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BioGRID | Network Layout for VHL for Homo sapiens
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VHL

 Homo sapiens
The BioGRID Database Seperator
Aliases: HRCA1, RCA1, VHL1, EG7428
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: von Hippel-Lindau tumor suppressor; elongin binding protein
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 14 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with VHL

VHL was identified with 85 protein interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 HIF1A
  • HIF-1alpha
  • HIF1-ALPHA
  • MOP1
  • EG3091
    		•  The BioGRID Database Seperator ARNT interacting protein|hypoxia-inducible factor 1, alpha subunit|member of PAS superfamily 1; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Corn PG (2003)
    bait Li Z (2003)
    hit Yu F (2001)
    Reconstituted Complex
    bait Mahon PC (2001)
    hit Tanimoto K (2000)
    bait Yu F (2001)
    Co-crystal Structure
    hit Min JH (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TCEB1
  • SIII
  • EG6921
    		•  The BioGRID Database Seperator elongin C|transcription elongation factor B (SIII), polypeptide 1 (15kD, elongin C)|transcription elongation factor B, polypeptide 1; transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    Reconstituted Complex
    hit Ohh M (1999)
    bait Li Z (2002)
    Two-hybrid
    hit Tsuchiya H (1996)
    Co-crystal Structure
    hit Min JH (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TCEB2
  • SIII
  • EG6923
    		•  The BioGRID Database Seperator elongin B|transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B)|transcription elongation factor B, polypeptide 2; transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    Reconstituted Complex
    hit Ohh M (1999)
    Affinity Capture-Western
    hit Ohh M (1999)
    Co-crystal Structure
    hit Min JH (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CUL2
  • MGC131970
  • EG8453
    		•  The BioGRID Database Seperator OTTHUMP00000046331; cullin 2
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    Affinity Capture-Western
    hit Ohh M (1999)
    Reconstituted Complex
    bait Kamura T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VBP1
  • PFD3
  • PFDN3
  • VBP-1
  • RP13-228J...
    		•  The BioGRID Database Seperator von Hippel-Lindau binding protein 1; VHL binding protein-1|prefoldin 3
    Gene Ontology: [View List]
    Two-hybrid
    hit Tsuchiya H (1996)
    hit Zhou MI (2002)
    Affinity Capture-Western
    hit Tsuchiya H (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ZNF197
  • D3S1363E
  • P18
  • VHLaK
  • EG10168
    		•  The BioGRID Database Seperator VHL-associated KRAB-A domain-containing protein|zinc finger protein 166|zinc finger protein 20; zinc finger protein 197
    Gene Ontology: [View List]
    Two-hybrid
    hit Li Z (2003)
    Reconstituted Complex
    hit Li Z (2003)
    Affinity Capture-Western
    hit Li Z (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     USP33
  • KIAA1097
  • MGC16868
  • VDU1
  • EG23032
    		•  The BioGRID Database Seperator pVHL-interacting deubiquitinating enzyme 1|ubiquitin specific protease 33; ubiquitin specific peptidase 33
    Gene Ontology: [View List]
    Two-hybrid
    hit Li Z (2002)
    Reconstituted Complex
    hit Li Z (2002)
    Affinity Capture-Western
    hit Li Z (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PSMC3
  • MGC8487
  • TBP1
  • EG5702
    		•  The BioGRID Database Seperator Tat-binding protein 1|human immunodeficiency virus tat transactivator binding protein-1|proteasome 26S ATPase subunit 3|proteasome subunit P50; proteasome (prosome, macropain) 26S subunit, ATPase, 3
    Gene Ontology: [View List]
    Two-hybrid
    hit Corn PG (2003)
    Affinity Capture-Western
    bait/hit Corn PG (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PHF17
  • FLJ22479
  • JADE1
  • KIAA1807
  • EG79960
    		•  The BioGRID Database Seperator PHD protein Jade-1|gene for apoptosis and differentiation in epithelia; PHD finger protein 17
    Gene Ontology: [View List]
    Two-hybrid
    hit Zhou MI (2002)
    Affinity Capture-Western
    bait Zhou MI (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FLNA
  • ABP-280
  • ABPX
  • FLN
  • XX-FW8312...
    		•  The BioGRID Database Seperator actin-binding protein 280|filamin 1|filamin A, alpha|otopalatodigital syndrome 1|otopalatodigital syndrome 2; filamin A, alpha (actin binding protein 280)
    Gene Ontology: [View List]
    Two-hybrid
    hit Tsuchiya H (1996)
    hit Zhou MI (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ATXN2
  • ATX2
  • FLJ46772
  • SCA2
  • EG6311
    		•  The BioGRID Database Seperator olivopontocerebellar ataxia 2, autosomal dominant|spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2, autosomal dominant, ataxin 2)|trinucleotide repeat containing 13; ataxin 2
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IMPDH2
  • IMPD2
  • IMPDH-II
  • EG3615
    		•  The BioGRID Database Seperator IMP dehydrogenase 2|IMP oxireductase 2|inosine 5' phosphate dehydrogenase 2|inosine monophosphate dehydrogenase 2|inosine monophosphate dehydrogenase type II|inosine monophosphate oxireductase 2; IMP (inosine monophosphate) dehydrogenase 2
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS9
  • XXbac-BCX...
