| Name |
Aliases |
 |
Description |
| Evidence Code |
| Role |
Source [Interactions] |
|
|
 |
| CBK1 |
YNL161W |
 |
Serine/threonine protein kinase that regulates cell morphogenesis pathways; involved in cell wall biosynthesis, apical growth, proper mating projection morphology, bipolar bud site selection in diploid cells, and cell separation
|
|
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| SSD1 |
CLA1MCS1SRK1YDR293C |
 |
Protein with a role in maintenance of cellular integrity, interacts with components of the TOR pathway; ssd1 mutant of a clinical S. cerevisiae strain displays elevated virulence
|
|
 |
 |
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| SUP45 |
SUP47SUP1SAL4YBR143C |
 |
Polypeptide release factor involved in translation termination; mutant form acts as a recessive omnipotent suppressor
|
|
 |
 |
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| SIM1 |
YIL123W |
 |
Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated
|
|
 |
 |
 |
| NBP35 |
YGL091C |
 |
Essential iron-sulfur cluster binding protein localized in the cytoplasm; forms a complex with Cfd1p that is involved in iron-sulfur protein assembly in the cytosol; similar to P-loop NTPases
|
|
 |
 |
 |
| LGE1 |
YPL055C |
 |
Protein of unknown function; null mutant forms abnormally large cells
|
|
 |
 |
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| SBP1 |
SSB1SSBR1YHL034C |
 |
Putative RNA binding protein; involved in translational repression and found in cytoplasmic P bodies; found associated with small nucleolar RNAs snR10 and snR11
|
|
 |
 |
 |
| VAC8 |
YEB3YEL013W |
 |
Phosphorylated vacuolar membrane protein that interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions
|
|
 |
 |
 |
| TAF12 |
TAF61TAF68YDR145W |
 |
Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A
|
|
 |
 |
 |
| KIC1 |
NRK1YHR102W |
 |
Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possibly through regulating 1,6-beta-glucan levels in the wall; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body
|
|
 |
 |
 |
| YRA1 |
SHE11YDR381W |
 |
Nuclear protein that binds to RNA and to Mex67p, required for export of poly(A)+ mRNA from the nucleus; member of the REF (RNA and export factor binding proteins) family; another family member, Yra2p, can substitute for Yra1p function
|
|
 |
 |
 |
| SNU56 |
MUD10YDR240C |
 |
Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; interacts with mRNA in commitment complex
|
|
 |
 |
 |
| HYM1 |
YKL189W |
 |
Component of the RAM signaling network that is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response
|
|
 |
 |
 |
| CRM1 |
KAP124XPO1YGR218W |
 |
Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits from the nucleus
|
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 |
 |
 |
| ACE2 |
YLR131C |
 |
Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters, localization is regulated by phosphorylation; potential Cdc28p substrate
|
|
 |
 |
 |
| GYP1 |
YOR29-21YOR070C |
 |
Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion
|
|
 |
 |
 |
| RAS2 |
CYR3CTN5TSL7YNL098C |
 |
GTP-binding protein that regulates the nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes
|
|
 |
 |
 |
| MOB2 |
YFL035CYFL035C-AYFL034C-B |
 |
Component of the RAM signaling network, localizes and activates the Ace2p in the daughter cell nucleus to direct daughter cell-specific transcription of several genes involved in cell separation; Mob1p-like protein
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