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BioGRID | Network Layout for BOI1 for Saccharomyces cerevisiae
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BOI1

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: BOB1, GIN7, YBL085W
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [UniprotKB] | [SGD] | [Entrez Gene] | [GeneDB]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 12 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with BOI1

BOI1 was identified with 71 protein interactions and 26 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code
Role Source [Interactions]
The BioGRID Database Seperator
 BEM1
  • SRO1
  • YBR200W
    		•  The BioGRID Database Seperator Protein containing SH3-domains, involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p
    Gene Ontology: [View List]
    Two-hybrid
    hit Bender L (1996) [9]
    bait Tonikian R (2009) [751]
    Affinity Capture-MS
    bait McCusker D (2007) [12]
    PCA
    hit Tarassov K (2008) [2616]
    Negative Genetic
    bait Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ZDS2
  • CES4
  • YML109W
    		•  The BioGRID Database Seperator Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; paralog of Zds1p
    Gene Ontology: [View List]
    Two-hybrid
    hit Drees BL (2001) [205]
    hit Tong AH (2002) [250]
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DSE1
  • YER124C
    		•  The BioGRID Database Seperator Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall
    Gene Ontology: [View List]
    Two-hybrid
    hit Drees BL (2001) [205]
    hit Tong AH (2002) [250]
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BOI2
  • BEB1
  • YER114C
    		•  The BioGRID Database Seperator Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Matsui Y (1996) [7]
    hit Bender L (1996) [9]
    Negative Genetic
    hit Fiedler D (2009) [4053]
    bait Costanzo M (2010) [68487]
    Synthetic Growth Defect
    hit Kozubowski L (2008) [14]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YJR056C
  • YJR056C
    		•  The BioGRID Database Seperator Yjr056cp
    Gene Ontology: [View List]
    Two-hybrid
    hit Tong AH (2002) [250]
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NIS1
  • JIP1
  • YNL078W
    		•  The BioGRID Database Seperator Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network
    Gene Ontology: [View List]
    Two-hybrid
    hit Tong AH (2002) [250]
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YER158C
  • YER158C
    		•  The BioGRID Database Seperator Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p
    Gene Ontology: [View List]
    Two-hybrid
    hit Tong AH (2002) [250]
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AFR1
  • YDR085C
    		•  The BioGRID Database Seperator Alpha-factor pheromone receptor regulator, negatively regulates pheromone receptor signaling; required for normal mating projection (shmoo) formation; required for Spa2p to recruit Mpk1p to shmoo tip during mating; interacts with Cdc12p
    Gene Ontology: [View List]
    Two-hybrid
    hit Tong AH (2002) [250]
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC24
  • CLS4
  • YAL041W
    		•  The BioGRID Database Seperator Guanine nucleotide exchange factor (GEF or GDP-release factor) for Cdc42p; required for polarity establishment and maintenance, and mutants have morphological defects in bud formation and shmooing
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait McCusker D (2007) [12]
    Affinity Capture-MS
    bait McCusker D (2007) [12]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STE20
  • YHL007C
    		•  The BioGRID Database Seperator Signal transducing kinase of the PAK (p21-activated kinase) family, involved in pheromone response and pseudohyphal/invasive growth pathways, activated by Cdc42p; binds Ste4p at a GBB motif present in noncatalytic domains of PAK kinases
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Drees BL (2001) [205]
    Biochemical Activity
    bait Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC3
  • PSL1
  • YER008C
    		•  The BioGRID Database Seperator Non-essential subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    Negative Genetic
    bait Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC42
  • YLR229C
    		•  The BioGRID Database Seperator Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins
    Gene Ontology: [View List]
    Two-hybrid
    hit Bender L (1996) [9]
    Dosage Rescue
    hit Bender L (1996) [9]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RHO4
  • YKR055W
    		•  The BioGRID Database Seperator Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely to be involved in the establishment of cell polarity
    Gene Ontology: [View List]
    Dosage Rescue
    hit Matsui Y (1996) [7]
    hit Bender L (1996) [9]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RHO3
  • YIL118W
    		•  The BioGRID Database Seperator Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
    Gene Ontology: [View List]
    Dosage Rescue
    hit Matsui Y (1996) [7]
    hit Bender L (1996) [9]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AIM44
  • YPL158C
    		•  The BioGRID Database Seperator Protein of unknown function; null mutant displays increased frequency of mitochondrial genome loss (petite formation) and reduced growth rate in minimal glycerol media
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC55
  • YGL190C
    		•  The BioGRID Database Seperator Non-essential regulatory subunit B of protein phosphatase 2A, which has multiple roles in mitosis and protein biosynthesis; involved in regulation of mitotic exit; found in the nucleus of most cells, also at the bud neck and at the bud tip
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DIG1
  • RST1
  • YPL049C
    		•  The BioGRID Database Seperator Regulatory protein of unknown function, constitutively-expressed, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DIG2
  • RST2
  • YDR480W
    		•  The BioGRID Database Seperator Regulatory protein of unknown function, pheromone-inducible, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NBA1
  • YOL070C
    		•  The BioGRID Database Seperator Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, and bud neck; potential Cdc28p substrate
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HXT11
  • LGT3
  • YOL156W
