIP2
  • UTP12
  • YLR129W
    		•  The BioGRID Database Seperator Nucleolar protein, specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP13
  • YLR222C
    		•  The BioGRID Database Seperator Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP15
  • YMR093W
    		•  The BioGRID Database Seperator Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP10
  • YJL109C
    		•  The BioGRID Database Seperator Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP11
  • YKL099C
    		•  The BioGRID Database Seperator Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP9
  • YHR196W
    		•  The BioGRID Database Seperator Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP7
  • KRE31
  • YER082C
    		•  The BioGRID Database Seperator Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP5
  • YDR398W
    		•  The BioGRID Database Seperator Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UTP8
  • YGR128C
    		•  The BioGRID Database Seperator Nucleolar protein required for export of tRNAs from the nucleus; also copurifies with the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rempola B (2006) [43]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JSN1
  • PUF1
  • YJR091C
    		•  The BioGRID Database Seperator Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; overexpression suppresses a tub2-150 mutation and causes increased sensitivity to benomyl in wild-type cells
    Gene Ontology: [View List]
    Positive Genetic
    bait Wilmes GM (2008) [6467]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MSM1
  • YGR171C
    		•  The BioGRID Database Seperator Mitochondrial methionyl-tRNA synthetase (MetRS), functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p
    Gene Ontology: [View List]
    Positive Genetic
    hit Wilmes GM (2008) [6467]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EAF6
  • YJR082C
    		•  The BioGRID Database Seperator Subunit of the NuA4 acetyltransferase complex that acetylates histone H4 and NuA3 acetyltransferase complex that acetylates histone H3
    Gene Ontology: [View List]
    Positive Genetic
    hit Wilmes GM (2008) [6467]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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