The BioGRID Database Seperator
Search
Organism:

BioGRID | Network Layout for CFLAR for Homo sapiens
[JPG] [PNG] [SVG]		 The BioGRID Database Seperator

CFLAR

 Homo sapiens
The BioGRID Database Seperator
Aliases: CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLIP, I-FLICE, MRIT, USURPIN, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, FLAME1, EG8837
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: FADD-like anti-apoptotic molecule; Inhibitor of FLICE; Caspase-related inducer of apoptosis; Caspase homolog; Caspase-like apoptosis regulatory protein|usurpin beta; CASP8 and FADD-like apoptosis regulator
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 6 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with CFLAR

CFLAR was identified with 43 protein interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 CASP8
  • FLICE
  • MACH
  • MCH5
  • EG841
    		•  The BioGRID Database Seperator FADD-homologous ICE/CED-3-like protease|MACH-alpha-1/2/3 protein|MACH-beta-1/2/3/4 protein|Mch5 isoform alpha|caspase 8|caspase 8, apoptosis-related cysteine protease|cysteine protease|procaspase-8; caspase 8, apoptosis-related cysteine peptidase
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Micheau O (2003)
    hit Shu HB (1997)
    bait Srinivasula SM (1997)
    hit Micheau O (2002)
    Two-hybrid
    hit Goltsev YV (1997)
    bait/hit Srinivasula SM (1997)
    Reconstituted Complex
    hit Srinivasula SM (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FADD
  • GIG3
  • MGC8528
  • MORT1
  • EG8772
    		•  The BioGRID Database Seperator Fas-associated via death domain|Fas-associating death domain-containing protein|Fas-associating protein with death domain|growth-inhibiting gene 3 protein|mediator of receptor-induced toxicity; Fas (TNFRSF6)-associated via death domain
    Gene Ontology: [View List]
    Invivo
    hit Zhan Y (2002)
    Invitro
    hit Zhan Y (2002)
    Two-hybrid
    hit Zhan Y (2002)
    bait/hit Srinivasula SM (1997)
    Affinity Capture-Western
    hit Shu HB (1997)
    bait/hit Srinivasula SM (1997)
    Reconstituted Complex
    bait/hit Srinivasula SM (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CASP10
  • ALPS2
  • FLICE2
  • MCH4
  • EG843
    		•  The BioGRID Database Seperator FADD-like ICE2|Fas-associated death domain protein|ICE-like apoptotic protease 4|apoptotic protease MCH-4|caspase 10|caspase 10, apoptosis-related cysteine protease|interleukin-1B-converting enzyme 2; caspase 10, apoptosis-related cysteine peptidase
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Micheau O (2003)
    bait Srinivasula SM (1997)
    Two-hybrid
    hit Goltsev YV (1997)
    bait/hit Srinivasula SM (1997)
    Reconstituted Complex
    hit Srinivasula SM (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DEDD2
  • FLAME-3
  • EG162989
    		•  The BioGRID Database Seperator death effector domain-containing DNA binding protein 2|death effector domain-containing DNA binding protein 2; death effector domain containing 2
    Gene Ontology: [View List]
    Invitro
    bait/hit Roth W (2002)
    bait/hit Zhan Y (2002)
    Invivo
    bait Zhan Y (2002)
    bait Roth W (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRAF2
  • MGC:45012
  • TRAP
  • TRAP3
  • EG7186
    		•  The BioGRID Database Seperator OTTHUMP00000064745|tumor necrosis factor type 2 receptor associated protein 3; TNF receptor-associated factor 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Shu HB (1997)
    bait/hit Kataoka T (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRAF1
  • EBI6
  • MGC:10353
  • EG7185
    		•  The BioGRID Database Seperator Epstein-Bar virus-induced protein 6; TNF receptor-associated factor 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Shu HB (1997)
    bait/hit Kataoka T (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FAS
  • ALPS1A
  • APO-1
  • APT1
  • EG355
    		•  The BioGRID Database Seperator APO-1 cell surface antigen|CD95 antigen|Fas antigen|OTTHUMP00000059646|apoptosis antigen 1|tumor necrosis factor receptor superfamily, member 6; Fas (TNF receptor superfamily, member 6)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Shu HB (1997)
    bait MacFarlane M (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNFRSF10B
  • DR5
  • KILLER
  • KILLER/DR5
  • EG8795
    		•  The BioGRID Database Seperator Fas-like protein|TNF-related apoptosis-inducing ligand receptor 2|TRAIL receptor 2|apoptosis inducing protein TRICK2A/2B|apoptosis inducing receptor TRAIL-R2|cytotoxic TRAIL receptor-2|death domain containing receptor for TRAIL/Apo-2L|death receptor 5|p53-regulated DNA damage-inducible cell...
