The BioGRID Database Seperator
Search
Organism:

BioGRID | Network Layout for TAF2 for Saccharomyces cerevisiae
[JPG] [PNG] [SVG]		 The BioGRID Database Seperator

TAF2

 Saccharomyces cerevisiae
The BioGRID Database Seperator
Aliases: TAF150, TSM1, YCR042C
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [UniprotKB] | [SGD] | [Entrez Gene] | [GeneDB]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 6 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with TAF2

TAF2 was identified with 71 protein interactions and 2 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code
Role Source [Interactions]
The BioGRID Database Seperator
 TAF1
  • TAF130
  • TAF145
  • YGR274C
    		•  The BioGRID Database Seperator TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation, has histone acetyltransferase activity, involved in promoter binding and G1/S progression
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    bait/hit Sanders SL (2002) [483]
    bait/hit Sanders SL (2000) [94]
    hit Gavin AC (2006) [7592]
    Affinity Capture-Western
    bait Durso RJ (2001) [16]
    bait Garbett KA (2007) [15]
    bait Mischerikow N (2009) [32]
    Co-purification
    bait Sanders SL (2002) [14]
    bait Papai G (2009) [13]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SPT15
  • TBP1
  • BTF1
  • YER148W
    		•  The BioGRID Database Seperator TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    bait/hit Sanders SL (2000) [94]
    Affinity Capture-Western
    bait Sanders SL (2000) [94]
    bait/hit Poon D (1993) [9]
    bait/hit Poon D (1994) [13]
    bait/hit Poon D (1995) [11]
    bait Klebanow ER (1996) [13]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF14
  • SWP29
  • TFG3
  • ANC1
  • YPL129W
    		•  The BioGRID Database Seperator Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes, involved in RNA polymerase II transcription initiation and in chromatin modification; contains a YEATS domain
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    bait/hit Sanders SL (2002) [483]
    hit Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    Two-hybrid
    bait Kabani M (2005) [12]
    Affinity Capture-Western
    hit Kabani M (2005) [12]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF8
  • TAF65
  • YML114C
    		•  The BioGRID Database Seperator TFIID subunit (65 kDa), involved in RNA polymerase II transcription initiation
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    bait/hit Sanders SL (2002) [483]
    bait Krogan NJ (2006) [7079]
    bait/hit Gavin AC (2006) [7592]
    hit Collins SR (2007) [9064]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF11
  • TAF40
  • YML015C
    		•  The BioGRID Database Seperator TFIID subunit (40 kDa), involved in RNA polymerase II transcription initiation, similar to histone H3 with atypical histone fold motif of Spt3-like transcription factors
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    bait/hit Sanders SL (2002) [483]
    hit Gavin AC (2006) [7592]
    Affinity Capture-Western
    hit Klebanow ER (1997) [6]
    bait Takahata S (2004) [16]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF6
  • TAF60
  • YGL112C
    		•  The BioGRID Database Seperator Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    bait/hit Sanders SL (2002) [483]
    hit Gavin AC (2006) [7592]
    Two-hybrid
    hit Yatherajam G (2003) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF5
  • TAF90
  • YBR198C
    		•  The BioGRID Database Seperator Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    bait/hit Sanders SL (2002) [483]
    hit Gavin AC (2006) [7592]
    Affinity Capture-Western
    bait Durso RJ (2001) [16]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF10
  • TAF25
  • TAF23
  • YDR167W
    		•  The BioGRID Database Seperator Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    Affinity Capture-Western
    bait Kirchner J (2001) [18]
    hit Klebanow ER (1996) [13]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF13
  • TAF19
  • FUN81
  • YML098W
    		•  The BioGRID Database Seperator TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    bait Auty R (2004) [19]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TEF4
  • EFC1
  • YKL081W
    		•  The BioGRID Database Seperator Translation elongation factor EF-1 gamma
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Gavin AC (2002) [3400]
    hit Gavin AC (2006) [7592]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF12
  • TAF61
  • TAF68
  • YDR145W
    		•  The BioGRID Database Seperator Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF7
  • TAF67
  • YMR227C
    		•  The BioGRID Database Seperator TFIID subunit (67 kDa), involved in RNA polymerase II transcription initiation
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF4
  • TAF48
  • MPT1
  • TSG2
  • YMR005W
    		•  The BioGRID Database Seperator TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p substrate
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF3
  • TAF47
  • YPL011C
    		•  The BioGRID Database Seperator TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ESC1
  • YMR219W
