Homo sapiens
SORL1
C11orf32, LR11, LRP9, SORLA, SorLA-1, gp250
sortilin-related receptor, L(DLR class) A repeats containing
GO Process (26)
GO Function (5)
GO Component (12)
Gene Ontology Biological Process
- negative regulation of MAP kinase activity [ISS]
- negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [IDA, IMP]
- negative regulation of beta-amyloid formation [IDA, IMP]
- negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process [IMP]
- negative regulation of neurofibrillary tangle assembly [ISS]
- negative regulation of neurogenesis [ISS]
- negative regulation of neuron death [ISS]
- negative regulation of protein binding [IDA]
- negative regulation of protein oligomerization [IMP]
- negative regulation of tau-protein kinase activity [ISS]
- positive regulation of ER to Golgi vesicle-mediated transport [IMP]
- positive regulation of choline O-acetyltransferase activity [ISS]
- positive regulation of early endosome to recycling endosome transport [IMP]
- positive regulation of endocytic recycling [IMP]
- positive regulation of protein catabolic process [IDA]
- positive regulation of protein exit from endoplasmic reticulum [IMP]
- positive regulation of protein localization to early endosome [IMP]
- post-Golgi vesicle-mediated transport [IDA]
- protein maturation [IDA]
- protein retention in Golgi apparatus [IDA]
- protein targeting [IDA, IMP]
- protein targeting to Golgi [IDA]
- protein targeting to lysosome [IDA]
- receptor-mediated endocytosis [TAS]
- regulation of smooth muscle cell migration [IDA]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- Golgi cisterna [IDA]
- early endosome [IDA, IMP]
- endoplasmic reticulum [IDA]
- endosome [IDA]
- extracellular space [IDA]
- extracellular vesicular exosome [IDA]
- integral component of plasma membrane [TAS]
- membrane [IDA]
- nuclear envelope lumen [IDA]
- recycling endosome [IMP]
- trans-Golgi network [IDA]
Download Curated Data for this Protein
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- Interactors 153
- Interactions 222
- Network
- PTM Sites 3