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LDLRAP1
Homo sapiens
Aliases:
ARH, ARH2, DKFZp586D0624, FHCB1, FHCB2, MGC34705, ARH1, RP11-70P17.2
Description:
LDL receptor adaptor protein|autosomal recessive hypercholesterolemia protein; low density lipoprotein receptor adaptor protein 1
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
15 total GO mappings for this record.
[view list]
Function
Process
Component
•
protein binding, bridging
(
NAS
)
•
transport accessory prote ...
(
NAS
)
•
receptor signaling comple ...
(
IMP
)
•
phosphotyrosine binding
(
IDA
)
•
clathrin binding
(
IDA
)
•
protein C-terminus bindin ...
(
IPI
)
•
regulation of protein bin ...
(
IMP
)
•
cholesterol metabolic pro ...
(
NAS
)
•
positive regulation of re ...
(
IMP
)
•
cholesterol homeostasis
(
NAS
)
•
early endosome
(
IDA
)
•
cytosol
(
IDA
)
•
AP-2 adaptor complex
(
IPI
)
•
AP-1 adaptor complex
(
IDA
)
•
basal plasma membrane
(
IDA
)
Download interactions associated with LDLRAP1
LDLRAP1 was identified with
8
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
LRP2
gp330
DBS
EG4036
Heymann nephritis antigen homolog|calcium sensor protein|megalin; low density lipoprotein-related protein 2
Gene Ontology:
[View List]
Two-hybrid
bait
Nagai M (2003)
Reconstituted Complex
bait
Nagai M (2003)
Affinity Capture-Western
hit
Nagai M (2003)
TFAP2A
AP-2
AP2TF
TFAP2
EG7020
activating enhancer-binding protein 2 alpha|transcription factor AP-2 alpha|transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha); transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Gene Ontology:
[View List]
Invitro
hit
He G (2002)
Affinity Capture-MS
bait
Rual JF (2005)
AP2B1
ADTB2
AP2-BETA
CLAPB1
EG163
adaptin, beta 2 (beta)|clathrin assembly protein complex 2 beta large chain|clathrin-associated/assembly/adaptor protein, large, beta 1|plasma membrane adaptor HA2/AP2 adaptin beta subunit; adaptor-related protein complex 2, beta 1 subunit
Gene Ontology:
[View List]
Two-hybrid
bait
Rual JF (2005)
LDLR
FH
FHC
EG3949
low density lipoprotein receptor (familial hypercholesterolemia); LDL receptor|low density lipoprotein receptor
Gene Ontology:
[View List]
Invitro
hit
He G (2002)
CLTC
CHC17
CLH-17
CLTCL2
EG1213
clathrin heavy chain 1|clathrin, heavy polypeptide (Hc)|clathrin, heavy polypeptide-like 2; clathrin, heavy chain (Hc)
Gene Ontology:
[View List]
Invitro
hit
He G (2002)
Copyright © 2007,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.