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BioGRID | Network Layout for RAF1 for Homo sapiens
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RAF1

 Homo sapiens
The BioGRID Database Seperator
Aliases: CRAF, Raf-1, c-Raf, NS5, EG5894
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: Oncogene RAF1|raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 5 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with RAF1

RAF1 was identified with 149 protein interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 HRAS
  • HRAS1
  • K-ras
  • N-ras
  • EG3265
    		•  The BioGRID Database Seperator H-RasIDX|c-has/bas p21 protein|c-ras-Ki-2 protein|p21 protein; v-Ha-ras Harvey rat sarcoma viral oncogene homolog
    Gene Ontology: [View List]
    Two-hybrid
    bait Stang S (1997)
    hit Germani A (2003)
    hit Yuryev A (2003)
    bait Li W (2000)
    bait Janoueix-Lerosey I (1998)
    bait Boettner B (2000)
    bait Han L (1995)
    bait Romero F (1999)
    bait Morcos P (1996)
    Reconstituted Complex
    hit Mitin NY (2004)
    hit Vargiu P (2004)
    bait Li W (2000)
    bait Jelinek T (1994)
    hit Hu CD (1995)
    hit Rodriguez-Viciana P (1997)
    Affinity Capture-Western
    hit Kiyono M (2000)
    bait Karbowniczek M (2006)
    hit Hu CD (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAB
  • GW128
  • HS1
  • KCIP-1
  • EG7529
    		•  The BioGRID Database Seperator 14-3-3 protein beta/alpha|brain protein 14-3-3, beta isoform|protein 1054|protein kinase C inhibitor protein-1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
    Gene Ontology: [View List]
    Invivo
    bait Vincenz C (1996)
    Invitro
    bait Vincenz C (1996)
    Two-hybrid
    hit Yuryev A (2003)
    hit Yuryev A (2000)
    Reconstituted Complex
    bait Truong AB (2002)
    Affinity Capture-Western
    hit Van Der Hoeven PC (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAZ
  • KCIP-1
  • MGC111427
  • MGC126532
  • EG7534
    		•  The BioGRID Database Seperator 14-3-3 protein/cytosolic phospholipase A2|14-3-3 zeta|phospholipase A2|protein kinase C inhibitor protein-1|tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Clark GJ (1997)
    bait/hit Tzivion G (2000)
    hit Koyama S (1995)
    Affinity Capture-Western
    bait/hit Tzivion G (2000)
    hit Koyama S (1995)
    hit Van Der Hoeven PC (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     GRB10
  • GRB-IR
  • IRBP
  • KIAA0207
  • EG2887
    		•  The BioGRID Database Seperator GRB10 adaptor protein|maternally expressed gene 1; growth factor receptor-bound protein 10
    Gene Ontology: [View List]
    Co-fractionation
    bait Nantel A (1999)
    Two-hybrid
    hit Nantel A (1999)
    hit Nantel A (1998)
    Affinity Capture-Western
    hit Nantel A (1999)
    bait/hit Nantel A (1998)
    Reconstituted Complex
    hit Nantel A (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAG
  • 14-3-3GAMMA
  • EG7532
    		•  The BioGRID Database Seperator tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 14-3-3 gamma
    Gene Ontology: [View List]
    Invivo
    bait Vincenz C (1996)
    Invitro
    bait Vincenz C (1996)
    Affinity Capture-MS
    bait Ewing RM (2007)
    Affinity Capture-Western
    bait Autieri MV (1999)
    hit Van Der Hoeven PC (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAQ
  • 1C5
  • HS1
  • 14-3-3
  • EG10971
    		•  The BioGRID Database Seperator 14-3-3 protein T-cell|14-3-3 protein tau|14-3-3 protein theta|protein tau|tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
    Gene Ontology: [View List]
    Affinity Capture-MS
    bait Ewing RM (2007)
    Affinity Capture-Western
    bait Liu YC (1996)
    hit Van Der Hoeven PC (2000)
    Far Western
    bait Liu YC (1996)
    Reconstituted Complex
    bait Yeung K (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BCL2
  • Bcl-2
  • EG596
    		•  The BioGRID Database Seperator B-cell lymphoma protein 2; B-cell CLL/lymphoma 2
    Gene Ontology: [View List]
