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ROCK1
Homo sapiens
Aliases:
P160ROCK, MGC43611, MGC131603, EG6093
Description:
Rho-associated, coiled-coil containing protein kinase 1; p160-ROCK
Links:
[Entrez-Gene]
[OMIM]
[HGNC]
[HPRD]
[Ensembl]
Gene Ontology:
5 total GO annotations for this record.
[view list]
Function
Process
Component
•
protein serine/threonine ...
(
TAS
)
•
identical protein binding
(
IPI
)
•
Rho protein signal transd ...
(
TAS
)
•
actin cytoskeleton organi ...
(
TAS
)
•
protein amino acid phosph ...
(
TAS
)
None Available
Download interactions associated with ROCK1
ROCK1 was identified with
12
protein interactions
Name
Aliases
Description
Evidence Code(s)
Role
Source(s)
RHOA
ARH12
ARHA
RHO12
EG387
Aplysia ras-related homolog 12|oncogene RHO H12|small GTP binding protein RhoA; ras homolog gene family, member A
Gene Ontology:
[View List]
Reconstituted Complex
bait
Riento K (2003)
hit
Leung T (1996)
Two-hybrid
bait
Riento K (2003)
bait
Fujisawa K (1996)
Affinity Capture-Western
bait
Riento K (2003)
Far Western
hit
Fujisawa K (1996)
CFL1
CFL
EG1072
cofilin 1 (non-muscle)
Gene Ontology:
[View List]
Affinity Capture-Western
bait
Maekawa M (1999)
LIMK2
EG3985
LIM domain kinase 2
Gene Ontology:
[View List]
Biochemical Activity
hit
Maekawa M (1999)
GAB1
EG2549
GRB2-associated binding protein 1
Gene Ontology:
[View List]
Co-crystal Structure
hit
Bourguignon LY (2003)
RND3
ARHE
Rho8
RhoE
EG390
ras homolog gene family, member E|small GTP binding protein Rho8; Rho family GTPase 3
Gene Ontology:
[View List]
Reconstituted Complex
bait
Riento K (2003)
PFN2
D3S1319E
PFL
EG5217
profilin 2; profilin-2
Gene Ontology:
[View List]
Affinity Capture-Western
bait/hit
Da Silva JS (2003)
CDC25A
CDC25A2
EG993
M-phase inducer phosphatase 1|cell division cycle 25A|dual specificity phosphatase CDC25A; cell division cycle 25 homolog A (S. pombe)
Gene Ontology:
[View List]
Biochemical Activity
hit
Bhowmick NA (2003)
Copyright © 2009,
Tyers Lab
, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, All Rights Reserved.
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Osprey Network Visualization System
BioGRID: A General Repository for Interaction Datasets.
Chris Stark, Bobby-Joe Breitkreutz, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Mike Tyers.
Nucleic Acids Res. Jan 1;34:D535-9.