| Name |
Aliases |
 |
Description |
| Evidence Code |
| Role |
Source [Interactions] |
|
|
 |
| TP53 |
p53FLJ92943TRP53 |
 |
transformation-related protein 53
|
|
 |
 |
 |
| TRAF6 |
MGC:3310RNF85 |
 |
TNF receptor-associated factor 6
|
|
 |
 |
 |
| HIF1A |
HIF-1alphaPASD8MOP1 |
 |
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
|
 |
 |
 |
| EGFR |
ERBB1HER1ERBB |
 |
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
|
|
 |
 |
 |
| NFE2L2 |
NRF2 |
 |
nuclear factor (erythroid-derived 2)-like 2
|
|
 |
 |
 |
| MDM2 |
MGC5370MGC71221hdm2 |
 |
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein
|
|
 |
 |
 |
| RIPK1 |
RIPRIP1FLJ39204 |
 |
receptor (TNFRSF)-interacting serine-threonine kinase 1
|
|
 |
 |
 |
| IRAK1 |
IRAKpelle |
 |
interleukin-1 receptor-associated kinase 1
|
|
 |
 |
 |
| SCNN1G |
ENaCgSCNEGENaCgamma |
 |
amiloride-sensitive epithelial sodium channel gamma subunit
|
|
 |
 |
 |
| PCNA |
MGC8367 |
 |
DNA polymerase delta auxiliary protein
|
|
 |
 |
 |
| PARK2 |
PRKNPDJLPRS2 |
 |
Parkinson disease (autosomal recessive, juvenile) 2, parkin
|
|
 |
 |
 |
| SMURF2 |
MGC138150DKFZp686F... |
 |
SMAD specific E3 ubiquitin protein ligase 2
|
|
 |
 |
 |
| NOTCH1 |
hN1TAN1 |
 |
Notch homolog 1, translocation-associated (Drosophila)
|
|
 |
 |
 |
| DDX58 |
FLJ13599DKFZp686N...DKFZp434J... |
 |
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I
|
|
 |
 |
 |
| SCNN1A |
FLJ21883ENaCaENaCalpha |
 |
amiloride-sensitive epithelial sodium channel alpha subunit
|
|
 |
 |
 |
| SCNN1B |
ENaCbetaENaCbSCNEBhCG_23853 |
 |
amiloride-sensitive sodium channel subunit beta
|
|
 |
 |
 |
| CNTN2 |
TAG-1TAXAXT |
 |
transiently-expressed axonal glycoprotein
|
|
 |
 |
 |
| CBL |
C-CBLCBL2RNF55 |
 |
Cas-Br-M (murine) ecotropic retroviral transforming sequence
|
|
 |
 |
 |
| BIRC2 |
cIAP1c-IAP1RNF48 |
 |
baculoviral IAP repeat-containing protein 2
|
|
 |
 |
 |
| JUN |
AP1AP-1c-Jun |
 |
v-jun avian sarcoma virus 17 oncogene homolog
|
|
 |
 |
 |
| NF2 |
ACNBANFSCH |
 |
neurofibromin 2 (bilateral acoustic neuroma)
|
|
 |
 |
 |
| RNF125 |
FLJ20456TRAC1MGC21737 |
 |
T-cell ring protein identified in activation screen
|
|
 |
 |
 |
| UBA1 |
UBE1A1STGXP1CTD-2522E... |
 |
A1S9T and BN75 temperature sensitivity complementing
|
|
 |
 |
 |
| SMURF1 |
KIAA1625 |
 |
SMAD specific E3 ubiquitin protein ligase 1
|
|
 |
 |
 |
| CDC2 |
CDK1DKFZp686L...MGC111195 |
 |
cell division cycle 2, G1 to S and G2 to M
|
|
 |
 |
 |
| KEAP1 |
MGC10630INrf2KIAA0132 |
 |
kelch-like ECH-associated protein 1
|
|
 |
 |
 |
| EEF1A1 |
