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DEDD2
Homo sapiens
Aliases:
FLAME-3, EG162989
Description:
death effector domain-containing DNA binding protein 2|death effector domain-containing DNA binding protein 2; death effector domain containing 2
Links:
[Entrez-Gene]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
11 total GO annotations for this record.
[view list]
Function
Process
Component
•
protein binding
(
IPI
)
•
receptor signaling comple ...
(
NAS
)
•
cellular homeostasis
(
NAS
)
•
activation of pro-apoptot ...
(
NAS
)
•
intracellular signaling c ...
(
NAS
)
•
negative regulation of tr ...
(
NAS
)
•
induction of apoptosis vi ...
(
IMP
)
•
rRNA catabolic process
(
NAS
)
•
RNA processing
(
NAS
)
•
apoptotic nuclear changes
(
IDA
)
•
nucleolus
(
IDA
)
Download interactions associated with DEDD2
DEDD2 was identified with
19
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
DEDD
CASP8IP1
DEDD1
DEFT
EG9191
death effector domain-containing|death effector domain-containing protein; death effector domain containing
Gene Ontology:
[View List]
Invivo
bait
Zhan Y (2002)
bait
Alcivar A (2003)
Invitro
bait/hit
Zhan Y (2002)
bait/hit
Alcivar A (2003)
CFLAR
CASH
CASP8AP1
CLARP
EG8837
FADD-like anti-apoptotic molecule; Inhibitor of FLICE; Caspase-related inducer of apoptosis; Caspase homolog; Caspase-like apoptosis regulatory protein|usurpin beta; CASP8 and FADD-like apoptosis regulator
Gene Ontology:
[View List]
Invivo
hit
Zhan Y (2002)
Invitro
bait/hit
Zhan Y (2002)
Reconstituted Complex
hit
Roth W (2002)
Affinity Capture-Western
bait
Roth W (2002)
CASP8
FLICE
MACH
MCH5
EG841
FADD-homologous ICE/CED-3-like protease|MACH-alpha-1/2/3 protein|MACH-beta-1/2/3/4 protein|Mch5 isoform alpha|caspase 8|caspase 8, apoptosis-related cysteine protease|cysteine protease|procaspase-8; caspase 8, apoptosis-related cysteine peptidase
Gene Ontology:
[View List]
Invitro
bait/hit
Alcivar A (2003)
bait/hit
Zhan Y (2002)
Invivo
bait
Zhan Y (2002)
bait
Alcivar A (2003)
GTF3C3
TFIIIC102
TFIIICgamma
TFiiiC2-102
EG9330
general transcription factor IIIC, polypeptide 3 (102kD)|transcription factor IIIC, 102 kD; general transcription factor IIIC, polypeptide 3, 102kDa
Gene Ontology:
[View List]
Invivo
bait/hit
Zhan Y (2002)
Invitro
bait/hit
Zhan Y (2002)
Two-hybrid
bait
Zhan Y (2002)
DEDD2
FLAME-3
EG162989
death effector domain-containing DNA binding protein 2|death effector domain-containing DNA binding protein 2; death effector domain containing 2
Gene Ontology:
[View List]
Invitro
bait/hit
Zhan Y (2002)
bait/hit
Alcivar A (2003)
CASP10
ALPS2
FLICE2
MCH4
EG843
FADD-like ICE2|Fas-associated death domain protein|ICE-like apoptotic protease 4|apoptotic protease MCH-4|caspase 10|caspase 10, apoptosis-related cysteine protease|interleukin-1B-converting enzyme 2; caspase 10, apoptosis-related cysteine peptidase
Gene Ontology:
[View List]
Invitro
bait/hit
Alcivar A (2003)
Invivo
bait
Alcivar A (2003)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.