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BioGRID | Network Layout for WRN for Homo sapiens
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WRN

 Homo sapiens
The BioGRID Database Seperator
Aliases: RECQ3, RECQL2, RECQL3, DKFZp686C2056, EG7486
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Werner Syndrome helicase|Werner syndrome protein; Werner syndrome
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 9 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with WRN

WRN was identified with 32 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 TERF2
  • TRBF2
  • TRF2
  • EG7014
    		•  The BioGRID Database Seperator telomeric repeat binding protein 2; telomeric repeat binding factor 2
    Gene Ontology: [View List]
    Invivo
    hit Opresko PL (2002)
    Invitro
    hit Opresko PL (2002)
    Affinity Capture-Western
    bait/hit Opresko PL (2002)
    Reconstituted Complex
    bait/hit Opresko PL (2002)
    Co-localization
    hit Opresko PL (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FEN1
  • FEN-1
  • MF1
  • RAD2
  • EG2237
    		•  The BioGRID Database Seperator flap structure-specific endonuclease 1; DNase IV|maturation factor-1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Sharma S (2004)
    bait Brosh RM (2001)
    Affinity Capture-Western
    bait Brosh RM (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     WRNIP1
  • FLJ22526
  • WHIP
  • bA420G6.2
  • EG56897
    		•  The BioGRID Database Seperator Werner helicase interacting protein|putative helicase RUVBL; Werner helicase interacting protein 1
    Gene Ontology: [View List]
    Two-hybrid
    hit Kawabe Yi (2001)
    Affinity Capture-Western
    bait/hit Kawabe Yi (2001)
    Reconstituted Complex
    bait Kawabe Yi (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     XRCC6
  • CTC75
  • CTCBF
  • G22P1
  • EG2547
    		•  The BioGRID Database Seperator ATP-dependent DNA helicase II, 70 kDa subunit|CTC box binding factor 75 kDa subunit|Ku autoantigen p70 subunit|OTTHUMP00000028581|thyroid autoantigen 70kD (Ku antigen)|thyroid autoantigen 70kDa (Ku antigen)|thyroid-lupus autoantigen p70; X-ray repair complementing defective repair in Chinese...
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Karmakar P (2002)
    hit Li B (2000)
    Reconstituted Complex
    hit Karmakar P (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TP53
  • TRP53
  • p53
  • LFS1
  • EG7157
    		•  The BioGRID Database Seperator tumor protein p53 (Li-Fraumeni syndrome); p53 tumor suppressor|tumor protein p53
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Yang Q (2002)
    Reconstituted Complex
    hit Yang Q (2002)
    bait Brosh RM (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     XRCC5
  • KARP-1
  • KARP1
  • KU80
  • EG7520
    		•  The BioGRID Database Seperator ATP-dependent DNA helicase II|DNA repair protein XRCC5|Ku86 autoantigen related protein 1|X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kD)|X-ray repair, complementing defective, repair in Chinese hamster; X-ray repair...
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Karmakar P (2002)
    hit Li B (2000)
    Reconstituted Complex
    hit Karmakar P (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKDC
  • DNAPK
  • DNPK1
  • HYRC
  • EG5591
    		•  The BioGRID Database Seperator hyper-radiosensitivity of murine scid mutation, complementing 1; protein kinase, DNA-activated, catalytic polypeptide
    Gene Ontology: [View List]
    Protein-peptide
    bait Kim ST (1999)
    Affinity Capture-Western
    hit Karmakar P (2002)
    Biochemical Activity
    bait Karmakar P (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BLM
  • BS
  • RECQ2
  • RECQL2
  • EG641
    		•  The BioGRID Database Seperator Bloom syndrome protein; Bloom syndrome
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait von Kobbe C (2002)
    Reconstituted Complex
    bait von Kobbe C (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PCNA
  • MGC8367
  • EG5111
    		•  The BioGRID Database Seperator DNA polymerase delta auxiliary protein|cyclin; proliferating cell nuclear antigen
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Rodriguez-Lopez AM (2003)
    Reconstituted Complex
    bait Huang S (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MDC1
  • KIAA0170
  • NFBD1
  • DKFZp781A...
  • DAQB-47P1...
    		•  The BioGRID Database Seperator homologue to Drosophila photoreceptor protein calphotin|nuclear factor with BRCT domains 1; mediator of DNA damage checkpoint 1
    Gene Ontology: [View List]
    Protein-peptide
    bait Rodriguez M (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GIS1
  • YDR096W
    		•  The BioGRID Database Seperator Gis1p|JmjC domain-containing histone demethylase; transcription factor involved in the expression of genes during nutrient limitation; also involved in the negative regulation of DPP1 and PHR1; protein coding
    Gene Ontology: [View List]
    Two-hybrid
    bait Tronnersjo S (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     POLR1C
  • RPA39
  • RPA40
  • RPA5
  • EG9533
    		•  The BioGRID Database Seperator polymerase (RNA) I polypeptide C, 30kDa; RNA polymerase I subunit
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Shiratori M (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ATM
  • AT1
  • ATA
  • ATC
  • EG472
    		•  The BioGRID Database Seperator AT complementation group A|AT complementation group C|AT complementation group D|AT complementation group E|AT mutated|AT protein|TEL1, telomere maintenance 1, homolog|ataxia telangiectasia mutated (includes complementation groups A, C and D)|ataxia telangiectasia mutated protein...
    Gene Ontology: [View List]
    Protein-peptide
    bait/hit Kim ST (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ATR
  • FRP1
  • SCKL
  • SCKL1
  • EG545
    		•  The BioGRID Database Seperator FRAP-related protein-1|MEC1, mitosis entry checkpoint 1, homolog|Rad3 related protein|Seckel syndrome|ataxia telangiectasia and Rad3 related protein|protein kinase ATR; ataxia telangiectasia and Rad3 related
    Gene Ontology: [View List]
    Protein-peptide
    bait/hit Kim ST (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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