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BioGRID | Network Layout for MAP2K4 for Homo sapiens
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MAP2K4

 Homo sapiens
The BioGRID Database Seperator
Aliases: JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SEK1, SERK1, EG6416
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PIXEL
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Description: JNK activating kinase 1|JNK-activated kinase 1|MAP kinase kinase 4|MAPK/ERK kinase 4|SAPK/ERK kinase 1|c-Jun N-terminal kinase kinase 1|dual specificity mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 3 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with MAP2K4

MAP2K4 was identified with 19 protein interactions and 2 genetic interactions
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 MAPK8
  • JNK
  • JNK1
  • JNK1A2
  • EG5599
    		•  The BioGRID Database Seperator JNK1 alpha protein kinase|JNK1 beta protein kinase|c-Jun N-terminal kinase 1|protein kinase JNK1|stress-activated protein kinase JNK1; mitogen-activated protein kinase 8
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Lee CM (2002)
    hit Park HS (2002)
    Biochemical Activity
    hit Chen Z (2001)
    Phenotypic Enhancement
    bait Tournier C (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FLNC
  • ABP-280
  • ABP280A
  • ABPA
  • EG2318
    		•  The BioGRID Database Seperator ABP-L, gamma filamin|actin-binding protein 280|filamin 2|filamin C, gamma (actin-binding protein-280)|gamma actin-binding protein|gamma filamin|gamma-filamin; filamin C, gamma (actin binding protein 280)
    Gene Ontology: [View List]
    Two-hybrid
    hit Marti A (1997)
    Reconstituted Complex
    hit Marti A (1997)
    Affinity Capture-Western
    bait Marti A (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AKT1
  • MGC99656
  • PKB
  • PRKBA
  • EG207
    		•  The BioGRID Database Seperator RAC-alpha serine/threonine-protein kinase|murine thymoma viral (v-akt) oncogene homolog-1|protein kinase B|rac protein kinase alpha; v-akt murine thymoma viral oncogene homolog 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Park HS (2002)
    Biochemical Activity
    bait Park HS (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK8IP3
  • DKFZp762N...
  • FLJ00027
  • JIP3
  • AC012180.8
    		•  The BioGRID Database Seperator C-jun-amino-terminal kinase interacting protein 3|JNK-interacting protein 3|JNK/SAPK-associated protein-1|JNK/stress-activated protein kinase-associated protein 1|homolog of Drosophila Sunday driver 2; mitogen-activated protein kinase 8 interacting protein 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Ito M (1999)
    bait Matsuura H (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K11
  • MGC17114
  • MLK-3
  • MLK3
  • EG4296
    		•  The BioGRID Database Seperator SH3 domain-containing proline-rich kinase|mixed lineage kinase 3|protein-tyrosine kinase PTK1; mitogen-activated protein kinase kinase kinase 11
    Gene Ontology: [View List]
    Biochemical Activity
    bait Merritt SE (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K10
  • MLK2
  • MST
  • EG4294
    		•  The BioGRID Database Seperator MKN28 derived nonreceptor_type serine/threonine kinase|MKN28 kinase|mixed lineage kinase 2; mitogen-activated protein kinase kinase kinase 10
    Gene Ontology: [View List]
    Biochemical Activity
    bait Hirai S (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARRB2
  • ARB2
  • ARR2
  • DKFZp686L...
  • EG409
    		•  The BioGRID Database Seperator arrestin, beta 2
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait McDonald PH (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K4
  • KIAA0213
  • MAPKKK4
  • MEKK4
  • RP3-473J1...
    		•  The BioGRID Database Seperator MAP/ERK kinase kinase 4|MAPK/ERK kinase kinase 4|SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of|dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4)|predicted protein of HQ0412; mitogen-activated protein kinase kinase kinase 4
    Gene Ontology: [View List]
    Biochemical Activity
    bait Chan-Hui PY (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K8
  • COT
  • EST
  • ESTF
  • EG1326
    		•  The BioGRID Database Seperator Cancer Osaka thyroid oncogene|Ewing sarcoma transformant|cot (cancer Osaka thyroid) oncogene|proto-oncogene serine/threoine protein kinase|tumor progression locus-2; mitogen-activated protein kinase kinase kinase 8
    Gene Ontology: [View List]
    Biochemical Activity
    bait Salmeron A (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK14
  • CSBP1
  • CSBP2
  • CSPB1
  • RP1-179N1...
    		•  The BioGRID Database Seperator Csaids binding protein|MAP kinase Mxi2|MAX-interacting protein 2|cytokine suppressive anti-inflammatory drug binding protein|p38 MAP kinase|p38 mitogen activated protein kinase|p38alpha Exip|stress-activated protein kinase 2A; mitogen-activated protein kinase 14
    Gene Ontology: [View List]
    Invitro
    hit Lin A (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP4K2
  • BL44
  • GCK
  • RAB8IP
  • EG5871
    		•  The BioGRID Database Seperator B lymphocyte serine/threonine protein kinase|Rab8 interacting protein|germinal centre kinase (GC kinase); mitogen-activated protein kinase kinase kinase kinase 2
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Yuasa T (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     Flna
  • ABP-280
  • F730004A1...
  • Fln1
  • EG192176
    		•  The BioGRID Database Seperator GENA 379|actin-binding protein 280|dilated pupils 2|filamin A; filamin, alpha
    Gene Ontology: [View List]
    Two-hybrid
    hit Marti A (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SPAG9
  • FLJ13450
  • FLJ14006
  • FLJ34602
  • EG9043
    		•  The BioGRID Database Seperator HLC-4 protein|JNK interacting protein|JNK-associated leucine-zipper protein|JNK/SAPK-associated protein|Max-binding protein|c-Jun NH2-terminal kinase-associated leucine zipper protein|lung cancer oncogene 4|proliferation-inducing gene 6|sperm specific protein|sperm surface protein; sperm associated...
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Lee CM (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP2K7
  • Jnkk2
  • MAPKK7
  • MKK7
  • EG5609
    		•  The BioGRID Database Seperator JNK kinase 2|JNK-activating kinase 2|MAP kinase kinase 7|c-Jun N-terminal kinase kinase 2|dual specificity mitogen-activated protein kinase kinase 7; mitogen-activated protein kinase kinase 7
    Gene Ontology: [View List]
    Phenotypic Enhancement
    hit Fleming Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
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