| Name |
Aliases |
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Description |
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| SRP101 |
YDR292C |
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Signal recognition particle (SRP) receptor - alpha subunit; contain GTPase domains; involved in SRP-dependent protein targeting; interacts with SRP102p|Srp101p; protein coding
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| EMP47 |
YFL048C |
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Emp47p|Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport; protein coding
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| CAN1 |
YEL063C |
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Can1p|Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance; protein coding
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| PMP2 |
YEL017C-A |
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Pmp2p|Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; nearly identical to PMP1; protein coding
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| EMP24 |
BST2YGL200C |
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Emp24p|Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport; protein coding
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| ERG25 |
YGR060W |
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C-4 methyl sterol oxidase, catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol|Erg25p; protein coding
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| MAL11 |
AGT1YGR289C |
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Mal11p|Maltose permease, inducible high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL1 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters; protein coding
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| TNA1 |
YGR260W |
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High affinity nicotinic acid plasma membrane permease, responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA)|Tna1p; protein coding
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| GPI8 |
YDR331W |
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ER membrane glycoprotein subunit of the glycosylphosphatidylinositol transamidase complex that adds glycosylphosphatidylinositol (GPI) anchors to newly synthesized proteins; human PIG-K protein is a functional homolog|Gpi8p; protein coding
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| YDR307W |
YDR307W |
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Putative protein of unknown function|Ydr307wp; protein coding
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| CSG2 |
CLS2YBR036C |
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Csg2p|Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations; protein coding
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| SSH1 |
YBR283C |
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Ssh1p|Subunit of the Ssh1 translocon complex; Sec61p homolog involved in co-translational pathway of protein translocation; not essential; protein coding
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| YPC1 |
YBR183W |
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Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity, catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance|Ypc1p; protein coding
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| MAL31 |
YBR298C |
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Mal31p|Maltose permease, high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL3 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters; functional in genomic reference strain S288C; protein coding
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| SUR2 |
SYR2YDR297W |
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Sphinganine C4-hydroxylase, catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis|Sur2p; protein coding
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| TSC13 |
YDL015C |
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Enoyl reductase that catalyzes the last step in each cycle of very long chain fatty acid elongation, localizes to the ER, highly enriched in a structure marking nuclear-vacuolar junctions, coimmunoprecipitates with elongases Fen1p and Sur4p|Tsc13p; protein coding
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| COS8 |
YHL048W |
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Cos8p|Nuclear membrane protein, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; regulation suggests a potential role in the unfolded protein response; protein coding
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| YHR140W |
YHR140W |
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Putative integral membrane protein of unknown function|Yhr140wp; protein coding
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| GAS3 |
YMR215W |
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Gas3p|Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall; protein coding
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| SWP1 |
YMR149W |
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Delta subunit of the oligosaccharyl transferase glycoprotein complex, which is required for N-linked glycosylation of proteins in the endoplasmic reticulum|Swp1p; protein coding
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| FET3 |
YMR058W |
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Ferro-O2-oxidoreductase required for high-affinity iron uptake and involved in mediating resistance to copper ion toxicity, belongs to class of integral membrane multicopper oxidases|Fet3p; protein coding
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| AVT4 |
YNL101W |
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Avt4p|Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters; protein coding
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| GPI2 |
GCR4YPL076W |
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Gpi2p|Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein; protein coding
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| SAM3 |
YPL274W |
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High-affinity S-adenosylmethionine permease, required for utilization of S-adenosylmethionine as a sulfur source; has similarity to S-methylmethionine permease Mmp1p|Sam3p; protein coding
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| YPL264C |
YPL264C |
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Putative membrane protein of unknown function; physically interacts with Hsp82p; YPL264C is not an essential gene|Ypl264cp; protein coding
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| HMG1 |
YML075C |
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Hmg1p|One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae; protein coding
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| ERV41 |
YML067C |
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Erv41p|Protein localized to COPII-coated vesicles, forms a complex with Erv46p; involved in the membrane fusion stage of transport; has homology to human ERGIC2 (PTX1) protein; protein coding
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| ELO1 |
YJL196C |
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Elo1p|Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids; protein coding
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| CHS7 |
YHR142W |
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Chs7p|Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p export from the ER; protein coding
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| SPC1 |
YJR010C-A |
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Spc1p|Subunit of the signal peptidase complex (SPC), which cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER), homolog of the SPC12 subunit of mammalian signal peptidase complex; protein coding
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| SAC1 |
RSD1YKL212W |
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Lipid phosphoinositide phosphatase of the ER and Golgi, involved in protein trafficking and secretion|Sac1p; protein coding
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| SEC61 |
YLR378C |
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Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER|Sec61p; protein coding
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| YLL023C |
YLL023C |
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Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum|Yll023cp; protein coding
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| SGE1 |
NOR1YPR198W |
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Plasma membrane multidrug transporter of the major facilitator superfamily, acts as an extrusion permease; partial multicopy suppressor of gal11 mutations|Sge1p; protein coding
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