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BioGRID | Network Layout for CHEK2 for Homo sapiens
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CHEK2

 Homo sapiens
The BioGRID Database Seperator
Aliases: CDS1, CHK2, HuCds1, PP1425, RAD53, LFS2, RP11-436C9.1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: OTTHUMP00000028871|checkpoint-like protein CHK2|protein kinase CHK2|serine/threonine-protein kinase CHK2; CHK2 checkpoint homolog (S. pombe)
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 6 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with CHEK2

CHEK2 was identified with 19 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 MSH2
  • COCA1
  • FCC1
  • HNPCC
  • EG4436
    		•  The BioGRID Database Seperator mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli); mutS homolog 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Adamson AW (2005)
    hit Brown KD (2003)
    Reconstituted Complex
    hit Brown KD (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MUS81
  • FLJ21012
  • FLJ44872
  • EG80198
    		•  The BioGRID Database Seperator MUS81 endonuclease homolog (S. cerevisiae); MUS81 endonuclease homolog
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Chen XB (2001)
    Reconstituted Complex
    hit Chen XB (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLK3
  • CNK
  • FNK
  • PRK
  • RP11-269F...
    		•  The BioGRID Database Seperator FGF-inducible kinase|cytokine-inducible kinase|polo-like kinase 3|proliferation-related kinase; polo-like kinase 3 (Drosophila)
    Gene Ontology: [View List]
    Biochemical Activity
    bait Bahassi el M (2002)
    Affinity Capture-Western
    hit Bahassi el M (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLK1
  • PLK
  • STPK13
  • EG5347
    		•  The BioGRID Database Seperator cell cycle regulated protein kinase|polo (Drosophia)-like kinase|polo like kinase|polo-like kinase; polo-like kinase 1 (Drosophila)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Tsvetkov L (2003)
    Biochemical Activity
    bait Tsvetkov L (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MDC1
  • KIAA0170
  • NFBD1
  • DKFZp781A...
  • DAQB-47P1...
    		•  The BioGRID Database Seperator homologue to Drosophila photoreceptor protein calphotin|nuclear factor with BRCT domains 1; mediator of DNA damage checkpoint 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Lou Z (2003)
    Reconstituted Complex
    bait Lou Z (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BRCA1
  • BRCAI
  • IRIS
  • PSCP
  • EG672
    		•  The BioGRID Database Seperator BRCA1/BRCA2-containing complex, subunit 1|breast and ovarian cancer susceptibility protein 1; breast cancer 1, early onset
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Lee JS (2000)
    Affinity Capture-Western
    hit Lee JS (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAD50
  • RAD50-2
  • hRad50
  • EG10111
    		•  The BioGRID Database Seperator RAD50 homolog (S. cerevisiae); RAD50 homolog
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Matsuoka S (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TP53BP1
  • 53BP1
  • p202
  • MGC138366
  • EG7158
    		•  The BioGRID Database Seperator tumor protein 53-binding protein, 1|tumor protein p53 binding protein, 1|tumor protein p53-binding protein, 1; tumor protein p53 binding protein 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Matsuoka S (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VCP
  • IBMPFD
  • TERA
  • p97
  • EG7415
    		•  The BioGRID Database Seperator transitional endoplasmic reticulum ATPase|yeast Cdc48p homolog; valosin-containing protein
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Matsuoka S (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ASK
  • DBF4
  • DBF4A
  • CHIF
  • EG10926
    		•  The BioGRID Database Seperator activator of S phase kinase|chiffon homolog|zinc finger, DBF-type containing 1; DBF4 homolog (S. cerevisiae)
    Gene Ontology: [View List]
    Two-hybrid
    bait Duncker BP (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Pfs2
  • HSPC037
  • GINS2
  • PSF2
  • EG51659
    		•  The BioGRID Database Seperator DNA replication complex GINS protein PSF2; GINS complex subunit 2 (Psf2 homolog)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Matsuoka S (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BRCA2
  • FACD
  • FAD
  • FAD1
  • RP11-298P...
    		•  The BioGRID Database Seperator BRCA1/BRCA2-containing complex, subunit 2|OTTHUMP00000042401|breast and ovarian cancer susceptibility gene, early onset|breast cancer 2 tumor suppressor|breast cancer susceptibility protein BRCA2; breast cancer 2, early onset
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Matsuoka S (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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