FLJ25721LENG7MGC16224RP11-505P... |
 |
eukaryotic translation elongation factor 1 alpha 1-like 14
|
|
 |
 |
 |
| TTYH2 |
MGC4837MGC126172C17orf29 |
 |
tweety homolog 2 (Drosophila)
|
|
 |
 |
 |
| PELI3 |
MGC35521 |
 |
pellino homolog 3 (Drosophila)
|
|
 |
 |
 |
| CDKN1A |
MDA-6CAP20P21 |
 |
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
|
|
 |
 |
 |
| NFKB2 |
LYT-10LYT10p52 |
 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
|
|
 |
 |
 |
| MET |
c-MetHGFRAUTS9 |
 |
met proto-oncogene (hepatocyte growth factor receptor)
|
|
 |
 |
 |
| E2F1 |
RBBP3E2F-1RBP3 |
 |
retinoblastoma-associated protein 1
|
|
 |
 |
 |
| ERBB4 |
MGC138404HER4p180erbB4 |
 |
avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4
|
|
 |
 |
 |
| IGF1R |
MGC142170CD221JTK13 |
 |
insulin-like growth factor 1 receptor
|
|
 |
 |
 |
| BRCA1 |
RNF53IRISBRCC1 |
 |
breast and ovarian cancer susceptibility protein 1
|
|
 |
 |
 |
| USP5 |
ISOT |
 |
ubiquitin-specific protease-5 (ubiquitin isopeptidase T)
|
|
 |
 |
 |
| SMAD3 |
MGC60396HSPC193MADH3 |
 |
MAD, mothers against decapentaplegic homolog 3
|
|
 |
 |
 |
| PLCG1 |
PLC148PLC1PLC-II |
 |
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1
|
|
 |
 |
 |
| NUAK1 |
ARK5KIAA0537 |
 |
AMP-activated protein kinase family member 5
|
|
 |
 |
 |
| MARK4 |
KIAA1860Nbla00650MARKL1 |
 |
MAP/microtubule affinity-regulating kinase like 1
|
|
 |
 |
 |
| HDAC3 |
RPD3-2RPD3HD3 |
 |
histone deacetylase 3
|
|
 |
 |
 |
| NEDD4 |
NEDD4-1MGC176705RPF1 |
 |
neural precursor cell expressed, developmentally down-regulated 4
|
|
 |
 |
 |
| RELA |
NFKB3MGC131774p65 |
 |
v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65))
|
|
 |
 |
 |
| THRA |
MGC000261AR7THRA1 |
 |
thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
|
|
 |
 |
 |
| LAT |
pp36LAT1 |
 |
linker for activation of T-cells family member 1
|
|
 |
 |
 |
| CD4 |
CD4mut |
 |
CD4 antigen (p55)
|
|
 |
 |
 |
| NR1H3 |
RLD-1LXR-aTLS/CHOP |
 |
nuclear receptor subfamily 1, group H, member 3
|
|
 |
 |
 |
| CXCR4 |
NPYRLCD184HM89 |
 |
leukocyte-derived seven-transmembrane-domain receptor
|
|
 |
 |
 |
| CFTR |
TNR-CFTRCFdJ760C5.1tcag7.78 |
 |
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
|
|
 |
 |
 |
| TRPV4 |
VRL2VRL-2TRP12 |
 |
transient receptor potential cation channel, subfamily V, member 4
|
|
 |
 |
 |
| HIBADH |
NS5ATP1MGC40361 |
 |
3'-hydroxyisobutyrate dehydrogenase
|
|
 |
 |
 |
| IRF1 |
MARIRF-1 |
 |
interferon regulatory factor 1
|
|
 |
 |
 |
| BCL3 |
BCL4D19S37 |
 |
chronic lymphatic leukemia protein
|
|
 |
 |
 |
