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BioGRID | Network Layout for SNF1 for Saccharomyces cerevisiae
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SNF1

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: CAT1, PAS14, HAF3, GLC2, CCR1, YDR477W
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [UniprotKB] | [SGD] | [Entrez Gene] | [GeneDB]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 31 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with SNF1

SNF1 was identified with 258 protein interactions and 262 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code
Role Source [Interactions]
The BioGRID Database Seperator
 SNF4
  • CAT3
  • SCI1
  • YGL115W
    		•  The BioGRID Database Seperator Activating gamma subunit of the AMP-activated Snf1p kinase complex (contains Snf1p and a Sip1p/Sip2p/Gal83p family member); activates glucose-repressed genes, represses glucose-induced genes; role in sporulation, and peroxisome biogenesis
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Gavin AC (2002) [3400]
    hit Ho Y (2002) [3666]
    hit Elbing K (2006) [16]
    hit Lo WS (2005) [5]
    hit Krogan NJ (2006) [7079]
    bait/hit Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    Reconstituted Complex
    bait Jiang R (1997) [9]
    Two-hybrid
    hit Hahn JS (2004) [3]
    hit Gimeno-Alcaniz JV (2003) [1]
    hit Rodriguez C (2003) [1]
    hit Willer M (2003) [4]
    hit Hou MC (2003) [10]
    hit Fichtner L (2002) [6]
    hit Dagkessamanskaia A (2001) [4]
    hit Shirra MK (1999) [4]
    hit Peng R (1999) [6]
    hit Yang X (1998) [7]
    hit Ludin K (1998) [2]
    hit Vidan S (1997) [3]
    hit Van Aelst L (1993) [1]
    hit Fields S (1989) [1]
    bait Srivastava A (2000) [8]
    bait Rodal AA (1999) [11]
    hit Jiang R (1996) [1]
    hit Chimura T (2002) [13]
    hit Russell SJ (1996) [4]
    hit Faulstich D (1996) [7]
    hit Camasses A (1998) [5]
    hit Brown CE (1996) [4]
    hit Naik RR (1998) [2]
    hit La Rue J (2005) [5]
    hit Metz J (2006) [5]
    hit Nadeem FK (2006) [3]
    hit Soler M (1995) [5]
    hit Yu H (2008) [1778]
    bait Boysen JH (2009) [2]
    hit MacKinnon MA (2009) [2]
    Co-purification
    bait Jiang R (1997) [9]
    Co-crystal Structure
    bait Amodeo GA (2007) [2]
    Dosage Rescue
    bait Celenza JL (1989) [1]
    bait Celenza JL (1989) [1]
    Synthetic Rescue
    bait Estruch F (1992) [1]
    Synthetic Growth Defect
    hit Shirra MK (2005) [6]
    Phenotypic Enhancement
    hit Usaite R (2008) [1]
    hit Usaite R (2009) [1]
    Positive Genetic
    hit Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MIG1
  • TDS22
  • SSN1
  • CAT4
  • YGL035C
    		•  The BioGRID Database Seperator Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Treitel MA (1998) [2]
    bait Ahuatzi D (2007) [3]
    Two-hybrid
    hit Treitel MA (1998) [2]
    Biochemical Activity
    hit Leech A (2003) [1]
    hit Nath N (2002) [1]
    hit Smith FC (1999) [1]
    hit Ptacek J (2005) [4183]
    hit Elbing K (2006) [3]
    hit Nath N (2003) [6]
    Phenotypic Enhancement
    bait Balciunas D (1999) [21]
    hit Song W (1998) [12]
    Synthetic Rescue
    hit Zhou H (2001) [7]
    hit Rahner A (1996) [1]
    hit Vallier LG (1994) [1]
    hit Schueller HJ (1991) [2]
    hit Carlson M (1984) [8]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIP1
  • YDR422C
    		•  The BioGRID Database Seperator Alternate beta-subunit of the Snf1p kinase complex, may confer substrate specificity; vacuolar protein containing KIS (Kinase-Interacting Sequence) and ASC (Association with Snf1 kinase Complex) domains involved in protein interactions
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    hit Elbing K (2006) [16]
    bait Krogan NJ (2006) [7079]
    hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Affinity Capture-Western
    hit Yang X (1994) [3]
    hit Yang X (1992) [5]
    Two-hybrid
    bait Jiang R (1997) [9]
    hit Shields CM (2003) [5]
    hit Yang X (1992) [5]
    hit Nazarenus T (2005) [5]
    Dosage Rescue
    hit Long RM (1995) [1]
    Negative Genetic
    hit Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAL83
  • SPM1
  • YER027C
    		•  The BioGRID Database Seperator One of three possible beta-subunits of the Snf1 kinase complex, allows nuclear localization of the Snf1 kinase complex in the presence of a nonfermentable carbon source; contains glycogen-binding domain
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    hit Ho Y (2002) [3666]
    hit Elbing K (2006) [16]
    hit Lo WS (2005) [5]
    hit Krogan NJ (2006) [7079]
    hit Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    Two-hybrid
    hit Ito T (2001) [1585]
    hit Uetz P (2000) [875]
    bait Jiang R (1997) [9]
    Affinity Capture-Western
    hit Yang X (1994) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SAK1
  • PAK1
  • YER129W
    		•  The BioGRID Database Seperator Upstream serine/threonine kinase for the SNF1 complex; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    hit Elbing K (2006) [16]
    bait Krogan NJ (2006) [7079]
    hit Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    Affinity Capture-Western
    hit Nath N (2003) [6]
    bait Elbing K (2006) [16]
    hit Elbing K (2006) [3]
    Biochemical Activity
    bait Nath N (2003) [6]
