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BioGRID | Network Layout for TOP2A for Homo sapiens
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TOP2A

 Homo sapiens
The BioGRID Database Seperator
Aliases: TOP2, TP2A, EG7153
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: DNA topoisomerase II, 170 kD|DNA topoisomerase II, alpha isozyme|topoisomerase (DNA) II alpha (170kD); topoisomerase (DNA) II alpha 170kDa
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 25 total GO annotations for this record. [view list]
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PIXEL
The BioGRID Database Seperator
Download interactions associated with TOP2A

TOP2A was identified with 16 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 HDAC1
  • HD1
  • RPD3
  • RPD3L1
  • EG3065
    		•  The BioGRID Database Seperator reduced potassium dependency, yeast homolog-like 1; histone deacetylase 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Tsai SC (2000)
    bait Johnson CA (2001)
    Reconstituted Complex
    bait/hit Johnson CA (2001)
    Two-hybrid
    hit Johnson CA (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TP53
  • TRP53
  • p53
  • LFS1
  • EG7157
    		•  The BioGRID Database Seperator tumor protein p53 (Li-Fraumeni syndrome); p53 tumor suppressor|tumor protein p53
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Cowell IG (2000)
    Reconstituted Complex
    bait Cowell IG (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SUMO1
  • GMP1
  • PIC1
  • SENP2
  • EG7341
    		•  The BioGRID Database Seperator GAP modifying protein 1|SMT3 suppressor of mif two 3 homolog 1|sentrin|ubiquitin-like 1 (sentrin); SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Mao Y (2000)
    Reconstituted Complex
    bait Mao Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DFFB
  • CAD
  • CPAN
  • DFF-40
  • EG1677
    		•  The BioGRID Database Seperator DNA fragmentation factor, 40 kD, beta polypeptide|DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase)|DNA fragmentation factor, 40 kD, beta subunit|caspase-activated deoxyribonuclease|caspase-activated nuclease; DNA fragmentation factor, 40kDa, beta polype...
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Durrieu F ()
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAE
  • 14-3-3E
  • KCIP-1
  • MDCR
  • EG7531
    		•  The BioGRID Database Seperator 14-3-3 epsilon|mitochondrial import stimulation factor L subunit|protein kinase C inhibitor protein-1|tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kurz EU (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JUN
  • AP1
  • c-Jun
  • EG3725
    		•  The BioGRID Database Seperator Jun activation domain binding protein|activator protein 1|enhancer-binding protein AP1|v-jun avian sarcoma virus 17 oncogene homolog|v-jun sarcoma virus 17 oncogene homolog; jun oncogene
    Gene Ontology: [View List]
    Far Western
    bait Kroll DJ (1993)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     XRCC5
  • KARP-1
  • KARP1
  • KU80
  • EG7520
    		•  The BioGRID Database Seperator ATP-dependent DNA helicase II|DNA repair protein XRCC5|Ku86 autoantigen related protein 1|X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kD)|X-ray repair, complementing defective, repair in Chinese hamster; X-ray repair...
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Matheos D (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HDAC2
  • RPD3
  • YAF1
  • EG3066
    		•  The BioGRID Database Seperator OTTHUMP00000040427|YY1-associated factor 1|transcriptional regulator homolog RPD3; histone deacetylase 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Tsai SC (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PIN1
  • DOD
  • UBL5
  • EG5300
    		•  The BioGRID Database Seperator peptidyl-prolyl cis/trans isomerase, NIMA-interacting|prolyl isomerase|protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Messenger MM (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TOP2B
  • TOPIIB
  • top2beta
  • EG7155
    		•  The BioGRID Database Seperator DNA topoisomerase II beta|DNA topoisomerase II, 180 kD|DNA topoisomerase II, beta isozyme|U937 associated antigen|antigen MLAA-44|topo II beta|topoisomerase (DNA) II beta (180kD)|topoisomerase II beta|topoisomerase IIb; topoisomerase (DNA) II beta 180kDa
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Biersack H (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DHX9
  • DDX9
  • LKP
  • NDH II
  • EG1660
    		•  The BioGRID Database Seperator ATP-dependent RNA helicase A|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 9 (RNA helicase A)|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 9 (RNA helicase A, nuclear DNA helicase II; leukophysin)|DEAD/H box-9 (nuclear DNA helicase II; RNA helicase A)|leukophysin; DEAH (Asp-Glu-Ala...
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Zhou K (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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    BioGRID: A General Repository for Interaction Datasets.
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