    		•  The BioGRID Database Seperator Protein localized to the nuclear periphery, involved in telomeric silencing; interacts with PAD4-domain of Sir4p
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ROX1
  • REO1
  • YPR065W
    		•  The BioGRID Database Seperator Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Krogan NJ (2006) [7079]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBI4
  • SCD2
  • UB14
  • YLL039C
    		•  The BioGRID Database Seperator Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Peng J (2003) [1092]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TFB4
  • YPR056W
    		•  The BioGRID Database Seperator Subunit of TFIIH complex, involved in transcription initiation, similar to 34 kDa subunit of human TFIIH; interacts with Ssl1p
    Gene Ontology: [View List]
    Co-purification
    bait Wade PA (1996) [24]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSN3
  • NUT7
  • GIG2
  • CDK8
  • YPL042C
    		•  The BioGRID Database Seperator Cyclin-dependent protein kinase, component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression
    Gene Ontology: [View List]
    Biochemical Activity
    bait Liu Y (2004) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GAL11
  • SPT13
  • ABE1
  • MED15
  • YOL051W
    		•  The BioGRID Database Seperator Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Sakurai H (1996) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YSH1
  • BRR5
  • YLR277C
    		•  The BioGRID Database Seperator Putative endoribonuclease, subunit of the mRNA cleavage and polyadenylation specificity complex required for 3' processing of mRNAs
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     REF2
  • YDR195W
    		•  The BioGRID Database Seperator RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation, and in snoRNA maturation; part of holo-CPF subcomplex APT, which associates with 3'-ends of snoRNA- and mRNA-encoding genes
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GCR1
  • LPF10
  • YPL075W
    		•  The BioGRID Database Seperator Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LEU3
  • YLR451W
    		•  The BioGRID Database Seperator Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; positively regulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FIP1
  • YJR093C
    		•  The BioGRID Database Seperator Subunit of cleavage polyadenylation factor (CPF), interacts directly with poly(A) polymerase (Pap1p) to regulate its activity
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CFT2
  • YDH1
  • YLR115W
    		•  The BioGRID Database Seperator Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein.
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CFT1
  • YHH1
  • YDR301W
    		•  The BioGRID Database Seperator RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in poly(A) site recognition and required for both pre-mRNA cleavage and polyadenylation, 51% sequence similarity with mammalian AAUAA-binding subunit of CPSF
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF9
  • TAF17
  • YMR236W
    		•  The BioGRID Database Seperator Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait/hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MPE1
  • YKL059C
    		•  The BioGRID Database Seperator Essential conserved subunit of CPF (cleavage and polyadenylation factor), plays a role in 3' end formation of mRNA via the specific cleavage and polyadenylation of pre-mRNA, contains a putative RNA-binding zinc knuckle motif
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TAF2
  • TAF150
  • TSM1
  • YCR042C
    		•  The BioGRID Database Seperator TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MSN2
  • YMR037C
    		•  The BioGRID Database Seperator Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SSU72
  • YNL222W
    		•  The BioGRID Database Seperator Transcription/RNA-processing factor that associates with TFIIB and cleavage/polyadenylation factor Pta1p; exhibits phosphatase activity on serine-5 of the RNA polymerase II C-terminal domain; affects start site selection in vivo
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTA1
  • FUN39
  • YAL043C
    		•  The BioGRID Database Seperator Subunit of holo-CPF, a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAP1
  • YKR002W
    		•  The BioGRID Database Seperator Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Sanders SL (2002) [483]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ASF1
  • CIA1
  • YJL115W
    		•  The BioGRID Database Seperator Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed
    Gene Ontology: [View List]
    Dosage Rescue
    bait Chimura T (2002) [13]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC12
  • CLA10
  • PSL7
  • YHR107C
    		•  The BioGRID Database Seperator Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
    Gene Ontology: [View List]
    Synthetic Lethality
    bait Davierwala AP (2005) [564]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    terms and conditions - privacy policy - Osprey Network Visualization System
    BioGRID: A General Repository for Interaction Datasets.
    Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
    Nucleic Acids Res. Jan 1;34:D535-9.