    bait Elbing K (2006) [16]
    bait Elbing K (2006) [3]
    Co-fractionation
    bait Elbing K (2006) [16]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     REG1
  • PZF240
  • HEX2
  • SPP43
  • YDR028C
    		•  The BioGRID Database Seperator Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative regulation of glucose-repressible genes
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    hit Elbing K (2006) [16]
    hit Gavin AC (2006) [7592]
    bait Collins SR (2007) [9064]
    Affinity Capture-Western
    hit Nath N (2003) [6]
    hit Sanz P (2000) [3]
    Two-hybrid
    bait Ludin K (1998) [2]
    hit Sanz P (2000) [3]
    PCA
    bait Tarassov K (2008) [2616]
    Synthetic Rescue
    bait Vyas VK (2003) [7]
    Phenotypic Suppression
    bait Entian KD (1982) [2]
    bait Pasula S (2007) [1]
    Positive Genetic
    bait Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIP2
  • SPM2
  • YGL208W
    		•  The BioGRID Database Seperator One of three beta subunits of the Snf1 serine/threonine protein kinase complex involved in the response to glucose starvation; null mutants exhibit accelerated aging; N-myristoylprotein localized to the cytoplasm and the plasma membrane
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    bait/hit Ho Y (2002) [3666]
    hit Lo WS (2005) [5]
    hit Krogan NJ (2006) [7079]
    bait/hit Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    Two-hybrid
    hit Uetz P (2000) [875]
    bait Jiang R (1997) [9]
    bait Yu H (2008) [1778]
    Affinity Capture-Western
    hit Yang X (1994) [3]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIP4
  • YJL089W
    		•  The BioGRID Database Seperator C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Vincent O (1999) [5]
    Two-hybrid
    bait/hit Vincent O (2001) [8]
    bait/hit Vincent O (1999) [5]
    hit Lesage P (1996) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNF1
  • CAT1
  • PAS14
  • HAF3
  • YDR477W
    		•  The BioGRID Database Seperator AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis
    Gene Ontology: [View List]
    Co-crystal Structure
    hit Nayak V (2006) [3]
    Reconstituted Complex
    hit Nayak V (2006) [3]
    Affinity Capture-Western
    hit Nayak V (2006) [3]
    Biochemical Activity
    hit Nath N (2003) [6]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTK1
  • YKL139W
    		•  The BioGRID Database Seperator Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing
    Gene Ontology: [View List]
    Two-hybrid
    bait Van Driessche B (2005) [4]
    Affinity Capture-Western
    hit Van Driessche B (2005) [4]
    Phenotypic Enhancement
    bait Van Driessche B (2005) [4]
    Synthetic Growth Defect
    bait Van Driessche B (2005) [4]
    Negative Genetic
    hit Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NRG1
  • YDR043C
    		•  The BioGRID Database Seperator Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Vyas VK (2001) [5]
    Synthetic Rescue
    hit Vyas VK (2001) [5]
    hit Zhou H (2001) [7]
    hit Kuchin S (2002) [3]
    hit Ye T (2008) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIN4
  • GAL22
  • SDI3
  • RYE1
  • YNL236W
    		•  The BioGRID Database Seperator Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; contributes to both postive and negative transcriptional regulation; dispensible for basal transcription
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kuchin S (2000) [6]
    Two-hybrid
    hit Kuchin S (2000) [6]
    Synthetic Rescue
    hit Carlson M (1984) [8]
    Negative Genetic
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSN3
  • NUT7
  • GIG2
  • CDK8
  • YPL042C
    		•  The BioGRID Database Seperator Cyclin-dependent protein kinase, component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kuchin S (2000) [6]
    Two-hybrid
    hit Kuchin S (2000) [6]
    Synthetic Rescue
    hit Carlson M (1984) [8]
    Positive Genetic
    bait Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSN8
  • UME3
  • NUT9
  • RYE2
  • YNL025C
    		•  The BioGRID Database Seperator Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression and telomere maintenance
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kuchin S (2000) [6]
    Two-hybrid
    hit Kuchin S (2000) [6]
    Synthetic Rescue
    hit Carlson M (1984) [8]
    Positive Genetic
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NRG2
  • YBR066C
    		•  The BioGRID Database Seperator Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Vyas VK (2001) [5]
    Two-hybrid
    hit Vyas VK (2001) [5]
    Synthetic Rescue
    hit Vyas VK (2001) [5]
    hit Kuchin S (2002) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GIS4
  • YML006C
    		•  The BioGRID Database Seperator CAAX box containing protein of unknown function, proposed to be involved in the RAS/cAMP signaling pathway
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    Affinity Capture-Western
    bait La Rue J (2005) [5]
    Dosage Rescue
    hit Balciunas D (1999) [21]
    Synthetic Growth Defect
    hit Balciunas D (1999) [21]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HSF1
  • EXA3
  • MAS3
  • YGL073W
    		•  The BioGRID Database Seperator Trimeric heat shock transcription factor, activates multiple genes in response to stresses that include hyperthermia; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; posttranslationally regulated
