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BioGRID | Network Layout for JSN1 for Saccharomyces cerevisiae
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JSN1

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: PUF1, YJR091C
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Jsn1p|Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; overexpression suppresses a tub2-150 mutation and causes increased sensitivity to benomyl in wild-type cells; protein coding
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [GeneDB]  [Germ Online]  [SGD]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 4 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with JSN1

JSN1 was identified with 29 protein interactions and 3 genetic interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 TUB2
  • ARM10
  • SHE8
  • YFL037W
    		•  The BioGRID Database Seperator Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules|Tub2p; protein coding
    Gene Ontology: [View List]
    Dosage Rescue
    bait Machin NA (1995)
    bait Machin NA (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FIS1
  • MDV2
  • YIL065C
    		•  The BioGRID Database Seperator Fis1p|Mitochondrial outer membrane protein involved in membrane fission, required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait Uetz P (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YLR392C
  • YLR392C
    		•  The BioGRID Database Seperator Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR392C is not an essential gene|Ylr392cp; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait Uetz P (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SPC34
  • YKR037C
    		•  The BioGRID Database Seperator Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; also localized to nuclear side of spindle pole body|Spc34p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait Uetz P (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PET20
  • YPL159C
    		•  The BioGRID Database Seperator Mitochondrial protein, required for respiratory growth under some conditions and for stability of the mitochondrial genome|Pet20p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FAA1
  • YOR317W
    		•  The BioGRID Database Seperator Faa1p|Long chain fatty acyl-CoA synthetase with a preference for C12:0-C16:0 fatty acids; involved in the activation of imported fatty acids; localized to both lipid particles and mitochondrial outer membrane; essential for stationary phase; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARC18
  • YLR370C
    		•  The BioGRID Database Seperator Arc18p|Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches; protein coding
    Gene Ontology: [View List]
    Co-localization
    hit Fehrenbacher KL (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CPR2
  • CYP2
  • YHR057C
    		•  The BioGRID Database Seperator Cpr2p|Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait Uetz P (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CLB2
  • YPR119W
    		•  The BioGRID Database Seperator B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome|Clb2p; protein coding
    Gene Ontology: [View List]
    Biochemical Activity
    bait Ubersax JA (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TIF1
  • YKR059W
    		•  The BioGRID Database Seperator Tif1p|Translation initiation factor eIF4A, identical to Tif2p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G; protein coding
    Gene Ontology: [View List]
    Protein-RNA
    hit Ulbricht RJ (2008)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MOT2
  • NOT4
  • SIG1
  • YER068W
    		•  The BioGRID Database Seperator Component of the CCR4-NOT complex, which has multiple roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; with Ubc4p, ubiquitylates subunits of the nascent polypeptide-associated complex (NAC)|Mot2p; protein coding
    Gene Ontology: [View List]
    PCA
    bait Tarassov K (2008)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HXK1
  • YFR053C
    		•  The BioGRID Database Seperator Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p|Hxk1p; protein coding
    Gene Ontology: [View List]
    Protein-RNA
    hit Ulbricht RJ (2008)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YJL107C
  • YJL107C
    		•  The BioGRID Database Seperator Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi|Yjl107cp; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Krogan NJ (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC28
  • CDK1
  • HSL5
  • SRM5
  • YBR160W
    		•  The BioGRID Database Seperator Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternately associates with G1 cyclins (CLNs) and G2/M cyclins (CLBs) which direct the CDK to specific substrates|Cdc28p; protein coding
    Gene Ontology: [View List]
    Biochemical Activity
    bait Ubersax JA (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HEX3
  • SLX5
  • YDL013W
    		•  The BioGRID Database Seperator Slx5p|Subunit of the Slx5-Slx8 substrate-specific ubiquitin ligase complex; stimulated by prior attachment of SUMO to the substrate; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RBL2
  • YOR265W
    		•  The BioGRID Database Seperator Protein involved in microtubule morphogenesis, required for protection from excess free beta-tubulin; proposed to be involved the folding of beta-tubulin; similar to mouse beta-tubulin cofactor A|Rbl2p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPA1
  • VMA16
  • YHR026W
    		•  The BioGRID Database Seperator Ppa1p|Subunit c'' of the vacuolar ATPase, which functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DID4
  • CHM2
  • GRD7
  • REN1
  • YKL002W
    		•  The BioGRID Database Seperator Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis|Did4p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC26
  • HIT3
  • SCD26
  • YFR036W
    		•  The BioGRID Database Seperator Cdc26p|Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VAC8
  • YEB3
  • YEL013W
    		•  The BioGRID Database Seperator Phosphorylated vacuolar membrane protein that interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions|Vac8p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPN5
  • NAS5
  • YDL147W
    		•  The BioGRID Database Seperator Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7p|Rpn5p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SAC7
  • YDR389W
    		•  The BioGRID Database Seperator GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate|Sac7p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RTS1
  • SCS1
  • YOR014W
    		•  The BioGRID Database Seperator B-type regulatory subunit of protein phosphatase 2A (PP2A); homolog of the mammalian B' subunit of PP2A|Rts1p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD27
  • ERC11
  • RTH1
  • FEN1
  • YKL113C
    		•  The BioGRID Database Seperator 5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family|Rad27p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBX4
  • CUI1
  • YMR067C
    		•  The BioGRID Database Seperator UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p|Ubx4p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YNR048W
  • CRF1
    		•  The BioGRID Database Seperator Protein proposed to interact with phospholipid translocases, shares similarity to Cdc50p|Ynr048wp; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     REX2
  • YNT20
  • YLR059C
    		•  The BioGRID Database Seperator RNA exonuclease, required for U4 snRNA maturation; functions redundantly with Rnh70p in 5.8S rRNA maturation, and with Rnh70p and Rex3p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases|Rex2p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF11
  • TAF40
  • YML015C
    		•  The BioGRID Database Seperator TFIID subunit (40 kDa), involved in RNA polymerase II transcription initiation, similar to histone H3 with atypical histone fold motif of Spt3-like transcription factors|Taf11p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     URA4
  • YLR420W
    		•  The BioGRID Database Seperator Dihydroorotase, catalyzes the third enzymatic step in the de novo biosynthesis of pyrimidines, converting carbamoyl-L-aspartate into dihydroorotate|Ura4p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YLR156W
  • YLR156W
    		•  The BioGRID Database Seperator Putative protein of unknown function; exhibits a two-hybrid interaction with Jsn1p in a large-scale analysis|Ylr156wp; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Ito T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MPT5
  • HTR1
  • PUF5
  • UTH4
  • YGL178W
    		•  The BioGRID Database Seperator Member of the Puf family of RNA-binding proteins; binds to mRNAs encoding chromatin modifiers and spindle pole body components; involved in longevity, maintenance of cell wall integrity, and sensitivity to and recovery from pheromone arrest|Mpt5p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Ulbricht RJ (2008)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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