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BioGRID | Network Layout for RAC1 for Homo sapiens
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RAC1

 Homo sapiens
The BioGRID Database Seperator
Aliases: MIG5, TC-25, p21-Rac1, MGC111543, EG5879
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Description: migration-inducing gene 5|migration-inducing protein 5|ras-related C3 botulinum toxin substrate 1|ras-related C3 botulinum toxin substrate 1 isoform Rac1b|rho family, small GTP binding protein Rac1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Links: [Entrez-Gene]  [OMIM]  [HGNC]  [HPRD]  [Ensembl]  
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Gene Ontology: 12 total GO annotations for this record. [view list]
The BioGRID Database Seperator
PIXEL
The BioGRID Database Seperator
Download interactions associated with RAC1

RAC1 was identified with 100 protein interactions and 1 genetic interactions
Displaying:
 Name Aliases The BioGRID Database Seperator Description
Evidence Code(s)
Role Source(s)
The BioGRID Database Seperator
 NCF2
  • NOXA2
  • P67-PHOX
  • p67phox
  • RP1-127C7.5
    		•  The BioGRID Database Seperator NADPH oxidase activator 2|neutrophil cytosolic factor 2|neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2); neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)
    Gene Ontology: [View List]
    Invitro
    bait Lapouge K (2000)
    bait Dorseuil O (1997)
    Invivo
    bait Dorseuil O (1997)
    Two-hybrid
    bait Dorseuil O (1997)
    Reconstituted Complex
    bait Ahmed S (1998)
    bait Faris SL (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARFIP2
  • POR1
  • EG23647
    		•  The BioGRID Database Seperator ADP-ribosylation factor interacting protein 2|arfaptin 2|partner of RAC1 (arfaptin 2); ADP-ribosylation factor interacting protein 2 (arfaptin 2)
    Gene Ontology: [View List]
    Two-hybrid
    hit Shin OH (2001)
    hit Van Aelst L (1996)
    Reconstituted Complex
    hit Van Aelst L (1996)
    bait Tarricone C (2001)
    Co-crystal Structure
    bait/hit Tarricone C (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PARD6A
  • PAR-6A
  • PAR6alpha
  • TAX40
  • EG50855
    		•  The BioGRID Database Seperator Tax-interacting protein 40|par-6 partitioning defective 6 homolog alpha|partitioning defective-6 homolog alpha|partitioning-defective protein 6; par-6 partitioning defective 6 homolog alpha (C. elegans)
    Gene Ontology: [View List]
    Invitro
    bait Noda Y (2001)
    Invivo
    bait Noda Y (2001)
    Two-hybrid
    bait Noda Y (2001)
    Reconstituted Complex
    bait Qiu RG (2000)
    Affinity Capture-Western
    bait Qiu RG (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IQGAP1
  • HUMORFA01
  • KIAA0051
  • SAR1
  • EG8826
    		•  The BioGRID Database Seperator IQ motif containing GTPase activating protein 1; RasGAP-like with IQ motifs
    Gene Ontology: [View List]
    Invivo
    hit Hart MJ (1996)
    Invitro
    hit Hart MJ (1996)
    Reconstituted Complex
    hit Kuroda S (1996)
    Affinity Capture-Western
    bait Fukata M (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCF1
  • NCF1A
  • NOXO2
  • SH3PXD1A
  • EG653361
    		•  The BioGRID Database Seperator NADPH oxidase organizer 2|neutrophil cytosolic factor 1|neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease, autosomal 1); neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)
    Gene Ontology: [View List]
    Invivo
    bait Dorseuil O (1997)
    Invitro
    bait Dorseuil O (1997)
    Two-hybrid
    bait Dorseuil O (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     SYNJ2
  • INPP5H
  • MGC44422
  • KIAA0348
  • EG8871
    		•  The BioGRID Database Seperator inositol phosphate 5'-phosphatase 2 (synaptojanin 2); synaptojanin 2
    Gene Ontology: [View List]
    Two-hybrid
    hit Malecz N (2000)
    Reconstituted Complex
    bait Malecz N (2000)
    Affinity Capture-Western
    hit Malecz N (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARHGDIA
  • GDIA1
  • RHOGDI
  • MGC117248
  • EG396
    		•  The BioGRID Database Seperator Rho GDP dissociation inhibitor (GDI) alpha
    Gene Ontology: [View List]
    Invivo
    bait Lian LY (2000)
    Two-hybrid
    bait Di-Poi N (2001)
    Affinity Capture-MS
    bait Ewing RM (2007)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MYD88
  • EG4615
    		•  The BioGRID Database Seperator myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Jefferies C (2001)
    Affinity Capture-Western
    bait Jefferies C (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FHOD1
  • FHOS
  • EG29109
    		•  The BioGRID Database Seperator formin homology 2 domain containing 1; FH1/FH2 domain-containing protein
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Westendorf JJ (2001)
    Affinity Capture-Western
    hit Westendorf JJ (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MCF2L
  • ARHGEF14
  • DBS
  • FLJ12122
  • RP11-98F1...