    Gene Ontology: [View List]
    Two-hybrid
    bait Hahn JS (2004) [3]
    Biochemical Activity
    hit Hahn JS (2004) [3]
    hit Lee P (2008) [6]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STD1
  • SFS3
  • MSN3
  • YOR047C
    		•  The BioGRID Database Seperator Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Hubbard EJ (1994) [6]
    Two-hybrid
    bait/hit Hubbard EJ (1994) [6]
    bait Kuchin S (2003) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GLN3
  • YER040W
    		•  The BioGRID Database Seperator Transcriptional activator of genes regulated by nitrogen catabolite repression (NCR), localization and activity regulated by quality of nitrogen source
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Bertram PG (2002) [3]
    Two-hybrid
    hit Bertram PG (2002) [3]
    Biochemical Activity
    hit Bertram PG (2002) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ADR1
  • YDR216W
    		•  The BioGRID Database Seperator Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization
    Gene Ontology: [View List]
    Co-localization
    bait Young ET (2002) [1]
    Synthetic Rescue
    bait Denis CL (1984) [3]
    bait Denis CL (1986) [1]
    Dosage Rescue
    hit Denis CL (1987) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDE2
  • SRA5
  • YOR360C
    		•  The BioGRID Database Seperator High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon
    Gene Ontology: [View List]
    Dosage Rescue
    hit Wang Z (2001) [17]
    hit Balciunas D (1999) [21]
    hit Hubbard EJ (1992) [4]
    Synthetic Growth Defect
    bait/hit Balciunas D (1999) [21]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GET1
  • MDM39
  • YGL020C
    		•  The BioGRID Database Seperator Subunit of the GET complex; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance
    Gene Ontology: [View List]
    Synthetic Growth Defect
    bait Pan X (2006) [5331]
    Negative Genetic
    bait Collins SR (2007) [14430]
    hit Fiedler D (2009) [4053]
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MIG3
  • YER028C
    		•  The BioGRID Database Seperator Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes
    Gene Ontology: [View List]
    Biochemical Activity
    hit Dubacq C (2004) [9]
    Dosage Lethality
    hit Dubacq C (2004) [9]
    Synthetic Rescue
    hit Dubacq C (2004) [9]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RDS2
  • YPL133C
    		•  The BioGRID Database Seperator Zinc cluster transcriptional activator involved in conferring resistance to ketoconazole
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    bait Soontorngun N (2007) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIP3
  • YNL257C
    		•  The BioGRID Database Seperator Protein that activates transcription through interaction with DNA-bound Snf1p, C-terminal region has a putative leucine zipper motif; potential Cdc28p substrate
    Gene Ontology: [View List]
    Two-hybrid
    hit Lesage P (1994) [1]
    hit Yang X (1992) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSB1
  • YG101
  • YDL229W
    		•  The BioGRID Database Seperator Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in folding of newly-made polypeptide chains; member of the HSP70 family; interacts with phosphatase subunit Reg1p
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Elbing K (2006) [16]
    bait/hit Gong Y (2009) [1420]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIP5
  • YMR140W
    		•  The BioGRID Database Seperator Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and the Snf1p kinase
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Sanz P (2000) [4]
    Two-hybrid
    hit Sanz P (2000) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBI4
  • SCD2
  • UB14
  • YLL039C
    		•  The BioGRID Database Seperator Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    hit Elbing K (2006) [16]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GCN5
  • SWI9
  • ADA4
  • YGR252W
    		•  The BioGRID Database Seperator Histone acetyltransferase, acetylates N-terminal lysines on histones H2B and H3; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily
    Gene Ontology: [View List]
    Biochemical Activity
    hit Liu Y (2005) [4]
    Reconstituted Complex
    hit Liu Y (2005) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PHO85
  • LDB15
  • YPL031C
    		•  The BioGRID Database Seperator Cyclin-dependent kinase, with ten cyclin partners; involved in environmental stress response; in phosphate-rich conditions, Pho85p-Pho80p complex phosphorylates Pho4p which in turn represses PHO5
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Timblin BK (1996) [2]
    Synthetic Rescue
    hit Wang Z (2001) [1]
    hit Huang D (1996) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GET2
  • RMD7
  • HUR2
  • YER083C
    		•  The BioGRID Database Seperator Subunit of the GET complex; required for meiotic nuclear division and for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion; may be involved in cell wall function
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Pan X (2006) [5331]
    Negative Genetic
    bait Collins SR (2007) [14430]
    hit Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ROX3
