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BioGRID | Network Layout for SLX4 for Saccharomyces cerevisiae
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SLX4

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: YLR135W
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Slx4p|Subunit of a complex, with Slx1p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p; protein coding
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [GeneDB]  [Germ Online]  [SGD]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 7 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with SLX4

SLX4 was identified with 23 protein interactions and 49 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code
Role Source [Interactions]
The BioGRID Database Seperator
 SLX1
  • YBR228W
    		•  The BioGRID Database Seperator Slx1p|Subunit of a complex, with Slx4p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait Ito T (2001) [785]
    bait Uetz P (2000) [875]
    hit Li F (2008) [12]
    Affinity Capture-Western
    bait/hit Mullen JR (2001) [21]
    Co-purification
    bait Fricke WM (2003) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD1
  • LPB9
  • YPL022W
    		•  The BioGRID Database Seperator Rad1p|Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human XPF protein; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait Ito T (2001) [785]
    hit Li F (2008) [12]
    bait Yu H (2008) [1778]
    Affinity Capture-Western
    hit Flott S (2007) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RTT107
  • ESC4
  • YHR154W
    		•  The BioGRID Database Seperator Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition|Rtt107p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Roberts TM (2006) [17]
    Affinity Capture-Western
    bait/hit Roberts TM (2006) [17]
    Reconstituted Complex
    bait Roberts TM (2006) [17]
    Two-hybrid
    bait Zappulla DC (2006) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SGS1
  • YMR190C
    		•  The BioGRID Database Seperator Nucleolar DNA helicase of the RecQ family involved in maintenance of genome integrity, regulates chromosome synapsis and meiotic crossing over; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes|Sgs1p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Tong AH (2001) [338]
    bait Kaliraman V (2002) [1]
    bait Mullen JR (2001) [21]
    bait Pan X (2004) [323]
    bait/hit Pan X (2006) [5331]
    Phenotypic Enhancement
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DIA2
  • YOR29-31
  • YOR080W
    		•  The BioGRID Database Seperator Dia2p|Origin-binding F-box protein that forms an SCF ubiquitin ligase complex with Skp1p and Cdc53p; plays a role in DNA replication, involved in invasive and pseudohyphal growth; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    bait Pan X (2006) [5331]
    Synthetic Lethality
    hit Pan X (2006) [5331]
    bait Blake D (2006) [61]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RMI1
  • NCE4
  • YPL024W
    		•  The BioGRID Database Seperator Involved in response to DNA damage; null mutants have increased rates of recombination and delayed S phase; interacts physically and genetically with Sgs1p (RecQ family member) and Top3p (topoisomerase III)|Rmi1p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Mullen JR (2005) [15]
    bait Chang M (2005) [17]
    Phenotypic Enhancement
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     REV3
  • PSO1
  • YPL167C
    		•  The BioGRID Database Seperator Catalytic subunit of DNA polymerase zeta, which is involved in DNA repair and translesion synthesis; required for mutagenesis induced by DNA damage|Rev3p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Flott S (2007) [7]
    Phenotypic Suppression
    hit Flott S (2007) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ESC2
  • YDR363W
    		•  The BioGRID Database Seperator Esc2p|Protein involved in mating-type locus silencing, interacts with Sir2p; probably functions to recruit or stabilize Sir proteins; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Tong AH (2004) [3873]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TOP3
  • EDR1
  • YLR234W
    		•  The BioGRID Database Seperator DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially, involved in telomere stability and regulation of mitotic recombination|Top3p; protein coding
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Mullen JR (2001) [21]
    Phenotypic Enhancement
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YEF3
  • TEF3
  • YLR249W
    		•  The BioGRID Database Seperator Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing EF-1 alpha from the ribosomal complex; contains two ABC cassettes; binds and hydrolyses ATP|Yef3p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CPR1
  • CPH1
  • CYP1
  • YDR155C
    		•  The BioGRID Database Seperator Cpr1p|Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSZ1
  • PDR13
  • YHR064C
    		•  The BioGRID Database Seperator Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP|Ssz1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BMH2
  • SCD3
  • YDR099W
    		•  The BioGRID Database Seperator 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling|Bmh2p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AHP1
  • YLR109W
    		•  The BioGRID Database Seperator Ahp1p|Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TDH1
  • GLD3
  • YJL052W
    		•  The BioGRID Database Seperator Glyceraldehyde-3-phosphate dehydrogenase, isozyme 1, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall|Tdh1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GUS1
  • GSN1
  • YGL245W
    		•  The BioGRID Database Seperator Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm|Gus1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD10
  • YML095C
    		•  The BioGRID Database Seperator Rad10p|Single-stranded DNA endonuclease (with Rad1p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human ERCC1 protein; protein coding
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Flott S (2007) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC27
  • APC3
  • SNB1
  • YBL084C
    		•  The BioGRID Database Seperator Cdc27p|Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait Wong J (2007) [604]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HXK1
  • YFR053C
    		•  The BioGRID Database Seperator Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p|Hxk1p; protein coding
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YMR293C
  • YMR293C
    		•  The BioGRID Database Seperator Putative protein similar to bacterial glutamyl-tRNA amidotransferases; may be involved in aerobic respiration; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies|Ymr293cp; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF14
  • ANC1
  • SWP29
  • TAF30
  • YPL129W
    		•  The BioGRID Database Seperator Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes, involved in RNA polymerase II transcription initiation and in chromatin modification; contains a YEATS domain|Taf14p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YMC1
  • YPR058W
    		•  The BioGRID Database Seperator Mitochondrial protein, putative inner membrane transporter with a role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; has similarity with Ymc2p|Ymc1p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YLL033W
