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SHC3
Homo sapiens
Aliases:
N-Shc, NSHC, SHCC, EG53358
Description:
neuronal Shc|src homology 2 domain containing transforming protein C3|src homology 2 domain-containing transforming protein C3; SHC (Src homology 2 domain containing) transforming protein 3
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
7 total GO annotations for this record.
[view list]
Function
Process
Component
•
signal transducer activit ...
(
TAS
)
•
protein binding
(
IPI
)
•
intracellular signaling c ...
(
NAS
)
•
central nervous system de ...
(
TAS
)
•
epidermal growth factor r ...
(
TAS
)
•
cellular component unknow ...
(
ND
)
•
cellular_component
(
ND
)
Download interactions associated with SHC3
SHC3 was identified with
6
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
RICS
GC-GAP
GRIT
KIAA0712
EG9743
GAB-associated CDC42|RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling|brain-specific Rho GTP-ase-activating protein|rac GTPase activating protein; Rho GTPase-activating protein
Gene Ontology:
[View List]
Affinity Capture-Western
bait
Nakamura T (2002)
Reconstituted Complex
hit
Nakamura T (2002)
ALK
CD246
TFG/ALK
EG238
ALK tyrosine kinase receptor|CD246 antigen|TRK-fused gene-anaplastic lymphoma kinase fusion protein|anaplastic lymphoma kinase Ki-1; anaplastic lymphoma kinase (Ki-1)
Gene Ontology:
[View List]
Affinity Capture-Western
bait
Miyake I (2002)
NTRK2
GP145-TrkB
TRKB
EG4915
BDNF/NT-3 growth factors receptor|tyrosine kinase receptor B; neurotrophic tyrosine kinase, receptor, type 2
Gene Ontology:
[View List]
Invivo
hit
Nakamura T (1998)
NTRK1
MTC
TRK
TRK1
EG4914
Oncogene TRK|high affinity nerve growth factor receptor|tyrosine kinase receptor A; neurotrophic tyrosine kinase, receptor, type 1
Gene Ontology:
[View List]
Invivo
hit
Nakamura T (1998)
EGFR
ERBB
ERBB1
mENA
EG1956
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Gene Ontology:
[View List]
Invivo
hit
Nakamura T (1998)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.