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BioGRID | Network Layout for TEN1 for Saccharomyces cerevisiae
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TEN1

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: YLR010C
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Protein that regulates telomeric length; protects telomeric ends in a complex with Cdc13p and Stn1p
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [UniprotKB] | [SGD] | [Entrez Gene] | [GeneDB]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 7 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with TEN1

TEN1 was identified with 14 protein interactions and 7 genetic interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code
Role Source [Interactions]
The BioGRID Database Seperator
 STN1
  • YDR082W
    		•  The BioGRID Database Seperator Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action with completion of lagging strand synthesis, and in a regulatory step required for telomere capping
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Grandin N (2001) [8]
    bait Gao H (2007) [1]
    hit Qian W (2009) [6]
    Two-hybrid
    hit Grandin N (2001) [8]
    bait Petreaca RC (2006) [3]
    bait Petreaca RC (2007) [9]
    hit Yu H (2008) [1778]
    hit Puglisi A (2008) [6]
    bait Puglisi A (2008) [7]
    hit Xu L (2009) [7]
    Dosage Rescue
    bait Grandin N (2001) [8]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC13
  • EST4
  • YDL220C
    		•  The BioGRID Database Seperator Single stranded DNA-binding protein found at TG1-3 telomere G-tails; regulates telomere replication through recruitment of specific sub-complexes, but the essential function is telomere capping
    Gene Ontology: [View List]
    Two-hybrid
    hit Grandin N (2001) [8]
    hit Xu L (2009) [7]
    Affinity Capture-Western
    bait/hit Qian W (2009) [6]
    Reconstituted Complex
    bait Qian W (2009) [6]
    Dosage Rescue
    bait Grandin N (2001) [8]
    Synthetic Lethality
    hit Xu L (2009) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     POL1
  • HPR3
  • CDC17
  • CRT5
  • YNL102W
    		•  The BioGRID Database Seperator Catalytic subunit of the DNA polymerase I alpha-primase complex, required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis
    Gene Ontology: [View List]
    Synthetic Growth Defect
    bait Xu L (2009) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EXO1
  • DHS1
  • YOR033C
    		•  The BioGRID Database Seperator 5'-3' exonuclease and flap-endonuclease involved in recombination, double-strand break repair and DNA mismatch repair; member of the Rad2p nuclease family, with conserved N and I nuclease domains
    Gene Ontology: [View List]
    Synthetic Rescue
    hit Xu L (2009) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC12
  • CLA10
  • PSL7
  • YHR107C
    		•  The BioGRID Database Seperator Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Davierwala AP (2005) [564]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EST2
  • YLR318W
    		•  The BioGRID Database Seperator Reverse transcriptase subunit of the telomerase holoenzyme, essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia
    Gene Ontology: [View List]
    Synthetic Lethality
    hit Xu L (2009) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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    BioGRID: A General Repository for Interaction Datasets.
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    Nucleic Acids Res. Jan 1;34:D535-9.