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BioGRID | Network Layout for HGS for Homo sapiens
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HGS

 Homo sapiens
The BioGRID Database Seperator
Aliases: HRS, ZFYVE8, EG9146
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: hepatocyte growth factor-regulated tyrosine kinase substrate; human growth factor-regulated tyrosine kinase substrate
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 10 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with HGS

HGS was identified with 48 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 NF2
  • ACN
  • BANF
  • SCH
  • EG4771
    		•  The BioGRID Database Seperator merlin|moesin-ezrin-radixin like|moesin-ezrin-radizin-like protein|neurofibromatosis type 2|neurofibromatosis-2|neurofibromin 2|neurofibromin 2 (bilateral acoustic neuroma)|schwannomerlin|schwannomin; neurofibromin 2 (merlin)
    Gene Ontology: [View List]
    Invivo
    bait Scoles DR (2000)
    Invitro
    bait Scoles DR (2000)
    Two-hybrid
    bait Scoles DR (2000)
    Reconstituted Complex
    hit Gutmann DH (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HAP1
  • HAP2
  • HIP5
  • HLP
  • EG9001
    		•  The BioGRID Database Seperator huntingtin-associated protein 1|huntingtin-associated protein 2|neuroan 1; huntingtin-associated protein 1 (neuroan 1)
    Gene Ontology: [View List]
    Two-hybrid
    bait Li Y (2002)
    Reconstituted Complex
    hit Li Y (2002)
    Affinity Capture-Western
    bait Li Y (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EPS15
  • AF-1P
  • AF1P
  • MLLT5
  • EG2060
    		•  The BioGRID Database Seperator epidermal growth factor receptor pathway substrate 15; ALL1 fused gene from chromosome 1
    Gene Ontology: [View List]
    Invivo
    bait Bache KG (2003)
    Reconstituted Complex
    bait Bean AJ (2000)
    Two-hybrid
    hit Bean AJ (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TSG101
  • TSG10
  • VPS23
  • EG7251
    		•  The BioGRID Database Seperator tumor susceptibility gene 101; tumor susceptibility protein
    Gene Ontology: [View List]
    Two-hybrid
    bait Rual JF (2005)
    bait Lu Q (2003)
    Affinity Capture-Western
    bait/hit Lu Q (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DLG4
  • PSD95
  • SAP90
  • EG1742
    		•  The BioGRID Database Seperator discs large homolog 4|postsynaptic density protein 95|synapse-associated protein 90; discs, large homolog 4 (Drosophila)
    Gene Ontology: [View List]
    Two-hybrid
    bait Chetkovich DM (2002)
    Affinity Capture-Western
    bait Chetkovich DM (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K7
  • TAK1
  • TGF1a
  • EG6885
    		•  The BioGRID Database Seperator TGF-beta activated kinase 1|transforming growth factor-beta-activated kinase 1; mitogen-activated protein kinase kinase kinase 7
    Gene Ontology: [View List]
    Invivo
    bait Sasaki Y (2001)
    Invitro
    bait Sasaki Y (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LYST
  • CHS
  • CHS1
  • EG1130
    		•  The BioGRID Database Seperator Chediak-Higashi syndrome 1|OTTHUMP00000059294|beige protein; lysosomal trafficking regulator
    Gene Ontology: [View List]
    Invitro
    bait Tchernev VT (2002)
    Two-hybrid
    bait Tchernev VT (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAM
  • STAM1
  • DKFZp686J...
  • EG8027
    		•  The BioGRID Database Seperator signal transducing adaptor molecule (SH3 domain and ITAM motif) 1; signal transducing adaptor molecule 1
    Gene Ontology: [View List]
    Two-hybrid
    bait Rual JF (2005)
    Affinity Capture-Western
    hit Asao H (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NEDD4
  • KIAA0093
  • MGC176705
  • EG4734
    		•  The BioGRID Database Seperator neural precursor cell expressed, developmentally down-regulated 4
    Gene Ontology: [View List]
    Invivo
    bait Katz M (2002)
    Invitro
    bait Katz M (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DAZAP2
  • KIAA0058
  • MGC14319
  • MGC766
  • EG9802
    		•  The BioGRID Database Seperator deleted in azoospermia associated protein 2; DAZ associated protein 2
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     C1orf190
  • FLJ25163
  • EG541468
    		•  The BioGRID Database Seperator chromosome 1 open reading frame 190; hypothetical protein LOC541468
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBE2I
  • C358B7.1
  • P18
  • UBC9
  • EG7329
    		•  The BioGRID Database Seperator SUMO-1-protein ligase|ubiquitin carrier protein|ubiquitin conjugating enzyme 9|ubiquitin-conjugating enzyme E2I|ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9)|ubiquitin-conjugating enzyme UbcE2A|ubiquitin-like protein SUMO-1 conjugating enzyme|ubiquitin-protein ligas...
