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BioGRID | Network Layout for FADD for Homo sapiens
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FADD

 Homo sapiens
The BioGRID Database Seperator
Aliases: GIG3, MGC8528, MORT1, EG8772
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Fas-associated via death domain|Fas-associating death domain-containing protein|Fas-associating protein with death domain|growth-inhibiting gene 3 protein|mediator of receptor-induced toxicity; Fas (TNFRSF6)-associated via death domain
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 10 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with FADD

FADD was identified with 89 protein interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 FAS
  • ALPS1A
  • APO-1
  • APT1
  • EG355
    		•  The BioGRID Database Seperator APO-1 cell surface antigen|CD95 antigen|Fas antigen|OTTHUMP00000059646|apoptosis antigen 1|tumor necrosis factor receptor superfamily, member 6; Fas (TNF receptor superfamily, member 6)
    Gene Ontology: [View List]
    Invivo
    hit Huang B ()
    hit Chinnaiyan AM (1995)
    Invitro
    hit Huang B ()
    hit Chinnaiyan AM (1995)
    Two-hybrid
    hit Huang B ()
    hit Chinnaiyan AM (1995)
    Affinity Capture-MS
    bait Rual JF (2005)
    Co-purification
    bait Gajate C (2005)
    Affinity Capture-Western
    hit MacFarlane M (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CFLAR
  • CASH
  • CASP8AP1
  • CLARP
  • EG8837
    		•  The BioGRID Database Seperator FADD-like anti-apoptotic molecule; Inhibitor of FLICE; Caspase-related inducer of apoptosis; Caspase homolog; Caspase-like apoptosis regulatory protein|usurpin beta; CASP8 and FADD-like apoptosis regulator
    Gene Ontology: [View List]
    Invivo
    bait Zhan Y (2002)
    Invitro
    bait Zhan Y (2002)
    Two-hybrid
    bait Zhan Y (2002)
    bait/hit Srinivasula SM (1997)
    Affinity Capture-MS
    hit Rual JF (2005)
    Affinity Capture-Western
    bait Shu HB (1997)
    bait/hit Srinivasula SM (1997)
    Reconstituted Complex
    bait/hit Srinivasula SM (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNFRSF10A
  • APO2
  • DR4
  • MGC9365
  • EG8797
    		•  The BioGRID Database Seperator TNF-related apoptosis inducing ligand receptor 1|cytotoxic TRAIL receptor|death receptor 4; tumor necrosis factor receptor superfamily, member 10a
    Gene Ontology: [View List]
    Invivo
    bait Miyazaki T (2001)
    bait Chaudhary PM (1997)
    Invitro
    bait Miyazaki T (2001)
    bait Chaudhary PM (1997)
    Two-hybrid
    bait Miyazaki T (2001)
    bait Chaudhary PM (1997)
    Affinity Capture-MS
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CASP10
  • ALPS2
  • FLICE2
  • MCH4
  • EG843
    		•  The BioGRID Database Seperator FADD-like ICE2|Fas-associated death domain protein|ICE-like apoptotic protease 4|apoptotic protease MCH-4|caspase 10|caspase 10, apoptosis-related cysteine protease|interleukin-1B-converting enzyme 2; caspase 10, apoptosis-related cysteine peptidase
    Gene Ontology: [View List]
    Invivo
    bait Wang J (2001)
    Co-purification
    bait Gajate C (2005)
    Affinity Capture-Western
    hit Vincenz C (1997)
    bait Srinivasula SM (1997)
    Reconstituted Complex
    hit Vincenz C (1997)
    hit Srinivasula SM (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PEA15
  • HMAT1
  • HUMMAT1H
  • MAT1
  • RP11-536C...
    		•  The BioGRID Database Seperator Phosphoprotein enriched in astrocytes, 15kD|homolog of mouse MAT-1 oncogene; phosphoprotein enriched in astrocytes 15
    Gene Ontology: [View List]
    Invivo
    hit Kitsberg D (1999)
    hit Condorelli G (1999)
    Invitro
    hit Kitsberg D (1999)
    hit Condorelli G (1999)
    Affinity Capture-MS
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CASP8
  • FLICE
  • MACH
  • MCH5
  • EG841
    		•  The BioGRID Database Seperator FADD-homologous ICE/CED-3-like protease|MACH-alpha-1/2/3 protein|MACH-beta-1/2/3/4 protein|Mch5 isoform alpha|caspase 8|caspase 8, apoptosis-related cysteine protease|cysteine protease|procaspase-8; caspase 8, apoptosis-related cysteine peptidase
    Gene Ontology: [View List]
    Two-hybrid
    bait Thomas LR (2002)
    Co-purification
    bait Gajate C (2005)
    Affinity Capture-Western
    bait Micheau O (2003)
    bait Srinivasula SM (1997)
    Reconstituted Complex
    hit Srinivasula SM (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRADD
  • Hs.89862
  • MGC11078
  • EG8717
    		•  The BioGRID Database Seperator TNFR1-associated death domain protein|tumor necrosis factor receptor type 1 associated death domain protein|tumor necrosis factor receptor-1-associated protein; TNFRSF1A-associated via death domain
    Gene Ontology: [View List]
    Invivo
    hit Hsu H (1996)
    hit Tsao DH (2000)
    Two-hybrid
    hit Hsu H (1996)
    hit Tsao DH (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DAP3
  • DAP-3
  • DKFZp686G...
