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BioGRID | Network Layout for EMP24 for Saccharomyces cerevisiae
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EMP24

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: BST2, YGL200C
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Emp24p|Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport; protein coding
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [GeneDB]  [Germ Online]  [SGD]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 9 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with EMP24

EMP24 was identified with 73 protein interactions and 38 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 ERP1
  • YAR002C-A
    		•  The BioGRID Database Seperator Erp1p|Protein that forms a heterotrimeric complex with Erp2p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    hit Krogan NJ (2006)
    bait/hit Gavin AC (2006)
    bait Collins SR (2007)
    Affinity Capture-Western
    bait Marzioch M (1999)
    Co-fractionation
    bait Otte S (2001)
    bait Marzioch M (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ERP2
  • YAL007C
    		•  The BioGRID Database Seperator Erp2p|Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002)
    bait Krogan NJ (2006)
    bait Gavin AC (2006)
    bait Collins SR (2007)
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ERV25
  • YML012W
    		•  The BioGRID Database Seperator Erv25p|Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family involved in endoplasmic reticulum to Golgi transport; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    Affinity Capture-Western
    hit Belden WJ (1996)
    Affinity Capture-MS
    hit Krogan NJ (2006)
    bait/hit Gavin AC (2006)
    hit Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SAR1
  • YPL218W
    		•  The BioGRID Database Seperator GTPase, GTP-binding protein of the ARF family, component of COPII coat of vesicles; required for transport vesicle formation during ER to Golgi protein transport|Sar1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kuehn MJ (1998)
    Reconstituted Complex
    hit Belden WJ (2001)
    Co-purification
    bait Kuehn MJ (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAS1
  • CWH52
  • GGP1
  • YMR307W
    		•  The BioGRID Database Seperator Beta-1,3-glucanosyltransferase, required for cell wall assembly; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor|Gas1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Muñiz M (2000)
    Synthetic Lethality
    bait Tong AH (2004)
    bait Lesage G (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ERP4
  • YOR016C
    		•  The BioGRID Database Seperator Erp4p|Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    Affinity Capture-MS
    hit Collins SR (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SED5
  • YLR026C
    		•  The BioGRID Database Seperator Sed5p|cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and the Golgi complex, binds at least 9 SNARE proteins; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Cho JH (2000)
    Co-purification
    bait Inadome H (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC13
  • ANU3
  • YLR208W
    		•  The BioGRID Database Seperator Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (Sar1p, Sec13p, Sec16p, Sec23p, Sec24p, Sec31p, Sfb2p, and Sfb3p) which is important for the formation of ER to Golgi transport vesicles|Sec13p; protein coding
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Belden WJ (2001)
    Synthetic Rescue
    bait Elrod-Erickson MJ (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CHS1
  • USA4
  • YNL192W
    		•  The BioGRID Database Seperator Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for repairing the chitin septum during cytokinesis; transcription activated by mating factor|Chs1p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Tong AH (2004)
    bait Lesage G (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CHS3
  • CAL1
  • CSD2
  • DIT101
  • YBR023C
    		•  The BioGRID Database Seperator Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan|Chs3p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Tong AH (2004)
    bait Lesage G (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CPT1
  • YNL130C
    		•  The BioGRID Database Seperator Cholinephosphotransferase, required for phosphatidylcholine biosynthesis and for inositol-dependent regulation of EPT1 transcription|Cpt1p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     OPT2
  • YPR194C
    		•  The BioGRID Database Seperator Oligopeptide transporter; member of the OPT family, with potential orthologs in S. pombe and C. albicans|Opt2p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPN5
  • NAS5
  • YDL147W
    		•  The BioGRID Database Seperator Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7p|Rpn5p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ho Y (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRM10
  • YJL108C
    		•  The BioGRID Database Seperator Pheromone-regulated protein, predicted to have 5 transmembrane segments|Prm10p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EMP24
  • BST2
  • YGL200C
    		•  The BioGRID Database Seperator Emp24p|Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ERP5
  • YHR110W
    		•  The BioGRID Database Seperator Erp5p|Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PHO88
  • YBR106W
    		•  The BioGRID Database Seperator Pho88p|Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DNF1
  • YER166W
    		•  The BioGRID Database Seperator Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase|Dnf1p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAT1
  • VAP1
  • TAP1
  • YBR069C