    Gene Ontology: [View List]
    Two-hybrid
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FLJ32855
  • FLJ23168
  • MGC34145
  • CCDC33
  • EG80125
    		•  The BioGRID Database Seperator coiled-coil domain containing 33
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KIAA1446
  • BEGAIN
  • EG57596
    		•  The BioGRID Database Seperator brain-enriched guanylate kinase-associated homolog|brain-enriched guanylate kinase-associated protein|likely ortholog of rat brain-enriched guanylate kinase-associated protein; brain-enriched guanylate kinase-associated homolog (rat)
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBQLN1
  • DA41
  • DSK2
  • FLJ90054
  • EG29979
    		•  The BioGRID Database Seperator ubiquilin 1
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TADA2L
  • ADA2
  • FLJ12705
  • KL04P
  • EG6871
    		•  The BioGRID Database Seperator ADA2-like|transcriptional adaptor 2 (ADA2, yeast, homolog)-like|transcriptional adaptor 2 alpha|transcriptional adaptor 2-like; transcriptional adaptor 2 (ADA2 homolog, yeast)-like
    Gene Ontology: [View List]
    Two-hybrid
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LDOC1
  • BCUR1
  • Mar7
  • Mart7
  • EG23641
    		•  The BioGRID Database Seperator leucine zipper, down-regulated in cancer 1; breast cancer, up-regulated 1
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KRT18
  • CYK18
  • K18
  • EG3875
    		•  The BioGRID Database Seperator cell proliferation-inducing protein 46|cytokeratin 18; keratin 18
    Gene Ontology: [View List]
    Two-hybrid
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CRSP9
  • CRSP33
  • MED7
  • MGC12284
  • EG9443
    		•  The BioGRID Database Seperator cofactor required for Sp1 transcriptional activation, subunit 9 (33kD)|cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa; mediator complex subunit 7
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAM2
  • DKFZp564C...
  • Hbp
  • STAM2A
  • EG10254
    		•  The BioGRID Database Seperator STAM-like protein containing SH3 and ITAM domains 2|signal transducing adaptor molecule 2; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BAT8
  • C6orf30
  • G9A
  • NG36
  • DAQB-331I...
    		•  The BioGRID Database Seperator G9A histone methyltransferase|HLA-B associated transcript 8|ankyrin repeat-containing protein; euchromatic histone-lysine N-methyltransferase 2
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAK1
  • PAKalpha
  • MGC130000
  • MGC130001
  • EG5058
    		•  The BioGRID Database Seperator p21-activated kinase 1|p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
    Gene Ontology: [View List]
    Invivo
    bait Sasaki Y (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VPS37C
  • FLJ20847
  • EG55048
    		•  The BioGRID Database Seperator vacuolar protein sorting 37 homolog C (S. cerevisiae); vacuolar protein sorting 37C
    Gene Ontology: [View List]
    Two-hybrid
    bait Eastman SW (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNX1
  • HsT17379
  • MGC8664
  • SNX1A
  • EG6642
    		•  The BioGRID Database Seperator sorting nexin 1A; sorting nexin 1
    Gene Ontology: [View List]
    Invivo
    bait Chin LS (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SNAP25
  • FLJ23079
  • SNAP
  • SNAP-25
  • EG6616
    		•  The BioGRID Database Seperator resistance to inhibitors of cholinesterase 4 homolog|synaptosomal-associated protein 25; synaptosomal-associated protein, 25kDa
    Gene Ontology: [View List]
    Invivo
    bait Raiborg C (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PIK3R1
  • GRB1
  • p85-ALPHA
  • EG5295
    		•  The BioGRID Database Seperator phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)|phosphatidylinositol 3-kinase, regulatory, 1|phosphatidylinositol 3-kinase-associated p-85 alpha|phosphoinositide-3-kinase, regulatory subunit, polypeptide 1|phosphoinositide-3-kinase, regulatory subunit, polypeptide...
    Gene Ontology: [View List]
    Invitro
    bait Gillooly DJ (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EXOC7
  • 2-5-3p
  • EXO70
  • Exo70p
  • EG23265
    		•  The BioGRID Database Seperator exocyst complex component 7
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KRT19
  • CK19
  • K19
  • K1CS
  • EG3880
    		•  The BioGRID Database Seperator 40-kDa keratin intermediate filament|cytokeratin 19|keratin, type I cytoskeletal 19|keratin, type I, 40-kd; keratin 19
    Gene Ontology: [View List]
    Two-hybrid
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EXOC8
  • EXO84
  • Exo84p
  • SEC84
  • EG149371
    		•  The BioGRID Database Seperator OTTHUMP00000060156|exocyst complex 84-kDa subunit; exocyst complex component 8
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NMI
  • EG9111
    		•  The BioGRID Database Seperator N-myc and STAT interactor|N-myc interactor|N-myc-interactor; N-myc (and STAT) interactor
    Gene Ontology: [View List]
    Two-hybrid
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CLTC
  • CHC17
  • CLH-17
  • CLTCL2
  • EG1213
    		•  The BioGRID Database Seperator clathrin heavy chain 1|clathrin, heavy polypeptide (Hc)|clathrin, heavy polypeptide-like 2; clathrin, heavy chain (Hc)
    Gene Ontology: [View List]
    Two-hybrid
    bait Raiborg C (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     USHBP1
  • AIEBP
  • FLJ90681
  • MCC2
  • EG83878
    		•  The BioGRID Database Seperator Usher syndrome 1C binding protein 1; AIE-75 binding protein protein
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GKAP1
  • FKSG21
  • FLJ25469
  • GKAP42
  • EG80318
    		•  The BioGRID Database Seperator 4933400B15Rik|cGMP-dependent protein kinase anchoring protein 42kDa|protein kinase anchoring protein GKAP42; G kinase anchoring protein 1
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AD023
  • MGC45027
  • MIF4GD
  • MIFD
  • EG57409
    		•  The BioGRID Database Seperator SLBP-interacting protein 1; MIF4G domain containing
    Gene Ontology: [View List]
    Two-hybrid
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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