    		•  The BioGRID Database Seperator DBL's big sister|MCF2 transforming sequence-like protein|guanine nucleotide exchange factor DBS; MCF.2 cell line derived transforming sequence-like
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Cheng L (2004)
    Reconstituted Complex
    hit Horii Y (1994)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NCKAP1
  • KIAA0587
  • MGC8981
  • NAP1
  • EG10787
    		•  The BioGRID Database Seperator NCK-associated protein 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Kitamura Y (1997)
    Affinity Capture-Western
    hit Kitamura Y (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAK1
  • PAKalpha
  • MGC130000
  • MGC130001
  • EG5058
    		•  The BioGRID Database Seperator p21-activated kinase 1|p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Katoh H (2003)
    bait Seoh ML (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     STAT3
  • APRF
  • FLJ20882
  • MGC16063
  • EG6774
    		•  The BioGRID Database Seperator DNA-binding protein APRF|acute-phase response factor|signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor)
    Gene Ontology: [View List]
    Invivo
    hit Simon AR (2000)
    Two-hybrid
    hit Simon AR (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     IQGAP2
  • EG10788
    		•  The BioGRID Database Seperator IQ motif containing GTPase activating protein 2
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Brill S (1996)
    Affinity Capture-Western
    bait Brill S (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAK3
  • CDKN1A
  • MRX30
  • OPHN3
  • RP5-914P1...
    		•  The BioGRID Database Seperator OTTHUMP00000062894|oligophrenin-3|p21-activated kinase 3|p21-activated kinase-3; p21 (CDKN1A)-activated kinase 3
    Gene Ontology: [View List]
    Two-hybrid
    hit Shin OH (2001)
    Reconstituted Complex
    hit Shin OH (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TIAM1
  • FLJ36302
  • EG7074
    		•  The BioGRID Database Seperator human T-lymphoma invasion and metastasis inducing TIAM1 protein; T-cell lymphoma invasion and metastasis 1
    Gene Ontology: [View List]
    Co-crystal Structure
    bait Worthylake DK (2000)
    Reconstituted Complex
    bait Gao Y (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     BAIAP2
  • BAP2
  • IRSP53
  • EG10458
    		•  The BioGRID Database Seperator insulin receptor substrate p53; BAI1-associated protein 2
    Gene Ontology: [View List]
    Invivo
    bait Miki H (2002)
    Invitro
    bait Miki H (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     FMNL1
  • C17orf1
  • C17orf1B
  • FHOD4
  • EG752
    		•  The BioGRID Database Seperator CLL-associated antigen KW-13|leukocyte formin; formin-like 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Yayoshi-Yamamoto S (2000)
    Affinity Capture-Western
    hit Yayoshi-Yamamoto S (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RICS
  • GC-GAP
  • GRIT
  • KIAA0712
  • EG9743
    		•  The BioGRID Database Seperator GAB-associated CDC42|RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling|brain-specific Rho GTP-ase-activating protein|rac GTPase activating protein; Rho GTPase-activating protein
    Gene Ontology: [View List]
    Biochemical Activity
    bait Zhao C (2003)
    bait Moon SY (2003)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARHGEF2
  • DKFZp547L...
  • GEF
  • GEF-H1
  • EG9181
    		•  The BioGRID Database Seperator proliferating cell nucleolar antigen p40|rho/rac guanine nucleotide exchange factor 2; rho/rac guanine nucleotide exchange factor (GEF) 2
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Gao Y (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     TRIO
  • tgat
  • EG7204
    		•  The BioGRID Database Seperator triple functional domain (PTPRF interacting)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Gao Y (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     VAV3
  • FLJ40431
  • EG10451
    		•  The BioGRID Database Seperator vav 3 guanine nucleotide exchange factor; vav 3 oncogene
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Movilla N (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAK7
  • KIAA1264
  • MGC26232
  • PAK5
  • RP5-1119D...
    		•  The BioGRID Database Seperator p21-activated kinase 7|protein kinase PAK5|serine/threonine-protein kinase PAK7; p21(CDKN1A)-activated kinase 7
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Dan C (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     MAP3K4
  • KIAA0213
  • MAPKKK4
  • MEKK4
  • RP3-473J1...
