| Name |
Aliases |
 |
Description |
|
|
| CSG2 |
CLS2YBR036C |
|
Csg2p|Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations; protein coding
|
|
|
|
|
| AGP1 |
YCC5YCL025C |
|
Agp1p|Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p); protein coding
|
|
|
|
|
| GPI8 |
YDR331W |
|
ER membrane glycoprotein subunit of the glycosylphosphatidylinositol transamidase complex that adds glycosylphosphatidylinositol (GPI) anchors to newly synthesized proteins; human PIG-K protein is a functional homolog|Gpi8p; protein coding
|
|
|
|
|
| ERD1 |
LDB2YDR414C |
|
Erd1p|Predicted membrane protein required for the retention of lumenal endoplasmic reticulum proteins; mutants secrete the endogenous ER protein, BiP (Kar2p); protein coding
|
|
|
|
|
| GNP1 |
YDR508C |
|
Gnp1p|High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids; protein coding
|
|
|
|
|
| WBP1 |
YEL002C |
|
Beta subunit of the oligosaccharyl transferase (OST) glycoprotein complex; required for N-linked glycosylation of proteins in the endoplasmic reticulum|Wbp1p; protein coding
|
|
|
|
|
| YDR307W |
YDR307W |
|
Putative protein of unknown function|Ydr307wp; protein coding
|
|
|
|
|
| TLG1 |
YDR468C |
|
Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds the docking complex VFT (Vps fifty-three) through interaction with Vps51p|Tlg1p; protein coding
|
|
|
|
|
| SUR2 |
SYR2YDR297W |
|
Sphinganine C4-hydroxylase, catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis|Sur2p; protein coding
|
|
|
|
|
| MCH1 |
YDL054C |
|
Mch1p|Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport; protein coding
|
|
|
|
|
| PMP1 |
YCR024C-A |
|
Pmp1p|Small single-membrane span proteolipid that functions as a regulatory subunit of the plasma membrane H(+)-ATPase Pma1p, forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines; protein coding
|
|
|
|
|
| YDL206W |
YDL206W |
|
Putative protein of unknown function; YDL206W is not an essential protein|Ydl206wp; protein coding
|
|
|
|
|
| UGA4 |
YDL210W |
|
Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane|Uga4p; protein coding
|
|
|
|
|
| BAP3 |
PAP1YDR046C |
|
Amino acid permease involved in the uptake of cysteine, leucine, isoleucine and valine|Bap3p; protein coding
|
|
|
|
|
| PMP2 |
YEL017C-A |
|
Pmp2p|Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; nearly identical to PMP1; protein coding
|
|
|
|
|
| CAN1 |
YEL063C |
|
Can1p|Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance; protein coding
|
|
|
|
|
| TNA1 |
YGR260W |
|
High affinity nicotinic acid plasma membrane permease, responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA)|Tna1p; protein coding
|
|
|
|
|
| HIP1 |
YGR191W |
|
High-affinity histidine permease, also involved in the transport of manganese ions|Hip1p; protein coding
|
|
|
|
|
| ARR3 |
ACR3YPR201W |
|
Arr3p|Arsenite transporter of the plasma membrane, required for resistance to arsenic compounds; transcription is activated by Arr1p in the presence of arsenite; protein coding
|
|
|
|
|
| YHL042W |
YHL042W |
|
Putative protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins|Yhl042wp; protein coding
|
|
|
|
|
| PPA1 |
VMA16YHR026W |
|
Ppa1p|Subunit c'' of the vacuolar ATPase, which functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain; protein coding
|
|
|
|
|
| COS8 |
YHL048W |
|
Cos8p|Nuclear membrane protein, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; regulation suggests a potential role in the unfolded protein response; protein coding
|
|
|
|
|
| YIP1 |
YGR172C |
|
Integral membrane protein required for the biogenesis of ER-derived COPII transport vesicles; interacts with Yif1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles|Yip1p; protein coding
|
|
|
|
|
| ERG25 |
YGR060W |
|
C-4 methyl sterol oxidase, catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol|Erg25p; protein coding
|
|
|
|
|
| COS4 |
YFL062W |