    		•  The BioGRID Database Seperator Putative hexose transporter that is nearly identical to Hxt9p, has similarity to major facilitator superfamily (MFS) transporters and is involved in pleiotropic drug resistance
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YBR238C
  • YBR238C
    		•  The BioGRID Database Seperator Mitochondrial membrane protein with similarity to Rmd9p; not required for respiratory growth but causes a synthetic respiratory defect in combination with rmd9 mutations; transcriptionally up-regulated by TOR; deletion increases life span
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Gavin AC (2002) [3400]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YMR244W
  • YMR244W
    		•  The BioGRID Database Seperator Putative protein of unknown function
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YNL234W
  • YNL234W
    		•  The BioGRID Database Seperator Similar to globins and has a functional heme-binding domain; involved in glucose signaling or metabolism; regulated by Rgt1p
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YOL019W
  • YOL019W
    		•  The BioGRID Database Seperator Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRY1
  • YKL218C
    		•  The BioGRID Database Seperator 3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YDR239C
  • YDR239C
    		•  The BioGRID Database Seperator Protein of unknown function that may interact with ribosomes, based on co-purification experiments
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STD1
  • SFS3
  • MSN3
  • YOR047C
    		•  The BioGRID Database Seperator Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YMR124W
  • YMR124W
    		•  The BioGRID Database Seperator Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; interacts with Crm1p in two-hybrid assay; YMR124W is not an essential gene
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NAB2
  • YGL122C
    		•  The BioGRID Database Seperator Nuclear polyadenylated RNA-binding protein; autoregulates mRNA levels; related to human hnRNPs; has nuclear localization signal sequence that binds to Kap104p; required for poly(A) tail length control and nuclear mRNA export
    Gene Ontology: [View List]
    Affinity Capture-RNA
    bait Batisse J (2009) [2548]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SER3
  • YER081W
    		•  The BioGRID Database Seperator 3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser33p
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RTT106
  • YNL206C
    		•  The BioGRID Database Seperator Protein with a role in regulation of Ty1 transposition
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MIG1
  • TDS22
  • SSN1
  • CAT4
  • YGL035C
    		•  The BioGRID Database Seperator Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MTH1
  • DGT1
  • HTR1
  • BPC1
  • YDR277C
    		•  The BioGRID Database Seperator Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PHO4
  • YFR034C
    		•  The BioGRID Database Seperator Basic helix-loop-helix (bHLH) transcription factor of the myc-family; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RIM11
  • MDS1
  • GSK3
  • YMR139W
    		•  The BioGRID Database Seperator Protein kinase required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MET31
  • YPL038W
    		•  The BioGRID Database Seperator Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met32p
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YJR061W
  • YJR061W
    		•  The BioGRID Database Seperator Putative protein of unknown function; non-essential gene with similarity to Mnn4, a putative membrane protein involved in glycosylation; transcription repressed by Rm101p
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC3
  • YLR314C
    		•  The BioGRID Database Seperator Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BEM2
  • IPL2
  • SUP9
  • TSL1
  • YER155C
    		•  The BioGRID Database Seperator Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CHD1
  • YER164W
    		•  The BioGRID Database Seperator Nucleosome remodeling factor that functions in regulation of transcription elongation; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SILK complexes
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     COQ1
  • YBR003W
    		•  The BioGRID Database Seperator Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EHD3
  • MRP5
  • YDR036C
    		•  The BioGRID Database Seperator 3-hydroxyisobutyryl-CoA hydrolase, member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AIM3
  • YBR108W
    		•  The BioGRID Database Seperator Protein interacting with Rsv167p; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LGE1
  • YPL055C
    		•  The BioGRID Database Seperator Protein of unknown function; null mutant forms abnormally large cells
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Lambert JP (2009) [269]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HOF1
  • CYK2
  • YMR032W
    		•  The BioGRID Database Seperator Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p
    Gene Ontology: [View List]
    Two-hybrid
    hit Tong AH (2002) [250]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAB1
  • YER165W
    		•  The BioGRID Database Seperator Poly(A) binding protein, part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2006) [7592]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TPK1
  • SRA3
  • PKA1
  • YJL164C
    		•  The BioGRID Database Seperator cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk2p and Tpk3p
    Gene Ontology: [View List]
    Biochemical Activity
    bait Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HEK2
  • KHD1
  • YBL032W
    		•  The BioGRID Database Seperator RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length
    Gene Ontology: [View List]
    Affinity Capture-RNA
    bait Hasegawa Y (2008) [1095]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EXO84
  • USA3
  • YBR102C
    		•  The BioGRID Database Seperator Essential protein with dual roles in spliceosome assembly and exocytosis; the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p) mediates polarized targeting of secretory vesicles to active sites of exocytosis
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ACC1
  • MTR7
  • ABP2
  • FAS3
  • YNR016C
    		•  The BioGRID Database Seperator Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RRP7
  • YCL031C
    		•  The BioGRID Database Seperator Essential protein involved in rRNA processing and ribosome biogenesis
