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VEGF
Homo sapiens
Aliases:
MGC70609, VEGFA, VPF, VEGF-A, EG7422
Description:
vascular endothelial growth factor A; vascular permeability factor
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
19 total GO annotations for this record.
[view list]
Function
Process
Component
•
heparin binding
(
IDA
)
•
extracellular matrix bind ...
(
NAS
)
•
vascular endothelial grow ...
(
TAS
)
•
protein binding
(
IPI
)
•
protein homodimerization ...
(
NAS
)
•
growth factor activity
(
NAS
)
•
vasculogenesis
(
TAS
)
•
response to hypoxia
(
IDA
)
•
negative regulation of ap ...
(
IMP
)
•
angiogenesis
(
NAS
)
•
signal transduction
(
TAS
)
•
response to stress
(
TAS
)
•
nervous system developmen ...
(
TAS
)
•
cell migration
(
NAS
)
•
positive regulation of va ...
(
NAS
)
•
induction of positive che ...
(
NAS
)
•
positive regulation of ce ...
(
TAS
)
•
extracellular space
(
TAS
)
•
proteinaceous extracellul ...
(
NAS
)
Download interactions associated with VEGF
VEGF was identified with
17
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
ADAMTS1
C3-C5
KIAA1346
METH1
EG9510
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1|human metalloproteinase with thrombospondin type 1 motifs; ADAM metallopeptidase with thrombospondin type 1 motif, 1
Gene Ontology:
[View List]
Co-purification
bait
Luque A (2003)
Affinity Capture-Western
bait
Luque A (2003)
Reconstituted Complex
bait
Luque A (2003)
NRP1
DKFZp686A...
DKFZp781F...
NRP
RP11-342D...
neuropilin-1|transmembrane receptor; neuropilin 1
Gene Ontology:
[View List]
Reconstituted Complex
bait
Mamluk R (2002)
bait
Soker S (1998)
Affinity Capture-Western
bait
Soker S (1998)
VEGF
MGC70609
VEGFA
VPF
EG7422
vascular endothelial growth factor A; vascular permeability factor
Gene Ontology:
[View List]
Co-purification
bait/hit
Eriksson A (2002)
hit
Keyt BA (1996)
Co-crystal Structure
hit
Muller YA (1997)
CTGF
CCN2
IGFBP8
MGC102839
EG1490
hypertrophic chondrocyte-specific protein 24|insulin-like growth factor-binding protein 8; connective tissue growth factor
Gene Ontology:
[View List]
Affinity Capture-Western
bait
Inoki I (2002)
Reconstituted Complex
hit
Inoki I (2002)
VTN
V75
VNT
VN
EG7448
complement S-protein|epibolin|serum spreading factor|somatomedin B|vitronectin (serum spreading factor, somatomedin B, complement S-protein); vitronectin
Gene Ontology:
[View List]
Reconstituted Complex
bait
Schoppet M (2002)
GPC1
FLJ38078
glypican
EG2817
glypican proteoglycan 1; glypican 1
Gene Ontology:
[View List]
Reconstituted Complex
hit
Gengrinovitch S (1999)
SPARC
ON
EG6678
cysteine-rich protein|osteonectin|secreted protein, acidic, cysteine-rich; secreted protein, acidic, cysteine-rich (osteonectin)
Gene Ontology:
[View List]
Far Western
bait
Kupprion C (1998)
IGFBP7
FSTL2
IGFBP-7
MAC25
EG3490
insulin-like growth factor binding protein 7
Gene Ontology:
[View List]
Reconstituted Complex
bait
Usui T (2002)
KDR
FLK1
VEGFR
VEGFR2
EG3791
kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2
Gene Ontology:
[View List]
Biochemical Activity
hit
Luque A (2003)
PGF
PLGF
PlGF-2
D12S1900
EG5228
placental growth factor, vascular endothelial growth factor-related protein; placental growth factor-like
Gene Ontology:
[View List]
Co-purification
bait/hit
Eriksson A (2002)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.