  • NUT3
  • MED19
  • SSN7
  • YBL093C
    		•  The BioGRID Database Seperator Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme
    Gene Ontology: [View List]
    Dosage Rescue
    hit Song W (1996) [5]
    Synthetic Rescue
    hit Carlson M (1984) [8]
    Negative Genetic
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAL4
  • GAL81
  • YPL248C
    		•  The BioGRID Database Seperator DNA-binding transcription factor required for the activation of the GAL genes in response to galactose; repressed by Gal80p and activated by Gal3p
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Lo WS (2005) [5]
    Negative Genetic
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HXK2
  • SCI2
  • HEX1
  • HKB
  • YGL253W
    		•  The BioGRID Database Seperator Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Ahuatzi D (2007) [3]
    Negative Genetic
    hit Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MSN2
  • YMR037C
    		•  The BioGRID Database Seperator Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
    Gene Ontology: [View List]
    Biochemical Activity
    hit De Wever V (2005) [2]
    Dosage Rescue
    hit Estruch F (1993) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DBF2
  • YGR092W
    		•  The BioGRID Database Seperator Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Graumann J (2004) [478]
    Positive Genetic
    hit Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FUS3
  • DAC2
  • YBL016W
    		•  The BioGRID Database Seperator Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation
    Gene Ontology: [View List]
    Two-hybrid
    bait Sharan R (2005) [19]
    Positive Genetic
    bait Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HHT1
  • SIN2
  • BUR5
  • YBR010W
    		•  The BioGRID Database Seperator One of two identical histone H3 proteins (see also HHT2); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation
    Gene Ontology: [View List]
    Biochemical Activity
    hit Lo WS (2001) [2]
    Dosage Rescue
    hit Shirra MK (2005) [6]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PFK2
  • YMR205C
    		•  The BioGRID Database Seperator Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    Synthetic Rescue
    hit Huang D (1997) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC2
  • YNL272C
    		•  The BioGRID Database Seperator Guanyl-nucleotide exchange factor for the small G-protein Sec4p, located on cytoplasmic vesicles; essential for post-Golgi vesicle transport
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    Dosage Rescue
    bait Elbert M (2005) [30]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BUD14
  • YAR014C
    		•  The BioGRID Database Seperator Protein involved in bud-site selection, Bud14p-Glc7p complex functions as a cortical regulator of dynein; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    Negative Genetic
    bait Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIT4
  • LGN4
  • YDL047W
    		•  The BioGRID Database Seperator Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
    Gene Ontology: [View List]
    Synthetic Rescue
    hit Shirra MK (2005) [6]
    Positive Genetic
    bait Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CYC8
  • CRT8
  • SSN6
  • YBR112C
    		•  The BioGRID Database Seperator General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters
    Gene Ontology: [View List]
    Synthetic Rescue
    hit Neigeborn L (1984) [4]
    hit Carlson M (1984) [8]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FKS1
  • CWH53
  • GSC1
  • PBR1
  • YLR342W
    		•  The BioGRID Database Seperator Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Tong AH (2004) [3873]
    bait Lesage G (2004) [191]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ATG1
  • CVT10
  • APG1
  • AUT3
  • YGL180W
    		•  The BioGRID Database Seperator Protein serine/threonine kinase, required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for pre-autophagosome formation; forms a complex with Atg13p and Atg17p
    Gene Ontology: [View List]
    Dosage Rescue
    hit Wang Z (2001) [17]
    Positive Genetic
    bait Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CAT8
  • DIL1
  • MSP8
  • YMR280C
    		•  The BioGRID Database Seperator Zinc cluster transcriptional activator necessary for derepression of a variety of genes under non-fermentative growth conditions, active after diauxic shift, binds carbon source responsive elements
    Gene Ontology: [View List]
    Dosage Rescue
    hit Proft M (1995) [1]
    hit Hedges D (1995) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSN2
  • SRB9
  • NUT8
  • MED13
  • YDR443C
    		•  The BioGRID Database Seperator Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for stable association of Srb10p-Srb11p kinase; essential for transcriptional regulation
    Gene Ontology: [View List]
    Dosage Rescue
    hit Song W (1996) [5]
    Synthetic Rescue
    hit Carlson M (1984) [8]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GSF2
  • ECM6
  • YML048W
    		•  The BioGRID Database Seperator ER localized integral membrane protein that may promote secretion of certain hexose transporters, including Gal2p; involved in glucose-dependent repression
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Sherwood PW (1997) [1]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TUP1