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VPS13
  • SOI1
  • VPT2
  • YLL040C
    		•  The BioGRID Database Seperator Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; homologous to human COH1; involved in sporulation, vacuolar protein sorting and protein-Golgi retention
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VPS74
  • API1
  • YDR372C
    		•  The BioGRID Database Seperator Non-essential protein of unknown function involved in vacuolar protein sorting; belongs to a family of cytosolic Golgi-associated proteins suggesting that it may play a role in secretion; also detected in the nucleus
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FBP26
  • YJL155C
    		•  The BioGRID Database Seperator Fructose-2,6-bisphosphatase, required for glucose metabolism
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PEX3
  • PAS3
  • YDR329C
    		•  The BioGRID Database Seperator Peroxisomal membrane protein (PMP) required required for the proper localization and stability of PMPs; interacts with Pex19p
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TID3
  • NDC80
  • HEC1
  • YIL144W
    		•  The BioGRID Database Seperator Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); conserved coiled-coil protein involved in chromosome segregation, spindle checkpoint activity, kinetochore assembly and clustering
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MED7
  • YOL135C
    		•  The BioGRID Database Seperator Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FIR1
  • PIP1
  • YER032W
    		•  The BioGRID Database Seperator Protein involved in 3' mRNA processing, interacts with Ref2p; potential Cdc28p substrate
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IML1
  • YJR138W
    		•  The BioGRID Database Seperator Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KCC4
  • YCL024W
    		•  The BioGRID Database Seperator Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MCM6
  • YGL201C
    		•  The BioGRID Database Seperator Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
    Gene Ontology: [View List]
    Two-hybrid
    hit Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC15
  • YGL233W
    		•  The BioGRID Database Seperator Essential 113kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which mediates polarized targeting of vesicles to active sites of exocytosis; Sec15p associates with Sec4p and vesicles
    Gene Ontology: [View List]
    Negative Genetic
    bait Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EMI1
  • YDR512C
    		•  The BioGRID Database Seperator Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation
    Gene Ontology: [View List]
    Positive Genetic
    bait Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC9
  • HSS7
  • YGR009C
    		•  The BioGRID Database Seperator t-SNARE protein important for fusion of secretory vesicles with the plasma membrane; similar to but not functionally redundant with Spo20p; SNAP-25 homolog
    Gene Ontology: [View List]
    Negative Genetic
    bait Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IES3
  • YLR052W
    		•  The BioGRID Database Seperator Subunit of the INO80 chromatin remodeling complex
    Gene Ontology: [View List]
    Negative Genetic
    bait Hannum G (2009) [496]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ABD1
  • YBR236C
    		•  The BioGRID Database Seperator Methyltransferase, catalyzes the transfer of a methyl group from S-adenosylmethionine to the GpppN terminus of capped mRNA
    Gene Ontology: [View List]
    Negative Genetic
    bait Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JNM1
  • INS1
  • PAC3
  • YMR294W
    		•  The BioGRID Database Seperator Component of the yeast dynactin complex, consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B
    Gene Ontology: [View List]
    Negative Genetic
    bait Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YLR152C
  • YLR152C
    		•  The BioGRID Database Seperator Putative protein of unknown function; YLR152C is not an essential gene
    Gene Ontology: [View List]
    Negative Genetic
    bait Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MRE11
  • XRS4
  • NGS1
  • RAD58
  • YMR224C
    		•  The BioGRID Database Seperator Subunit of a complex with Rad50p and Xrs2p (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability, exhibits nuclease activity that appears to be required for RMX function; widely conserved
    Gene Ontology: [View List]
    Synthetic Growth Defect
    bait Norden C (2006) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SWI5
  • YDR146C
    		•  The BioGRID Database Seperator Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase
    Gene Ontology: [View List]
    Positive Genetic
    bait Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YKU70
  • HDF1
  • NES24
  • YMR284W
    		•  The BioGRID Database Seperator Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair
    Gene Ontology: [View List]
    Synthetic Growth Defect
    bait Norden C (2006) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ELM1
  • LDB9
  • YKL048C
    		•  The BioGRID Database Seperator Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis; required for the regulation of other kinases; forms part of the bud neck ring
    Gene Ontology: [View List]
    Negative Genetic
    bait Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTK1
  • STK1
  • KKT8
  • YKT9
  • YKL198C
    		•  The BioGRID Database Seperator Putative serine/threonine protein kinase that regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein
    Gene Ontology: [View List]
    Positive Genetic
    bait Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CKA2
  • YOR29-12
  • YOR061W
    		•  The BioGRID Database Seperator Alpha' catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases
    Gene Ontology: [View List]
    Positive Genetic
    bait Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RSR1
  • BUD1
  • YGR152C
    		•  The BioGRID Database Seperator GTP-binding protein of the ras superfamily required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Kozubowski L (2008) [14]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    terms and conditions - privacy policy - Osprey Network Visualization System
    BioGRID: A General Repository for Interaction Datasets.
    Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
    Nucleic Acids Res. Jan 1;34:D535-9.