|
Cos4p|Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; protein coding
|
|
|
|
|
| EMP47 |
YFL048C |
|
Emp47p|Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport; protein coding
|
|
|
|
|
| OLE1 |
MDM2YGL055W |
|
Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria|Ole1p; protein coding
|
|
|
|
|
| VPS73 |
YGL104C |
|
Mitochondrial protein; mutation affects vacuolar protein sorting; putative transporter; member of the sugar porter family|Vps73p; protein coding
|
|
|
|
|
| EMP24 |
BST2YGL200C |
|
Emp24p|Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport; protein coding
|
|
|
|
|
| ADP1 |
YCR011C |
|
Adp1p|Putative ATP-dependent permease of the ABC transporter family of proteins; protein coding
|
|
|
|
|
| MAL31 |
YBR298C |
|
Mal31p|Maltose permease, high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL3 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters; functional in genomic reference strain S288C; protein coding
|
|
|
|
|
| ARP3 |
ACT4YJR065C |
|
Arp3p|Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity; protein coding
|
|
|
|
|
| COF1 |
YLL050C |
|
Cof1p|Cofilin, promotes actin filament depolarization in a pH-dependent manner; binds both actin monomers and filaments and severs filaments , thought to be regulated by phosphorylation at SER4, ubiquitous and essential in eukaryotes; protein coding
|
|
|
|
|
| YJL123C |
YJL123C |
|
Protein of unknown function that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); YJL123C is a non-essential gene|Yjl123cp; protein coding
|
|
|
|
|
| SLM1 |
LIT2YIL105C |
|
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; subunit of and phosphorylated by the TORC2 complex|Slm1p; protein coding
|
|
|
|
|
| PMA1 |
YGL008C |
|
Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plasma membrane potential; part of the P2 subgroup of cation-transporting ATPases|Pma1p; protein coding
|
|
|
|
|
| CDC3 |
YLR314C |
|
Cdc3p|Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM; protein coding
|
|
|
|
|
| CRN1 |
YLR429W |
|
Coronin, cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regulate its activity|Crn1p; protein coding
|
|
|
|
|
| KSP1 |
YHR082C |
|
Ksp1p|Nonessential putative serine/threonine protein kinase of unknown cellular role; overproduction causes allele-specific suppression of the prp20-10 mutation; protein coding
|
|
|
|
|
| YJL097W |
PHS1 |
|
Phs1p|Protein of unknown function; homolog of mammalian PTPLA; involved in sphingolipid biosynthesis, protein trafficking; required for cell viability; protein coding
|
|
|
|
|
| KIN4 |
KIN3KIN31YOR233W |
|
Kin4p|Serine/threonine protein kinase that inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck; protein coding
|
|
|
|
|
| ARC35 |
END9YNR035C |
|
Arc35p|Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches; required for cortical localization of calmodulin; protein coding
|
|
|
|
|
| POR1 |
OMP2YNL055C |
|
Mitochondrial porin (voltage-dependent anion channel), outer membrane protein required for the maintenance of mitochondrial osmotic stability and mitochondrial membrane permeability; phosphorylated|Por1p; protein coding
|
|
|
|
|
| YRA1 |
SHE11YDR381W |
|
Nuclear protein that binds to RNA and to Mex67p, required for export of poly(A)+ mRNA from the nucleus; member of the REF (RNA and export factor binding proteins) family; another family member, Yra2p, can substitute for Yra1p function|Yra1p; protein coding
|
|
|
|
|
| HMO1 |
HSM2YDR174W |
|
Chromatin associated high mobility group (HMG) family member involved in genome maintenance; rDNA-binding component of the Pol I transcription system; associates with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase|Hmo1p; protein coding
|
|
|
|
|
| YPC1 |
YBR183W |
|
Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity, catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance|Ypc1p; protein coding
|
|
