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BioGRID | Network Layout for STAT3 for Homo sapiens
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STAT3

 Homo sapiens
The BioGRID Database Seperator
Aliases: APRF, FLJ20882, MGC16063, EG6774
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: DNA-binding protein APRF|acute-phase response factor|signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor)
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 11 total GO mappings for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with STAT3

STAT3 was identified with 109 protein interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 RET
  • CDHF12
  • HSCR1
  • MEN2A
  • EG5979
    		•  The BioGRID Database Seperator Hirschsprung disease 1|RET transforming sequence|cadherin family member 12|hydroxyaryl-protein kinase|multiple endocrine neoplasia and medullary thyroid carcinoma 1|oncogene RET|receptor tyrosine kinase|ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung...
    Gene Ontology: [View List]
    Invivo
    bait Schuringa JJ (2001)
    Invitro
    bait Schuringa JJ (2001)
    Affinity Capture-MS
    bait Rual JF (2005)
    Affinity Capture-Western
    bait Yuan ZL (2004)
    bait Hwang JH (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AR
  • AIS
  • DHTR
  • HUMARA
  • RP11-383C...
    		•  The BioGRID Database Seperator androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease); OTTHUMP00000061928|androgen receptor|dihydrotestosterone receptor
    Gene Ontology: [View List]
    Invivo
    bait Ueda T (2002)
    Invitro
    bait Ueda T (2002)
    Affinity Capture-Western
    bait Matsuda T (2001)
    Reconstituted Complex
    bait Ueda T (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RPA2
  • REPA2
  • RPA32
  • EG6118
    		•  The BioGRID Database Seperator replication protein A2, 32kDa; replication protein A2 (32kD)
    Gene Ontology: [View List]
    Invivo
    bait Kim J (2000)
    Invitro
    bait Kim J (2000)
    Two-hybrid
    bait Kim J (2000)
    Affinity Capture-MS
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAT1
  • DKFZp686B...
  • ISGF-3
  • STAT91
  • EG6772
    		•  The BioGRID Database Seperator signal transducer and activator of transcription 1|signal transducer and activator of transcription-1|transcription factor ISGF-3 components p91/p84; signal transducer and activator of transcription 1, 91kDa
    Gene Ontology: [View List]
    Invivo
    hit Xia L (2002)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Affinity Capture-Western
    hit Gunaje JJ (2001)
    bait Spiekermann K (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAC1
  • MIG5
  • TC-25
  • p21-Rac1
  • EG5879
    		•  The BioGRID Database Seperator migration-inducing gene 5|migration-inducing protein 5|ras-related C3 botulinum toxin substrate 1|ras-related C3 botulinum toxin substrate 1 isoform Rac1b|rho family, small GTP binding protein Rac1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
    Gene Ontology: [View List]
    Invivo
    bait Simon AR (2000)
    Two-hybrid
    bait Simon AR (2000)
    Affinity Capture-MS
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TSLP
  • EG85480
    		•  The BioGRID Database Seperator thymic stromal lymphopoietin
    Gene Ontology: [View List]
    Invivo
    bait Reche PA (2001)
    bait Isaksen DE (1999)
    Affinity Capture-MS
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RELA
  • NFKB3
  • MGC131774
  • EG5970
    		•  The BioGRID Database Seperator v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65))|v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; v-rel reticuloendotheliosis...
