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BioGRID | Network Layout for IRS2 for Homo sapiens
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IRS2

 Homo sapiens
The BioGRID Database Seperator
Aliases: EG8660
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: insulin receptor substrate 2
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 4 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with IRS2

IRS2 was identified with 25 protein interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 PIK3R1
  • GRB1
  • p85-ALPHA
  • EG5295
    		•  The BioGRID Database Seperator phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)|phosphatidylinositol 3-kinase, regulatory, 1|phosphatidylinositol 3-kinase-associated p-85 alpha|phosphoinositide-3-kinase, regulatory subunit, polypeptide 1|phosphoinositide-3-kinase, regulatory subunit, polypeptide...
    Gene Ontology: [View List]
    Invivo
    hit Hamer I (2002)
    Affinity Capture-Western
    hit Argetsinger LS (1996)
    hit Verdier F (1997)
    hit Kim B (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TYK2
  • JTK1
  • EG7297
    		•  The BioGRID Database Seperator tyrosine kinase 2
    Gene Ontology: [View List]
    Invivo
    hit Platanias LC (1996)
    Invitro
    hit Platanias LC (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PIK3R3
  • DKFZp686P...
  • p55-GAMMA
  • FLJ41892
  • EG8503
    		•  The BioGRID Database Seperator 100% homology to SWISS-PROT Q92569|phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)|phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma); phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Xia X (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN11
  • BPTP3
  • CFC
  • MGC14433
  • EG5781
    		•  The BioGRID Database Seperator protein tyrosine phosphatase, non-receptor type 11|protein-tyrosine phosphatase 2C; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Argetsinger LS (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     INSR
  • CD220
  • HHF5
  • EG3643
    		•  The BioGRID Database Seperator insulin receptor
    Gene Ontology: [View List]
    Two-hybrid
    bait Sawka-Verhelle D (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SOCS1
  • CIS1
  • CISH1
  • JAB
  • EG8651
    		•  The BioGRID Database Seperator JAK binding protein|STAT induced SH3 protein 1|Tec-interacting protein 3|cytokine-inducible SH2 protein 1; suppressor of cytokine signaling 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Rui L (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCL2
  • Bcl-2
  • EG596
    		•  The BioGRID Database Seperator B-cell lymphoma protein 2; B-cell CLL/lymphoma 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Ueno H (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NISCH
  • I-1
  • IRAS
  • KIAA0975
  • EG11188
    		•  The BioGRID Database Seperator I-1 receptor candidate protein|imidazoline receptor antisera selected|imidazoline receptor candidate; nischarin
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Sano H (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JAK1
  • JAK1A
  • JAK1B
  • EG3716
    		•  The BioGRID Database Seperator Janus kinase 1 (a protein tyrosine kinase); janus kinase 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Johnston JA (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SFN
  • YWHAS
  • EG2810
    		•  The BioGRID Database Seperator 14-3-3 sigma; stratifin
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Benzinger A (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EPOR
  • MGC138358
  • EG2057
    		•  The BioGRID Database Seperator erythropoietin receptor
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Verdier F (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAG
  • 14-3-3GAMMA
  • EG7532
    		•  The BioGRID Database Seperator tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 14-3-3 gamma
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SHC1
  • FLJ26504
  • SHC
  • SHCA
  • EG6464
    		•  The BioGRID Database Seperator SHC (Src homology 2 domain containing) transforming protein 1; SHC (Src homology 2 domain-containing) transforming protein 1
    Gene Ontology: [View List]
    Invitro
    hit Hallak H (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLCG1
  • PLC-II
  • PLC1
  • PLC148
  • EG5335
    		•  The BioGRID Database Seperator 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1|PLC-gamma-1|inositoltrisphosphohydrolase|monophosphatidylinositol phosphodiesterase|phosphatidylinositol phospholipase C|phosphoinositidase C|phosphoinositide phosphol...
    Gene Ontology: [View List]
    Invivo
    bait Sozzani P (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IL4R
  • CD124
  • IL4RA
  • EG3566
    		•  The BioGRID Database Seperator interleukin 4 receptor alpha chain|interleukin-4 receptor alpha chain; interleukin 4 receptor
    Gene Ontology: [View List]
    Invitro
    bait Izuhara K (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     UBTF
  • NOR-90
  • UBF
  • EG7343
    		•  The BioGRID Database Seperator upstream binding transcription factor, RNA polymerase I
    Gene Ontology: [View List]
    Invivo
    bait Sun H (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAZ
  • KCIP-1
  • MGC111427
  • MGC126532
  • EG7534
    		•  The BioGRID Database Seperator 14-3-3 protein/cytosolic phospholipase A2|14-3-3 zeta|phospholipase A2|protein kinase C inhibitor protein-1|tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
    Gene Ontology: [View List]
    Invivo
    bait Ogihara T (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB2
  • ASH
  • EGFRBP-GRB2
  • Grb3-3
  • EG2885
    		•  The BioGRID Database Seperator HT027|abundant SRC homology|epidermal growth factor receptor-binding protein GRB2|growth factor receptor-bound protein 3; growth factor receptor-bound protein 2
    Gene Ontology: [View List]
    Invivo
    hit Patti ME (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAB
  • GW128
  • HS1
  • KCIP-1
  • EG7529
    		•  The BioGRID Database Seperator 14-3-3 protein beta/alpha|brain protein 14-3-3, beta isoform|protein 1054|protein kinase C inhibitor protein-1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAE
  • 14-3-3E
  • KCIP-1
  • MDCR
  • EG7531
    		•  The BioGRID Database Seperator 14-3-3 epsilon|mitochondrial import stimulation factor L subunit|protein kinase C inhibitor protein-1|tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
    Gene Ontology: [View List]
    Invivo
    bait Ogihara T (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAQ
  • 1C5
  • HS1
  • 14-3-3
  • EG10971
    		•  The BioGRID Database Seperator 14-3-3 protein T-cell|14-3-3 protein tau|14-3-3 protein theta|protein tau|tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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