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CASP8AP2
Homo sapiens
Aliases:
CED-4, FLASH, FLJ11208, KIAA1315, RIP25, EG9994
Description:
FLASH homolog RIP25|FLICE associated huge|human FLASH; CASP8 associated protein 2
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
Gene Ontology:
10 total GO mappings for this record.
[view list]
Function
Process
Component
•
death receptor binding
(
TAS
)
•
caspase activator activit ...
(
ISS
)
•
protein binding
(
IPI
)
•
transcription corepressor ...
(
IDA
)
•
signal transduction
(
TAS
)
•
induction of apoptosis vi ...
(
ISS
)
•
induction of apoptosis by ...
(
TAS
)
•
caspase activation
(
ISS
)
•
nucleus
(
IDA
)
•
cytoplasm
(
IDA
)
Download interactions associated with CASP8AP2
CASP8AP2 was identified with
6
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
TRAF2
MGC:45012
TRAP
TRAP3
EG7186
OTTHUMP00000064745|tumor necrosis factor type 2 receptor associated protein 3; TNF receptor-associated factor 2
Gene Ontology:
[View List]
Reconstituted Complex
bait
Choi YH (2001)
Affinity Capture-Western
hit
Choi YH (2001)
CASP8AP2
CED-4
FLASH
FLJ11208
EG9994
FLASH homolog RIP25|FLICE associated huge|human FLASH; CASP8 associated protein 2
Gene Ontology:
[View List]
Invivo
bait/hit
Imai Y (1999)
FADD
GIG3
MGC8528
MORT1
EG8772
Fas-associated via death domain|Fas-associating death domain-containing protein|Fas-associating protein with death domain|growth-inhibiting gene 3 protein|mediator of receptor-induced toxicity; Fas (TNFRSF6)-associated via death domain
Gene Ontology:
[View List]
Invivo
bait/hit
Imai Y (1999)
CASP8
FLICE
MACH
MCH5
EG841
FADD-homologous ICE/CED-3-like protease|MACH-alpha-1/2/3 protein|MACH-beta-1/2/3/4 protein|Mch5 isoform alpha|caspase 8|caspase 8, apoptosis-related cysteine protease|cysteine protease|procaspase-8; caspase 8, apoptosis-related cysteine peptidase
Gene Ontology:
[View List]
Invivo
bait/hit
Imai Y (1999)
FAS
ALPS1A
APO-1
APT1
EG355
APO-1 cell surface antigen|CD95 antigen|Fas antigen|OTTHUMP00000059646|apoptosis antigen 1|tumor necrosis factor receptor superfamily, member 6; Fas (TNF receptor superfamily, member 6)
Gene Ontology:
[View List]
Invivo
bait/hit
Imai Y (1999)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.