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[SVG]
ATXN1
Homo sapiens
Aliases:
ATX1, D6S504E, SCA1, EG6310
Description:
OTTHUMP00000039306|olivopontocerebellar ataxia 1, autosomal dominant|spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant, ataxin 1); ataxin 1
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
14 total GO annotations for this record.
[view list]
Function
Process
Component
•
poly(U) binding
(
IDA
)
•
protein self-association
(
IDA
)
•
identical protein binding
(
IPI
)
•
protein C-terminus bindin ...
(
IPI
)
•
transcription repressor a ...
(
IDA
)
•
negative regulation of tr ...
(
IDA
)
•
nuclear export
(
IDA
)
•
RNA processing
(
NAS
)
•
nucleus
(
IDA
)
•
cytoplasm
(
IDA
)
•
nuclear inclusion body
(
IDA
)
•
nucleoplasm
(
IDA
)
•
nuclear matrix
(
IDA
)
•
nuclear RNA export factor ...
(
IDA
)
Download interactions associated with ATXN1
ATXN1 was identified with
12
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
COIL
CLN80
p80-coilin
EG8161
coilin p80; coilin
Gene Ontology:
[View List]
Two-hybrid
hit
Hong S (2003)
Reconstituted Complex
bait/hit
Hong S (2003)
Affinity Capture-Western
hit
Hong S (2003)
GAPDH
G3PD
GAPD
MGC88685
EG2597
aging-associated gene 9 protein|glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase
Gene Ontology:
[View List]
Invitro
hit
Koshy B (1996)
Two-hybrid
hit
Koshy B (1996)
USP7
HAUSP
TEF1
EG7874
Herpes virus-associated ubiquitin-specific protease|ubiquitin specific protease 7|ubiquitin specific protease 7 (herpes virus-associated); ubiquitin specific peptidase 7 (herpes virus-associated)
Gene Ontology:
[View List]
Two-hybrid
hit
Hong S (2002)
Affinity Capture-Western
hit
Hong S (2002)
PQBP1
MRX55
MRXS3
MRXS8
EG10084
nuclear protein containing WW domain 38 kD; polyglutamine binding protein 1
Gene Ontology:
[View List]
Invitro
bait
Okazawa H (2002)
Invivo
bait
Okazawa H (2002)
ZHX1
EG11244
zinc finger and homeodomain protein 1|zinc fingers and homeobox 1|zinc-fingers and homeoboxes 1; zinc fingers and homeoboxes 1
Gene Ontology:
[View List]
Two-hybrid
bait/hit
Yamada K (2003)
UBQLN4
A1U
C1orf6
UBIN
EG56893
ataxin-1 ubiquitin-like interacting protein; ubiquilin 4
Gene Ontology:
[View List]
Two-hybrid
hit
Davidson JD (2000)
ANP32A
C15orf1
I1PP2A
LANP
EG8125
cerebellar leucine rich acidic nuclear protein|inhibitor-1 of protein phosphatase-2A|mapmodulin|putative human HLA class II associated protein I; acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
Gene Ontology:
[View List]
Two-hybrid
bait/hit
Matilla A (1997)
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Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.