    		•  The BioGRID Database Seperator 40S ribosomal protein S9; ribosomal protein S9
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HAS1
  • HAS
  • EG3036
    		•  The BioGRID Database Seperator hyaluronan synthase 1
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PCMT1
  • EG5110
    		•  The BioGRID Database Seperator protein-L-isoaspartate (D-aspartate) O-methyltransferase; L-isoaspartyl/D-aspartyl methyltransferase
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KNTC1
  • KIAA0166
  • ROD
  • FLJ36151
  • EG9735
    		•  The BioGRID Database Seperator Rough Deal (Drosophila) homolog, centromere/kinetochore protein|Rough Deal homolog, centromere/kinetochore protein|rough deal homolog; kinetochore associated 1
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPA3
  • REPA3
  • EG6119
    		•  The BioGRID Database Seperator replication protein A3, 14kDa; replication protein A3 (14kD)
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MCC
  • FLJ46755
  • MCC1
  • FLJ38893
  • EG4163
    		•  The BioGRID Database Seperator mutated in colorectal cancers
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CHMP2B
  • CHMP2.5
  • DKFZP564O...
  • DMT1
  • EG25978
    		•  The BioGRID Database Seperator charged multivesicular body protein 2b|vacuolar protein sorting 2-2; chromatin modifying protein 2B
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSTB
  • CST6
  • EPM1
  • PME
  • EG1476
    		•  The BioGRID Database Seperator CPI-B|cystatin B|liver thiol proteinase inhibitor|stefin B; cystatin B (stefin B)
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CSTF3
  • MGC75122
  • MGC43001
  • CSTF-77
  • EG1479
    		•  The BioGRID Database Seperator CSTF 77 kDa subunit|cleavage stimulation factor subunit 3|cleavage stimulation factor subunit 3, isoform 1; cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TPT1
  • FLJ27337
  • HRF
  • TCTP
  • EG7178
    		•  The BioGRID Database Seperator tumor protein, translationally-controlled 1; fortilin|histamine-releasing factor
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HDAC3
  • HD3
  • RPD3
  • RPD3-2
  • EG8841
    		•  The BioGRID Database Seperator histone deacetylase 3
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Mahon PC (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FN1
  • CIG
  • DKFZp686F...
  • DKFZp686H...
  • EG2335
    		•  The BioGRID Database Seperator cold-insoluble globulin|migration stimulating factor|migration-stimulating factor; fibronectin 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Ohh M (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CUL5
  • VACM-1
  • VACM1
  • EG8065
    		•  The BioGRID Database Seperator Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1)|Vasopressin-activated calcium-mobilizing receptor-1; cullin 5
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Kamura T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HNRPA2B1
  • HNRNPA2
  • HNRNPB1
  • HNRPA2
  • EG3181
    		•  The BioGRID Database Seperator heterogeneous nuclear ribonucleoprotein B1|nuclear ribonucleoprotein particle A2 protein; heterogeneous nuclear ribonucleoprotein A2/B1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Pioli PA (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HDAC2
  • RPD3
  • YAF1
  • EG3066
    		•  The BioGRID Database Seperator OTTHUMP00000040427|YY1-associated factor 1|transcriptional regulator homolog RPD3; histone deacetylase 2
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Mahon PC (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HDAC1
  • HD1
  • RPD3
  • RPD3L1
  • EG3065
    		•  The BioGRID Database Seperator reduced potassium dependency, yeast homolog-like 1; histone deacetylase 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Mahon PC (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PPIB
  • CYP-S1
  • CYPB
  • MGC14109
  • EG5479
    		•  The BioGRID Database Seperator PPIase|S-cyclophilin|cyclophilin B|cyclophilin-like protein|peptidyl-prolyl cis-trans isomerase B|peptidylprolyl isomerase B|rotamase; peptidylprolyl isomerase B (cyclophilin B)
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PIN1
  • DOD
  • UBL5
  • EG5300
    		•  The BioGRID Database Seperator peptidyl-prolyl cis/trans isomerase, NIMA-interacting|prolyl isomerase|protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRIM28
  • KAP1
  • RNF96
  • TF1B
  • EG10155
    		•  The BioGRID Database Seperator KRAB-associated protein 1|nuclear corepressor KAP-1|transcriptional intermediary factor 1-beta|tripartite motif-containing 28 protein; tripartite motif-containing 28
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Li Z (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HIF1AN
  • DKFZp762F...
  • FIH1
  • FLJ20615
  • EG55662
    		•  The BioGRID Database Seperator hypoxia-inducible factor 1, alpha subunit inhibitor; factor inhibiting HIF1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Mahon PC (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MRCL3
  • MLCB
  • MRLC3
  • EG10627
    		•  The BioGRID Database Seperator myosin regulatory light chain MRLC3|myosin, light polypeptide, regulatory, non-sarcomeric (20kD); myosin regulatory light chain MRCL3
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HIST1H2BC
  • H2B.1
  • H2B/l
  • H2BFL
  • EG8347
    		•  The BioGRID Database Seperator H2B histone family, member L|histone 1, H2bc; histone cluster 1, H2bc
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     APRT
  • AMP
  • DKFZp686D...
  • MGC125856
  • EG353
    		•  The BioGRID Database Seperator AMP diphosphorylase|AMP pyrophosphorylase|adenine phosphoribosyltransferase, isoform a|transphosphoribosidase; adenine phosphoribosyltransferase
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TXN
  • MGC61975
  • TRX
  • DKFZp686B...
  • EG7295
    		•  The BioGRID Database Seperator thioredoxin
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDK2
  • p33(CDK2)
  • EG1017
    		•  The BioGRID Database Seperator cdc2-related protein kinase|cell devision kinase 2|p33 protein kinase; cyclin-dependent kinase 2
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PKD1L3
  • EG342372
    		•  The BioGRID Database Seperator polycystic kidney disease 1-like 3; polycystin 1-like 3
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FSCN1
  • SNL
  • p55
  • FLJ38511
  • EG6624
    		•  The BioGRID Database Seperator Singed, drosophila, homolog-like|actin bundling protein|fascin 1|singed-like (fascin homolog, sea urchin); fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator