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NCSTN
Homo sapiens
Aliases:
APH2, KIAA0253, RP11-517F10.1, EG23385
Description:
ATAG1874|anterior pharynx-defective 2; nicastrin
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
10 total GO mappings for this record.
[view list]
Function
Process
Component
•
protein binding
(
IPI
)
•
Notch receptor processing
(
TAS
)
•
protein processing
(
IDA
)
•
membrane protein ectodoma ...
(
IDA
)
•
proteolysis
(
NAS
)
•
positive regulation of ca ...
(
IDA
)
•
amyloid precursor protein ...
(
TAS
)
•
Golgi apparatus
(
IDA
)
•
endoplasmic reticulum
(
IDA
)
•
integral to plasma membra ...
(
IDA
)
Download interactions associated with NCSTN
NCSTN was identified with
18
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
APH1A
6530402N0...
APH-1A
CGI-78
EG51107
anterior pharynx defective 1 homolog A (C. elegans); anterior pharynx defective 1 homolog A
Gene Ontology:
[View List]
Affinity Capture-Western
hit
Haffner C (2004)
bait/hit
Baulac S (2003)
bait
LaVoie MJ (2003)
bait/hit
Gu Y (2003)
bait/hit
Lee SF (2002)
Co-fractionation
bait
Gu Y (2003)
PSEN1
AD3
FAD
PS1
EG5663
presenilin 1 (Alzheimer disease 3); presenilin 1
Gene Ontology:
[View List]
Affinity Capture-Western
hit
Haffner C (2004)
bait/hit
Baulac S (2003)
bait/hit
Gu Y (2003)
hit
Lee SF (2002)
hit
Yu G (2000)
PSEN2
AD3L
AD4
PS2
EG5664
Alzheimer's disease 3-like|presenilin 2; presenilin 2 (Alzheimer disease 4)
Gene Ontology:
[View List]
Affinity Capture-Western
hit
Lee SF (2002)
hit
Yu G (2000)
PSENEN
MDS033
MSTP064
PEN2
EG55851
hematopoietic stem/progenitor cells protein MDS033|presenilin enhancer 2; presenilin enhancer 2 homolog (C. elegans)
Gene Ontology:
[View List]
Affinity Capture-Western
bait/hit
Baulac S (2003)
bait
Steiner H (2002)
BACE1
ASP2
BACE
HSPC104
EG23621
APP beta-secretase|aspartyl protease 2|beta-secretase|beta-site amyloid beta A4 precursor protein-cleaving enzyme|beta-site amyloid precursor protein cleaving enzyme|memapsin-2|membrane-associated aspartic protease 2|transmembrane aspartic proteinase Asp2; beta-site APP-cleaving enzyme 1
Gene Ontology:
[View List]
Invivo
bait
Hattori C (2002)
Invitro
bait
Hattori C (2002)
APP
AAA
ABETA
ABPP
EG351
A4 amyloid protein|amyloid beta A4 protein|amyloid-beta protein|beta-amyloid peptide|cerebral vascular amyloid peptide|protease nexin-II; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
Gene Ontology:
[View List]
Affinity Capture-Western
hit
Yu G (2000)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.