    Invivo
    hit Reed JC (1996)
    Invitro
    hit Reed JC (1996)
    Reconstituted Complex
    hit Wang HG (1996)
    Two-hybrid
    bait Wang HG (1996)
    Affinity Capture-Western
    bait Wang HG (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RHEB
  • RHEB2
  • MGC111559
  • EG6009
    		•  The BioGRID Database Seperator GTP-binding protein Rheb|Ras homolog enriched in brain 2; Ras homolog enriched in brain
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Long X (2005)
    bait/hit Karbowniczek M (2004)
    Reconstituted Complex
    bait Long X (2005)
    bait Yee WM (1997)
    Two-hybrid
    bait Yee WM (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAP1A
  • KREV-1
  • KREV1
  • RAP1
  • EG5906
    		•  The BioGRID Database Seperator OTTHUMP00000059089|RAS-related protein RAP1A|Ras-related protein Krev-1; RAP1A, member of RAS oncogene family
    Gene Ontology: [View List]
    Two-hybrid
    bait Han L (1995)
    Co-crystal Structure
    bait Nassar N (1995)
    Reconstituted Complex
    bait Hu CD (1999)
    hit Okada T (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RB1
  • OSRC
  • RB
  • EG5925
    		•  The BioGRID Database Seperator retinoblastoma 1|retinoblastoma susceptibility protein|retinoblastoma suspectibility protein|retinoblastoma-1; retinoblastoma 1 (including osteosarcoma)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Wang S (1998)
    bait Wang S (1999)
    Two-hybrid
    hit Wang S (1998)
    Affinity Capture-Western
    hit Wang S (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     CDC25A
  • CDC25A2
  • EG993
    		•  The BioGRID Database Seperator M-phase inducer phosphatase 1|cell division cycle 25A|dual specificity phosphatase CDC25A; cell division cycle 25 homolog A (S. pombe)
    Gene Ontology: [View List]
    Invivo
    hit Huang TS (1997)
    hit Xia K (1999)
    Affinity Capture-Western
    hit Galaktionov K (1995)
    Reconstituted Complex
    bait Galaktionov K (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK8IP3
  • DKFZp762N...
  • FLJ00027
  • JIP3
  • AC012180.8
    		•  The BioGRID Database Seperator C-jun-amino-terminal kinase interacting protein 3|JNK-interacting protein 3|JNK/SAPK-associated protein-1|JNK/stress-activated protein kinase-associated protein 1|homolog of Drosophila Sunday driver 2; mitogen-activated protein kinase 8 interacting protein 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Kuboki Y (2000)
    bait Ito M (1999)
    Reconstituted Complex
    bait Kuboki Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAK1
  • PAKalpha
  • MGC130000
  • MGC130001
  • EG5058
    		•  The BioGRID Database Seperator p21-activated kinase 1|p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Zang M (2002)
    Reconstituted Complex
    bait Zang M (2002)
    Biochemical Activity
    bait Zang M (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RBL2
  • P130
  • Rb2
  • FLJ26459
  • EG5934
    		•  The BioGRID Database Seperator retinoblastoma-like 2 (p130)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Wang S (1998)
    Two-hybrid
    hit Wang S (1998)
    Affinity Capture-Western
    hit Wang S (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BAG1
  • EG573
    		•  The BioGRID Database Seperator BCL2-associated athanogene 1; BCL2-associated athanogene
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Wang HG (1996)
    Two-hybrid
    hit Wang HG (1996)
    Affinity Capture-Western
    hit Wang HG (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAH
  • YWHA1
  • EG7533
    		•  The BioGRID Database Seperator tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; 14-3-3 eta|tyrosine 3/tryptophan 5 -monooxygenase activation protein, eta polypeptide
    Gene Ontology: [View List]
    Invivo
    bait Vincenz C (1996)
    Affinity Capture-Western
    bait Ichimura T (2002)
    hit Van Der Hoeven PC (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TSC22D3
  • DIP
  • DKFZp313A...