  • CRT4
  • UMR7
  • FLK1
  • YCR084C
    		•  The BioGRID Database Seperator General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes
    Gene Ontology: [View List]
    Synthetic Rescue
    hit Williams FE (1990) [1]
    Phenotypic Suppression
    hit Neigeborn L (1987) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ELM1
  • LDB9
  • YKL048C
    		•  The BioGRID Database Seperator Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis; required for the regulation of other kinases; forms part of the bud neck ring
    Gene Ontology: [View List]
    Phenotypic Suppression
    bait Sutherland CM (2003) [4]
    Negative Genetic
    hit Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BUB1
  • YGR188C
    		•  The BioGRID Database Seperator Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the checkpoint mechanism required to prevent cell cycle progression into anaphase in the presence of spindle damage, associates with centromere DNA via Skp1p
    Gene Ontology: [View List]
    Positive Genetic
    bait Collins SR (2007) [14430]
    hit Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARO1
  • YDR127W
    		•  The BioGRID Database Seperator Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids
    Gene Ontology: [View List]
    Negative Genetic
    hit Collins SR (2007) [14430]
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CNB1
  • YCN2
  • CRV1
  • YKL190W
    		•  The BioGRID Database Seperator Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is encoded by CNA1 and/or CMP1
    Gene Ontology: [View List]
    Negative Genetic
    bait Fiedler D (2009) [4053]
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTC1
  • CWH47
  • KCS2
  • TPD1
  • YDL006W
    		•  The BioGRID Database Seperator Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p; mutation delays mitochondrial inheritance; deletion reveals defects in precursor tRNA splicing, sporulation and cell separation
    Gene Ontology: [View List]
    Positive Genetic
    hit Fiedler D (2009) [4053]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ENA1
  • PMR2
  • HOR6
  • YDR040C
    		•  The BioGRID Database Seperator P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance
    Gene Ontology: [View List]
    Dosage Rescue
    hit Ye T (2006) [6]
    Synthetic Rescue
    hit Ye T (2008) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SLX9
  • YGR081C
    		•  The BioGRID Database Seperator Protein required for pre-rRNA processing; associated with the 90S pre-ribosome and 43S small ribosomal subunit precursor; interacts with U3 snoRNA; deletion mutant has synthetic fitness defect with an sgs1 deletion mutant
    Gene Ontology: [View List]
    Positive Genetic
    hit Fiedler D (2009) [4053]
    Negative Genetic
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNT1
  • YCR033W
    		•  The BioGRID Database Seperator Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein
    Gene Ontology: [View List]
    Negative Genetic
    hit Collins SR (2007) [14430]
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ELP2
  • TOT2
  • YGR200C
    		•  The BioGRID Database Seperator Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; target of Kluyveromyces lactis zymocin
    Gene Ontology: [View List]
    Negative Genetic
    hit Fiedler D (2009) [4053]
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SAC1
  • RSD1
  • YKL212W
    		•  The BioGRID Database Seperator Phosphatidylinositol (PI) phosphatase, involved in hydrolysis of PI 3-phosphate, PI 4-phosphate and PI 3,5-bisphosphate to PI; membrane protein localizes to ER and Golgi; involved in protein trafficking, secretion and inositol metabolism
    Gene Ontology: [View List]
    Negative Genetic
    hit Fiedler D (2009) [4053]
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YPT6
  • YLR262C
    		•  The BioGRID Database Seperator GTPase, Ras-like GTP binding protein involved in the secretory pathway, required for fusion of endosome-derived vesicles with the late Golgi, maturation of the vacuolar carboxypeptidase Y; has similarity to the human GTPase, Rab6
    Gene Ontology: [View List]
    Negative Genetic
    bait Collins SR (2007) [14430]
    hit Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RIC1
  • YLR039C
    		•  The BioGRID Database Seperator Protein involved in retrograde transport to the cis-Golgi network; forms heterodimer with Rgp1p that acts as a GTP exchange factor for Ypt6p; involved in transcription of rRNA and ribosomal protein genes
    Gene Ontology: [View List]
    Negative Genetic
    bait Collins SR (2007) [14430]
    hit Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MCK1
  • YPK1
  • YNL307C
    		•  The BioGRID Database Seperator Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family
    Gene Ontology: [View List]
    Negative Genetic
    bait Collins SR (2007) [14430]
    hit Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRA2
  • CCS1
  • GLC4
  • YOL081W
    		•  The BioGRID Database Seperator GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin
    Gene Ontology: [View List]
    Negative Genetic
    bait Collins SR (2007) [14430]
    hit Costanzo M (2010) [68487]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD6
  • UBC2
  • PSO8
  • YGL058W