    Gene Ontology: [View List]
    Invivo
    bait Yu Z (2002)
    Invitro
    bait Yu Z (2002)
    Affinity Capture-MS
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRIM19
  • NDUFA13
  • B16.6
  • CDA016
  • EG51079
    		•  The BioGRID Database Seperator NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13; cell death-regulatory protein GRIM19
    Gene Ontology: [View List]
    Two-hybrid
    bait Zhang J (2003)
    Affinity Capture-MS
    hit Rual JF (2005)
    Affinity Capture-Western
    hit Zhang J (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PDIA3
  • ERp57
  • ERp60
  • ERp61
  • EG2923
    		•  The BioGRID Database Seperator 58 kDa microsomal protein|endoplasmic reticulum P58|glucose regulated protein, 58kDa|phospholipase C-alpha|protein disulfide isomerase-associated 3; protein disulfide isomerase family A, member 3
    Gene Ontology: [View List]
    Invitro
    bait Guo GG (2002)
    Invivo
    bait Guo GG (2002)
    Affinity Capture-MS
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRC
  • ASV
  • SRC1
  • c-SRC
  • EG6714
    		•  The BioGRID Database Seperator proto-oncogene tyrosine-protein kinase SRC|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
    Gene Ontology: [View List]
    Invitro
    bait Cao X (1996)
    Invivo
    bait Cao X (1996)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TSHR
  • LGR3
  • MGC75129
  • hTSHR-I
  • EG7253
    		•  The BioGRID Database Seperator seven transmembrane helix receptor|thyroid stimulating hormone receptor, isoform 2|thyrotropin receptor|thyrotropin receptor-I, hTSHR-I; thyroid stimulating hormone receptor
    Gene Ontology: [View List]
    Invivo
    bait Park ES (2000)
    Invitro
    bait Park ES (2000)
    Affinity Capture-MS
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NR3C1
  • GCR
  • GR
  • GRL
  • EG2908
    		•  The BioGRID Database Seperator nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); glucocorticoid receptor|nuclear receptor subfamily 3, group C, member 1
    Gene Ontology: [View List]
    Invivo
    bait Zhang Z (1997)
    Affinity Capture-MS
    bait/hit Rual JF (2005)
    Reconstituted Complex
    bait Lerner L (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STATIP1
  • ELP2
  • FLJ10879
  • SHINC-2
  • EG55250
    		•  The BioGRID Database Seperator elongator protein 2|signal transducer and activator of transcription 3 interacting protein 1|signal transducer and activator of transcription interacting protein 1; elongation protein 2 homolog (S. cerevisiae)
    Gene Ontology: [View List]
    Two-hybrid
    hit Collum RG (2000)
    Reconstituted Complex
    bait Collum RG (2000)
    Affinity Capture-Western
    bait Collum RG (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JUN
  • AP1
  • c-Jun
  • EG3725
    		•  The BioGRID Database Seperator Jun activation domain binding protein|activator protein 1|enhancer-binding protein AP1|v-jun avian sarcoma virus 17 oncogene homolog|v-jun sarcoma virus 17 oncogene homolog; jun oncogene
    Gene Ontology: [View List]
    Invivo
    bait Zhang X (1999)
    Invitro
    bait Zhang X (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FES
  • FPS
  • EG2242
    		•  The BioGRID Database Seperator Oncogene FES, feline sarcoma virus|V-FES feline sarcoma viral/V-FPS fujinami avian sarcoma viral oncogene homolog|c-fes/fps protein|feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog|proto-oncogene c-fes variant 1|proto-oncogene c-fes...
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Rual JF (2005)
    Affinity Capture-Western
    bait Park WY (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PIAS3
  • FLJ14651
  • ZMIZ5
  • EG10401
    		•  The BioGRID Database Seperator protein inhibitor of activated STAT3|zinc finger, MIZ-type containing 5; protein inhibitor of activated STAT, 3
    Gene Ontology: [View List]
    Affinity Capture-MS
    hit Rual JF (2005)
    Affinity Capture-Western
    hit Wang LH (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     HSPCA
  • FLJ31884
  • HSP86
  • HSP90A
  • EG3320
    		•  The BioGRID Database Seperator heat shock 90kD protein 1, alpha|heat shock 90kD protein 1, alpha-like 4|heat shock 90kD protein, alpha-like 4|heat shock 90kDa protein 1, alpha; heat shock protein 90kDa alpha (cytosolic), class A member 1
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Rual JF (2005)
    Affinity Capture-Western
    bait Sato N (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDKN1A
  • CAP20
  • CDKN1
  • CIP1
  • EG1026
    		•  The BioGRID Database Seperator CDK-interaction protein 1|DNA synthesis inhibitor|cyclin-dependent kinase inhibitor 1A|melanoma differentiation associated protein 6|wild-type p53-activated fragment 1; cyclin-dependent kinase inhibitor 1A (p21, Cip1)
    Gene Ontology: [View List]
    Invivo
    hit Coqueret O (2000)
    Affinity Capture-MS
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     EGFR
  • ERBB
  • ERBB1
  • mENA
  • EG1956
    		•  The BioGRID Database Seperator avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Yuan ZL (2004)
    bait Olayioye MA (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MYOD1
  • MYF3
  • MYOD
  • PUM
  • EG4654
    		•  The BioGRID Database Seperator myoblast determination protein 1|myogenic factor 3; myogenic differentiation 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Kataoka Y (2003)
    Reconstituted Complex
    hit Kataoka Y (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCOA1
  • F-SRC-1
  • NCoA-1
  • RIP160
  • EG8648
    		•  The BioGRID Database Seperator Hin-2 protein|PAX3/NCOA1 fusion protein|steroid receptor coactivator-1; nuclear receptor coactivator 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Giraud S (2002)
    Reconstituted Complex
    hit Giraud S (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FRAP1
  • FRAP
  • FRAP2
  • MTOR
  • EG2475
    		•  The BioGRID Database Seperator FK506 binding protein 12-rapamycin associated protein 2|FKBP-rapamycin associated protein|FKBP12-rapamycin complex-associated protein 1|dJ576K7.1 (FK506 binding protein 12-rapamycin associated protein 1)|rapamycin associated protein FRAP2|rapamycin target protein; FK506 binding protein 12-rapamycin...