    		•  The BioGRID Database Seperator MAP/ERK kinase kinase 4|MAPK/ERK kinase kinase 4|SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of|dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4)|predicted protein of HQ0412; mitogen-activated protein kinase kinase kinase 4
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Gerwins P (1997)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RAC1
  • MIG5
  • TC-25
  • p21-Rac1
  • EG5879
    		•  The BioGRID Database Seperator migration-inducing gene 5|migration-inducing protein 5|ras-related C3 botulinum toxin substrate 1|ras-related C3 botulinum toxin substrate 1 isoform Rac1b|rho family, small GTP binding protein Rac1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Zhang B (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     PAK4
  • EG10298
    		•  The BioGRID Database Seperator p21-activated kinase 4|protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs; p21(CDKN1A)-activated kinase 4
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Dan C (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARHGAP17
  • DKFZp564A...
  • FLJ43368
  • MGC87805
  • EG55114
    		•  The BioGRID Database Seperator RICH1B protein|RhoGAP interacting with CIP4 homologs 1|nadrin|neuron-associated developmentally regulated protein; Rho GTPase activating protein 17
    Gene Ontology: [View List]
    Biochemical Activity
    bait Richnau N (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     OPHN1
  • OPN1
  • MRX60
  • RP6-201G1...
    		•  The BioGRID Database Seperator mental retardation, X-linked 60|oligophrenin-1, Rho-GTPase activating protein; oligophrenin 1
    Gene Ontology: [View List]
    Biochemical Activity
    bait Billuart P (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RGL2
  • HKE1.5
  • KE1.5
  • RAB2L
  • EG5863
    		•  The BioGRID Database Seperator GDS-related protein|RAB2, member RAS oncogene family-like; ral guanine nucleotide dissociation stimulator-like 2
    Gene Ontology: [View List]
    Two-hybrid
    bait Peterson SN (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     RSN
  • CLIP
  • CLIP-170
  • CLIP1
  • EG6249
    		•  The BioGRID Database Seperator Reed-Steinberg cell-expressed intermediate filament-associated protein|cytoplasmic linker 1|restin|restin (Reed-Steinberg cell-expressed intermediate filament-associated protein); CAP-GLY domain containing linker protein 1
    Gene Ontology: [View List]
    Affinity Capture-Western
    bait Fukata M (2002)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     WAS
  • IMD2
  • THC
  • WASP
  • EG7454
    		•  The BioGRID Database Seperator Wiskott-Aldrich syndrome protein|thrombocytopenia 1 (X-linked); Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Kolluri R (1996)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DMPK
  • DM
  • DM1
  • DM1PK
  • EG1760
    		•  The BioGRID Database Seperator DM protein kinase|dystrophia myotonica 1|myotonic dystrophy associated protein kinase|myotonic dystrophy protein kinase|myotonin protein kinase A|thymopoietin homolog; dystrophia myotonica-protein kinase
    Gene Ontology: [View List]
    Reconstituted Complex
    bait/hit Shimizu M (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     NOS2A
  • HEP-NOS
  • INOS
  • NOS
  • EG4843
    		•  The BioGRID Database Seperator NOS, type II|nitric oxide synthase 2A|nitric oxide synthase, macrophage; nitric oxide synthase 2A (inducible, hepatocytes)
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Kuncewicz T (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     ARHGEF4
  • ASEF
  • GEF4
  • STM6
  • EG50649
    		•  The BioGRID Database Seperator APC-stimulated guanine nucleotide exchange factor|Rho guanine nucleotide exchange factor 4; Rho guanine nucleotide exchange factor (GEF) 4
    Gene Ontology: [View List]
    Reconstituted Complex
    bait Kawasaki Y (2000)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DOCK2
  • KIAA0209
  • FLJ46592
  • EG1794
    		•  The BioGRID Database Seperator dedicator of cyto-kinesis 2; dedicator of cytokinesis 2
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Nishihara H (1999)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KIAA0672
  • RICH2
  • NPC-A-10
  • EG9912
    		•  The BioGRID Database Seperator Rho GTPase-activating protein RICH2|RhoGAP interacting with CIP4 homologs protein 2; Rho-type GTPase-activating protein RICH2
    Gene Ontology: [View List]
    Biochemical Activity
    bait Richnau N (2001)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     DOCK1
  • DOCK180
  • ced5
  • RP11-82L9.1
    		•  The BioGRID Database Seperator dedicator of cyto-kinesis 1; dedicator of cytokinesis 1
    Gene Ontology: [View List]
    Reconstituted Complex
    hit Kiyokawa E (1998)
    The BioGRID Database Seperator
    The BioGRID Database Seperator
    The BioGRID Database Seperator
     KTN1
  • CG1
  • KIAA0004
  • KNT
  • EG3895
    		•