    		•  The BioGRID Database Seperator Amino acid transport protein for valine, leucine, isoleucine, and tyrosine, low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance|Tat1p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC23
  • YPR181C
    		•  The BioGRID Database Seperator GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat, involved in ER to Golgi transport and autophagy; stimulates the GDP-bound form of Sar1p|Sec23p; protein coding
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Belden WJ (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TPO2
  • YGR138C
    		•  The BioGRID Database Seperator Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily|Tpo2p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC31
  • WEB1
  • YDL195W
    		•  The BioGRID Database Seperator Essential phosphoprotein component (p150) of the COPII coat of secretory pathway vesicles, in complex with Sec13p; required for ER-derived transport vesicle formation|Sec31p; protein coding
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Belden WJ (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GSY1
  • YFR015C
    		•  The BioGRID Database Seperator Glycogen synthase with similarity to Gsy2p, the more highly expressed yeast homolog; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase|Gsy1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STM1
  • MPT4
  • YLR150W
    		•  The BioGRID Database Seperator Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations|Stm1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ERP3
  • YDL018C
    		•  The BioGRID Database Seperator Erp3p|Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NMD5
  • KAP119
  • YJR132W
    		•  The BioGRID Database Seperator Karyopherin, a carrier protein involved in nuclear import of proteins; importin beta homolog|Nmd5p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YRA1
  • SHE11
  • YDR381W
    		•  The BioGRID Database Seperator Nuclear protein that binds to RNA and to Mex67p, required for export of poly(A)+ mRNA from the nucleus; member of the REF (RNA and export factor binding proteins) family; another family member, Yra2p, can substitute for Yra1p function|Yra1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HMO1
  • HSM2
  • YDR174W
    		•  The BioGRID Database Seperator Chromatin associated high mobility group (HMG) family member involved in genome maintenance; rDNA-binding component of the Pol I transcription system; associates with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase|Hmo1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ALG1
  • YBR110W
    		•  The BioGRID Database Seperator Alg1p|Mannosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum (ER); essential for viability, mutation is functionally complemented by human ortholog; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARR3
  • ACR3
  • YPR201W
    		•  The BioGRID Database Seperator Arr3p|Arsenite transporter of the plasma membrane, required for resistance to arsenic compounds; transcription is activated by Arr1p in the presence of arsenite; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PBP4
  • YDL053C
    		•  The BioGRID Database Seperator Pbp1p binding protein, interacts strongly with Pab1p-binding protein 1 (Pbp1p) in the yeast two-hybrid system; also interacts with Lsm12p in a copurification assay|Pbp4p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC24
  • ANU1
  • YIL109C
    		•  The BioGRID Database Seperator Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; involved in ER to Golgi transport, cargo selection and autophagy; required for the binding of the Sec13 complex to ER membranes; homologous to Lst1p and Lss1p|Sec24p; protein coding
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Belden WJ (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NOP1
  • LOT3
  • YDL014W
    		•  The BioGRID Database Seperator Nop1p|Nucleolar protein, component of the small subunit processome complex, which is required for processing of pre-18S rRNA; has similarity to mammalian fibrillarin; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STE24
  • AFC1
  • PIO2
  • YJR117W
    		•  The BioGRID Database Seperator Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans|Ste24p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YET1
  • YKL065C
    		•  The BioGRID Database Seperator Endoplasmic reticulum transmembrane protein; may interact with ribosomes, based on co-purification experiments; homolog of human BAP31 protein|Yet1p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PHO86
  • YJL117W
    		•  The BioGRID Database Seperator Endoplasmic reticulum (ER) resident protein required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles|Pho86p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNL1
  • YIL016W
    		•  The BioGRID Database Seperator Protein of unknown function proposed to be involved in nuclear pore complex biogenesis and maintenance as well as protein folding; has similarity to the mammalian BAG-1 protein|Snl1p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YHR140W
  • YHR140W
    		•  The BioGRID Database Seperator Putative integral membrane protein of unknown function|Yhr140wp; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRP102
  • YKL154W
    		•  The BioGRID Database Seperator Signal recognition particle (SRP) receptor beta subunit; involved in SRP-dependent protein targeting; anchors Srp101p to the ER membrane|Srp102p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC61
  • YLR378C
    		•  The BioGRID Database Seperator Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER|Sec61p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Miller JP (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YBR159W
  • IFA38
    		•  The BioGRID Database Seperator Ifa38p|Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides; protein coding
    Gene Ontology: [View List]