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BioGRID | Network Layout for FADD for Homo sapiens
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FADD

 Homo sapiens
The BioGRID Database Seperator
Aliases: MGC8528, MORT1, GIG3
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Fas-associating death domain-containing protein
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [UniprotKB] | [UniprotKB] | [OMIM] | [HPRD] | [Entrez Gene]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 8 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with FADD

FADD was identified with 67 protein interactions and 1 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code
Role Source [Interactions]
The BioGRID Database Seperator
 FAS
  • TNFRSF6
  • CD95
  • APO-1
    		•  The BioGRID Database Seperator tumor necrosis factor receptor superfamily, member 6
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005) [78]
    Affinity Capture-Western
    hit MacFarlane M (1997) [10]
    hit Pan G (1997) [3]
    hit Chinnaiyan AM (1995) [3]
    Co-crystal Structure
    hit Huang B () [2]
    Reconstituted Complex
    hit Huang B () [2]
    hit Chinnaiyan AM (1995) [3]
    Two-hybrid
    hit Chinnaiyan AM (1995) [3]
    hit Thomas LR (2002) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CASP8
  • MACH
  • FLICE
  • FLJ17672
    		•  The BioGRID Database Seperator caspase 8, apoptosis-related cysteine peptidase
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005) [78]
    Affinity Capture-Western
    bait Micheau O (2003) [17]
    bait Srinivasula SM (1997) [16]
    hit Henshall DC (2003) [6]
    bait Oshima S (2009) [3]
    Reconstituted Complex
    hit Srinivasula SM (1997) [16]
    Two-hybrid
    bait Boldin MP (1996) [1]
    hit Thomas LR (2002) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CASP10
  • ALPS2
  • MCH4
  • FLICE2
    		•  The BioGRID Database Seperator caspase 10, apoptosis-related cysteine peptidase
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005) [78]
    Affinity Capture-Western
    hit Vincenz C (1997) [4]
    bait Srinivasula SM (1997) [16]
    Reconstituted Complex
    hit Vincenz C (1997) [4]
    hit Srinivasula SM (1997) [16]
    FRET
    bait Wang J (2001) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CFLAR
  • FLAME-1
  • c-FLIPR
  • FLIP
    		•  The BioGRID Database Seperator CASP8 and FADD-like apoptosis regulator
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Shu HB (1997) [7]
    bait/hit Srinivasula SM (1997) [16]
    Reconstituted Complex
    bait/hit Srinivasula SM (1997) [16]
    Two-hybrid
    bait Srinivasula SM (1997) [16]
    bait Han DK (1997) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRADD
  • MGC11078
  • Hs.89862
    		•  The BioGRID Database Seperator tumor necrosis factor receptor type 1 associated death domain protein
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Henshall DC (2003) [6]
    hit Hsu H (1996) [10]
    Two-hybrid
    bait Hsu H (1996) [10]
    hit Thomas LR (2002) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DEDD
  • DEDD1
  • FLDED1
  • DEFT
    		•  The BioGRID Database Seperator death effector domain-containing protein
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Roth W (2002) [5]
    hit Stegh AH (1998) [4]
    Reconstituted Complex
    hit Stegh AH (1998) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MBD4
  • MED1
    		•  The BioGRID Database Seperator G/5-fluorouracil mismatch glycosylase with biphasic kinetics
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Screaton RA (2003) [3]
    Two-hybrid
    hit Screaton RA (2003) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNFRSF1A
  • FPF
  • TNFR1
  • TNF-R-I
    		•  The BioGRID Database Seperator tumor necrosis factor receptor superfamily, member 1A
    Gene Ontology: [View List]
    Co-purification
    hit Gajate C (2005) [78]
    Affinity Capture-Western
    bait Hsu H (1996) [10]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ABCA1
  • FLJ14958
  • HDLDT1
  • ABC1
    		•  The BioGRID Database Seperator ATP-binding cassette, sub-family A (ABC1), member 1
    Gene Ontology: [View List]
    Two-hybrid
    bait Buechler C (2002) [3]
    Reconstituted Complex
    bait/hit Buechler C (2002) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DAP3
  • MRP-S29
  • MGC126058
  • MRPS29
    		•  The BioGRID Database Seperator mitochondrial 28S ribosomal protein S29
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Miyazaki T (2001) [5]
    Two-hybrid
    hit Miyazaki T (2001) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NACA
  • HSD48
  • NACA1
  • MGC117224
    		•  The BioGRID Database Seperator nascent-polypeptide-associated complex alpha polypeptide
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Stilo R (2003) [3]
    Reconstituted Complex
    bait Stilo R (2003) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FASLG
  • APT1LG1
  • CD178
  • CD95L
    		•  The BioGRID Database Seperator tumor necrosis factor (ligand) superfamily, member 6
    Gene Ontology: [View List]
    Co-purification
    hit Gajate C (2005) [78]
    Affinity Capture-Western
    bait Micheau O (2003) [17]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNFRSF10B
  • DR5
  • TRICK2B
  • TRAILR2
    		•  The BioGRID Database Seperator p53-regulated DNA damage-inducible cell death receptor(killer)
    Gene Ontology: [View List]
    Co-purification
    hit Gajate C (2005) [78]
    Affinity Capture-Western
    bait Chaudhary PM (1997) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PEA15
  • PEA-15
  • MAT1
  • HUMMAT1H
  • RP11-536C...