| MAPKAPK5 |
PRAK |
 |
mitogen-activated protein kinase-activated protein kinase 5
|
|
 |
 |
 |
| MAPKAPK3 |
3PKMAPKAP3 |
 |
mitogen-activated protein kinase-activated protein kinase 3
|
|
 |
 |
 |
| NLK |
FLJ21033DKFZp761G... |
 |
nemo-like kinase
|
|
 |
 |
 |
| RFC2 |
MGC3665RFC40A1 |
 |
replication factor C (activator 1) 2, 40kDa
|
|
 |
 |
 |
| GPI |
SA36NLKPHI |
 |
hexose monophosphate isomerase
|
|
 |
 |
 |
| KCNN4 |
KCa3.1hKCa4IK1 |
 |
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
|
|
 |
 |
 |
| SOCS1 |
CIS1TIP3SSI-1 |
 |
suppressor of cytokine signaling 1
|
|
 |
 |
 |
| GMEB1 |
P96PIFPIF96 |
 |
glucocorticoid modulatory element binding protein 1
|
|
 |
 |
 |
| CKM |
CKMMM-CK |
 |
creatine kinase, muscle
|
|
 |
 |
 |
| IKBKG |
NEMOIPD2IP2 |
 |
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
|
|
 |
 |
 |
| AGL |
GDE |
 |
amylo-1, 6-glucosidase, 4-alpha-glucanotransferase
|
|
 |
 |
 |
| TRAF2 |
MGC:45012TRAP3TRAP |
 |
tumor necrosis factor type 2 receptor associated protein 3
|
|
 |
 |
 |
| ESR2 |
ER-BETAESTRBESRB |
 |
estrogen receptor 2 (ER beta)
|
|
 |
 |
 |
| Ntrk1 |
Trk |
 |
neurotrophic tyrosine kinase, receptor, type 1
|
|
 |
 |
 |
| Sqstm1 |
OsiZIP3ZIP |
 |
induced oxidative stress-like
|
|
 |
 |
 |
| USP3 |
MGC129878MGC129879SIH003 |
 |
ubiquitin-specific-processing protease 3
|
|
 |
 |
 |
| DLG1 |
DLGH1DKFZp761P...DKFZp781B... |
 |
discs, large homolog 1 (Drosophila)
|
|
 |
 |
 |
| TRIM32 |
HT2ALGMD2HTATIPRP11-67K1... |
 |
tripartite motif-containing 32
|
|
 |
 |
 |
| BACH1 |
BACH-1 |
 |
BTB and CNC homology 1, basic leucine zipper transcription factor 1
|
|
 |
 |
 |
| GUCY1A2 |
GUC1A2GC-SA2 |
 |
guanylate cyclase 1, soluble, alpha 2
|
|
 |
 |
 |
| TRAF3 |
LAP1CAP-1CD40bp |
 |
CD40 receptor associated factor 1
|
|
 |
 |
 |
| OTUD5 |
MGC104871DKFZp761A...DUBA |
 |
OTU domain containing 5
|
|
 |
 |
 |
| PIAS3 |
ZMIZ5FLJ14651 |
 |
protein inhibitor of activated STAT, 3
|
|
 |
 |
 |
| AR |
SBMANR3C4SMAX1RP11-383C... |
 |
dihydrotestosterone receptor
|
|
 |
 |
 |
| TRIOBP |
FLJ39315TARAdJ37E16.4 |
 |
TRIO and F-actin binding protein
|
|
 |
 |
 |
| TP63 |
p73Lp40p73H |
 |
chronic ulcerative stomatitis protein
|
|
 |
 |
 |
| MAGEA11 |
MGC10511MAGE11CT1.11 |
 |
cancer/testis antigen family 1, member 11
|
|
 |
 |
 |
| TAL1 |
TCL5SCLbHLHa17 |
 |
T-cell acute lymphocytic leukemia 1
|
|
 |
 |
 |
| OPRK1 |
KOROPRK |
 |
opioid receptor, kappa 1
|
|
 |
 |
 |
| ARHGEF9 |
COLLYBISTINPEM-2HPEM-2RP11-357C... |
 |
Cdc42 guanine nucleotide exchange factor (GEF) 9
|
|
 |
 |
 |
| AQP2 |
