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BioGRID | Network Layout for TSC1 for Homo sapiens
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TSC1

 Homo sapiens
The BioGRID Database Seperator
Aliases: KIAA0243, LAM, MGC86987, TSC, EG7248
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: hamartin|tuberous sclerosis 1 protein|tumor suppressor; tuberous sclerosis 1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 21 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with TSC1

TSC1 was identified with 46 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 TSC2
  • LAM
  • TSC4
  • FLJ43106
  • EG7249
    		•  The BioGRID Database Seperator tuberous sclerosis 2; tuberin
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Dan HC (2002)
    bait/hit Hodges AK (2001)
    bait/hit Aicher LD (2001)
    bait/hit van Slegtenhorst M (1998)
    bait Li Y (2004)
    bait Mak BC (2003)
    bait/hit Ma L (2005)
    bait Cai SL (2006)
    bait/hit Cao Y (2006)
    hit Inoki K (2003)
    hit Goncharova EA (2006)
    hit Astrinidis A (2006)
    hit Astrinidis A (2003)
    hit Nellist M (2001)
    hit Benvenuto G (2000)
    hit Murthy V (2000)
    hit Miloloza A (2000)
    Two-hybrid
    bait Nellist M (2002)
    bait van Slegtenhorst M (1998)
    hit Shumway SD (2003)
    hit Hodges AK (2001)
    Co-localization
    bait van Slegtenhorst M (1998)
    Affinity Capture-MS
    hit Nellist M (2005)
    Co-purification
    hit Nellist M (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAA
  • EG7527
    		•  The BioGRID Database Seperator tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide; 14-3-3 alpha
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Nellist M (2002)
    bait Shumway SD (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AKT1
  • MGC99656
  • PKB
  • PRKBA
  • EG207
    		•  The BioGRID Database Seperator RAC-alpha serine/threonine-protein kinase|murine thymoma viral (v-akt) oncogene homolog-1|protein kinase B|rac protein kinase alpha; v-akt murine thymoma viral oncogene homolog 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Roux PP (2004)
    bait Dan HC (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NEFL
  • CMT1F
  • CMT2E
  • NF-L
  • EG4747
    		•  The BioGRID Database Seperator neurofilament, light polypeptide (68kD); neurofilament, light polypeptide 68kDa
    Gene Ontology: [View List]
    Two-hybrid
    hit Haddad LA (2002)
    Affinity Capture-Western
    bait Haddad LA (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTK2
  • FADK
  • FAK
  • FAK1
  • EG5747
    		•  The BioGRID Database Seperator PTK2 protein tyrosine kinase 2; focal adhesion kinase 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Gan B (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAM
  • PAL
  • PHM
  • EG5066
    		•  The BioGRID Database Seperator pancreatic peptidylglycine alpha-amidating monooxygenase|peptidyl alpha-amidating enzyme|peptidyl-alpha-hydroxyglycine alpha-amidating lyase|peptidylglycine 2-hydroxylase|peptidylglycine alpha-hydroxylating monooxygenase; peptidylglycine alpha-amidating monooxygenase
    Gene Ontology: [View List]
    Co-localization
    bait Murthy V (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TSC1
  • KIAA0243
  • LAM
  • MGC86987
  • EG7248
    		•  The BioGRID Database Seperator hamartin|tuberous sclerosis 1 protein|tumor suppressor; tuberous sclerosis 1
    Gene Ontology: [View List]
    Two-hybrid
    hit Nellist M (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DOCK7
  • KIAA1771
  • ZIR2
  • EG85440
    		•  The BioGRID Database Seperator dedicator of cytokinesis 7
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Nellist M (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GSK3B
  • EG2932
    		•  The BioGRID Database Seperator glycogen synthase kinase 3 beta; GSK3beta isoform
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Mak BC (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Tsc2
  • Rc
  • EG24855
    		•  The BioGRID Database Seperator Tuberous sclerosis 2, (renal carcinoma)|renal carcinoma; tuberous sclerosis 2
    Gene Ontology: [View List]
    Co-localization
    bait Yamamoto Y (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AXIN1
  • AXIN
  • MGC52315
  • LA16c-314...
    		•  The BioGRID Database Seperator axis inhibition protein 1|axis inhibitor 1|fused, mouse, homolog of; axin 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Mak BC (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC2
  • CDK1
  • DKFZp686L...
  • MGC111195
  • EG983
    		•  The BioGRID Database Seperator cell cycle controller CDC2|cell division control protein 2 homolog|cell division cycle 2 protein|cyclin-dependent kinase 1|p34 protein kinase; cell division cycle 2, G1 to S and G2 to M
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Astrinidis A (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ACTA1
  • ACTA
  • ASMA
  • NEM1
  • EG58
    		•  The BioGRID Database Seperator alpha 1 actin|alpha skeletal muscle actin; actin, alpha 1, skeletal muscle
    Gene Ontology: [View List]
    Co-localization
    hit Lamb RF (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VIL2
  • CVIL
  • CVL
  • DKFZp762H...
  • EG7430
    		•  The BioGRID Database Seperator cytovillin 2|villin 2 (ezrin); ezrin
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Lamb RF (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAZ
  • KCIP-1
  • MGC111427
  • MGC126532
  • EG7534
    		•  The BioGRID Database Seperator 14-3-3 protein/cytosolic phospholipase A2|14-3-3 zeta|phospholipase A2|protein kinase C inhibitor protein-1|tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
    Gene Ontology: [View List]
    Two-hybrid
    hit Nellist M (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PLK1
  • PLK
  • STPK13
  • EG5347
    		•  The BioGRID Database Seperator cell cycle regulated protein kinase|polo (Drosophia)-like kinase|polo like kinase|polo-like kinase; polo-like kinase 1 (Drosophila)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Astrinidis A (2006)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RHEB
  • RHEB2
  • MGC111559
  • EG6009
    		•  The BioGRID Database Seperator GTP-binding protein Rheb|Ras homolog enriched in brain 2; Ras homolog enriched in brain
    Gene Ontology: [View List]
    Biochemical Activity
    hit Garami A (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MSN
  • EG4478
    		•  The BioGRID Database Seperator moesin
    Gene Ontology: [View List]
    Two-hybrid
    bait Haddad LA (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPS6KA1
  • HU-1
  • MAPKAPK1A
  • RSK
  • EG6195
    		•  The BioGRID Database Seperator dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1)|p90-RSK 1|ribosomal protein S6 kinase alpha 1|ribosomal protein S6 kinase, 90kD, 1|ribosomal protein S6 kinase, 90kD, polypeptide 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    hit Roux PP (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDKN1B
  • CDKN4
  • KIP1
  • P27KIP1
  • EG1027
    		•  The BioGRID Database Seperator cyclin-dependent kinase inhibitor 1B (p27, Kip1); cyclin-dependent kinase inhibitor 1B
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Rosner M (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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