    		•  The BioGRID Database Seperator Phosphoprotein enriched in astrocytes, 15kD
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Kitsberg D (1999) [2]
    Affinity Capture-Western
    hit Condorelli G (1999) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKCZ
  • PKC-ZETA
  • PKC2
    		•  The BioGRID Database Seperator protein kinase C, zeta
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit de Thonel A (2001) [1]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DAPK1
  • DAPK
  • DKFZp781I...
    		•  The BioGRID Database Seperator death-associated protein kinase 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Henshall DC (2003) [6]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TNFRSF10A
  • TRAILR-1
  • DR4
  • APO2
    		•  The BioGRID Database Seperator tumor necrosis factor receptor superfamily, member 10a
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Chaudhary PM (1997) [5]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CASP8AP2
  • FLASH
  • KIAA1315
  • RIP25
    		•  The BioGRID Database Seperator caspase 8 associated protein 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Imai Y (1999) [4]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HIPK3
  • PKY
  • YAK1
  • DYRK6
  • RP1-8L15.1
    		•  The BioGRID Database Seperator homeodomain interacting protein kinase 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Rochat-Steiner V (2000) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LRDD
  • DKFZp434D...
  • MGC16925
  • PIDD
    		•  The BioGRID Database Seperator leucine rich repeat and death domain containing protein
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Telliez JB (2000) [2]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MOBKL3
  • CGI-95
  • MGC12264
  • MOB3
    		•  The BioGRID Database Seperator MOB1, Mps One Binder kinase activator-like 3 (yeast)
    Gene Ontology: [View List]
    Two-hybrid
    bait Stelzl U (2005) [2527]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BID
  • FP497
  • MGC42355
  • MGC15319
    		•  The BioGRID Database Seperator BH3 interacting domain death agonist
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005) [78]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARHGDIA
  • MGC117248
  • RHOGDI
  • GDIA1
    		•  The BioGRID Database Seperator Rho GDP dissociation inhibitor (GDI) alpha
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005) [78]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RHOA
  • RHOH12
  • ARHA
  • RHO12
    		•  The BioGRID Database Seperator ras homolog gene family, member A
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005) [78]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EZR
  • VIL2
  • DKFZp762H...
  • CVIL
    		•  The BioGRID Database Seperator villin 2 (ezrin)
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005) [78]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK8
  • PRKM8
  • SAPK1
  • JNK21B1/2
    		•  The BioGRID Database Seperator mitogen-activated protein kinase 8 isoform JNK1 alpha1
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005) [78]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SUMO1
  • PIC1
  • SENP2
  • DAP-1
    		•  The BioGRID Database Seperator SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
    Gene Ontology: [View List]
    Two-hybrid
    bait Okura T (1996) [7]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RYBP
  • DEDAF
  • YEAF1
  • AAP1
    		•  The BioGRID Database Seperator death effector domain-associated factor
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Zheng L (2001) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RIPK1
  • RIP
  • RIP1
  • FLJ39204
    		•  The BioGRID Database Seperator receptor (TNFRSF)-interacting serine-threonine kinase 1
    Gene Ontology: [View List]
    Two-hybrid
    bait Chen D (2002) [3]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MSN
  • N/A
    		•  The BioGRID Database Seperator moesin
    Gene Ontology: [View List]
    Co-purification
    bait Gajate C (2005) [78]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NOL3
  • MYC
  • NOP30
  • CARD2
    		•  The BioGRID Database Seperator nucleolar protein 3 (apoptosis repressor with CARD domain)
    Gene Ontology: [View List]
    Phenotypic Suppression
    hit Koseki T (1998) [11]
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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