WCH-CDMGC34501AQP-CD |
 |
collecting duct water channel protein
|
|
 |
 |
 |
| PPARGC1A |
PGC1APPARGC1PGC1 |
 |
peroxisome proliferative activated receptor, gamma, coactivator 1, alpha
|
|
 |
 |
 |
| AIFM1 |
MGC111425PDCD8AIFRP3-438D1... |
 |
apoptosis-inducing factor, mitochondrion-associated, 1
|
|
 |
 |
 |
| VCP |
MGC131997MGC148092IBMPFD |
 |
transitional endoplasmic reticulum ATPase
|
|
 |
 |
 |
| HIST2H2BE |
H2BGL105H2B.1H2B |
 |
H2B histone family, member Q
|
|
 |
 |
 |
| GRIN2B |
NMDAR2BNR2BMGC142178 |
 |
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
|
|
 |
 |
 |
| TP73 |
P73 |
 |
p53-like transcription factor
|
|
 |
 |
 |
| ETS1 |
EWSR2FLJ10768ETS-1 |
 |
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
|
|
 |
 |
 |
| FANCI |
KIAA1794FLJ10719 |
 |
Fanconi anemia, complementation group I
|
|
 |
 |
 |
| CHFR |
FLJ33629RNF196FLJ10796 |
 |
checkpoint with forkhead and ring finger domains
|
|
 |
 |
 |
| ESR1 |
EREraNR3A1RP1-130E4.1 |
 |
estrogen receptor alpha
|
|
 |
 |
 |
| SOS1 |
NS4GF1HGF |
 |
son of sevenless homolog 1 (Drosophila)
|
|
 |
 |
 |
| RASGRF1 |
GRF1PP13187CDC25L |
 |
Ras-specific guanine nucleotide-releasing factor, CDC25 homolog
|
|
 |
 |
 |
| GLP1R |
MGC138331 |
 |
glucagon-like peptide 1 receptor
|
|
 |
 |
 |
| GIPR |
MGC126722 |
 |
gastric inhibitory polypeptide receptor
|
|
 |
 |
 |
| USP16 |
UBP-M |
 |
ubiquitin-specific processing protease 16
|
|
 |
 |
 |
| UIMC1 |
X2HRIP110RAP80 |
 |
ubiquitin interaction motif containing 1
|
|
 |
 |
 |
| HDAC6 |
JM21HD6FLJ16239 |
 |
histone deacetylase 6
|
|
 |
 |
 |
| LIMK1 |
LIMK |
 |
LIM motif-containing protein kinase
|
|
 |
 |
 |
| AIMP2 |
JTV1PRO0992JTV-1 |
 |
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
|
|
 |
 |
 |
| BSCL2 |
MGC4694HMN5GNG3LG |
 |
Bernardinelli-Seip congenital lipodystrophy 2 (seipin)
|
|
 |
 |
 |
| RNF41 |
MGC45228NRDP1SBBI03 |
 |
neuregulin receptor degradation protein-1
|
|
 |
 |
 |
| SYVN1 |
HRD1KIAA1810MGC40372 |
 |
synovial apoptosis inhibitor 1, synoviolin
|
|
 |
 |
 |
| FASLG |
APT1LG1CD178CD95L |
 |
tumor necrosis factor (ligand) superfamily, member 6
|
|
 |
 |
 |
| RNF2 |
BAP1RING2HIPI3GS1-120K1... |
 |
ring finger protein 2
|
|
 |
 |
 |
| MLH1 |
FCC2HNPCChMLH1 |
 |
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
|
|
 |
 |
 |
| PMS1 |
PMSL1hPMS1DKFZp781M... |
 |
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
|
|
 |
 |
 |
| PMS2 |
PMSL2PMS2CLHNPCC4 |
 |
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
|
|
 |
 |
 |
| MCF2 |
DBLRP6-88D7.2 |
 |
MCF.2 cell line derived transforming sequence
