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BioGRID | Network Layout for HEM12 for Saccharomyces cerevisiae
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HEM12

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: HEM6, YDR047W
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PIXEL
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Description: Hem12p|Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; activity inhibited by Cu2+, Zn2+, Fe2+, Fe3+ and sulfhydryl-specific reagents; protein coding
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PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [GeneDB]  [Germ Online]  [SGD]  
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PIXEL
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Gene Ontology: 4 total GO mappings for this record. [view list]
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Download interactions associated with HEM12

HEM12 was identified with 5 protein interactions and 2 genetic interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 HEM12
  • HEM6
  • YDR047W
    		•  The BioGRID Database Seperator Hem12p|Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; activity inhibited by Cu2+, Zn2+, Fe2+, Fe3+ and sulfhydryl-specific reagents; protein coding
    Gene Ontology: [View List]
    PCA
    hit Tarassov K (2008)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SEC27
  • YGL137W
    		•  The BioGRID Database Seperator Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP|Sec27p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CFH
  • CFHL3
  • FH
  • FHL1
  • EG3075
    		•  The BioGRID Database Seperator H factor 1 (complement)|H factor 2 (complement)|age-related maculopathy susceptibility 1|beta-1-H-globulin|beta-1H|complement factor H, isoform b|factor H|factor H-like 1; complement factor H
    Gene Ontology: [View List]
    Far Western
    hit Poltermann S (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RSP5
  • MDP1
  • MUT2
  • NPI1
  • YER125W
    		•  The BioGRID Database Seperator Rsp5p|Ubiquitin-protein ligase involved in ubiquitin-mediated protein degradation; functions in multivesicular body sorting, heat shock response and ubiquitylation of arrested RNAPII; contains a hect (homologous to E6-AP carboxyl terminus) domain; protein coding
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Gupta R (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRT1
  • CDC63
  • DNA26
  • YOR361C
    		•  The BioGRID Database Seperator Prt1p|Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SUI3
  • YPL237W
    		•  The BioGRID Database Seperator Beta subunit of the translation initiation factor eIF2, involved in the identification of the start codon; proposed to be involved in mRNA binding|Sui3p; protein coding
    Gene Ontology: [View List]
    Synthetic Rescue
    hit Gora M (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SUI1
  • MOF2
  • RFR1
  • YNL244C
    		•  The BioGRID Database Seperator Sui1p|Translation initiation factor eIF1; component of a complex involved in recognition of the initiator codon; modulates translation accuracy at the initiation phase; protein coding
    Gene Ontology: [View List]
    Synthetic Rescue
    hit Gora M (2000)
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    The BioGRID Database Seperator
    The BioGRID Database Seperator
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