  • IRC19
    		•  The BioGRID Database Seperator Irc19p|Putative protein of unknown function; YLL033W is not an essential gene but mutant is defective in spore formation; null mutant displays increased levels of spontaneous Rad52 foci; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YGR046W
  • TAM41
  • MMP37
    		•  The BioGRID Database Seperator Mitochondrial protein involved in protein import into the mitochondrial matrix; maintains the functional integrity of the TIM23 protein translocator complex; viability of null mutant is strain-dependent; mRNA is targeted to the bud|Tam41p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRI1
  • YIR008C
    		•  The BioGRID Database Seperator Pri1p|Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YLR193C
  • UPS1
    		•  The BioGRID Database Seperator Mitochondrial intermembrane space protein that regulates alternative processing and sorting of Mgm1p and other proteins; required for normal mitochondrial morphology; ortholog of human PRELI|Ups1p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APN1
  • YKL114C
    		•  The BioGRID Database Seperator Apn1p|Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Flott S (2007) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAG1
  • MMS5
  • YER142C
    		•  The BioGRID Database Seperator 3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired|Mag1p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Flott S (2007) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YDR065W
  • YDR065W
    		•  The BioGRID Database Seperator Protein of unknown function, required for vacuolar acidification; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies|Ydr065wp; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPC40
  • RPC5
  • YPR110C
    		•  The BioGRID Database Seperator RNA polymerase subunit, common to RNA polymerase I and III|Rpc40p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    bait Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MGM101
  • MGM9
  • YJR144W
    		•  The BioGRID Database Seperator Mgm101p|Protein involved in mitochondrial genome maintenance; component of the mitochondrial nucleoid, required for the repair of oxidative mtDNA damage; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBC4
  • YBR082C
    		•  The BioGRID Database Seperator Ubc4p|Ubiquitin-conjugating enzyme (E2), mediates degradation of short-lived and abnormal proteins; interacts with E3-CaM in ubiquitinating calmodulin; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SAC3
  • LEP1
  • YDR159W
    		•  The BioGRID Database Seperator Nuclear pore-associated protein, forms a complex with Thp1p that is involved in transcription and in mRNA export from the nucleus|Sac3p; protein coding
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SPT4
  • YGR063C
    		•  The BioGRID Database Seperator Protein that forms a complex with Spt5p and mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing; in addition, Spt4p is involved in kinetochore function and gene silencing|Spt4p; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Collins SR (2007) [14430]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MMS22
  • SLM2
  • YLR320W
    		•  The BioGRID Database Seperator Mms22p|Protein involved in resistance to ionizing radiation; acts with Mms1p in a repair pathway that may be involved in resolving replication intermediates or preventing the damage caused by blocked replication forks; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FKS1
  • CND1
  • CWH53
  • ETG1
  • YLR342W
    		•  The BioGRID Database Seperator Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling|Fks1p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LSM7
  • YNL147W
    		•  The BioGRID Database Seperator Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA|Lsm7p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DBF2
  • YGR092W
    		•  The BioGRID Database Seperator Dbf2p|Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTK3
  • YML112W
    		•  The BioGRID Database Seperator Ctk3p|Gamma subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TDP1
  • YBR223C
    		•  The BioGRID Database Seperator Tdp1p|Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3'-phosphotyrosyl bonds to generate 3'-phosphate DNA and tyrosine, involved in the repair of DNA lesions created by topoisomerase I; protein coding
    Gene Ontology: [View List]
    Phenotypic Enhancement
    bait Deng C (2005) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CTK1
  • YKL139W
    		•  The BioGRID Database Seperator Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing|Ctk1p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MSC1
  • YML128C
    		•  The BioGRID Database Seperator Msc1p|Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria and is phosphorylated; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MTG1
  • YMR097C
    		•  The BioGRID Database Seperator Mtg1p|Peripheral GTPase of the mitochondrial inner membrane, essential for respiratory competence, likely functions in assembly of the large ribosomal subunit, has homologs in plants and animals; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SCP160
  • YJL080C
    		•  The BioGRID Database Seperator Essential RNA-binding G protein effector of mating response pathway, mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins|Scp160p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VPS34
  • END12
  • PEP15
  • VPL7
  • YLR240W
    		•  The BioGRID Database Seperator Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p|Vps34p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD51
  • MUT5
  • YER095W
    		•  The BioGRID Database Seperator Rad51p|Strand exchange protein, forms a helical filament with DNA that searches for homology; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; homolog of Dmc1p and bacterial RecA protein; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PEP5
  • END1
  • VAM1
  • VPL9
  • YMR231W
    		•  The BioGRID Database Seperator Component of CORVET tethering complex; peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis; interacts with Pep7p|Pep5p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NPT1
  • YOR209C
    		•  The BioGRID Database Seperator Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus|Npt1p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NUP120
  • RAT2
  • YKL057C
    		•  The BioGRID Database Seperator Nup120p|Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for even distribution of NPCs around the nuclear envelope, involved in establishment of a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VRP1
  • END5
  • MDP2
  • YLR337W
  • YLR337C
    		•  The BioGRID Database Seperator Proline-rich actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP)|Vrp1p; protein coding
    Gene Ontology: [View List]
    Synthetic Growth Defect
    hit Pan X (2006) [5331]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    terms and conditions - privacy policy - Osprey Network Visualization System
    BioGRID: A General Repository for Interaction Datasets.
    Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
    Nucleic Acids Res. Jan 1;34:D535-9.