    		•  The BioGRID Database Seperator Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (with Rad18p), sporulation, telomere silencing, and ubiquitin-mediated N-end rule protein degradation (with Ubr1p)
    Gene Ontology: [View List]
    Synthetic Growth Defect
    bait Pan X (2006) [5331]
    Negative Genetic
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PGD1
  • MED3
  • HRS1
  • YGL025C
    		•  The BioGRID Database Seperator Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor
    Gene Ontology: [View List]
    Negative Genetic
    bait Collins SR (2007) [14430]
    Synthetic Lethality
    bait Dettmann A (2010) [11]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC22
  • TSL26
  • SLY2
  • YLR268W
    		•  The BioGRID Database Seperator R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi complex; involved in anterograde and retrograde transport between the ER and Golgi; synaptobrevin homolog
    Gene Ontology: [View List]
    Negative Genetic
    bait Collins SR (2007) [14430]
    hit Fiedler D (2009) [4053]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPN2
  • SEN3
  • YIL075C
    		•  The BioGRID Database Seperator Subunit of the 26S proteasome, substrate of the N-acetyltransferase Nat1p
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LEO1
  • YOR123C
    		•  The BioGRID Database Seperator Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone methylation
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YMR102C
  • YMR102C
    		•  The BioGRID Database Seperator Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBP6
  • YFR010W
    		•  The BioGRID Database Seperator Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; deletion causes hypersensitivity to cycloheximide and other toxic compounds
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ISA1
  • YLL027W
    		•  The BioGRID Database Seperator Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PHO91
  • YNR013C
    		•  The BioGRID Database Seperator Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RUD3
  • GRP1
  • YOR216C
    		•  The BioGRID Database Seperator Golgi matrix protein involved in the structural organization of the cis-Golgi; interacts genetically with COG3 and USO1
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DRE2
  • YKR071C
    		•  The BioGRID Database Seperator Protein of unknown function; mutation displays synthetic lethal interaction with the pol3-13 allele of CDC2
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPA34
  • YJL148W
    		•  The BioGRID Database Seperator RNA polymerase I subunit A34.5
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LAC1
  • DGT1
  • YKL008C
    		•  The BioGRID Database Seperator Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lag1p
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPL8A
  • MAK7
  • YHL033C
    		•  The BioGRID Database Seperator Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Bp and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STM1
  • MPT4
  • YLR150W
    		•  The BioGRID Database Seperator Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HAS1
  • YMR290C
    		•  The BioGRID Database Seperator ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RRP15
  • YPR143W
    		•  The BioGRID Database Seperator Nucleolar protein, constituent of pre-60S ribosomal particles; required for processing of the 27S pre-rRNA at the A2 site to yield 5.8S and 25S rRNA
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SPT16
  • CDC68
  • SSF1
  • YGL207W
    		•  The BioGRID Database Seperator Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ROD1
  • YOR018W
    		•  The BioGRID Database Seperator Membrane protein; overexpression confers resistance to the GST substrate o-dinitrobenzene as well as to zinc and calcium; contains 2 PY motifs, which are required for Rod1p interaction with Rsp5p, a hect-type ubiquitin ligase
    Gene Ontology: [View List]
    Biochemical Activity
    hit Shinoda J (2007) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     At4g16360
  • FCAALL.163
  • DL4210W
  • At4g16360
    		•  The BioGRID Database Seperator AMP-activated protein kinase
    Gene Ontology: [View List]
    Two-hybrid
    bait Bouly JP (1999) [10]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNF4
  • ATSNF4
  • F7G19.11
  • PUTATIVE ...
  • At1g09020
    		•  The BioGRID Database Seperator SNF4 (HOMOLOG OF YEAST SUCROSE NONFERMENTING 4); protein kinase activator
    Gene Ontology: [View List]
    Two-hybrid
    hit Kleinow T (2000) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PFK27
  • YOL136C
    		•  The BioGRID Database Seperator 6-phosphofructo-2-kinase, catalyzes synthesis of fructose-2,6-bisphosphate; inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, expression induced by glucose and sucrose, transcriptional regulation involves protein kinase A
    Gene Ontology: [View List]
    Biochemical Activity
    hit Benanti JA (2007) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     At5g21170
  • T10F18.200
  • T10F18_200
  • At5g21170
    		•  The BioGRID Database Seperator 5'-AMP-activated protein kinase beta-2 subunit, putative
    Gene Ontology: [View List]
    Two-hybrid
    bait Bouly JP (1999) [10]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRL1
  • FCAALL.40
  • PLEIOTROP...