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait MacFarlane M (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNFRSF10A
  • APO2
  • DR4
  • MGC9365
  • EG8797
    		•  The BioGRID Database Seperator TNF-related apoptosis inducing ligand receptor 1|cytotoxic TRAIL receptor|death receptor 4; tumor necrosis factor receptor superfamily, member 10a
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait MacFarlane M (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CARD4
  • NOD1
  • CLR7.1
  • NLRC1
  • EG10392
    		•  The BioGRID Database Seperator NLR family, CARD domain containing 1|caspase recruitment domain 4|caspase recruitment domain family, member 4|nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1; nucleotide-binding oligomerization domain containing 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Inohara N (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRAF3
  • CAP-1
  • CD40bp
  • CRAF1
  • EG7187
    		•  The BioGRID Database Seperator CD40 associated protein 1|CD40 binding protein|CD40 receptor associated factor 1|LMP1 associated protein; TNF receptor-associated factor 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kataoka T (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAF1
  • CRAF
  • Raf-1
  • c-Raf
  • EG5894
    		•  The BioGRID Database Seperator Oncogene RAF1|raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Kataoka T (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RIPK1
  • FLJ39204
  • RIP
  • RIP1
  • EG8737
    		•  The BioGRID Database Seperator receptor (TNFRSF)-interacting serine-threonine kinase 1; OTTHUMP00000039163|receptor interacting protein
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Kataoka T (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CFLAR
  • CASH
  • CASP8AP1
  • CLARP
  • EG8837
    		•  The BioGRID Database Seperator FADD-like anti-apoptotic molecule; Inhibitor of FLICE; Caspase-related inducer of apoptosis; Caspase homolog; Caspase-like apoptosis regulatory protein|usurpin beta; CASP8 and FADD-like apoptosis regulator
    Gene Ontology: [View List]
    Two-hybrid
    bait/hit Srinivasula SM (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IKBKB
  • IKK-beta
  • IKK2
  • IKKB
  • EG3551
    		•  The BioGRID Database Seperator inhibitor of nuclear factor kappa B kinase beta subunit|nuclear factor NF-kappa-B inhibitor kinase beta; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
    Gene Ontology: [View List]
    Invivo
    bait Chaudhary PM (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RIPK2
  • CARD3
  • CARDIAK
  • RICK
  • WUGSC:H_R...
    		•  The BioGRID Database Seperator CARD-carrying kinase|CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase|growth-inhibiting gene 30|receptor interacting protein 2|receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; receptor-intera...
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Inohara N (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SF3B3
  • KIAA0017
  • RSE1
  • SAP130
  • EG23450
    		•  The BioGRID Database Seperator pre-mRNA splicing factor SF3b, 130 kDa subunit|spliceosome-associated protein 130|splicing factor 3b, subunit 3; splicing factor 3b, subunit 3, 130kDa
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCL2L1
  • BCL-XL/S
  • BCL2L
  • BCLX
  • EG598
    		•  The BioGRID Database Seperator BCL2-like 1
    Gene Ontology: [View List]
    Invivo
    bait Han DK (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CASP3
  • CPP32
  • CPP32B
  • SCA-1
  • EG836
    		•  The BioGRID Database Seperator PARP cleavage protease|SREBP cleavage activity 1|Yama|apopain|caspase 3|caspase 3, apoptosis-related cysteine protease|cysteine protease CPP32|procaspase3; caspase 3, apoptosis-related cysteine peptidase
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Shu HB (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DEDD
  • CASP8IP1
  • DEDD1
  • DEFT
  • EG9191
    		•  The BioGRID Database Seperator death effector domain-containing|death effector domain-containing protein; death effector domain containing
    Gene Ontology: [View List]
    Invitro
    bait Roth W (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DOK2
  • p56DOK
  • p56dok-2
  • EG9046
    		•  The BioGRID Database Seperator docking protein 2, 56kDa; docking protein 2
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    terms and conditions - privacy policy - Osprey Network Visualization System
    BioGRID: A General Repository for Interaction Datasets.
    Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
    Nucleic Acids Res. Jan 1;34:D535-9.