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BioGRID | Network Layout for USE1 for Saccharomyces cerevisiae
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USE1

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: SLT1, YGL098W
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Essential SNARE protein localized to the ER, involved in retrograde traffic from the Golgi to the ER; forms a complex with the SNAREs Sec22p, Sec20p and Ufe1p|Use1p; protein coding
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [GeneDB]  [Germ Online]  [SGD]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 4 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with USE1

USE1 was identified with 29 protein interactions and 8 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 UFE1
  • YOR075W
    		•  The BioGRID Database Seperator Ufe1p|t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane protein that constitutes with Sec20p and Use1p the trimeric acceptor for R/v-SNAREs on Golgi-derived vesicles at the ER; part of Dsl1p complex; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Burri L (2003)
    hit Dilcher M (2003)
    bait Li Y (2005)
    hit Kraynack BA (2005)
    Affinity Capture-MS
    hit Gavin AC (2006)
    hit Collins SR (2007)
    Synthetic Lethality
    hit Dilcher M (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC20
  • YDR498C
    		•  The BioGRID Database Seperator Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to the ER; required for N- and O-glycosylation in the Golgi but not in the ER; forms a complex with the cytosolic Tip20p|Sec20p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Dilcher M (2003)
    bait/hit Kraynack BA (2005)
    Affinity Capture-MS
    bait Collins SR (2007)
    Synthetic Growth Defect
    hit Dilcher M (2003)
    Synthetic Lethality
    hit Dilcher M (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC22
  • SLY2
  • TSL26
  • YLR268W
    		•  The BioGRID Database Seperator R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi complex; involved in anterograde and retrograde transport between the ER and Golgi; synaptobrevin homolog|Sec22p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Burri L (2003)
    hit Dilcher M (2003)
    Affinity Capture-MS
    hit Collins SR (2007)
    Synthetic Growth Defect
    hit Dilcher M (2003)
    Synthetic Lethality
    hit Dilcher M (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DSL1
  • RNS1
  • YNL258C
    		•  The BioGRID Database Seperator Dsl1p|Peripheral membrane protein required for Golgi-to-ER retrograde traffic; component of the ER target site that interacts with coatomer, the major component of the COPI vesicle protein coat; also interacts with Cin5p and Sec39p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Kraynack BA (2005)
    Affinity Capture-MS
    bait/hit Gavin AC (2006)
    hit Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TIP20
  • TIP1
  • YGL145W
    		•  The BioGRID Database Seperator Peripheral membrane protein required for fusion of COPI vesicles with the ER, prohibits back-fusion of COPII vesicles with the ER, may act as a sensor for vesicles at the ER membrane; interacts with Sec20p|Tip20p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Kraynack BA (2005)
    Affinity Capture-MS
    bait/hit Gavin AC (2006)
    hit Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC39
  • YLR440C
    		•  The BioGRID Database Seperator Protein of unknown function proposed to be involved in protein secretion; interacts with Dsl1p and localizes to the ER and nuclear envelope|Sec39p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Kraynack BA (2005)
    Affinity Capture-MS
    hit Gavin AC (2006)
    hit Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YKT6
  • YKL196C
    		•  The BioGRID Database Seperator Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within the Golgi, endocytic trafficking to the vacuole, and vacuolar fusion; membrane localization due to prenylation at the carboxy-terminus|Ykt6p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Burri L (2003)
    Affinity Capture-MS
    hit Gavin AC (2006)
    hit Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ADH1
  • ADC1
  • YOL086C
    		•  The BioGRID Database Seperator Adh1p|Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SLY1
  • YDR189W
    		•  The BioGRID Database Seperator Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM (Sec1/Munc-18) family protein that binds the tSNARE Sed5p and stimulates its assembly into a trans-SNARE membrane-protein complex|Sly1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Li Y (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC61
  • YLR378C
    		•  The BioGRID Database Seperator Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER|Sec61p; protein coding
    Gene Ontology: [View List]
    Co-fractionation
    hit Dilcher M (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC17
  • RNS3
  • YBL050W
    		•  The BioGRID Database Seperator Peripheral membrane protein required for vesicular transport between ER and Golgi and for the 'priming' step in homotypic vacuole fusion, part of the cis-SNARE complex; has similarity to alpha-SNAP|Sec17p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Burri L (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ADP1
  • YCR011C
    		•  The BioGRID Database Seperator Adp1p|Putative ATP-dependent permease of the ABC transporter family of proteins; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SED5
  • YLR026C
    		•  The BioGRID Database Seperator Sed5p|cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and the Golgi complex, binds at least 9 SNARE proteins; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Dilcher M (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BOS1
  • SEC32
  • YLR078C
    		•  The BioGRID Database Seperator Bos1p|v-SNARE (vesicle specific SNAP receptor), localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Dilcher M (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BET1
  • SLY12
  • YIL004C
    		•  The BioGRID Database Seperator Bet1p|Type II membrane protein required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Dilcher M (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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