  • DL3990W
  • At4g15900
    		•  The BioGRID Database Seperator PRL1 (PLEIOTROPIC REGULATORY LOCUS 1); basal transcription repressor/ nucleotide binding / protein binding
    Gene Ontology: [View List]
    Two-hybrid
    hit Bhalerao RP (1999) [8]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PEX13
  • PAS20
  • YLR191W
    		•  The BioGRID Database Seperator Integral peroxisomal membrane required for the translocation of peroxisomal matrix proteins, interacts with the PTS1 signal recognition factor Pex5p and the PTS2 signal recognition factor Pex7p, forms a complex with Pex14p and Pex17p
    Gene Ontology: [View List]
    Two-hybrid
    bait Tonikian R (2009) [751]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC5
  • PKX2
  • MSD2
  • YMR001C
    		•  The BioGRID Database Seperator Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bud neck, nucleus and SPBs; has multiple functions in mitosis and cytokinesis through phosphorylation of substrates; may be a Cdc28p substrate
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Matos J (2008) [53]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NUF2
  • YOL069W
    		•  The BioGRID Database Seperator Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering
    Gene Ontology: [View List]
    Two-hybrid
    bait Wong J (2007) [604]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APC4
  • YDR118W
    		•  The BioGRID Database Seperator Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
    Gene Ontology: [View List]
    Two-hybrid
    bait Wong J (2007) [604]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LHP1
  • LAH1
  • YLA1
  • YDL051W
    		•  The BioGRID Database Seperator RNA binding protein required for maturation of tRNA and snRNA precursors; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BUL2
  • YML111W
    		•  The BioGRID Database Seperator Component of the Rsp5p E3-ubiquitin ligase complex, involved in intracellular amino acid permease sorting, functions in heat shock element mediated gene expression, essential for growth in stress conditions, functional homolog of BUL1
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SCH9
  • KOM1
  • YHR205W
    		•  The BioGRID Database Seperator Protein kinase involved in transcriptional activation of osmostress-responsive genes; regulates G1 progression, cAPK activity, nitrogen activation of the FGM pathway; involved in life span regulation; homologous to mammalian Akt/PKB
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HOS4
  • YIL112W
    		•  The BioGRID Database Seperator Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CNS1
  • YBR155W
    		•  The BioGRID Database Seperator TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70) and stimulates the ATPase activity of SSA1, ts mutants reduce Hsp82p function while over expression suppresses the phenotypes of an HSP82 ts allele and a cpr7 deletion
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YKL121W
  • YKL121W
    		•  The BioGRID Database Seperator Putative protein of unknown function
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SBE22
  • YHR103W
    		•  The BioGRID Database Seperator Protein involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; involved in bud growth
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BFR1
  • YOR198C
    		•  The BioGRID Database Seperator Component of mRNP complexes associated with polyribosomes; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MRPL4
  • YLR439W
    		•  The BioGRID Database Seperator Mitochondrial ribosomal protein of the large subunit
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YKL023W
  • YKL023W
    		•  The BioGRID Database Seperator Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SHS1
  • SEP7
  • YDL225W
    		•  The BioGRID Database Seperator One of five related septins (Cdc3p, Cdc10p, Cdc11p, Cdc12p, Shs1p) that form a cortical filamentous collar at the mother-bud neck which is necessary for normal morphogenesis and cytokinesis
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC7
  • YDR170C
    		•  The BioGRID Database Seperator Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TPO3
  • YPR156C
    		•  The BioGRID Database Seperator Polyamine transport protein specific for spermine; localizes to the plasma membrane; member of the major facilitator superfamily
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARF1
  • YDL192W
    		•  The BioGRID Database Seperator ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RCK1
  • YGL158W
    		•  The BioGRID Database Seperator Protein kinase involved in the response to oxidative stress; identified as suppressor of S. pombe cell cycle checkpoint mutations
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRB1
  • CVT1
  • YEL060C
    		•  The BioGRID Database Seperator Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NSG1
  • YHR133C
    		•  The BioGRID Database Seperator Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TOM71
  • TOM72
  • YHR117W
    		•  The BioGRID Database Seperator Mitochondrial outer membrane protein with similarity to Tom70p; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBP10
  • DOT4
  • YNL186W
    		•  The BioGRID Database Seperator Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; primarily located in the nucleus
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRM1
  • YDR120C
    		•  The BioGRID Database Seperator tRNA methyltransferase, localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VHS3
  • YOR29-05
  • YOR054C
    		•  The BioGRID Database Seperator Functionally redundant (see also SIS2) inhibitory subunit of Ppz1p, a PP1c-related ser/thr protein phosphatase Z isoform; synthetically lethal with sis2; putative phosphopantothenoylcysteine decarboxylase involved in coenzyme A biosynthesis
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MFT1
  • MFT52
  • YML062C
    		•  The BioGRID Database Seperator Subunit of the THO complex, which is a nuclear complex comprised of Hpr1p, Mft1p, Rlr1p, and Thp2p, that is involved in transcription elongation and mitotic recombination; involved in telomere maintenance
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BDF2
  • YDL070W
    		•  The BioGRID Database Seperator Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YHR214C-C
  • YHR214C-C
    		•  The BioGRID Database Seperator Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YPK2
  • YKR2
  • YMR104C
    		•  The BioGRID Database Seperator Protein kinase with similarityto serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SIS1
  • YNL007C