|
|
 |
 |
 |
| RELB |
REL-BIRELI-REL |
 |
v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
|
|
 |
 |
 |
| Sgce |
e-SG |
 |
sarcoglycan, epsilon
|
|
 |
 |
 |
| ERBB3 |
MDA-BF-1p85-sErbB3c-erbB-3 |
 |
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
|
|
 |
 |
 |
| CYBA |
p22-PHOX |
 |
flavocytochrome b-558 alpha polypeptide
|
|
 |
 |
 |
| DDX39 |
BAT1LDDXLURH49 |
 |
nuclear RNA helicase, DECD variant of DEAD box family
|
|
 |
 |
 |
| CCNE1 |
CCNE |
 |
cyclin E1
|
|
 |
 |
 |
| MUSK |
MGC126323MGC126324RP11-104M... |
 |
muscle, skeletal, receptor tyrosine kinase
|
|
 |
 |
 |
| PHLPP1 |
PLEKHE1MGC161555PHLPP |
 |
pleckstrin homology domain containing, family E (with leucine rich repeats) member 1
|
|
 |
 |
 |
| SNCA |
PARK1MGC110988PD1 |
 |
synuclein, alpha (non A4 component of amyloid precursor)
|
|
 |
 |
 |
| GFI1 |
FLJ94509ZNF163GFI-1 |
 |
growth factor independent 1 transcription repressor
|
|
 |
 |
 |
| PSEN2 |
AD3LAD4PS2 |
 |
presenilin 2 (Alzheimer disease 4)
|
|
 |
 |
 |
| Cd4 |
W3/25p55 |
 |
Cd4 molecule
|
|
 |
 |
 |
| HSPA4 |
hsp70RYRYMGC131852 |
 |
heat shock protein, 110 kDa
|
|
 |
 |
 |
| MAP3K5 |
MAPKKK5MEKK5ASK1RP3-325F2... |
 |
mitogen-activated protein kinase kinase kinase 5
|
|
 |
 |
 |
| TSC1 |
MGC86987TSCLAM |
 |
tuberous sclerosis 1 protein
|
|
 |
 |
 |
| PAX7 |
FLJ37460HUP1PAX7B |
 |
PAX7 transcriptional factor
|
|
 |
 |
 |
| MCL1 |
Mcl-1MGC104264MCL1L |
 |
induced myeloid leukemia cell differentiation protein Mcl-1
|
|
 |
 |
 |
| IRAK4 |
IPD1REN64NY-REN-64 |
 |
interleukin-1 receptor-associated kinase 4
|
|
 |
 |
 |
| Arrb2 |
MGC105502BARRES |
 |
arrestin, beta 2
|
|
 |
 |
 |
| SOD1 |
homodimerIPOAALS |
 |
superoxide dismutase 1, soluble
|
|
 |
 |
 |
| PAX3 |
MGC120383MGC120381CDHS |
 |
paired box homeotic gene 3
|
|
 |
 |
 |
| TANK |
I-TRAFTRAF2 |
 |
TRAF family member-associated NF-KAPPA-B activator
|
|
 |
 |
 |
| CRTC2 |
TORC2RP11-422P... |
 |
transducer of regulated cAMP response element-binding protein (CREB) 2
|
|
 |
 |
 |
| CSF1 |
MCSFMGC31930 |
 |
colony stimulating factor 1 (macrophage)
|
|
 |
 |
 |
| ETHE1 |
YF13H12HSCO |
 |
ethylmalonic encephalopathy 1
|
|
 |
 |
 |
| IL17RA |
MGC10262CDw217IL17R |
 |
interleukin 17 receptor A
|
|
 |
 |
 |
| NHLRC1 |
MALINbA204B7.2EPM2A |
 |
epilepsy, progressive myoclonus type 2B
|
|
 |
 |
 |
| MAPK1 |
ERKERK2MAPK2 |
 |
extracellular signal-regulated kinase 2
|
|
 |
 |
 |
| EPM2A |
MELFEPM2RP1-28C20.2 |
 |
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
|
|
 |
 |
 |
| IRF8 |
ICSBP1ICSBPIRF-8 |
