| Name |
Aliases |
 |
Description |
| Evidence Code |
| Role |
Source [Interactions] |
|
|
|
| YGR068C |
YGR068C |
|
Putative protein of unknown function; YGR068C is not an essential gene.
|
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| SIN4 |
GAL22SDI3RYE1YNL236W |
|
Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; contributes to both postive and negative transcriptional regulation; dispensible for basal transcription
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| SHE2 |
YKL130C |
|
RNA-binding protein that binds specific mRNAs and interacts with She3p; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud
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| HSP60 |
MIF4CPN60YLR259C |
|
Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; phosphorylated
|
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| LTE1 |
MSI2YAL024C |
|
Putative GDP/GTP exchange factor required for mitotic exit at low temperatures; acts as a guanine nucleotide exchange factor (GEF) for Tem1p, which is a key regulator of mitotic exit; physically associates with Ras2p-GTP
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| SIN3 |
CPE1SDI1SDS16YOL004W |
|
Component of the Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity
|
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| SLX4 |
YLR135W |
|
Subunit of a complex, with Slx1p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p
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| EAF7 |
YNL136W |
|
Subunit of the NuA4 histone acetyltransferase complex, which acetylates the N-terminal tails of histones H4 and H2A
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| GET2 |
RMD7HUR2YER083C |
|
Subunit of the GET complex; required for meiotic nuclear division and for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion; may be involved in cell wall function
|
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| LGE1 |
YPL055C |
|
Protein of unknown function; null mutant forms abnormally large cells
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| GET1 |
MDM39YGL020C |
|
Subunit of the GET complex; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance
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| NAT1 |
AAA1YDL040C |
|
Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing
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| SIC1 |
SDB25YLR079W |
|
Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, preventing premature S phase and ensuring genomic integrity; phosphorylation targets Sic1p for SCF(CDC4)-dependent turnover; functional homolog of mammalian Kip1
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