    		•  The BioGRID Database Seperator Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; not functionally redundant with Ydj1p due to due to substrate specificity; shares similarity with bacterial DnaJ proteins
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YBL055C
  • YBL055C
    		•  The BioGRID Database Seperator 3'-->5' exonuclease and endonuclease with a possible role in apoptosis; has similarity to mammalian and C. elegans apoptotic nucleases
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BMH1
  • APR6
  • YER177W
    		•  The BioGRID Database Seperator 14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Elbing K (2006) [16]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GLC7
  • CID1
  • DIS2
  • YER133W
    		•  The BioGRID Database Seperator Catalytic subunit of type 1 serine/threonine protein phosphatase, involved in many processes including glycogen metabolism, sporulation, and mitosis; interacts with multiple regulatory subunits; predominantly isolated with Sds22p
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PHO4
  • YFR034C
    		•  The BioGRID Database Seperator Basic helix-loop-helix (bHLH) transcription factor of the myc-family; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD30
  • DBH1
  • YDR419W
    		•  The BioGRID Database Seperator DNA polymerase eta, involved in the predominantly error-free bypass replication of DNA lesions, catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers; homolog of human POLH and bacterial DinB proteins
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BMH2
  • SCD3
  • YDR099W
    		•  The BioGRID Database Seperator 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Elbing K (2006) [16]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSA2
  • YG102
  • YLL024C
    		•  The BioGRID Database Seperator ATP binding protein involved in protein folding and vacuolar import of proteins; member of heat shock protein 70 (HSP70) family; associated with the chaperonin-containing T-complex; present in the cytoplasm, vacuolar membrane and cell wall
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Elbing K (2006) [16]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSA1
  • YG100
  • YAL005C
    		•  The BioGRID Database Seperator ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport; member of heat shock protein 70 (HSP70) family; forms a chaperone complex with Ydj1p; localized to the nucleus, cytoplasm, and cell wall
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Elbing K (2006) [16]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSB2
  • YG103
  • YNL209W
    		•  The BioGRID Database Seperator Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in the folding of newly-synthesized polypeptide chains; member of the HSP70 family; homolog of SSB1
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Elbing K (2006) [16]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SDS22
  • EGP1
  • YKL193C
    		•  The BioGRID Database Seperator Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine phosphatase (PP1), functions positively with Glc7p to promote dephosphorylation of nuclear substrates required for chromosome transmission during mitosis
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Graumann J (2004) [478]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SMT3
  • YDR510W
    		•  The BioGRID Database Seperator Ubiquitin-like protein of the SUMO family, conjugated to lysine residues of target proteins; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Hannich JT (2005) [162]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MGS1
  • YNL218W
    		•  The BioGRID Database Seperator Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome; interacts functionally with DNA polymerase delta; homolog of human Werner helicase interacting protein (WHIP)
    Gene Ontology: [View List]
    Two-hybrid
    hit Uetz P (2000) [875]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NOP53
  • YPL146C
    		•  The BioGRID Database Seperator Nucleolar protein; involved in biogenesis of the 60S subunit of the ribosome; interacts with rRNA processing factors Cbf5p and Nop2p; null mutant is viable but growth is severely impaired
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HCR1
  • YLR192C
    		•  The BioGRID Database Seperator Dual function protein involved in translation initiation as a substoichiometric component of eukaryotic translation initiation factor 3 (eIF3) and required for processing of 20S pre-rRNA; binds to eIF3 subunits Rpg1p and Prt1p and 18S rRNA
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NTR2
  • YKR022C
    		•  The BioGRID Database Seperator Essential protein that forms a dimer with Ntr1p; also forms a trimer, with Ntr2p and the DExD/H-box RNA helicase Prp43p, that is involved in spliceosome disassembly
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FOX2
  • POX2
  • YKR009C
    		•  The BioGRID Database Seperator Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PIB2
  • YGL023C
    		•  The BioGRID Database Seperator Protein binding phosphatidylinositol 3-phosphate, involved in telomere-proximal repression of gene expression; similar to Fab1 and Vps27
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YMR086W
  • YMR086W
    		•  The BioGRID Database Seperator Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; cAMP represses YMR086W expression
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ho Y (2002) [3666]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSF2
  • YDR312W
    		•  The BioGRID Database Seperator Protein required for ribosomal large subunit maturation, functionally redundant with Ssf1p; member of the Brix family
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDS1
  • YDR113C
    		•  The BioGRID Database Seperator Securin that inhibits anaphase by binding separin Esp1p, also blocks cyclin destruction and mitotic exit, essential for cell cycle arrest in mitosis in the presence of DNA damage or aberrant mitotic spindles; also present in meiotic nuclei
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARV1
  • YLR242C
    		•  The BioGRID Database Seperator Protein required for normal intracellular sterol distribution and for sphingolipid metabolism; similar to Nup120p and C. elegans R05H5.5 protein
    Gene Ontology: [View List]
    Biochemical Activity
    hit Ptacek J (2005) [4183]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ROG3
  • YFR022W
    		•  The BioGRID Database Seperator Protein that binds to Rsp5p, which is a hect-type ubiquitin ligase, via its 2 PY motifs; has similarity to Rod1p; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant
    Gene Ontology: [View List]