 |
interferon consensus sequence binding protein 1
|
|
 |
 |
 |
| UBA6 |
UBE1L2MOP-4FLJ23367 |
 |
ubiquitin-like modifier activating enzyme 6
|
|
 |
 |
 |
| RHOA |
RHOH12ARHARHO12 |
 |
ras homolog gene family, member A
|
|
 |
 |
 |
| COPE |
epsilon-COPFLJ13241 |
 |
epsilon subunit of coatomer protein complex
|
|
 |
 |
 |
| RSP5 |
UBY1SMM1MUT2YER125W |
 |
Ubiquitin-protein ligase involved in ubiquitin-mediated protein degradation; functions in multivesicular body sorting, heat shock response and ubiquitylation of arrested RNAPII; contains a hect (homologous to E6-AP carboxyl terminus) domain
|
|
 |
 |
 |
| ITCH |
dJ468O1.1AIP4AIF4 |
 |
dJ468O1.1 (atrophin 1 interacting protein 4 (AIP4))
|
|
 |
 |
 |
| WWP2 |
AIP2WWp2-like |
 |
WW domain containing E3 ubiquitin protein ligase 2
|
|
 |
 |
 |
| HMGCR |
LDLCQ3 |
 |
3-hydroxy-3-methylglutaryl CoA reductase (NADPH)
|
|
 |
 |
 |
| TARDBP |
TDP-43ALS10RP4-635E1... |
 |
TAR DNA-binding protein-43
|
|
 |
 |
 |
| SNX3 |
Grd19SDP3MGC17570RP3-429G5.4 |
 |
sorting nexin 3A
|
|
 |
 |
 |
| AXIN1 |
MGC52315AXINLA16c-314... |
 |
axis inhibition protein 1
|
|
 |
 |
 |
| ABI2 |
ABI2BargBPIAAblBP3 |
 |
abl-interacting protein 1 (SH3-containing protein)
|
|
 |
 |
 |
| CDH1 |
Arc-1CDHELCAM |
 |
calcium-dependent adhesion protein, epithelial
|
|
 |
 |
 |
| ATXN3 |
JOSSCA3MJD1 |
 |
Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3)
|
|
 |
 |
 |
| WRNIP1 |
bA420G6.2RP11-420G...FLJ22526 |
 |
Werner helicase interacting protein 1
|
|
 |
 |
 |
| IKBKE |
MGC125295MGC125294IKKERP11-534L... |
 |
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
|
 |
 |
 |
| TBK1 |
NAKT2KFLJ11330 |
 |
NF-kB-activating kinase
|
|
 |
 |
 |
| LIG1 |
MGC117397MGC130025 |
 |
polydeoxyribonucleotide synthase ATP 1
|
|
 |
 |
 |
| HNRNPK |
TUNPCSBPFLJ41122 |
 |
transformation upregulated nuclear protein
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| RBM27 |
Psc1ARRS1KIAA1311 |
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acidic rich RS domain containing 1
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| ARNTL |
BMAL1cTICBMAL1 |
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aryl hydrocarbon receptor nuclear translocator-like
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| CD40LG |
IGMCD154hCD40LRP3-527F8.3 |
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tumor necrosis factor (ligand) superfamily member 5
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| NCOA3 |
TRAM-1SRC3CAGH16RP5-1049G... |
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