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Yokogami K (2000)
    Affinity Capture-Western
    bait Kusaba H (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRIP10
  • CIP4
  • HSTP
  • STOT
  • EG9322
    		•  The BioGRID Database Seperator CDC42-interacting protein 4|salt tolerator|thyroid receptor interacting protein 10; thyroid hormone receptor interactor 10
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Chung YH (2004)
    Reconstituted Complex
    bait Chung YH (2004)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JAK1
  • JAK1A
  • JAK1B
  • EG3716
    		•  The BioGRID Database Seperator Janus kinase 1 (a protein tyrosine kinase); janus kinase 1
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Ueda T (2002)
    Affinity Capture-Western
    bait Spiekermann K (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN2
  • PTPT
  • TC-PTP
  • TCELLPTP
  • EG5771
    		•  The BioGRID Database Seperator protein tyrosine phosphatase, non-receptor type 2; T-cell protein tyrosine phosphatase
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Rual JF (2005)
    Affinity Capture-Western
    hit Yamamoto T (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IL2RB
  • P70-75
  • CD122
  • EG3560
    		•  The BioGRID Database Seperator CD122 antigen|OTTHUMP00000028799|high affinity IL-2 receptor beta subunit|interleukin 2 receptor beta; interleukin 2 receptor, beta
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Rual JF (2005)
    Reconstituted Complex
    bait Delespine-Carmagnat M (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GTF2I
  • BAP-135
  • BAP135
  • BTKAP1
  • EG2969
    		•  The BioGRID Database Seperator BTK-associated protein, 135kD|Bruton tyrosine kinase-associated protein 135|Williams-Beuren syndrome chromosome region 6; general transcription factor II, i
    Gene Ontology: [View List]
    Invivo
    bait Kim DW (1998)
    Invitro
    bait Kim DW (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PTPN11
  • BPTP3
  • CFC
  • MGC14433
  • EG5781
    		•  The BioGRID Database Seperator protein tyrosine phosphatase, non-receptor type 11|protein-tyrosine phosphatase 2C; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Rual JF (2005)
    Affinity Capture-Western
    hit Gunaje JJ (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NFKB1
  • DKFZp686C...
  • EBP-1
  • KBF1
  • EG4790
    		•  The BioGRID Database Seperator DNA binding factor KBF1|nuclear factor NF-kappa-B p50 subunit|nuclear factor kappa-B DNA binding subunit|nuclear factor kappa-B, subunit 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
    Gene Ontology: [View List]
    Invivo
    bait Yu Z (2002)
    Invitro
    bait Yu Z (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     JAK3
  • JAK-3
  • JAK3_HUMAN
  • JAKL
  • EG3718
    		•  The BioGRID Database Seperator Janus kinase 3|leukocyte Janus kinase|tyrosine-protein kinase JAK3; Janus kinase 3 (a protein tyrosine kinase, leukocyte)
    Gene Ontology: [View List]
    Invivo
    bait Witthuhn BA (1999)
    Affinity Capture-MS
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PML
  • MYL
  • PP8675
  • RNF71
  • EG5371
    		•  The BioGRID Database Seperator promyelocytic leukemia protein|promyelocytic leukemia, inducer of|tripartite motif protein TRIM19; promyelocytic leukemia
    Gene Ontology: [View List]
    Invivo
    bait Kawasaki A (2003)
    Affinity Capture-MS
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IFNAR1
  • AVP
  • IFN-alpha...
  • IFNAR
  • EG3454
    		•  The BioGRID Database Seperator alpha-type antiviral protein|beta-type antiviral protein|interferon-alpha receptor 1|interferon-alpha/beta receptor alpha chain|interferon-beta receptor 1; interferon (alpha, beta and omega) receptor 1
    Gene Ontology: [View List]
    Invivo
    bait Yang CH (1996)
    Affinity Capture-MS
    bait Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NMI
  • EG9111
    		•  The BioGRID Database Seperator N-myc and STAT interactor|N-myc interactor|N-myc-interactor; N-myc (and STAT) interactor
    Gene Ontology: [View List]
    Invitro
    bait Zhu M (1999)
    Affinity Capture-MS
    hit Rual JF (2005)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     LCK