  • MRP-S29
  • EG7818
    		•  The BioGRID Database Seperator death-associated protein 3|mitochondrial 28S ribosomal protein S29; death associated protein 3
    Gene Ontology: [View List]
    Invivo
    hit Berger T (2002)
    hit Miyazaki T (2001)
    Two-hybrid
    hit Berger T (2002)
    hit Miyazaki T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNFRSF10B
  • DR5
  • KILLER
  • KILLER/DR5
  • EG8795
    		•  The BioGRID Database Seperator Fas-like protein|TNF-related apoptosis-inducing ligand receptor 2|TRAIL receptor 2|apoptosis inducing protein TRICK2A/2B|apoptosis inducing receptor TRAIL-R2|cytotoxic TRAIL receptor-2|death domain containing receptor for TRAIL/Apo-2L|death receptor 5|p53-regulated DNA damage-inducible cell...
    Gene Ontology: [View List]
    Invivo
    bait Chaudhary PM (1997)
    Affinity Capture-MS
    hit Rual JF (2005)
    Co-purification
    hit Gajate C (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MYD88
  • EG4615
    		•  The BioGRID Database Seperator myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88
    Gene Ontology: [View List]
    Invivo
    bait Bannerman DD (2002)
    Invitro
    bait Bannerman DD (2002)
    Affinity Capture-MS
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MBD4
  • MED1
  • EG8930
    		•  The BioGRID Database Seperator 3,N(4)-ethenocytosine glycosylase|G/5-fluorouracil mismatch glycosylase with biphasic kinetics|G/T mismatch glycosylase|G/U mismatch glycosylase|putative methyl-CpG binding protein; methyl-CpG binding domain protein 4
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rual JF (2005)
    Affinity Capture-Western
    bait/hit Screaton RA (2003)
    Two-hybrid
    hit Screaton RA (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DEDD
  • CASP8IP1
  • DEDD1
  • DEFT
  • EG9191
    		•  The BioGRID Database Seperator death effector domain-containing|death effector domain-containing protein; death effector domain containing
    Gene Ontology: [View List]
    Invivo
    bait Stegh AH (1998)
    Invitro
    bait Stegh AH (1998)
    Affinity Capture-MS
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RIPK1
  • FLJ39204
  • RIP
  • RIP1
  • EG8737
    		•  The BioGRID Database Seperator receptor (TNFRSF)-interacting serine-threonine kinase 1; OTTHUMP00000039163|receptor interacting protein
    Gene Ontology: [View List]
    Invivo
    hit Kim JW (2000)
    Two-hybrid
    bait Chen D (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FASLG
  • APT1LG1
  • CD178
  • CD95L
  • EG356
    		•  The BioGRID Database Seperator CD95 ligand|apoptosis (APO-1) antigen ligand 1|fas ligand|tumor necrosis factor (ligand) superfamily, member 6; Fas ligand (TNF superfamily, member 6)
    Gene Ontology: [View List]
    Co-purification
    hit Gajate C (2005)
    Affinity Capture-Western
    bait Micheau O (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RYBP
  • AAP1
  • DEDAF
  • YEAF1
  • EG23429
    		•  The BioGRID Database Seperator YY1 and E4TF1 associated factor 1|apoptin-associating protein 1|death effector domain-associated factor|ring1 interactor RYBP; RING1 and YY1 binding protein
    Gene Ontology: [View List]
    Invivo
    bait Zheng L (2001)
    Affinity Capture-MS
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NACA
  • MGC117224
  • HSD48
  • NACA1
  • EG4666
    		•  The BioGRID Database Seperator nascent-polypeptide-associated complex alpha polypeptide; nascent polypeptide-associated complex alpha subunit
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Stilo R (2003)
    Reconstituted Complex
    bait Stilo R (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LRDD
  • DKFZp434D...