  • DSIPI
  • RP13-364K...
    		•  The BioGRID Database Seperator DSIP-immunoreactive leucine zipper protein|TSC-22 related protein|delta sleep inducing peptide, immunoreactor|glucocorticoid-induced leucine zipper protein; TSC22 domain family, member 3
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Ayroldi E (2002)
    Reconstituted Complex
    hit Ayroldi E (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FYN
  • MGC45350
  • SLK
  • SYN
  • RP1-66H14.1
    		•  The BioGRID Database Seperator OKT3-induced calcium influx regulator|c-syn protooncogene|protein-tyrosine kinase fyn|proto-oncogene tyrosine-protein kinase fyn|src-like kinase|src/yes-related novel|tyrosine kinase p59fyn(T); FYN oncogene related to SRC, FGR, YES
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Cleghon V (1994)
    Reconstituted Complex
    bait Cleghon V (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KRAS
  • C-K-RAS
  • K-RAS2A
  • K-RAS2B
  • EG3845
    		•  The BioGRID Database Seperator K-ras p21 protein|Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog|PR310 c-K-ras oncogene|c-K-ras2 protein|c-Kirsten-ras protein|cellular c-Ki-ras2 proto-oncogene|oncogene KRAS2|transforming protein p21|v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; v-Ki-ras2 Kirsten rat sarcoma...
    Gene Ontology: [View List]
    Two-hybrid
    bait Li W (2000)
    Affinity Capture-Western
    hit Kiyono M (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RRAS2
  • TC21
  • EG22800
    		•  The BioGRID Database Seperator related RAS viral (r-ras) oncogene homolog 2; oncogene TC21
    Gene Ontology: [View List]
    Two-hybrid
    bait Li W (2000)
    Reconstituted Complex
    bait Movilla N (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SRC
  • ASV
  • SRC1
  • c-SRC
  • EG6714
    		•  The BioGRID Database Seperator proto-oncogene tyrosine-protein kinase SRC|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Cleghon V (1994)
    Reconstituted Complex
    bait Cleghon V (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAPK7
  • BMK1
  • ERK4
  • ERK5
  • EG5598
    		•  The BioGRID Database Seperator BMK1 kinase|extracellular-signal-regulated kinase 5; mitogen-activated protein kinase 7
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait English JM (1999)
    Reconstituted Complex
    bait English JM (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PHB
  • EG5245
    		•  The BioGRID Database Seperator prohibitin
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Wang S (1999)
    Reconstituted Complex
    bait/hit Wang S (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     YWHAE
  • 14-3-3E
  • KCIP-1
  • MDCR
  • EG7531
    		•  The BioGRID Database Seperator 14-3-3 epsilon|mitochondrial import stimulation factor L subunit|protein kinase C inhibitor protein-1|tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
    Gene Ontology: [View List]
    Invivo
    bait Conklin DS (1995)
    Invitro
    bait Conklin DS (1995)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PRKCZ
  • PKC2
  • EG5590
    		•  The BioGRID Database Seperator protein kinase C, zeta; OTTHUMP00000044160
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait/hit Van Der Hoeven PC (2000)
    Reconstituted Complex
    hit Van Der Hoeven PC (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     AKT1
  • MGC99656
  • PKB
  • PRKBA
  • EG207
    		•  The BioGRID Database Seperator RAC-alpha serine/threonine-protein kinase|murine thymoma viral (v-akt) oncogene homolog-1|protein kinase B|rac protein kinase alpha; v-akt murine thymoma viral oncogene homolog 1
    Gene Ontology: [View List]
    Biochemical Activity
    bait Zimmermann S (1999)
    Affinity Capture-Western
    hit Zimmermann S (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PEBP4
  • CORK-1
  • CORK1
  • GWTM1933
  • EG157310
    		•  The BioGRID Database Seperator phosphatidylethanolamine-binding protein 4; cousin-of-RKIP 1 protein
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Wang X (2004)
    Reconstituted Complex
    bait Wang X (2004)
    The BioGRID Database Seperator