  • MGC16925
  • PIDD
  • EG55367
    		•  The BioGRID Database Seperator leucine rich repeat and death domain containing protein|leucine-rich and death domain containing; leucine-rich repeats and death domain containing
    Gene Ontology: [View List]
    Invivo
    hit Telliez JB (2000)
    Affinity Capture-MS
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKCZ
  • PKC2
  • EG5590
    		•  The BioGRID Database Seperator protein kinase C, zeta; OTTHUMP00000044160
    Gene Ontology: [View List]
    Invivo
    bait de Thonel A (2001)
    Affinity Capture-MS
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DAPK1
  • DAPK
  • DKFZp781I...
  • EG1612
    		•  The BioGRID Database Seperator death-associated protein kinase 1
    Gene Ontology: [View List]
    Invitro
    bait Henshall DC (2003)
    Invivo
    bait Henshall DC (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ABCA1
  • ABC-1
  • ABC1
  • CERP
  • EG19
    		•  The BioGRID Database Seperator ATP binding cassette transporter 1|ATP-binding cassette 1|ATP-binding cassette transporter-1|ATP-binding cassette, sub-family A member 1|cholesterol efflux regulatory protein|high density lipoprotein deficiency, Tangier type, 1|membrane-bound; ATP-binding cassette, sub-family A (ABC1), member 1
    Gene Ontology: [View List]
    Two-hybrid
    bait Buechler C (2002)
    Reconstituted Complex
    bait/hit Buechler C (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IRAK1
  • IRAK
  • pelle
  • EG3654
    		•  The BioGRID Database Seperator interleukin-1 receptor-associated kinase 1; Pelle (Drosophila) homolog
    Gene Ontology: [View List]
    Invitro
    bait Bannerman DD (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MSN
  • EG4478
    		•  The BioGRID Database Seperator moesin
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNFRSF1A
  • CD120a
  • FPF
  • MGC19588
  • EG7132
    		•  The BioGRID Database Seperator tumor necrosis factor binding protein 1|tumor necrosis factor receptor 1|tumor necrosis factor receptor type 1|tumor necrosis factor-alpha receptor; tumor necrosis factor receptor superfamily, member 1A
    Gene Ontology: [View List]
    Co-purification
    hit Gajate C (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SUMO1
  • GMP1
  • PIC1
  • SENP2
  • EG7341
    		•  The BioGRID Database Seperator GAP modifying protein 1|SMT3 suppressor of mif two 3 homolog 1|sentrin|ubiquitin-like 1 (sentrin); SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
    Gene Ontology: [View List]
    Two-hybrid
    bait Okura T (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK8
  • JNK
  • JNK1
  • JNK1A2
  • EG5599
    		•  The BioGRID Database Seperator JNK1 alpha protein kinase|JNK1 beta protein kinase|c-Jun N-terminal kinase 1|protein kinase JNK1|stress-activated protein kinase JNK1; mitogen-activated protein kinase 8
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PREI3
  • 2C4D
  • CGI-95
  • MGC12264
  • EG25843
    		•  The BioGRID Database Seperator Mps One Binder kinase activator-like 3|phocein|preimplantation protein 3; MOB1, Mps One Binder kinase activator-like 3 (yeast)
    Gene Ontology: [View List]
    Two-hybrid
    bait Stelzl U (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BID
  • MGC15319
  • MGC42355
  • FP497
  • EG637
    		•  The BioGRID Database Seperator BH3-interacting domain death agonist|Human BID coding sequence|apoptic death agonist|desmocollin type 4; BH3 interacting domain death agonist
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     XPO5
  • KIAA1291
  • FLJ14239
  • FLJ32057
  • RP3-337H4.5
    		•  The BioGRID Database Seperator exportin 5
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HIPK3
  • DYRK6
  • PKY
  • YAK1
  • RP1-8L15.1
    		•  The BioGRID Database Seperator homeodomain interacting protein kinase 3; homeodomain-interacting protein kinase 3
    Gene Ontology: [View List]
    Invivo
    bait Rochat-Steiner V (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RHOA
  • ARH12
  • ARHA
  • RHO12
  • EG387
    		•  The BioGRID Database Seperator Aplysia ras-related homolog 12|oncogene RHO H12|small GTP binding protein RhoA; ras homolog gene family, member A
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARHGDIA
  • GDIA1
  • RHOGDI
  • MGC117248
  • EG396
    		•  The BioGRID Database Seperator Rho GDP dissociation inhibitor (GDI) alpha
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CASP8AP2
  • CED-4
  • FLASH
  • FLJ11208
  • EG9994
    		•  The BioGRID Database Seperator FLASH homolog RIP25|FLICE associated huge|human FLASH; CASP8 associated protein 2
    Gene Ontology: [View List]
    Invivo
    bait/hit Imai Y (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VIL2
  • CVIL
  • CVL
  • DKFZp762H...
  • EG7430
    		•  The BioGRID Database Seperator cytovillin 2|villin 2 (ezrin); ezrin
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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